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Guardant Health, Inc.

GH
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0001576280

In the last 90 days, Guardant Health, Inc. insiders filed 0 open-market purchases and 12 sales; 599 institutions reported holding it in 13F filings for Q2 2026, worth $20.0B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Guardant Health, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
498
+108 vs. Q3 2025
Shares held
131.1M
+8.74M (+7.1%) vs. Q3 2025
Total value
$13.4B
+$5.74B (+75.1%) vs. Q3 2025
New holders
141
156 more added
Sold out
33
149 more reduced

6 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting GH on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 498 institutions
Q1 2021: 420 institutionsQ2 2021: 417 institutionsQ3 2021: 375 institutionsQ4 2021: 397 institutionsQ1 2022: 356 institutionsQ2 2022: 333 institutionsQ3 2022: 328 institutionsQ4 2022: 292 institutionsQ1 2023: 280 institutionsQ2 2023: 301 institutionsQ3 2023: 297 institutionsQ4 2023: 295 institutionsQ1 2024: 258 institutionsQ2 2024: 282 institutionsQ3 2024: 271 institutionsQ4 2024: 298 institutionsQ1 2025: 342 institutionsQ2 2025: 366 institutionsQ3 2025: 396 institutionsQ4 2025: 498 institutionsQ1 2026: 486 institutionsQ2 2026: 599 institutions
Value heldQ4 2025: $13.4B
Q1 2021: $13.9BQ2 2021: $11.1BQ3 2021: $11.8BQ4 2021: $9.24BQ1 2022: $6.11BQ2 2022: $3.75BQ3 2022: $5.04BQ4 2022: $2.53BQ1 2023: $2.17BQ2 2023: $3.95BQ3 2023: $3.21BQ4 2023: $2.99BQ1 2024: $2.30BQ2 2024: $3.32BQ3 2024: $2.86BQ4 2024: $3.65BQ1 2025: $5.10BQ2 2025: $6.47BQ3 2025: $7.65BQ4 2025: $13.4BQ1 2026: $12.5BQ2 2026: $20.0B
Institutions holding GH and their total value by quarter
QuarterHoldersValue
Q2 2026599$20.0B
Q1 2026486$12.5B
Q4 2025498$13.4B
Q3 2025396$7.65B
Q2 2025366$6.47B
Q1 2025342$5.10B
Q4 2024298$3.65B
Q3 2024271$2.86B
Q2 2024282$3.32B
Q1 2024258$2.30B
Q4 2023295$2.99B
Q3 2023297$3.21B
Q2 2023301$3.95B
Q1 2023280$2.17B
Q4 2022292$2.53B
Q3 2022328$5.04B
Q2 2022333$3.75B
Q1 2022356$6.11B
Q4 2021397$9.24B
Q3 2021375$11.8B
Q2 2021417$11.1B
Q1 2021420$13.9B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Guardant Health, Inc.; share changes are against Q3 2025.

