INSMED Inc
INSM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001104506
In the last 90 days, INSMED Inc insiders filed 0 open-market purchases and 7 sales; 667 institutions reported holding it in 13F filings for Q2 2026, worth $23.8B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.
13F holders, Q3 2025
Institutional positions in INSMED Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 566
- +59 vs. Q2 2025
- Shares held
- 210.9M
- +2.45M (+1.2%) vs. Q2 2025
- Total value
- $30.3B
- +$9.37B (+44.7%) vs. Q2 2025
- New holders
- 130
- 194 more added
- Sold out
- 71
- 197 more reduced
9 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting INSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 667 | $23.8B |
| Q1 2026 | 675 | $35.7B |
| Q4 2025 | 678 | $37.8B |
| Q3 2025 | 566 | $30.3B |
| Q2 2025 | 516 | $21.2B |
| Q1 2025 | 442 | $15.3B |
| Q4 2024 | 439 | $13.3B |
| Q3 2024 | 414 | $13.7B |
| Q2 2024 | 378 | $11.7B |
| Q1 2024 | 288 | $4.07B |
| Q4 2023 | 271 | $4.64B |
| Q3 2023 | 252 | $3.72B |
| Q2 2023 | 223 | $3.09B |
| Q1 2023 | 230 | $2.48B |
| Q4 2022 | 225 | $2.87B |
| Q3 2022 | 238 | $2.74B |
| Q2 2022 | 214 | $2.55B |
| Q1 2022 | 224 | $2.97B |
| Q4 2021 | 214 | $3.36B |
| Q3 2021 | 193 | $3.40B |
| Q2 2021 | 203 | $3.46B |
| Q1 2021 | 199 | $3.63B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding INSMED Inc; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Loomis Sayles & Co L P | 492,296 | $70.9M | 0.08% | −301,273−38.0% | Reduced |
| Alkeon Capital Management LLC | 500,000 | $72.0M | 0.33% | 00.0% | Unchanged |
| Bank of Nova Scotia | 506,245 | $72.9M | 0.13% | +506,245 | New |
| UBS Asset Management Americas Inc | 512,749 | $73.8M | 0.02% | −183,212−26.3% | Reduced |
| Wells Fargo & Company | 513,849 | $74.0M | 0.02% | +254,642+98.2% | Added |
| 1832 Asset Management L.P. | 584,800 | $84.2M | 0.14% | +584,800 | New |
| Nuveen, LLC | 588,122 | $84.7M | 0.02% | −865−0.1% | Reduced |
| SEI Investments Co | 593,885 | $85.5M | 0.09% | +160,257+37.0% | Added |
| GW&K Investment Management, LLC | 601,803 | $86.7M | 0.77% | −672,513−52.8% | Reduced |
| Jennison Associates LLC | 602,775 | $86.8M | 0.05% | −112,831−15.8% | Reduced |
| Ensign Peak Advisors, Inc | 642,034 | $92.5M | 0.15% | +77,645+13.8% | Added |
| Macquarie Group Ltd | 649,847 | $93.6M | 0.11% | −481,076−42.5% | Reduced |
| Maverick Capital LtdSuperinvestorMaverick Capital | 656,539 | $94.5M | 1.27% | −147,594−18.4% | Reduced |
| Marshall Wace, LLP | 658,647 | $94.9M | 0.10% | −454,714−40.8% | Reduced |
| Perceptive Advisors LLC | 702,130 | $101.1M | 2.92% | +51,878+8.0% | Added |
| Wellington Management Group LLP | 718,043 | $103.4M | 0.02% | −441,656−38.1% | Reduced |
| Artia Global Partners LP | 732,212 | $105.4M | 18.55% | −20,500−2.7% | Reduced |
| Raymond James Financial Inc | 759,978 | $109.4M | 0.04% | −24,573−3.1% | Reduced |
| Two Sigma Investments, LP | 772,780 | $111.3M | 0.17% | +396,272+105.2% | Added |
| Jane Street Group, LLC | 791,734 | $114.0M | 0.13% | −561,188−41.5% | Reduced |
| Fiera Capital Corp | 809,121 | $116.5M | 0.38% | +61,084+8.2% | Added |
| Goldman Sachs Group Inc | 829,317 | $119.4M | 0.02% | −981,578−54.2% | Reduced |
