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INSMED Inc

INSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001104506

In the last 90 days, INSMED Inc insiders filed 0 open-market purchases and 7 sales; 667 institutions reported holding it in 13F filings for Q2 2026, worth $23.8B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

13F holders, Q3 2025

Institutional positions in INSMED Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
566
+59 vs. Q2 2025
Shares held
210.9M
+2.45M (+1.2%) vs. Q2 2025
Total value
$30.3B
+$9.37B (+44.7%) vs. Q2 2025
New holders
130
194 more added
Sold out
71
197 more reduced

9 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting INSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 566 institutions
Q1 2021: 199 institutionsQ2 2021: 203 institutionsQ3 2021: 193 institutionsQ4 2021: 214 institutionsQ1 2022: 224 institutionsQ2 2022: 214 institutionsQ3 2022: 238 institutionsQ4 2022: 225 institutionsQ1 2023: 230 institutionsQ2 2023: 223 institutionsQ3 2023: 252 institutionsQ4 2023: 271 institutionsQ1 2024: 288 institutionsQ2 2024: 378 institutionsQ3 2024: 414 institutionsQ4 2024: 439 institutionsQ1 2025: 442 institutionsQ2 2025: 516 institutionsQ3 2025: 566 institutionsQ4 2025: 678 institutionsQ1 2026: 675 institutionsQ2 2026: 667 institutions
Value heldQ3 2025: $30.3B
Q1 2021: $3.63BQ2 2021: $3.46BQ3 2021: $3.40BQ4 2021: $3.36BQ1 2022: $2.97BQ2 2022: $2.55BQ3 2022: $2.74BQ4 2022: $2.87BQ1 2023: $2.48BQ2 2023: $3.09BQ3 2023: $3.72BQ4 2023: $4.64BQ1 2024: $4.07BQ2 2024: $11.7BQ3 2024: $13.7BQ4 2024: $13.3BQ1 2025: $15.3BQ2 2025: $21.2BQ3 2025: $30.3BQ4 2025: $37.8BQ1 2026: $35.7BQ2 2026: $23.8B
Institutions holding INSM and their total value by quarter
QuarterHoldersValue
Q2 2026667$23.8B
Q1 2026675$35.7B
Q4 2025678$37.8B
Q3 2025566$30.3B
Q2 2025516$21.2B
Q1 2025442$15.3B
Q4 2024439$13.3B
Q3 2024414$13.7B
Q2 2024378$11.7B
Q1 2024288$4.07B
Q4 2023271$4.64B
Q3 2023252$3.72B
Q2 2023223$3.09B
Q1 2023230$2.48B
Q4 2022225$2.87B
Q3 2022238$2.74B
Q2 2022214$2.55B
Q1 2022224$2.97B
Q4 2021214$3.36B
Q3 2021193$3.40B
Q2 2021203$3.46B
Q1 2021199$3.63B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding INSMED Inc; share changes are against Q2 2025.