Institutions holding GH in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Vanguard Group Inc12,160,768$1.24B0.02%+251,939+2.1%Added
BlackRock, Inc.11,317,714$1.16B0.02%−111,601−1.0%Reduced
Price T Rowe Associates Inc5,636,078$575.7M0.06%+1,414,441+33.5%Added
Invesco Ltd.5,315,934$543.0M0.05%+386,391+7.8%Added
Baillie Gifford & Co4,890,026$499.5M0.42%−237,666−4.6%Reduced
Capital International Investors3,528,656$360.4M0.06%−1,160,585−24.7%Reduced
Franklin Resources Inc3,361,547$343.3M0.08%+435,232+14.9%Added
Geode Capital Management, LLC3,213,657$328.3M0.02%+277,001+9.4%Added
Deep Track Capital, LP2,800,000$286.0M6.52%−1,354,086−32.6%Reduced
State Street Corp2,795,727$285.6M0.01%+7,950+0.3%Added
Goldman Sachs Group Inc2,627,709$268.4M0.04%+1,121,499+74.5%Added
Eventide Asset Management, LLC2,511,091$256.5M4.01%−810,247−24.4%Reduced
Fuller & Thaler Asset Management, Inc.2,441,730$249.4M0.84%+72,162+3.0%Added
FMR LLC2,396,433$244.8M0.01%+1,572,168+190.7%Added
Two Sigma Advisers, LP2,382,300$243.3M0.47%+269,500+12.8%Added
Two Sigma Investments, LP2,171,903$221.8M0.33%+368,572+20.4%Added
Driehaus Capital Management LLC2,143,193$218.9M1.49%−9,122−0.4%Reduced
Federated Hermes, Inc.2,031,562$207.5M0.35%+255,193+14.4%Added
Lord, Abbett & Co. LLC1,988,983$203.2M0.62%+465,348+30.5%Added
UBS Asset Management Americas Inc1,915,581$195.7M0.04%−346,288−15.3%Reduced
Alliancebernstein L.P.1,901,308$194.2M0.06%+1,761,785+1,262.7%Added
UBS Group AG1,710,169$174.7M0.03%+253,118+17.4%Added
Point72 Asset Management, L.P.1,499,169$153.1M0.24%+1,396,754+1,363.8%Added
RTW Investments, LP1,481,033$151.3M1.52%00.0%Unchanged
Charles Schwab Investment Management Inc1,457,676$148.9M0.02%+41,792+3.0%Added
Bank of New York Mellon Corp1,366,157$139.5M0.02%+413,106+43.3%Added
Alyeska Investment Group, L.P.1,343,654$137.2M0.39%−487,664−26.6%Reduced
Norges Bank1,258,072$128.5M0.01%+1,258,072New
Jennison Associates LLC1,170,337$119.5M0.07%−300,957−20.5%Reduced
Morgan Stanley1,154,299$117.9M0.01%+171,755+17.5%Added
Northern Trust Corp1,102,791$112.6M0.01%−51,970−4.5%Reduced
Erste Asset Management GmbH1,045,917$106.8M0.90%+340,700+48.3%Added
Temasek Holdings (Private) Ltd1,044,097$106.6M0.34%00.0%Unchanged
Bank of America Corp1,017,646$103.9M0.01%+143,788+16.5%Added
Hood River Capital Management LLC978,515$99.9M1.10%+721,622+280.9%Added
Cadian Capital Management, LP922,628$94.2M6.81%−1,218,563−56.9%Reduced
Emerald Advisers, LLC861,824$88.0M2.71%−11,379−1.3%Reduced
Summit Partners Public Asset Management, LLC851,958$87.0M2.45%+741,958+674.5%Added
Ameriprise Financial Inc762,595$77.9M0.02%+455,114+148.0%Added
ARK Investment Management LLCSuperinvestorARK Invest691,647$70.6M0.47%−103,587−13.0%Reduced
Sumitomo Mitsui Trust Holdings, Inc.640,505$65.4M0.04%−113,649−15.1%Reduced
Nikko Asset Management Americas, Inc.640,295$65.4M0.76%−113,649−15.1%Reduced
Manufacturers Life Insurance Company, The635,935$64.8M0.05%+1,484+0.2%Added
BNP Paribas Arbitrage, SA624,776$63.8M0.04%+567,008+981.5%Added
D. E. Shaw & Co., Inc.623,057$63.6M0.05%+589,710+1,768.4%Added
Allspring Global Investments Holdings, LLC618,599$62.9M0.10%−12,256−1.9%Reduced
Renaissance Technologies LLC602,300$61.5M0.10%+70,453+13.2%Added
Fred Alger Management, LLC589,656$60.2M0.24%−48,831−7.6%Reduced