| FIL Ltd | 851,954 | $122.7M | 0.10% | −313,510−26.9% | Reduced |
| Principal Financial Group Inc | 864,294 | $124.5M | 0.06% | −483,733−35.9% | Reduced |
| Alliancebernstein L.P. | 868,772 | $125.1M | 0.04% | −474,440−35.3% | Reduced |
| Hood River Capital Management LLC | 881,403 | $126.9M | 1.50% | −18,200−2.0% | Reduced |
| Morgan Stanley | 963,631 | $138.8M | 0.01% | −80,160−7.7% | Reduced |
| Charles Schwab Investment Management Inc | 975,279 | $140.4M | 0.02% | −324,289−25.0% | Reduced |
| Eventide Asset Management, LLC | 1,005,107 | $144.7M | 2.38% | −191,387−16.0% | Reduced |
| Nwi Management LP | 1,021,000 | $147.0M | 14.52% | +301,000+41.8% | Added |
| Summit Partners Public Asset Management, LLC | 1,041,845 | $150.0M | 4.89% | +32,908+3.3% | Added |
| Clearbridge Investments, LLC | 1,068,018 | $153.8M | 0.12% | −356,544−25.0% | Reduced |
| Northern Trust Corp | 1,072,942 | $154.5M | 0.02% | +103,142+10.6% | Added |
| Holocene Advisors, LP | 1,083,681 | $156.1M | 0.36% | −933,125−46.3% | Reduced |
| Castle Hook Partners LP | 1,091,405 | $157.2M | 2.38% | +638,749+141.1% | Added |
| Pictet Asset Management Holding SA | 1,140,827 | $163.9M | 0.16% | −412,801−26.6% | Reduced |
| Bank of New York Mellon Corp | 1,138,901 | $164.0M | 0.03% | −58,572−4.9% | Reduced |
| Janus Henderson Group PLC | 1,202,783 | $173.2M | 0.08% | −1,090,359−47.5% | Reduced |
| Adage Capital Partners GP, L.L.C. | 1,252,503 | $180.4M | 0.29% | −1,606,949−56.2% | Reduced |
| Royal Bank of Canada | 1,355,331 | $195.2M | 0.03% | +927,530+216.8% | Added |
| Lord, Abbett & Co. LLC | 1,444,656 | $208.0M | 0.62% | −101,203−6.5% | Reduced |
| Qube Research & Technologies Ltd | 1,544,315 | $222.4M | 0.31% | +462,265+42.7% | Added |
| William Blair Investment Management, LLC | 1,555,057 | $223.9M | 0.58% | −110,545−6.6% | Reduced |
| Integral Health Asset Management, LLC | 1,600,000 | $230.4M | 16.80% | 00.0% | Unchanged |
| Bank of America Corp | 1,601,806 | $230.7M | 0.02% | +375,069+30.6% | Added |
| UBS Group AG | 1,646,239 | $237.1M | 0.05% | +1,352,785+461.0% | Added |
| Invesco Ltd. | 2,003,871 | $288.6M | 0.05% | +107,538+5.7% | Added |
| Citadel Advisors LLC | 2,057,641 | $296.3M | 0.24% | +524,364+34.2% | Added |
| Franklin Resources Inc | 2,139,725 | $308.1M | 0.08% | −210,408−9.0% | Reduced |
| Millennium Management LLC | 2,336,112 | $336.4M | 0.26% | +214,395+10.1% | Added |
| Duquesne Family Office LLCSuperinvestorDuquesne Family Office | 2,423,435 | $349.0M | 8.88% | +170,000+7.5% | Added |
| Ameriprise Financial Inc | 2,721,879 | $392.0M | 0.09% | −236,094−8.0% | Reduced |
| RTW Investments, LP | 3,084,558 | $444.2M | 5.47% | 00.0% | Unchanged |
| Orbis Allan Gray Ltd | 3,250,868 | $468.2M | 2.01% | +1,726,734+113.3% | Added |
| Geode Capital Management, LLC | 3,759,427 | $541.5M | 0.03% | +418,720+12.5% | Added |
| State Street Corp | 3,984,354 | $573.8M | 0.02% | −293,534−6.9% | Reduced |
| Artisan Partners Limited Partnership | 4,937,683 | $711.1M | 1.02% | +1,623,342+49.0% | Added |
| D. E. Shaw & Co., Inc. | 5,657,464 | $814.7M | 0.66% | +2,234,845+65.3% | Added |
