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Guardant Health, Inc.

GH
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0001576280

In the last 90 days, Guardant Health, Inc. insiders filed 0 open-market purchases and 12 sales; 600 institutions reported holding it in 13F filings for Q2 2026, worth $20.0B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Guardant Health, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
498
+108 vs. Q3 2025
Shares held
131.1M
+8.74M (+7.1%) vs. Q3 2025
Total value
$13.4B
+$5.74B (+75.1%) vs. Q3 2025
New holders
141
156 more added
Sold out
33
149 more reduced

6 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting GH on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 498 institutions
Q1 2021: 420 institutionsQ2 2021: 417 institutionsQ3 2021: 375 institutionsQ4 2021: 397 institutionsQ1 2022: 356 institutionsQ2 2022: 333 institutionsQ3 2022: 328 institutionsQ4 2022: 292 institutionsQ1 2023: 280 institutionsQ2 2023: 301 institutionsQ3 2023: 297 institutionsQ4 2023: 295 institutionsQ1 2024: 258 institutionsQ2 2024: 282 institutionsQ3 2024: 271 institutionsQ4 2024: 298 institutionsQ1 2025: 342 institutionsQ2 2025: 366 institutionsQ3 2025: 396 institutionsQ4 2025: 498 institutionsQ1 2026: 486 institutionsQ2 2026: 600 institutions
Value heldQ4 2025: $13.4B
Q1 2021: $13.9BQ2 2021: $11.1BQ3 2021: $11.8BQ4 2021: $9.24BQ1 2022: $6.11BQ2 2022: $3.75BQ3 2022: $5.04BQ4 2022: $2.53BQ1 2023: $2.17BQ2 2023: $3.95BQ3 2023: $3.21BQ4 2023: $2.99BQ1 2024: $2.30BQ2 2024: $3.32BQ3 2024: $2.86BQ4 2024: $3.65BQ1 2025: $5.10BQ2 2025: $6.47BQ3 2025: $7.65BQ4 2025: $13.4BQ1 2026: $12.5BQ2 2026: $20.0B
Institutions holding GH and their total value by quarter
QuarterHoldersValue
Q2 2026600$20.0B
Q1 2026486$12.5B
Q4 2025498$13.4B
Q3 2025396$7.65B
Q2 2025366$6.47B
Q1 2025342$5.10B
Q4 2024298$3.65B
Q3 2024271$2.86B
Q2 2024282$3.32B
Q1 2024258$2.30B
Q4 2023295$2.99B
Q3 2023297$3.21B
Q2 2023301$3.95B
Q1 2023280$2.17B
Q4 2022292$2.53B
Q3 2022328$5.04B
Q2 2022333$3.75B
Q1 2022356$6.11B
Q4 2021397$9.24B
Q3 2021375$11.8B
Q2 2021417$11.1B
Q1 2021420$13.9B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Guardant Health, Inc.; share changes are against Q3 2025.

