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INSMED Inc

INSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001104506

In the last 90 days, INSMED Inc insiders filed 0 open-market purchases and 7 sales; 667 institutions reported holding it in 13F filings for Q2 2026, worth $23.8B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

13F holders, Q4 2025

Institutional positions in INSMED Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
678
+121 vs. Q3 2025
Shares held
217.4M
+6.76M (+3.2%) vs. Q3 2025
Total value
$37.8B
+$7.55B (+24.9%) vs. Q3 2025
New holders
202
241 more added
Sold out
81
180 more reduced

9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting INSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 678 institutions
Q1 2021: 199 institutionsQ2 2021: 203 institutionsQ3 2021: 193 institutionsQ4 2021: 214 institutionsQ1 2022: 224 institutionsQ2 2022: 214 institutionsQ3 2022: 238 institutionsQ4 2022: 225 institutionsQ1 2023: 230 institutionsQ2 2023: 223 institutionsQ3 2023: 252 institutionsQ4 2023: 271 institutionsQ1 2024: 288 institutionsQ2 2024: 378 institutionsQ3 2024: 414 institutionsQ4 2024: 439 institutionsQ1 2025: 442 institutionsQ2 2025: 516 institutionsQ3 2025: 566 institutionsQ4 2025: 678 institutionsQ1 2026: 675 institutionsQ2 2026: 667 institutions
Value heldQ4 2025: $37.8B
Q1 2021: $3.63BQ2 2021: $3.46BQ3 2021: $3.40BQ4 2021: $3.36BQ1 2022: $2.97BQ2 2022: $2.55BQ3 2022: $2.74BQ4 2022: $2.87BQ1 2023: $2.48BQ2 2023: $3.09BQ3 2023: $3.72BQ4 2023: $4.64BQ1 2024: $4.07BQ2 2024: $11.7BQ3 2024: $13.7BQ4 2024: $13.3BQ1 2025: $15.3BQ2 2025: $21.2BQ3 2025: $30.3BQ4 2025: $37.8BQ1 2026: $35.7BQ2 2026: $23.8B
Institutions holding INSM and their total value by quarter
QuarterHoldersValue
Q2 2026667$23.8B
Q1 2026675$35.7B
Q4 2025678$37.8B
Q3 2025566$30.3B
Q2 2025516$21.2B
Q1 2025442$15.3B
Q4 2024439$13.3B
Q3 2024414$13.7B
Q2 2024378$11.7B
Q1 2024288$4.07B
Q4 2023271$4.64B
Q3 2023252$3.72B
Q2 2023223$3.09B
Q1 2023230$2.48B
Q4 2022225$2.87B
Q3 2022238$2.74B
Q2 2022214$2.55B
Q1 2022224$2.97B
Q4 2021214$3.36B
Q3 2021193$3.40B
Q2 2021203$3.46B
Q1 2021199$3.63B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding INSMED Inc; share changes are against Q3 2025.

