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Guardant Health, Inc.

GH
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0001576280

In the last 90 days, Guardant Health, Inc. insiders filed 0 open-market purchases and 12 sales; 599 institutions reported holding it in 13F filings for Q2 2026, worth $20.0B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Guardant Health, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
498
+108 vs. Q3 2025
Shares held
131.1M
+8.74M (+7.1%) vs. Q3 2025
Total value
$13.4B
+$5.74B (+75.1%) vs. Q3 2025
New holders
141
156 more added
Sold out
33
149 more reduced

6 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting GH on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 498 institutions
Q1 2021: 420 institutionsQ2 2021: 417 institutionsQ3 2021: 375 institutionsQ4 2021: 397 institutionsQ1 2022: 356 institutionsQ2 2022: 333 institutionsQ3 2022: 328 institutionsQ4 2022: 292 institutionsQ1 2023: 280 institutionsQ2 2023: 301 institutionsQ3 2023: 297 institutionsQ4 2023: 295 institutionsQ1 2024: 258 institutionsQ2 2024: 282 institutionsQ3 2024: 271 institutionsQ4 2024: 298 institutionsQ1 2025: 342 institutionsQ2 2025: 366 institutionsQ3 2025: 396 institutionsQ4 2025: 498 institutionsQ1 2026: 486 institutionsQ2 2026: 599 institutions
Value heldQ4 2025: $13.4B
Q1 2021: $13.9BQ2 2021: $11.1BQ3 2021: $11.8BQ4 2021: $9.24BQ1 2022: $6.11BQ2 2022: $3.75BQ3 2022: $5.04BQ4 2022: $2.53BQ1 2023: $2.17BQ2 2023: $3.95BQ3 2023: $3.21BQ4 2023: $2.99BQ1 2024: $2.30BQ2 2024: $3.32BQ3 2024: $2.86BQ4 2024: $3.65BQ1 2025: $5.10BQ2 2025: $6.47BQ3 2025: $7.65BQ4 2025: $13.4BQ1 2026: $12.5BQ2 2026: $20.0B
Institutions holding GH and their total value by quarter
QuarterHoldersValue
Q2 2026599$20.0B
Q1 2026486$12.5B
Q4 2025498$13.4B
Q3 2025396$7.65B
Q2 2025366$6.47B
Q1 2025342$5.10B
Q4 2024298$3.65B
Q3 2024271$2.86B
Q2 2024282$3.32B
Q1 2024258$2.30B
Q4 2023295$2.99B
Q3 2023297$3.21B
Q2 2023301$3.95B
Q1 2023280$2.17B
Q4 2022292$2.53B
Q3 2022328$5.04B
Q2 2022333$3.75B
Q1 2022356$6.11B
Q4 2021397$9.24B
Q3 2021375$11.8B
Q2 2021417$11.1B
Q1 2021420$13.9B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Guardant Health, Inc.; share changes are against Q3 2025.