Institutions holding GH in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Brinker Capital Investments, LLC5,731$585.4K0.00%+5,731New
Headlands Technologies LLC5,629$574.9K0.05%+5,629New
Mariner, LLC5,611$572.5K0.00%+1,690+43.1%Added
Yorktown Management & Research Co Inc5,550$566.9K0.45%00.0%Unchanged
Navellier & Associates Inc5,412$552.8K0.06%−2,342−30.2%Reduced
Oppenheimer & Co Inc5,362$547.7K0.01%+5,362New
Ethic Inc.5,358$547.3K0.01%+1,503+39.0%Added
Quantinno Capital Management LP5,291$540.4K0.00%+232+4.6%Added
Swiss Life Asset Management Ltd5,290$540.3K0.00%+63+1.2%Added
Paradigm Financial Partners, LLC5,157$526.7K0.05%−10−0.2%Reduced
M&T Bank Corp5,118$523.0K0.00%+5,118New
Sanctuary Advisors, LLC5,093$520.2K0.00%−1,197−19.0%Reduced
Schonfeld Strategic Advisors LLC5,081$519.0K0.00%−16,401−76.3%Reduced
Odyssean, LLC5,077$518.6K0.37%+5,077New
Amundi5,011$511.8K0.00%+5,011New
Jag Capital Management, LLC4,960$506.6K0.06%+987+24.8%Added
TD Waterhouse Canada Inc.4,856$495.8K0.00%−35−0.7%Reduced
Glenmede Trust Co NA4,853$495.7K0.00%+4,853New
Inspire Advisors, LLC4,816$491.9K0.05%−6,968−59.1%Reduced
Abel Hall, LLC4,533$463.0K0.11%+751+19.9%Added
Gsa Capital Partners LLP4,528$462.0K0.04%−17,454−79.4%Reduced
CIBC Asset Management Inc4,519$461.6K0.00%+583+14.8%Added
Kestra Private Wealth Services, LLC4,471$456.7K0.01%−50−1.1%Reduced
Mercer Global Advisors Inc4,357$445.0K0.00%+490+12.7%Added
Perpetual Ltd4,337$443.0K0.01%+4,337New
Fifth Third Bancorp4,105$419.3K0.00%−85−2.0%Reduced
Everence Capital Management Inc4,080$417.0K0.02%00.0%Unchanged
Mendel Money Management3,910$399.4K0.17%−545−12.2%Reduced
Wealthspire Advisors, LLC3,886$396.9K0.00%+235+6.4%Added
Amalgamated Bank3,818$390.0K0.00%−52−1.3%Reduced
RWC Asset Management LLP3,775$385.6K0.02%−2,071−35.4%Reduced
Nisa Investment Advisors, LLC3,430$350.3K0.00%−101−2.9%Reduced
World Equity Group, Inc.3,405$347.8K0.10%+3,405New
Alamea Verwaltungs GmbH3,010$343.3K0.23%−1,984−39.7%Reduced
NBC Securities, Inc.3,339$341.0K0.03%−115−3.3%Reduced
Susquehanna International Group, LLP3,306$337.7K0.00%−28,380−89.6%Reduced
McGuire Investment Group, LLC3,200$326.8K0.03%+3,200New
Wulff, Hansen & Co.3,185$325.3K0.27%+3,185New
KBC Group NV3,134$320.0K0.00%00.0%Unchanged
Wesbanco Bank Inc3,016$308.1K0.01%+3,016New
Bellevue Group AG3,004$306.8K0.01%+1,051+53.8%Added
Blueshift Asset Management, LLC2,877$293.9K0.08%+2,877New
Green Alpha Advisors, LLC2,860$292.1K0.27%−1,546−35.1%Reduced
Global Retirement Partners, LLC2,843$290.4K0.01%+2,681+1,654.9%Added
Wealthfront Advisers LLC2,838$289.9K0.00%+2,838New
OneAscent Financial Services LLC2,835$289.6K0.03%+2,835New
Virtus ETF Advisers LLC2,750$280.9K0.13%+2,750New
Tower Research Capital LLC (TRC)2,743$280.2K0.01%+138+5.3%Added
Resources Investment Advisors, LLC.2,678$273.5K0.00%+2,678New
Quest Partners LLC2,654$271.1K0.02%+2,654New
Stephens Inc2,644$270.1K0.00%+2,644New
GF Fund Management Co. Ltd.2,541$259.5K0.00%−142−5.3%Reduced
Mount Yale Investment Advisors, LLC2,501$255.5K0.01%+2,501New
Pinnacle Wealth Planning Services, Inc.2,485$253.8K0.03%+2,485New
Ascent Wealth Partners, LLC2,479$253.2K0.03%+2,479New
EntryPoint Capital, LLC2,474$252.7K0.10%+2,474New
Wealth Enhancement Advisory Services, LLC2,222$249.6K0.00%+2,222New
Keel Point, LLC2,409$246.1K0.01%+2,409New
Profund Advisors LLC2,359$240.9K0.01%+2,359New
Atria Investments LLC2,357$240.7K0.00%−1,457−38.2%Reduced
CWM, LLC2,309$236.0K0.00%+289+14.3%Added
Skopos Labs, Inc.2,317$234.9K0.01%+2,317New
Abacus Wealth Partners, LLC2,273$232.2K0.02%+2,273New
Captrust Financial Advisors2,257$230.6K0.00%+2,257New
Natixis2,250$229.8K0.00%−55,650−96.1%Reduced
Motley Fool Asset Management LLC2,244$229.2K0.01%+2,244New
Capstone Investment Advisors, LLC2,239$228.7K0.00%−35,560−94.1%Reduced
Eurizon Capital SGR S.p.A.2,233$224.4K0.00%+2,233New
Eastern Bank2,160$220.6K0.00%+139+6.9%Added
Argent Trust Co2,136$218.2K0.01%+2,136New
TCW Group Inc2,120$216.5K0.00%+2,120New
AlphaGrep UK Ltd2,107$215.2K0.07%+2,107New
Aigen Investment Management, LP2,105$215.0K0.05%+2,105New
Norden Group LLC2,072$211.6K0.02%+2,072New
Leonteq Securities AG2,069$211.3K0.01%+41+2.0%Added
Forefront Wealth Management Inc.2,000$204.3K0.15%+2,000New
SBI Securities Co., Ltd.1,949$199.1K0.01%−135−6.5%Reduced
CIBC Private Wealth Group, LLC1,918$195.9K0.00%+16+0.8%Added
Kimelman & Baird, LLC1,900$194.1K0.01%00.0%Unchanged
Harvest Fund Management Co., Ltd1,864$190.0K0.01%00.0%Unchanged
NBT Bank N A1,825$186.4K0.01%00.0%Unchanged
Northwestern Mutual Wealth Management Co1,819$185.8K0.00%−528−22.5%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.1,586$162.0K0.00%+459+40.7%Added
Smartleaf Asset Management LLC1,606$161.6K0.01%+510+46.5%Added
McGuire Capital Advisors Inc1,514$154.6K0.10%+1,514New
Kemnay Advisory Services Inc.1,424$145.4K0.02%+1,424New
EverSource Wealth Advisors, LLC1,242$126.9K0.00%+209+20.2%Added
Danske Bank A/S1,200$122.6K0.00%+200+20.0%Added
JNBA Financial Advisors1,141$116.5K0.01%00.0%Unchanged
Clearstead Advisors, LLC1,141$116.5K0.00%+1,093+2,277.1%Added
IMA Wealth, Inc.1,116$114.0K0.01%00.0%Unchanged
Steward Partners Investment Advisory, LLC1,052$107.5K0.00%−75−6.7%Reduced
HM Payson & Co1,000$102.1K0.00%00.0%Unchanged
Bullseye Asset Management LLC1,000$102.0K0.05%+1,000New
Allworth Financial LP893$91.2K0.00%+49+5.8%Added
IFP Advisors, Inc844$86.2K0.00%+217+34.6%Added
Flagship Harbor Advisors, LLC809$82.6K0.00%+809New
GAMMA Investing LLC808$82.5K0.00%+226+38.8%Added
Sterling Capital Management LLC797$81.4K0.00%+506+173.9%Added
Schroder Investment Management Group806$81.1K0.00%00.0%Unchanged