Institutions holding INSM in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Kemnay Advisory Services Inc.84$14.6K0.00%+84New
TD Private Client Wealth LLC86$15.0K0.00%+56+186.7%Added
Elyxium Wealth, LLC87$15.1K0.00%+87New
Trust Co of Vermont95$16.5K0.00%00.0%Unchanged
Sound Income Strategies, LLC114$18.4K0.00%+94+470.0%Added
WPG Advisers, LLC118$20.5K0.02%−1−0.8%Reduced
Harbour Investments, Inc.121$21.1K0.00%+96+384.0%Added
Contravisory Investment Management, Inc.122$21.2K0.00%−24−16.4%Reduced
McGuire Capital Advisors Inc128$22.3K0.01%+128New
Osbon Capital Management LLC137$23.8K0.02%+137New
CoreCap Advisors, LLC157$27.3K0.00%+157New
Covestor Ltd167$29.0K0.02%00.0%Unchanged
Reflection Asset Management171$29.8K0.02%+171New
Raiffeisen Bank International AG184$32.0K0.00%+184New
Huntington National Bank187$32.5K0.00%−55−22.7%Reduced
Stone House Investment Management, LLC202$35.2K0.01%+2+1.0%Added
Ancora Advisors, LLC214$37.2K0.00%+214New
Massmutual Trust Co FSB218$37.9K0.00%+1+0.5%Added
Wellington-Altus USA Inc.235$40.9K0.03%+235New
Whittier Trust Co of Nevada Inc238$41.7K0.00%−2−0.8%Reduced
Versant Capital Management, Inc240$41.8K0.01%+53+28.3%Added
Umb Bank N A243$42.3K0.00%+10+4.3%Added
HighMark Wealth Management LLC250$43.5K0.02%−5,500−95.7%Reduced
Cullen/Frost Bankers, Inc.256$44.6K0.00%−150−36.9%Reduced
Larson Financial Group LLC256$44.6K0.00%+148+137.0%Added
Towarzystwo Funduszy Inwestycyjnych Pzu SA280$48.7K0.01%+280New
Optiver Holding B.V.315$54.8K0.00%+315New
Clear Street Markets LLC325$56.6K0.01%+325New
International Assets Investment Management, LLC330$57.4K0.00%+330New
RiverPark Advisors, LLC332$57.8K0.02%+71+27.2%Added
Private Wealth Asset Management, LLC333$58.0K0.01%00.0%Unchanged
Ronald Blue Trust, Inc.340$59.2K0.00%−224−39.7%Reduced
Transamerica Financial Advisors, Inc.348$60.6K0.01%+146+72.3%Added
Fifth Third Bancorp358$62.3K0.00%+352+5,866.7%Added
Alphadyne Asset Management LP364$63.4K0.01%+364New
SRS Capital Advisors, Inc.367$63.9K0.00%−422−53.5%Reduced
Geneos Wealth Management Inc.414$72.1K0.00%+341+467.1%Added
Northwestern Mutual Wealth Management Co430$74.8K0.00%+316+277.2%Added
Quest Partners LLC482$83.9K0.00%+195+67.9%Added
Monetary Management Group Inc500$87.0K0.02%00.0%Unchanged
Centiva Capital, LP518$90.2K0.01%+518New
Jones Financial Companies LLLP552$96.1K0.00%+4+0.7%Added
MAI Capital Management555$96.5K0.00%+435+362.5%Added
Hilltop National Bank620$107.9K0.03%00.0%Unchanged
E Fund Management (Hong Kong) Co., Ltd.713$109.8K0.05%+713New
Allworth Financial LP635$110.5K0.00%+108+20.5%Added
CIBC Private Wealth Group, LLC638$111.0K0.00%+459+256.4%Added
Zions Bancorporation, National Association645$112.3K0.01%+645New
ORG Partners LLC657$114.3K0.02%+74+12.7%Added
Berbice Capital Management LLC700$121.8K0.07%+400+133.3%Added
Avanza Fonder AB704$122.5K0.00%+704New
Steward Partners Investment Advisory, LLC709$123.4K0.00%+21+3.1%Added
SageView Advisory Group, LLC742$129.1K0.00%+742New
EverSource Wealth Advisors, LLC747$130.0K0.00%+69+10.2%Added
Spire Wealth Management765$133.1K0.00%−12−1.5%Reduced
Torren Management, LLC832$144.8K0.07%+832New
Pinnacle Wealth Planning Services, Inc.843$146.7K0.02%+843New
Greenline Wealth Management LLC847$147.3K0.15%+847New
SBI Securities Co., Ltd.868$151.1K0.00%+661+319.3%Added
Signaturefd, LLC886$154.2K0.00%+272+44.3%Added
AdvisorNet Financial, Inc922$160.5K0.01%+815+761.7%Added
Bessemer Group Inc968$168.0K0.00%+132+15.8%Added
Chung Wu Investment Group, LLC1,020$177.5K0.15%−700−40.7%Reduced
Manchester Capital Management LLC1,020$177.5K0.02%00.0%Unchanged
Rossby Financial, LCC1,028$178.9K0.06%+726+240.4%Added
Quarry LP1,067$185.7K0.03%−616−36.6%Reduced
LRI Investments, LLC1,073$186.7K0.02%+3+0.3%Added
First Horizon Corp1,106$192.5K0.01%+519+88.4%Added
Rakuten Securities, Inc.1,153$200.7K0.07%+153+15.3%Added
ClearAlpha Technologies LP1,155$201.0K0.57%+1,155New
Keyvantage Wealth, LLC1,163$202.4K0.09%+1,163New
Journey Strategic Wealth LLC1,171$203.8K0.01%−317−21.3%Reduced
Strategic Family Wealth Counselors, L.L.C.1,266$207.0K0.05%+1,266New
Elite Wealth Management, Inc.1,200$208.8K0.06%+1,200New
Earnest Partners LLC1,222$212.7K0.00%+1,222New
Aaron Wealth Advisors1,229$213.9K0.01%+1,229New
Banco BTG Pactual S.A.1,240$215.8K0.04%+1,240New
Wedmont Private Capital1,234$217.2K0.01%+1,234New
New York Life Investment Management LLC1,261$219.5K0.00%−17,916−93.4%Reduced
Fidelis Capital Partners, LLC1,271$221.2K0.02%+1,271New
Charter Capital Management, LLC1,275$221.9K0.11%+1,275New
Lido Advisors, LLC1,553$225.3K0.00%+41+2.7%Added
HB Wealth Management, LLC1,318$229.4K0.00%+1,318New
Brucke Financial, Inc.1,382$240.5K0.13%−2−0.1%Reduced
Wealth Alliance1,393$242.4K0.02%+1,393New
Independent Advisor Alliance1,399$243.5K0.01%−4−0.3%Reduced
Prelude Capital Management, LLC1,401$243.8K0.02%+1,401New
Bayforest Capital Ltd1,421$247.3K0.18%+1,421New
J. Goldman & Co LP1,431$249.1K0.01%−5,940−80.6%Reduced
Coastal Bridge Advisors, LLC1,440$250.6K0.02%+1,440New
Smartleaf Asset Management LLC1,443$251.2K0.01%+657+83.6%Added
Change Path, LLC1,450$252.4K0.01%+1,450New
Allegheny Financial Group LTD1,481$257.8K0.04%+2+0.1%Added
Livforsakringsbolaget Skandia, Omsesidigt1,500$261.0K0.01%+1,500New
Knollwood Investment Advisory, LLC1,501$261.2K0.02%00.0%Unchanged
American Trust1,514$263.5K0.02%−39−2.5%Reduced
Everpar Advisors LLC1,573$273.8K0.10%+120+8.3%Added
Merit Financial Group, LLC1,577$274.5K0.00%+1,577New
Financiere des Professionnels - Fonds d,investissement inc.1,614$280.9K0.02%−4,370−73.0%Reduced
Stratos Wealth Partners, LTD.1,637$284.9K0.00%−1,266−43.6%Reduced