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Guardant Health, Inc.

GH
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0001576280

In the last 90 days, Guardant Health, Inc. insiders filed 0 open-market purchases and 12 sales; 600 institutions reported holding it in 13F filings for Q2 2026, worth $20.0B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Guardant Health, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
498
+108 vs. Q3 2025
Shares held
131.1M
+8.74M (+7.1%) vs. Q3 2025
Total value
$13.4B
+$5.74B (+75.1%) vs. Q3 2025
New holders
141
156 more added
Sold out
33
149 more reduced

6 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting GH on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 498 institutions
Q1 2021: 420 institutionsQ2 2021: 417 institutionsQ3 2021: 375 institutionsQ4 2021: 397 institutionsQ1 2022: 356 institutionsQ2 2022: 333 institutionsQ3 2022: 328 institutionsQ4 2022: 292 institutionsQ1 2023: 280 institutionsQ2 2023: 301 institutionsQ3 2023: 297 institutionsQ4 2023: 295 institutionsQ1 2024: 258 institutionsQ2 2024: 282 institutionsQ3 2024: 271 institutionsQ4 2024: 298 institutionsQ1 2025: 342 institutionsQ2 2025: 366 institutionsQ3 2025: 396 institutionsQ4 2025: 498 institutionsQ1 2026: 486 institutionsQ2 2026: 600 institutions
Value heldQ4 2025: $13.4B
Q1 2021: $13.9BQ2 2021: $11.1BQ3 2021: $11.8BQ4 2021: $9.24BQ1 2022: $6.11BQ2 2022: $3.75BQ3 2022: $5.04BQ4 2022: $2.53BQ1 2023: $2.17BQ2 2023: $3.95BQ3 2023: $3.21BQ4 2023: $2.99BQ1 2024: $2.30BQ2 2024: $3.32BQ3 2024: $2.86BQ4 2024: $3.65BQ1 2025: $5.10BQ2 2025: $6.47BQ3 2025: $7.65BQ4 2025: $13.4BQ1 2026: $12.5BQ2 2026: $20.0B
Institutions holding GH and their total value by quarter
QuarterHoldersValue
Q2 2026600$20.0B
Q1 2026486$12.5B
Q4 2025498$13.4B
Q3 2025396$7.65B
Q2 2025366$6.47B
Q1 2025342$5.10B
Q4 2024298$3.65B
Q3 2024271$2.86B
Q2 2024282$3.32B
Q1 2024258$2.30B
Q4 2023295$2.99B
Q3 2023297$3.21B
Q2 2023301$3.95B
Q1 2023280$2.17B
Q4 2022292$2.53B
Q3 2022328$5.04B
Q2 2022333$3.75B
Q1 2022356$6.11B
Q4 2021397$9.24B
Q3 2021375$11.8B
Q2 2021417$11.1B
Q1 2021420$13.9B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Guardant Health, Inc.; share changes are against Q3 2025.