Institutions holding INSM in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Prudential Financial Inc10,970$1.58M0.00%−144,470−92.9%Reduced
F/M Investments LLC11,067$1.59M0.06%−12,494−53.0%Reduced
Parallax Volatility Advisers, L.P.11,144$1.60M0.05%−7,872−41.4%Reduced
Profund Advisors LLC11,373$1.64M0.05%−8,185−41.8%Reduced
MetLife Investment Management11,373$1.64M0.01%+784+7.4%Added
Avidity Partners Management LP11,600$1.67M0.38%−47,400−80.3%Reduced
MYDA Advisors LLC12,000$1.73M0.52%−20,000−62.5%Reduced
Emerald Mutual Fund Advisers Trust12,322$1.77M0.09%−13,102−51.5%Reduced
Emerald Advisers, LLC12,393$1.78M0.06%−871−6.6%Reduced
Engineers Gate Manager LP12,468$1.80M0.02%+12,468New
Quantinno Capital Management LP12,778$1.84M0.01%+8,310+186.0%Added
Boothbay Fund Management, LLC12,817$1.85M0.05%−39,934−75.7%Reduced
Main Management ETF Advisors, LLC13,175$1.90M0.07%+13,175New
Groupama Asset Managment13,175$1.90M0.03%00.0%Unchanged
Federation des caisses Desjardins du Quebec13,223$1.90M0.01%+12,723+2,544.6%Added
O'Shaughnessy Asset Management, LLC13,226$1.90M0.01%+1,886+16.6%Added
Dana Investment Advisors, Inc.13,375$1.93M0.06%−3,723−21.8%Reduced
Granahan Investment Management Inc13,402$1.93M0.08%−102,515−88.4%Reduced
Sectoral Asset Management Inc13,425$1.93M1.19%−1,455−9.8%Reduced
OrbiMed Advisors LLC13,459$1.94M0.05%00.0%Unchanged
Ikarian Capital, LLC13,751$1.98M0.45%−150,000−91.6%Reduced
Point72 Hong Kong Ltd14,021$2.02M0.09%−55,793−79.9%Reduced
Point72 Asia (Singapore) Pte. Ltd.14,371$2.07M0.32%+8,901+162.7%Added
Amalgamated Bank14,533$2.09M0.01%+1,560+12.0%Added
EFG Asset Management (North America) Corp.14,973$2.16M0.28%−48,556−76.4%Reduced
Elo Mutual Pension Insurance Co15,086$2.17M0.04%+15,086New
WCM Investment Management, LLC15,500$2.20M0.00%−138,486−89.9%Reduced
IMC-Chicago, LLC15,282$2.20M0.04%+15,282New
CI Private Wealth, LLC15,560$2.24M0.00%+536+3.6%Added
Next Century Growth Investors LLC15,849$2.28M0.17%+15,849New
Oppenheimer Asset Management Inc.15,853$2.28M0.03%−5,521−25.8%Reduced
Group One Trading, L.P.16,535$2.38M0.07%+16,535New
Keybank National Association16,716$2.41M0.01%+7,257+76.7%Added
Mackenzie Financial Corp16,819$2.42M0.00%+3,238+23.8%Added
SG Americas Securities, LLC17,406$2.51M0.01%+13,305+324.4%Added
West Michigan Advisors, LLC17,619$2.54M0.61%+17,619New
Public Employees Retirement Association of Colorado19,020$2.74M0.01%−238−1.2%Reduced
Campbell & CO Investment Adviser LLC19,060$2.74M0.21%+19,060New
Tobam19,097$2.75M1.00%+19,097New
New York Life Investment Management LLC19,177$2.76M0.02%+497+2.7%Added
Sanctuary Advisors, LLC19,534$2.81M0.02%+8,443+76.1%Added
Simplify Asset Management Inc.19,664$2.83M0.06%+4,128+26.6%Added
Superstring Capital Management LP19,786$2.85M2.81%+5,215+35.8%Added
Fieldview Capital Management, LLC20,229$2.91M0.48%+20,229New
Bellevue Group AG20,251$2.92M0.06%−61,146−75.1%Reduced
Walleye Trading LLC21,085$3.04M0.05%+21,085New
Virginia Retirement Systems Et Al21,265$3.06M0.02%+3,100+17.1%Added
Cerity Partners LLC21,361$3.08M0.00%−6,780−24.1%Reduced
Atria Investments LLC21,413$3.08M0.04%+4,603+27.4%Added
