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Compass Therapeutics, Inc.

CMPX
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001738021

In the last 90 days, Compass Therapeutics, Inc. insiders filed 1 open-market purchase and 0 sales; 215 institutions reported holding it in 13F filings for Q2 2026, worth $363.4M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Compass Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
173
+49 vs. Q3 2025
Shares held
164.1M
+13.1M (+8.7%) vs. Q3 2025
Total value
$881.5M
+$352.8M (+66.7%) vs. Q3 2025
New holders
59
60 more added
Sold out
10
34 more reduced

1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CMPX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 173 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 37 institutionsQ1 2022: 34 institutionsQ2 2022: 34 institutionsQ3 2022: 38 institutionsQ4 2022: 55 institutionsQ1 2023: 73 institutionsQ2 2023: 73 institutionsQ3 2023: 76 institutionsQ4 2023: 77 institutionsQ1 2024: 78 institutionsQ2 2024: 82 institutionsQ3 2024: 79 institutionsQ4 2024: 92 institutionsQ1 2025: 108 institutionsQ2 2025: 103 institutionsQ3 2025: 125 institutionsQ4 2025: 173 institutionsQ1 2026: 201 institutionsQ2 2026: 215 institutions
Value heldQ4 2025: $881.5M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $201.6MQ1 2022: $85.4MQ2 2022: $163.9MQ3 2022: $145.6MQ4 2022: $401.4MQ1 2023: $266.5MQ2 2023: $287.7MQ3 2023: $176.7MQ4 2023: $134.3MQ1 2024: $187.2MQ2 2024: $93.4MQ3 2024: $169.6MQ4 2024: $147.0MQ1 2025: $206.1MQ2 2025: $281.5MQ3 2025: $528.7MQ4 2025: $881.5MQ1 2026: $921.3MQ2 2026: $363.4M
Institutions holding CMPX and their total value by quarter
QuarterHoldersValue
Q2 2026215$363.4M
Q1 2026201$921.3M
Q4 2025173$881.5M
Q3 2025125$528.7M
Q2 2025103$281.5M
Q1 2025108$206.1M
Q4 202492$147.0M
Q3 202479$169.6M
Q2 202482$93.4M
Q1 202478$187.2M
Q4 202377$134.3M
Q3 202376$176.7M
Q2 202373$287.7M
Q1 202373$266.5M
Q4 202255$401.4M
Q3 202238$145.6M
Q2 202234$163.9M
Q1 202234$85.4M
Q4 202137$201.6M
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Compass Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding CMPX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
NEOS Investment Management LLC101,676$546.0K0.00%+101,676New
Citadel Advisors LLC105,682$567.5K0.00%−127,589−54.7%Reduced
SG Americas Securities, LLC106,533$572.0K0.00%−42,780−28.7%Reduced
Creative Planning108,144$580.7K0.00%+47,217+77.5%Added
Deutsche Bank AG109,273$586.8K0.00%+13,488+14.1%Added
XTX Topco Ltd115,634$621.0K0.02%+98,684+582.2%Added
Brevan Howard Capital Management LP118,528$636.5K0.01%+72,651+158.4%Added
Squarepoint Ops LLC126,192$677.7K0.00%+38,339+43.6%Added
Gsa Capital Partners LLP133,810$719.0K0.06%+133,810New
Rhumbline Advisers134,605$722.8K0.00%−4,708−3.4%Reduced
ADAR1 Capital Management, LLC139,000$746.4K0.06%+89,000+178.0%Added
Wells Fargo & Company144,798$777.6K0.00%+76,625+112.4%Added
Alps Advisors Inc146,040$784.2K0.00%+63,033+75.9%Added
Rafferty Asset Management, LLC151,743$814.9K0.00%+80,784+113.8%Added
AQR Capital Management LLC155,218$833.5K0.00%+96,070+162.4%Added
UBS Group AG167,856$901.4K0.00%−30,415−15.3%Reduced
State of Wisconsin Investment Board185,423$995.7K0.00%+144,023+347.9%Added
Connor, Clark & Lunn Investment Management Ltd.191,724$1.03M0.00%+191,724New
Boothbay Fund Management, LLC205,024$1.10M0.03%+205,024New
Arrowstreet Capital, Limited Partnership210,249$1.13M0.00%+210,249New
HighVista Strategies LLC245,532$1.32M0.34%+245,532New
Citigroup Inc261,876$1.41M0.00%+251,225+2,358.7%Added
Bank of America Corp266,434$1.43M0.00%+192,633+261.0%Added
Royce & Associates LP285,988$1.54M0.02%+285,988New