Institutions holding GH in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Legal & General Group Plc156,779$16.0M0.00%+5,174+3.4%Added
Agf Management Ltd156,256$16.0M0.07%+156,256New
Rhumbline Advisers155,818$15.9M0.01%−24,349−13.5%Reduced
New York State Common Retirement Fund155,276$15.9M0.02%+78,993+103.6%Added
Principal Financial Group Inc153,782$15.7M0.01%−22,734−12.9%Reduced
Burkehill Global Management, LP150,000$15.3M1.01%+150,000New
Candriam Luxembourg S.C.A.148,406$15.2M0.08%−23,347−13.6%Reduced
Allianz Asset Management GmbH147,569$15.1M0.02%−11,212−7.1%Reduced
Mitsubishi UFJ Trust & Banking Corp145,885$14.9M0.04%−32,424−18.2%Reduced
Royal Bank of Canada142,442$14.5M0.00%−430,349−75.1%Reduced
Algert Global LLC138,732$14.2M0.22%+18,618+15.5%Added
Teachers Retirement System of the State of Kentucky137,471$14.0M0.11%−13,646−9.0%Reduced
Squarepoint Ops LLC136,894$14.0M0.03%+136,894New
Osterweis Capital Management Inc135,936$13.9M0.59%−79,075−36.8%Reduced
Jump Financial, LLC133,103$13.6M0.17%+88,103+195.8%Added
Canada Pension Plan Investment Board131,100$13.4M0.01%−46,200−26.1%Reduced
Neuberger Berman Group LLC131,019$13.4M0.01%+2,618+2.0%Added
Engineers Gate Manager LP127,309$13.0M0.15%−379,641−74.9%Reduced
Hillsdale Investment Management Inc.122,380$12.5M0.34%−33,520−21.5%Reduced
Cerity Partners LLC117,996$12.1M0.02%−12,981−9.9%Reduced
Janus Henderson Group PLC117,501$12.0M0.01%+52,950+82.0%Added
Prudential Financial Inc117,065$12.0M0.01%+44,700+61.8%Added
State of Wisconsin Investment Board115,169$11.8M0.03%−1,794−1.5%Reduced
Aquatic Capital Management LLC115,117$11.8M0.33%−68,459−37.3%Reduced
Farallon Capital Management, L.L.C.109,000$11.1M0.06%+101,000+1,262.5%Added
Susquehanna Portfolio Strategies, LLC108,479$11.1M0.17%00.0%Unchanged
Atika Capital Management LLC108,000$11.0M1.54%−25,000−18.8%Reduced
Capricorn Fund Managers Ltd107,787$11.0M2.65%+71,587+197.8%Added
California State Teachers Retirement System107,030$10.9M0.01%+1,103+1.0%Added
WCM Investment Management, LLC107,931$10.9M0.02%+107,931New
Portolan Capital Management, LLC104,088$10.6M0.57%+104,088New
Voloridge Investment Management, LLC99,175$10.1M0.04%+99,175New
AQR Capital Management LLC98,873$10.1M0.01%+17,296+21.2%Added
Nicholas Investment Partners, LP98,216$10.0M0.73%+14,310+17.1%Added
Exome Asset Management LLC98,182$10.0M4.95%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.93,876$9.59M0.01%−6,228−6.2%Reduced
Silverarc Capital Management, LLC91,914$9.39M1.36%+91,914New
Creative Planning83,805$8.56M0.01%+22,140+35.9%Added
LPL Financial LLC81,147$8.29M0.00%+55,746+219.5%Added
Rhenman & Partners Asset Management AB80,000$8.17M0.76%+30,000+60.0%Added
American Century Companies Inc79,603$8.13M0.00%+1,112+1.4%Added
SWS Partners77,209$7.89M1.90%−17,347−18.3%Reduced
HRT Financial LP77,117$7.88M0.02%+8,770+12.8%Added
Standard Life Aberdeen plc75,124$7.67M0.01%−40,577−35.1%Reduced
Empowered Funds, LLC71,879$7.34M0.12%+65,012+946.7%Added
EAM Investors, LLC71,074$7.26M0.81%−1,421−2.0%Reduced
Acadian Asset Management LLC69,659$7.11M0.01%+69,170+14,145.2%Added
Quantbot Technologies LP68,755$7.02M0.23%+68,755New