Wolverine Trading, LLC22,095$3.13M0.06%+7,007+46.4%Added
Oak Ridge Investments LLC22,136$3.19M0.21%−12,052−35.3%Reduced
Baird Financial Group, Inc.22,386$3.22M0.01%−3,335−13.0%Reduced
Advisor Group Holdings, Inc.22,748$3.23M0.00%+13,997+159.9%Added
Atomi Financial Group, Inc.23,739$3.42M0.11%+644+2.8%Added
Brown Advisory Inc26,109$3.76M0.00%−553,737−95.5%Reduced
Xponance, Inc.26,418$3.80M0.03%+1,577+6.3%Added
McRae Capital Management Inc27,195$3.92M0.78%+27,195New
Verition Fund Management LLC28,152$4.05M0.02%−65,218−69.8%Reduced
Quantessence Capital LLC28,157$4.05M1.28%−47,571−62.8%Reduced
Landscape Capital Management, L.L.C.28,194$4.06M0.26%+28,194New
Mariner, LLC28,869$4.16M0.01%−506−1.7%Reduced
STRS Ohio29,454$4.24M0.02%+25,187+590.3%Added
Kennedy Capital Management, Inc.30,354$4.37M0.10%+8,457+38.6%Added
Utah Retirement Systems30,729$4.43M0.04%+21,293+225.7%Added
Pathstone Holdings, LLC31,621$4.55M0.02%−7,006−18.1%Reduced
Legato Capital Management LLC34,832$5.02M0.55%−1,247−3.5%Reduced
Calamos Advisors LLC35,215$5.07M0.02%+12,263+53.4%Added
Assetmark, Inc35,294$5.08M0.01%+3,169+9.9%Added
Brinker Capital Investments, LLC36,693$5.28M0.04%−5,124−12.3%Reduced
Guggenheim Capital LLC36,860$5.31M0.04%−4,531−10.9%Reduced
China Universal Asset Management Co., Ltd.37,051$5.34M0.44%+469+1.3%Added
BI Asset Management Fondsmaeglerselskab A/S37,424$5.39M0.05%−47,678−56.0%Reduced
Balyasny Asset Management LLC37,481$5.40M0.01%+37,481New
Quadrature Capital Ltd37,735$5.43M0.06%−58,968−61.0%Reduced
Bamco Inc38,200$5.50M0.01%+1,500+4.1%Added
Acuta Capital Partners, LLC38,592$5.56M5.74%+1,522+4.1%Added
Truist Financial Corp39,063$5.63M0.01%−7,420−16.0%Reduced
Natixis Advisors, L.P.39,450$5.68M0.01%+3,991+11.3%Added
KLP Kapitalforvaltning AS41,000$5.90M0.02%+3,200+8.5%Added
MML Investors Services, LLC41,000$5.90M0.02%−8,018−16.4%Reduced
Cetera Investment Advisers41,171$5.93M0.01%+9,709+30.9%Added
Point72 (DIFC) Ltd41,785$6.02M0.42%+22,205+113.4%Added
Hillsdale Investment Management Inc.42,700$6.15M0.19%−7,000−14.1%Reduced
StemPoint Capital LP43,419$6.25M1.26%−18,159−29.5%Reduced
Thornburg Investment Management Inc44,048$6.34M0.08%−9,200−17.3%Reduced
Polymer Capital Management (HK) LTD44,416$6.40M0.89%+38,524+653.8%Added
Great West Life Assurance Co47,042$6.66M0.01%+792+1.7%Added
Teacher Retirement System of Texas46,637$6.72M0.03%−2,376−4.8%Reduced
Erste Asset Management GmbH47,600$6.74M0.07%00.0%Unchanged
EAM Investors, LLC47,972$6.80M0.78%−11,940−19.9%Reduced
Voleon Capital Management LP47,667$6.86M0.17%+42,900+899.9%Added
Catalyst Funds Management Pty Ltd47,900$6.90M1.05%+725+1.5%Added
DekaBank Deutsche Girozentrale50,000$7.05M0.01%00.0%Unchanged
HighVista Strategies LLC49,949$7.19M1.76%+38,354+330.8%Added
Empowered Funds, LLC50,000$7.20M0.07%+50,000New
Handelsbanken Fonder AB50,181$7.23M0.02%+2,100+4.4%Added
Two Sigma Advisers, LP51,300$7.39M0.01%+33,800+193.1%Added
Picton Mahoney Asset Management51,603$7.43M0.09%−34,001−39.7%Reduced
Connor, Clark & Lunn Investment Management Ltd.51,658$7.44M0.02%−174,484−77.2%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)54,200$7.81M0.02%+2,733+5.3%Added