Nuveen, LLC288,924$1.55M0.00%+29,713+11.5%Added
Bank of New York Mellon Corp312,480$1.68M0.00%+89,304+40.0%Added
Prudential Financial Inc314,750$1.69M0.00%+314,750New
Wellington Management Group LLP316,849$1.70M0.00%−1,275−0.4%Reduced
Dimensional Fund Advisors LP341,596$1.83M0.00%+166,040+94.6%Added
Morgan Stanley365,245$1.96M0.00%+178,293+95.4%Added
Charles Schwab Investment Management Inc410,157$2.20M0.00%+74,907+22.3%Added
Qube Research & Technologies Ltd441,805$2.37M0.00%+441,805New
Schonfeld Strategic Advisors LLC452,442$2.43M0.01%−23,849−5.0%Reduced
Y-Intercept (Hong Kong) Ltd462,166$2.48M0.06%+462,166New
Seven Fleet Capital Management LP568,747$3.05M2.07%+568,747New
HealthInvest Partners AB584,332$3.14M1.00%+584,332New
Barclays PLC594,776$3.19M0.00%+372,358+167.4%Added
Burkehill Global Management, LP700,000$3.76M0.25%00.0%Unchanged
Ikarian Capital, LLC800,000$4.30M0.56%+800,000New
Ameriprise Financial Inc823,174$4.42M0.00%+823,174New
JPMorgan Chase & Co870,014$4.67M0.00%−1,129,264−56.5%Reduced
Northern Trust Corp972,935$5.22M0.00%+111,000+12.9%Added
Monashee Investment Management LLC1,000,000$5.37M3.03%−250,000−20.0%Reduced
Silverarc Capital Management, LLC1,051,343$5.65M0.82%−1,782,645−62.9%Reduced
Acuta Capital Partners, LLC1,093,300$5.87M3.99%+253,210+30.1%Added
NEXTBio Capital Management LP1,114,005$5.98M3.51%+1,114,005New
Logos Global Management LP1,150,000$6.18M0.41%−900,000−43.9%Reduced
Marshall Wace, LLP1,263,647$6.79M0.01%+1,263,647New
Trails Edge Capital Partners, LP1,415,273$7.60M1.88%+1,415,273New
Goldman Sachs Group Inc1,517,415$8.15M0.00%+477,744+46.0%Added
Birchview Capital, LP1,592,938$8.55M5.01%+720,000+82.5%Added
Balyasny Asset Management LLC1,593,275$8.56M0.02%−1,233,087−43.6%Reduced
RTW Investments, LP2,500,000$13.4M0.13%00.0%Unchanged
Palo Alto Investors LP2,532,419$13.6M1.89%+2,532,419New
FMR LLC2,579,711$13.9M0.00%−1,557,851−37.7%Reduced
Braidwell LP2,786,778$15.0M0.48%+2,786,778New
Millennium Management LLC3,109,286$16.7M0.01%−128,286−4.0%Reduced
Sofinnova Investments, Inc.3,365,446$18.1M0.78%+1,336,560+65.9%Added
Blue Owl Capital Holdings LP3,466,525$18.6M5.74%+875,000+33.8%Added
Geode Capital Management, LLC3,502,526$18.8M0.00%+558,057+19.0%Added
Deerfield Management Company, L.P. (Series C)3,606,000$19.4M0.25%+3,606,000New
Rock Springs Capital Management LP3,927,202$21.1M1.08%−547,500−12.2%Reduced
Adage Capital Partners GP, L.L.C.4,436,500$23.8M0.04%−750,000−14.5%Reduced
State Street Corp4,890,525$26.3M0.00%+1,784,012+57.4%Added
Blackstone Group Inc.6,126,182$32.9M0.14%−3,713,926−37.7%Reduced
BVF Inc7,764,842$41.7M1.40%+3,014,842+63.5%Added
Enavate Sciences GP, LLC7,788,150$41.8M8.25%00.0%Unchanged
Vanguard Group Inc8,048,374$43.2M0.00%+985,575+14.0%Added
BlackRock, Inc.9,388,624$50.4M0.00%+2,017,877+27.4%Added
Vivo Capital, LLC9,545,466$51.3M3.31%00.0%Unchanged
Suvretta Capital Management, LLC14,182,379$76.2M1.90%+81,220+0.6%Added
OrbiMed Advisors LLC15,219,994$81.7M1.67%00.0%Unchanged
Tang Capital Management LLC16,790,809$90.2M4.45%−21,154−0.1%Reduced
MPM Oncology Impact Management LP0$00.00%−5,075,970−100.0%Sold out
DAFNA Capital Management LLC0$00.00%−946,661−100.0%Sold out
Caption Management, LLC0$00.00%−154,170−100.0%Sold out
Cantor Fitzgerald, L. P.0$00.00%−80,000−100.0%Sold out
Renaissance Technologies LLC0$00.00%−79,000−100.0%Sold out
STRS Ohio0$00.00%−17,900−100.0%Sold out
Virtu Financial LLC0$00.00%−12,681−100.0%Sold out
ACT Advisors, LLC.0$00.00%−10,376−100.0%Sold out
Apollon Wealth Management, LLC0$00.00%−10,015−100.0%Sold out
Clearstead Advisors, LLC0$00.00%−4−100.0%Sold out
CIBC Bancorp USA Inc.––––Not filed