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Guardant Health, Inc.

GH
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0001576280

In the last 90 days, Guardant Health, Inc. insiders filed 0 open-market purchases and 12 sales; 600 institutions reported holding it in 13F filings for Q2 2026, worth $20.0B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Guardant Health, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
498
+108 vs. Q3 2025
Shares held
131.1M
+8.74M (+7.1%) vs. Q3 2025
Total value
$13.4B
+$5.74B (+75.1%) vs. Q3 2025
New holders
141
156 more added
Sold out
33
149 more reduced

6 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting GH on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 498 institutions
Q1 2021: 420 institutionsQ2 2021: 417 institutionsQ3 2021: 375 institutionsQ4 2021: 397 institutionsQ1 2022: 356 institutionsQ2 2022: 333 institutionsQ3 2022: 328 institutionsQ4 2022: 292 institutionsQ1 2023: 280 institutionsQ2 2023: 301 institutionsQ3 2023: 297 institutionsQ4 2023: 295 institutionsQ1 2024: 258 institutionsQ2 2024: 282 institutionsQ3 2024: 271 institutionsQ4 2024: 298 institutionsQ1 2025: 342 institutionsQ2 2025: 366 institutionsQ3 2025: 396 institutionsQ4 2025: 498 institutionsQ1 2026: 486 institutionsQ2 2026: 600 institutions
Value heldQ4 2025: $13.4B
Q1 2021: $13.9BQ2 2021: $11.1BQ3 2021: $11.8BQ4 2021: $9.24BQ1 2022: $6.11BQ2 2022: $3.75BQ3 2022: $5.04BQ4 2022: $2.53BQ1 2023: $2.17BQ2 2023: $3.95BQ3 2023: $3.21BQ4 2023: $2.99BQ1 2024: $2.30BQ2 2024: $3.32BQ3 2024: $2.86BQ4 2024: $3.65BQ1 2025: $5.10BQ2 2025: $6.47BQ3 2025: $7.65BQ4 2025: $13.4BQ1 2026: $12.5BQ2 2026: $20.0B
Institutions holding GH and their total value by quarter
QuarterHoldersValue
Q2 2026600$20.0B
Q1 2026486$12.5B
Q4 2025498$13.4B
Q3 2025396$7.65B
Q2 2025366$6.47B
Q1 2025342$5.10B
Q4 2024298$3.65B
Q3 2024271$2.86B
Q2 2024282$3.32B
Q1 2024258$2.30B
Q4 2023295$2.99B
Q3 2023297$3.21B
Q2 2023301$3.95B
Q1 2023280$2.17B
Q4 2022292$2.53B
Q3 2022328$5.04B
Q2 2022333$3.75B
Q1 2022356$6.11B
Q4 2021397$9.24B
Q3 2021375$11.8B
Q2 2021417$11.1B
Q1 2021420$13.9B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Guardant Health, Inc.; share changes are against Q3 2025.