Millennium Management LLC583,807$59.6M0.04%−294,769−33.6%Reduced
Citadel Advisors LLC564,342$57.6M0.04%+259,822+85.3%Added
Westfield Capital Management Co LP539,190$55.1M0.23%+539,190New
Emerald Mutual Fund Advisers Trust523,932$53.5M2.61%−32,077−5.8%Reduced
Jane Street Group, LLC513,620$52.5M0.06%+436,641+567.2%Added
Balyasny Asset Management LLC505,608$51.6M0.10%−27,769−5.2%Reduced
Aristotle Atlantic Partners, LLC494,386$50.5M2.31%−429,348−46.5%Reduced
Nuveen, LLC473,451$48.4M0.01%+18,492+4.1%Added
Adage Capital Partners GP, L.L.C.464,905$47.5M0.07%+312,783+205.6%Added
Jupiter Asset Management Ltd421,328$43.0M0.34%+213,512+102.7%Added
Wellington Management Group LLP406,519$41.5M0.01%−2,842,566−87.5%Reduced
Casdin Capital, LLC380,000$38.8M2.41%+280,000+280.0%Added
Victory Capital Management Inc377,045$38.5M0.02%−96,988−20.5%Reduced
Blue Water Life Science Advisors, LLC355,047$36.3M22.76%−50,600−12.5%Reduced
Deutsche Bank AG336,428$34.4M0.01%+576+0.2%Added
Barclays PLC336,274$34.3M0.01%+58,838+21.2%Added
PBU - The Pension Fund of Early Childhood & Youth Educators335,854$34.3M0.49%+335,854New
Voya Investment Management LLC330,429$33.8M0.03%−25,992−7.3%Reduced
Raymond James Financial Inc328,632$33.2M0.01%−1,261−0.4%Reduced
Dimensional Fund Advisors LP306,553$31.3M0.01%+241,539+371.5%Added
Man Group plc295,804$30.2M0.06%−455,729−60.6%Reduced
First Light Asset Management, LLC294,751$30.1M2.30%+14,750+5.3%Added
Artisan Partners Limited Partnership290,352$29.7M0.05%+290,352New
Universal- Beteiligungs- und Servicegesellschaft mbH287,454$29.2M0.05%−13,995−4.6%Reduced
Eagle Health Investments LP284,100$29.0M6.38%00.0%Unchanged
Styrax Capital, LP281,589$28.8M2.20%+281,589New
Trexquant Investment LP274,039$28.0M0.25%−110,691−28.8%Reduced
First Turn Management, LLC271,685$27.7M3.17%+271,685New
JPMorgan Chase & Co271,039$27.7M0.00%−222,782−45.1%Reduced
Connor, Clark & Lunn Investment Management Ltd.266,492$27.2M0.07%+121,132+83.3%Added
SEI Investments Co261,942$26.8M0.03%+60,615+30.1%Added
Walleye Capital LLC254,302$26.0M0.15%+185,509+269.7%Added
Segall Bryant & Hamill, LLC244,266$24.9M0.34%−60,881−20.0%Reduced
Massachusetts Financial Services Co237,481$24.3M0.01%−65,841−21.7%Reduced
Sicart Associates LLC228,203$23.3M6.18%−1,880−0.8%Reduced
Swiss National Bank221,300$22.6M0.01%+5,200+2.4%Added
California Public Employees Retirement System215,092$22.0M0.01%+8,268+4.0%Added
Wells Fargo & Company214,177$21.9M0.00%+100,192+87.9%Added
Nomura Asset Management International Inc.212,947$21.8M0.03%+212,947New
Russell Investments Group, Ltd.211,392$21.6M0.02%+16,157+8.3%Added
Rathbone Brothers plc205,113$21.0M0.08%+5,025+2.5%Added
Axiom Investors LLC203,642$20.8M0.18%+203,642New
Citigroup Inc188,888$19.3M0.01%+169,674+883.1%Added
TD Asset Management Inc181,048$18.5M0.01%−7,762−4.1%Reduced
First Trust Advisors LP179,731$18.4M0.01%−6,462−3.5%Reduced
Marshall Wace, LLP171,206$17.5M0.02%−70,100−29.1%Reduced
Pictet Asset Management Holding SA166,384$16.9M0.02%−89,386−34.9%Reduced
Castleark Management LLC165,043$16.9M0.49%+4,970+3.1%Added
Perceptive Advisors LLC160,000$16.3M0.30%+160,000New
Picton Mahoney Asset Management159,029$16.2M0.18%+159,029New
Granite Investment Partners, LLC158,199$16.2M0.96%−27,102−14.6%Reduced
Polar Capital Holdings Plc157,485$16.1M0.07%+157,485New