Institutions holding GH in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
American Capital Advisory, LLC1$1030.00%+1New
Dunhill Financial, LLC2$1600.00%+2New
Cullen/Frost Bankers, Inc.2$2040.00%+2New
West Branch Capital LLC2$2050.00%00.0%Unchanged
Raffa Wealth Management, LLC4$4090.00%00.0%Unchanged
Rialto Wealth Management, LLC4$4090.00%00.0%Unchanged
DV Trading LLC4$4090.00%+4New
Massmutual Trust Co FSB5$5110.00%+1+25.0%Added
Central Trust Co5$5110.00%+5New
Marquette Asset Management, LLC5$5110.00%+5New
CVA Family Office, LLC5$5110.00%+5New
Atlantic Private Wealth, LLC5$5110.00%+5New
Rossby Financial, LCC5$5110.00%+5New
Optima Capital LLC5$5110.00%+5New
HFM Investment Advisors, LLC6$6130.00%+2+50.0%Added
Whittier Trust Co7$7860.00%00.0%Unchanged
TD Capital Management LLC8$8170.00%00.0%Unchanged
Concord Wealth Partners8$8170.00%00.0%Unchanged
Bay Harbor Wealth Management, LLC8$8170.00%+2+33.3%Added
Capital Advisors, Ltd. LLC8$1.00K0.00%00.0%Unchanged
SHP Wealth Management10$1.02K0.00%+10New
Beaird Harris Wealth Management, LLC10$1.02K0.00%00.0%Unchanged
True Wealth Design, LLC11$1.12K0.00%−1−8.3%Reduced
Creative Financial Designs Inc12$1.23K0.00%00.0%Unchanged
Zions Bancorporation, National Association12$1.23K0.00%+12New
Cape Investment Advisory, Inc.12$1.23K0.00%+12New
Key Financial Inc13$1.33K0.00%00.0%Unchanged
Curio Wealth, LLC14$1.43K0.00%+14New
Godfrey Financial Associates, Inc.15$1.53K0.00%+15New
DiNuzzo Private Wealth, Inc.17$1.74K0.00%+6+54.5%Added
Bare Financial Services, Inc18$1.84K0.00%−9−33.3%Reduced
Strategic Investment Solutions, Inc.20$2.04K0.00%00.0%Unchanged
Turning Point Benefit Group, Inc.21$2.15K0.00%+21New
Greenline Wealth Management LLC25$2.56K0.00%+25New
Dogwood Wealth Management LLC29$2.96K0.00%+29New
Essential Partners LLC30$3.06K0.00%+2+7.1%Added
MV Capital Management, Inc.31$3.17K0.00%00.0%Unchanged
ORG Partners LLC33$3.37K0.00%+28+560.0%Added
Quadrant Capital Group LLC37$3.78K0.00%00.0%Unchanged
Fortitude Family Office, LLC38$3.88K0.00%+5+15.2%Added
Strategic Wealth Advisors LLC40$4.00K0.00%+40New
Bellevue Asset Management, LLC40$4.09K0.00%00.0%Unchanged
Rakuten Securities, Inc.44$4.49K0.00%+21+91.3%Added
Prestige Wealth Management Group LLC46$4.70K0.00%+46New
Aster Capital Management (DIFC) Ltd48$4.90K0.00%+48New
Bessemer Group Inc50$5.00K0.00%00.0%Unchanged
Tidemark, LLC50$5.11K0.00%00.0%Unchanged
Bell Investment Advisors, Inc55$5.62K0.00%00.0%Unchanged
JFS Wealth Advisors, LLC56$5.72K0.00%+25+80.6%Added
Morton Brown Family Wealth, LLC58$5.92K0.00%00.0%Unchanged
Versant Capital Management, Inc61$6.23K0.00%00.0%Unchanged
CoreCap Advisors, LLC61$6.23K0.00%00.0%Unchanged
International Assets Investment Management, LLC63$6.43K0.00%+63New
Harbour Investments, Inc.76$7.76K0.00%+65+590.9%Added
Huntington National Bank81$8.27K0.00%−1−1.2%Reduced
Parkside Financial Bank & Trust84$8.58K0.00%00.0%Unchanged
SJS Investment Consulting Inc.88$8.99K0.00%+83+1,660.0%Added
Quarry LP89$9.09K0.00%−608−87.2%Reduced
Bartlett & Co. Wealth Management LLC92$9.40K0.00%00.0%Unchanged
Torren Management, LLC93$9.50K0.00%+93New
Hantz Financial Services, Inc.100$10.0K0.00%+100New
Hurley Capital, LLC100$10.2K0.01%00.0%Unchanged
UMA Financial Services, Inc.105$10.7K0.00%+18+20.7%Added
SageView Advisory Group, LLC111$11.3K0.00%+111New
Adirondack Trust Co115$11.7K0.00%00.0%Unchanged
Contravisory Investment Management, Inc.124$12.7K0.00%+124New
Quent Capital, LLC132$13.5K0.00%00.0%Unchanged
WPG Advisers, LLC139$14.2K0.01%+139New
Keating Financial Advisory Services, Inc.145$14.8K0.00%+145New
Root Financial Partners, LLC159$16.2K0.00%+41+34.7%Added
Farther Finance Advisors, LLC165$16.9K0.00%−2−1.2%Reduced
Basecamp Wealth Advisors LLC167$17.1K0.00%+167New
Rothschild Investment LLC191$19.5K0.00%+11+6.1%Added
Country Trust Bank200$20.4K0.00%00.0%Unchanged
Financial Network Wealth Advisors LLC224$22.9K0.02%+50+28.7%Added
Medallion Wealth Advisors, LLC225$23.0K0.01%00.0%Unchanged
Optiver Holding B.V.242$24.7K0.00%−526−68.5%Reduced
V-Square Quantitative Management LLC261$26.7K0.00%+261New
Chesapeake Asset Management LLC270$27.6K0.02%+270New
RiverPark Advisors, LLC302$30.8K0.01%+302New
Close Asset Management Ltd300$31.0K0.00%−160−34.8%Reduced
Thurston, Springer, Miller, Herd & Titak, Inc.305$31.2K0.01%+305New
MAI Capital Management328$33.5K0.00%+6+1.9%Added
PFS Partners, LLC330$33.7K0.02%00.0%Unchanged
Covestor Ltd329$34.0K0.02%00.0%Unchanged
Elyxium Wealth, LLC344$35.1K0.01%+344New
Parallel Advisors, LLC352$36.0K0.00%+219+164.7%Added
Elequin Capital LP363$37.1K0.00%+363New
Daiwa Securities Group Inc.390$40.0K0.00%−18−4.4%Reduced
GWM Advisors LLC392$40.0K0.00%−1,000−71.8%Reduced
EFG International AG400$40.9K0.00%+400New
First Pacific Financial420$42.9K0.01%+420New
HighMark Wealth Management LLC550$56.2K0.02%00.0%Unchanged
Kestra Advisory Services, LLC553$56.5K0.00%+553New
Itau Unibanco Holding S.A.584$59.6K0.00%+584New
Sound Income Strategies, LLC572$64.1K0.00%−14−2.4%Reduced
SRS Capital Advisors, Inc.733$74.9K0.00%+279+61.5%Added
Signaturefd, LLC789$80.6K0.00%−112−12.4%Reduced
Schroder Investment Management Group806$81.1K0.00%00.0%Unchanged
Sterling Capital Management LLC797$81.4K0.00%+506+173.9%Added