Institutions holding GH in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Knights of Columbus Asset Advisors LLC24,075$2.46M0.14%−801−3.2%Reduced
KLP Kapitalforvaltning AS24,000$2.45M0.01%+200+0.8%Added
XTX Topco Ltd23,695$2.42M0.06%+20,148+568.0%Added
Delta Investment Management, LLC22,236$2.27M0.39%+22,236New
Values First Advisors, Inc.21,488$2.19M1.14%−9,554−30.8%Reduced
Verition Fund Management LLC21,431$2.19M0.01%−4,219−16.4%Reduced
China Universal Asset Management Co., Ltd.21,081$2.15M0.17%−778−3.6%Reduced
Atom Investors LP20,383$2.08M0.17%+20,383New
Landscape Capital Management, L.L.C.20,085$2.05M0.14%−56,516−73.8%Reduced
Assetmark, Inc19,718$2.01M0.00%+6,461+48.7%Added
Polen Capital Management LLC19,667$2.01M0.01%+2,396+13.9%Added
Simplex Trading, LLC18,994$1.94M0.05%+18,994New
Elo Mutual Pension Insurance Co18,976$1.94M0.03%+18,976New
Havemeyer Place LP18,838$1.92M0.38%+18,838New
Y-Intercept (Hong Kong) Ltd18,715$1.91M0.04%−57,580−75.5%Reduced
Next Century Growth Investors LLC18,484$1.89M0.13%+18,484New
Davy Global Fund Management Ltd18,450$1.88M0.13%+3,380+22.4%Added
Truist Financial Corp17,940$1.83M0.00%+8,831+96.9%Added
D.A. Davidson & Co.17,852$1.82M0.01%+2,005+12.7%Added
Jones Financial Companies LLLP17,379$1.78M0.00%+2,128+14.0%Added
Jacobs Levy Equity Management, Inc17,357$1.77M0.01%−787−4.3%Reduced
Entropy Technologies, LP17,093$1.75M0.09%+9,979+140.3%Added
SG Americas Securities, LLC17,047$1.74M0.00%+17,047New
Gotham Asset Management, LLC16,984$1.73M0.01%+16,984New
Baader Bank INC16,900$1.73M0.14%+16,900New
LMR Partners LLP16,800$1.72M0.02%+10,000+147.1%Added
Quadrature Capital Ltd16,504$1.69M0.02%+16,504New
Occudo Quantitative Strategies LP16,488$1.68M0.11%+12,506+314.1%Added
Pensionmark Financial Group, LLC16,290$1.66M0.03%+16,290New
Penserra Capital Management LLC15,720$1.60M0.02%+15,720New
Harvest Investment Services, LLC14,417$1.47M0.28%+14,417New
Numerai GP LLC13,876$1.42M0.17%+13,876New
Oak Ridge Investments LLC13,535$1.38M0.08%−350−2.5%Reduced
IMC-Chicago, LLC13,428$1.37M0.02%+13,428New
Campbell & CO Investment Adviser LLC12,757$1.30M0.06%−6,271−33.0%Reduced
Great West Life Assurance Co12,137$1.24M0.00%−18,945−61.0%Reduced
Public Employees Retirement Association of Colorado11,753$1.20M0.00%00.0%Unchanged
Illinois Municipal Retirement Fund11,720$1.20M0.02%+11,720New
Rockefeller Capital Management L.P.11,618$1.19M0.00%+6,678+135.2%Added
New York Life Investment Management LLC11,016$1.13M0.01%+11,016New
Investors Towarzystwo Funduszy Inwestycyjnych Spolka Akcyjna11,000$1.12M0.43%+200+1.9%Added
BankChampaign, National Association10,854$1.11M1.10%+10,854New
Cambridge Investment Research Advisors, Inc.10,845$1.11M0.00%−136−1.2%Reduced
Cinctive Capital Management LP10,811$1.10M0.06%−110,319−91.1%Reduced
O'Shaughnessy Asset Management, LLC10,801$1.10M0.01%+3,857+55.5%Added
OP Asset Management Ltd10,789$1.10M0.01%+2,342+27.7%Added
Mangrove Partners10,737$1.10M0.09%+10,737New
State of Wyoming10,626$1.09M0.12%−121−1.1%Reduced
Morris Retirement Advisors, LLC10,596$1.08M0.45%−4,761−31.0%Reduced