Qube Research & Technologies Ltd67,116$6.86M0.01%−502,979−88.2%Reduced
MetLife Investment Management66,922$6.84M0.03%−3,135−4.5%Reduced
Thrivent Financial for Lutherans64,040$6.54M0.01%+64,040New
Jefferies Financial Group Inc.63,918$6.53M0.05%−5,981−8.6%Reduced
Adalta Capital Management LLC63,288$6.46M2.89%00.0%Unchanged
Guggenheim Capital LLC61,970$6.33M0.05%−2,244−3.5%Reduced
F/M Investments LLC58,567$5.98M0.23%+11,363+24.1%Added
Voleon Capital Management LP56,689$5.79M0.12%+56,689New
Calamos Advisors LLC56,468$5.77M0.02%+11,968+26.9%Added
Pathstone Holdings, LLC55,872$5.71M0.02%+5,234+10.3%Added
Comerica Bank54,597$5.58M0.02%+17,931+48.9%Added
Jasper Ridge Partners, L.P.53,125$5.43M0.12%00.0%Unchanged
1832 Asset Management L.P.50,000$5.11M0.01%+50,000New
Intech Investment Management LLC48,283$4.93M0.04%−2,700−5.3%Reduced
Ensign Peak Advisors, Inc47,962$4.90M0.01%−192,461−80.1%Reduced
PDT Partners, LLC45,989$4.70M0.30%−4,351−8.6%Reduced
Ossiam44,816$4.58M0.09%+44,816New
Stifel Financial Corp42,967$4.39M0.00%−1,980−4.4%Reduced
US Bancorp41,746$4.26M0.00%+9,660+30.1%Added
Seven Grand Managers, LLC40,000$4.09M0.31%+40,000New
State of New Jersey Common Pension Fund D39,843$4.07M0.01%−956−2.3%Reduced
Lisanti Capital Growth, LLC38,665$3.95M0.94%+38,665New
Hamilton Wealth, LLC37,784$3.86M0.73%+37,784New
Zurcher Kantonalbank (Zurich Cantonalbank)37,760$3.86M0.01%+3,071+8.9%Added
Employees Retirement System of Texas37,287$3.81M0.03%00.0%Unchanged
One Capital Management, LLC37,181$3.80M0.11%+5,541+17.5%Added
Future Fund LLC36,827$3.76M1.33%−4,459−10.8%Reduced
HighVista Strategies LLC36,758$3.75M0.97%−27,825−43.1%Reduced
Advisor Group Holdings, Inc.35,931$3.67M0.01%+11,305+45.9%Added
Science & Technology Partners, L.P.35,860$3.66M1.02%+35,860New
Mackenzie Financial Corp36,023$3.62M0.00%+13,172+57.6%Added
Pier Capital, LLC33,905$3.46M0.55%−72,315−68.1%Reduced
Handelsbanken Fonder AB33,641$3.44M0.01%+4,000+13.5%Added
Police & Firemen's Retirement System of New Jersey32,586$3.33M0.03%−719−2.2%Reduced
Lagoda Investment Management, L.P.31,505$3.22M1.86%+31,505New
Arizona State Retirement System31,301$3.20M0.02%−1,666−5.1%Reduced
Envestnet Asset Management Inc30,837$3.15M0.00%−10,894−26.1%Reduced
Lazard Asset Management LLC30,585$3.12M0.01%−19,925−39.4%Reduced
Simplify Asset Management Inc.29,581$3.02M0.05%−1,519−4.9%Reduced
State Board of Administration of Florida Retirement System28,750$2.94M0.01%−3,488−10.8%Reduced
HighTower Advisors, LLC28,376$2.90M0.00%−9,524−25.1%Reduced
Vestmark Advisory Solutions, Inc.28,320$2.89M0.04%+28,320New
Bridgewater Associates, LP28,291$2.89M0.01%+24,281+605.5%Added
ProShare Advisors LLC28,136$2.87M0.01%+2,816+11.1%Added
STRS Ohio26,700$2.73M0.01%−3,800−12.5%Reduced
Main Management ETF Advisors, LLC26,622$2.72M0.10%+272+1.0%Added
Prelude Capital Management, LLC26,550$2.71M0.20%−942−3.4%Reduced
Baird Financial Group, Inc.26,518$2.71M0.00%+26,518New
SummitTX Capital, L.P.26,295$2.69M0.08%+26,295New
Janney Montgomery Scott LLC26,280$2.68M0.01%+444+1.7%Added
Legato Capital Management LLC26,076$2.66M0.23%+15,241+140.7%Added
Maven Securities LTD25,000$2.55M0.32%+25,000New