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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

Q3 2025 vs. Q2 2025

How the institutions holding Denali Therapeutics Inc. changed between Q2 2025 and Q3 2025.

All holders in Q3 2025All holders in Q2 2025

13F holders of DNLI: Q2 2025 compared with Q3 2025
MeasureQ2 2025Of which not filed for Q3 2025Q3 2025Change
Holders2314240+13
Shares137.6M4.38M135.5M+2.28M (+1.7%)
Value$1.93B$61.2M$1.97B+$103.6M (+5.6%)

4 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (35)

Institutions that held Denali Therapeutics Inc. at the end of Q3 2025 but not at the end of Q2 2025.

Institutions new to DNLI in Q3 2025
InstitutionSharesValue% of portfolio
Foresite Capital Management VI LLC1,000,000$14.5M5.61%
AXA Investment Managers S.A.294,732$4.28M0.01%
Lynx1 Capital Management LP261,687$3.80M0.77%
Boxer Capital Management, LLC250,000$3.63M1.16%
Qube Research & Technologies Ltd227,990$3.31M0.00%
Schonfeld Strategic Advisors LLC226,203$3.28M0.02%
Jump Financial, LLC166,399$2.42M0.03%
Squarepoint Ops LLC80,518$1.17M0.00%
XTX Topco Ltd65,345$948.8K0.05%
Aquatic Capital Management LLC56,237$816.6K0.02%
Jacobs Levy Equity Management, Inc45,969$667.5K0.00%
Jennison Associates LLC45,445$659.9K0.00%
Cantor Fitzgerald, L. P.45,000$653.4K0.01%
SG Americas Securities, LLC38,201$555.0K0.00%
Quantinno Capital Management LP24,707$358.7K0.00%
EntryPoint Capital, LLC24,058$349.3K0.14%
Oxford Asset Management LLP22,231$322.8K0.11%
CIBC Bancorp USA Inc.14,118$205.0K0.00%
LPL Financial LLC10,648$154.6K0.00%
Intrust Bank NA10,575$153.5K0.01%
Caption Management, LLC7,366$107.0K0.01%
Quarry LP4,375$63.5K0.02%
Johnson Financial Group, Inc.1,975$28.7K0.00%
Rockefeller Capital Management L.P.1,083$15.7K0.00%
Quadrant Capital Group LLC782$11.4K0.00%
Groupe la Francaise620$7.67K0.00%
Meeder Asset Management Inc206$2.99K0.00%
Halbert Hargrove Global Advisors, LLC104$1.51K0.00%
TD Private Client Wealth LLC71$1.03K0.00%
Root Financial Partners, LLC70$1.02K0.00%
Guerra Advisors Inc50$7260.00%
Point72 (DIFC) Ltd43$6220.00%
Advisory Services Network, LLC39$5660.00%
Sunbelt Securities, Inc.22$3190.00%
Cloud Capital Management, LLC2$00.00%

Sold out (22)

Institutions that held Denali Therapeutics Inc. at the end of Q2 2025 and filed for Q3 2025 without it.

Institutions that sold out of DNLI in Q3 2025
InstitutionShares, Q2 2025Value, Q2 2025
AXA S.A.293,853$4.11M
Twinbeech Capital LP210,370$2.94M
Soleus Capital Management, L.P.182,110$2.55M
Polar Asset Management Partners Inc.91,600$1.28M
Man Group plc70,028$979.7K
Skandinaviska Enskilda Banken AB (publ)43,245$605.0K
Dark Forest Capital Management LP28,433$397.8K
Capital Fund Management S.A.21,871$306.0K
Virtu Financial LLC18,438$258.0K
Prelude Capital Management, LLC15,940$223.0K
NEOS Investment Management LLC15,174$212.3K
Tema ETFs LLC15,174$212.3K
STRS Ohio14,300$200.1K
Caxton Associates LLP14,229$199.1K
Headlands Technologies LLC1,847$25.8K
Point72 Asia (Singapore) Pte. Ltd.1,369$19.2K
Mount Yale Investment Advisors, LLC201$2.81K
SRS Capital Advisors, Inc.52$728
Bare Financial Services, Inc36$504
CIBC Private Wealth Group, LLC35$490
Skopos Labs, Inc.31$434
WealthTrak Capital Management LLC10$140

Not filed for Q3 2025 yet (4)

Institutions that held Denali Therapeutics Inc. at the end of Q2 2025 and haven't filed a 13F for Q3 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding DNLI in Q2 2025 that haven't filed for Q3 2025
InstitutionShares, Q2 2025Value, Q2 2025
Norges Bank3,947,387$55.2M
Camber Capital Management LP400,000$5.60M
CIBC World Markets Corp16,318$228.3K
E Fund Management Co., Ltd.13,612$190.4K