Exchange Traded Concepts, LLC10,418$1.06M0.01%−5,166−33.1%Reduced
Banque Cantonale Vaudoise10,290$1.05M0.04%−3,823−27.1%Reduced
JustInvest LLC10,187$1.04M0.01%+1,207+13.4%Added
Brandywine Managers, LLC10,133$1.03M0.51%−100−1.0%Reduced
Ameritas Investment Partners, Inc.10,034$1.02M0.03%+54+0.5%Added
Harbor Capital Advisors, Inc.9,936$1.01M0.08%+9,936New
Xponance, Inc.9,630$983.6K0.01%+199+2.1%Added
Virginia Retirement Systems Et Al9,550$975.4K0.01%−1,250−11.6%Reduced
Federation des caisses Desjardins du Quebec9,501$970.4K0.00%+9,201+3,067.0%Added
Quantitative Investment Management, LLC9,363$956.0K0.09%−3,510−27.3%Reduced
B. Metzler seel. Sohn & Co. AG8,918$910.9K0.01%+8,918New
Cetera Investment Advisers8,765$895.3K0.00%−246−2.7%Reduced
Bank of Montreal8,632$881.7K0.00%+426+5.2%Added
DekaBank Deutsche Girozentrale45,000$879.0K0.00%00.0%Unchanged
HSBC Holdings PLC8,451$863.5K0.00%+2,743+48.1%Added
Los Angeles Capital Management LLC9,130$843.7K0.00%+9,130New
CAPROCK Group, Inc.8,186$836.1K0.02%+301+3.8%Added
Wealthcare Advisory Partners LLC8,135$830.9K0.02%−122−1.5%Reduced
CIBC World Markets Corp8,040$821.2K0.00%+8,040New
NEOS Investment Management LLC8,030$820.2K0.00%−2,255−21.9%Reduced
Ieq Capital, LLC7,969$814.0K0.00%00.0%Unchanged
Tema ETFs LLC7,915$808.4K0.06%−2,370−23.0%Reduced
Meeder Asset Management Inc7,886$805.5K0.04%+7,843+18,239.5%Added
Boothbay Fund Management, LLC7,737$790.3K0.02%−3,927−33.7%Reduced
The PNC Financial Services Group, Inc.7,715$788.0K0.00%+3,699+92.1%Added
Edgestream Partners, L.P.7,651$781.5K0.02%−30,949−80.2%Reduced
FORA Capital, LLC7,589$775.1K0.09%+7,589New
Guardian Partners Inc.7,000$743.0K0.06%+7,000New
Van Eck Associates Corp7,134$729.0K0.00%+3,503+96.5%Added
Teacher Retirement System of Texas7,120$727.2K0.00%−7,484−51.2%Reduced
Northwest & Ethical Investments L.P.7,200$724.3K0.02%+7,200New
Guyasuta Investment Advisors Inc7,000$715.0K0.04%+260+3.9%Added
ADAR1 Capital Management, LLC7,000$715.0K0.05%+1,000+16.7%Added
Connective Portfolio Management, LLC7,000$715.0K1.29%+7,000New
MSH Capital Advisors LLC6,937$708.5K0.15%−5,916−46.0%Reduced
Pier 88 Investment Partners LLC6,820$696.6K0.16%−9,830−59.0%Reduced
Canton Hathaway, LLC6,780$692.5K0.13%−1,170−14.7%Reduced
Inceptionr LLC6,733$687.7K0.19%−3,993−37.2%Reduced
Mirae Asset Global Investments Co., Ltd.6,603$674.4K0.00%+1,782+37.0%Added
Fiduciary Alliance LLC6,599$674.0K0.04%−490−6.9%Reduced
Commonwealth Equity Services, LLC6,546$668.6K0.00%+354+5.7%Added
Graham Capital Management, L.P.6,385$652.2K0.02%−2,265−26.2%Reduced
Alta Wealth Advisors LLC6,359$649.5K0.22%−137−2.1%Reduced
Thoroughbred Financial Services, LLC6,354$648.0K0.04%+6,354New
Bokf, NA6,271$640.5K0.01%−3,958−38.7%Reduced
Keybank National Association6,189$632.1K0.00%−72−1.1%Reduced
Toroso Investments, LLC6,141$627.2K0.00%+1,644+36.6%Added
National Bank of Canada6,106$623.5K0.00%+6,106New
FIL Ltd6,020$614.9K0.00%+2,699+81.3%Added
Qsemble Capital Management, LP5,882$600.8K0.05%−4,606−43.9%Reduced
Susquehanna Fundamental Investments, LLC5,775$589.9K0.02%00.0%Unchanged