| Baker Bros. Advisors LP | 6,703,484 | $965.4M | 6.98% | −1,009,416−13.1% | Reduced |
| Price T Rowe Associates Inc | 6,931,466 | $998.2M | 0.11% | −4,299,239−38.3% | Reduced |
| Capital International Investors | 7,553,853 | $1.09B | 0.18% | +74,994+1.0% | Added |
| FMR LLC | 9,180,963 | $1.32B | 0.07% | +4,087,702+80.3% | Added |
| BlackRock, Inc. | 12,364,904 | $1.78B | 0.03% | +1,222,472+11.0% | Added |
| Vanguard Group Inc | 19,935,820 | $2.87B | 0.04% | +2,291,328+13.0% | Added |
| Darwin Global Management, Ltd. | 20,457,445 | $2.90B | 80.54% | +1,112,824+5.8% | Added |
| JPMorgan Chase & Co | 23,047,676 | $3.32B | 0.21% | +7,411,277+47.4% | Added |
| Deep Track Capital, LP | 0 | $0 | 0.00% | −1,750,000−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −729,597−100.0% | Sold out |
| Alyeska Investment Group, L.P. | 0 | $0 | 0.00% | −603,702−100.0% | Sold out |
| Weiss Asset Management LP | 0 | $0 | 0.00% | −339,825−100.0% | Sold out |
| Cubist Systematic Strategies, LLC | 0 | $0 | 0.00% | −283,102−100.0% | Sold out |
| Healthcare of Ontario Pension Plan Trust Fund | 0 | $0 | 0.00% | −250,100−100.0% | Sold out |
| AXA S.A. | 0 | $0 | 0.00% | −226,603−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −210,647−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −181,554−100.0% | Sold out |
| Panagora Asset Management Inc | 0 | $0 | 0.00% | −149,591−100.0% | Sold out |
| Segall Bryant & Hamill, LLC | 0 | $0 | 0.00% | −119,136−100.0% | Sold out |
| Readystate Asset Management LP | 0 | $0 | 0.00% | −94,052−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −92,717−100.0% | Sold out |
| Polar Asset Management Partners Inc. | 0 | $0 | 0.00% | −92,300−100.0% | Sold out |
| Peregrine Capital Management LLC | 0 | $0 | 0.00% | −88,695−100.0% | Sold out |
| Hudson Bay Capital Management LP | 0 | $0 | 0.00% | −81,743−100.0% | Sold out |
| Iron Triangle Partners LP | 0 | $0 | 0.00% | −70,000−100.0% | Sold out |
| First Light Asset Management, LLC | 0 | $0 | 0.00% | −62,901−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −56,380−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −54,302−100.0% | Sold out |
| EAM Global Investors LLC | 0 | $0 | 0.00% | −50,206−100.0% | Sold out |
| Ally Bridge Group (NY) LLC | 0 | $0 | 0.00% | −47,710−100.0% | Sold out |
| Harbor Capital Advisors, Inc. | 0 | $0 | 0.00% | −46,786−100.0% | Sold out |
| Monashee Investment Management LLC | 0 | $0 | 0.00% | −40,000−100.0% | Sold out |
| Nebula Research & Development LLC | 0 | $0 | 0.00% | −36,661−100.0% | Sold out |
| ArrowMark Colorado Holdings LLC | 0 | $0 | 0.00% | −30,000−100.0% | Sold out |
| Scientech Research LLC | 0 | $0 | 0.00% | −27,642−100.0% | Sold out |
| CSS LLC | 0 | $0 | 0.00% | −27,375−100.0% | Sold out |
| Resolute Capital Asset Partners LLC | 0 | $0 | 0.00% | −27,301−100.0% | Sold out |
| UBS Oconnor LLC | 0 | $0 | 0.00% | −26,301−100.0% | Sold out |
| Winton Group Ltd | 0 | $0 | 0.00% | −22,268−100.0% | Sold out |
| Quantbot Technologies LP | 0 | $0 | 0.00% | −22,067−100.0% | Sold out |
| Bollard Group LLC | 0 | $0 | 0.00% | −17,191−100.0% | Sold out |
| Laurion Capital Management LP | 0 | $0 | 0.00% | −14,347−100.0% | Sold out |