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Compass Therapeutics, Inc.

CMPX
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001738021

In the last 90 days, Compass Therapeutics, Inc. insiders filed 1 open-market purchase and 0 sales; 215 institutions reported holding it in 13F filings for Q2 2026, worth $363.4M in total; no superinvestor holds it.

Q4 2025 vs. Q3 2025

How the institutions holding Compass Therapeutics, Inc. changed between Q3 2025 and Q4 2025.

All holders in Q4 2025All holders in Q3 2025

13F holders of CMPX: Q3 2025 compared with Q4 2025
MeasureQ3 2025Of which not filed for Q4 2025Q4 2025Change
Holders1251173+49
Shares151.1M10.6K164.1M+13.1M (+8.7%)
Value$528.7M$37.1K$881.5M+$352.8M (+66.7%)

1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (59)

Institutions that held Compass Therapeutics, Inc. at the end of Q4 2025 but not at the end of Q3 2025.

Institutions new to CMPX in Q4 2025
InstitutionSharesValue% of portfolio
Deerfield Management Company, L.P. (Series C)3,606,000$19.4M0.25%
Braidwell LP2,786,778$15.0M0.48%
Palo Alto Investors LP2,532,419$13.6M1.89%
Trails Edge Capital Partners, LP1,415,273$7.60M1.88%
Marshall Wace, LLP1,263,647$6.79M0.01%
NEXTBio Capital Management LP1,114,005$5.98M3.51%
Ameriprise Financial Inc823,174$4.42M0.00%
Ikarian Capital, LLC800,000$4.30M0.56%
HealthInvest Partners AB584,332$3.14M1.00%
Seven Fleet Capital Management LP568,747$3.05M2.07%
Y-Intercept (Hong Kong) Ltd462,166$2.48M0.06%
Qube Research & Technologies Ltd441,805$2.37M0.00%
Prudential Financial Inc314,750$1.69M0.00%
Royce & Associates LP285,988$1.54M0.02%
HighVista Strategies LLC245,532$1.32M0.34%
Arrowstreet Capital, Limited Partnership210,249$1.13M0.00%
Boothbay Fund Management, LLC205,024$1.10M0.03%
Connor, Clark & Lunn Investment Management Ltd.191,724$1.03M0.00%
Gsa Capital Partners LLP133,810$719.0K0.06%
NEOS Investment Management LLC101,676$546.0K0.00%
Tema ETFs LLC100,176$537.9K0.04%
SummitTX Capital, L.P.81,449$437.4K0.01%
Raymond James Financial Inc80,142$430.4K0.00%
Franklin Resources Inc66,607$357.7K0.00%
Persistent Asset Partners Ltd57,253$307.4K0.15%
Graham Capital Management, L.P.53,427$286.9K0.01%
Virtus Investment Advisers, Inc.51,556$276.9K0.08%
D. E. Shaw & Co., Inc.51,482$276.5K0.00%
Axq Capital, LP41,378$222.2K0.05%
American Century Companies Inc40,412$217.0K0.00%
SmartHarvest Portfolios, LLC34,715$186.4K0.06%
Avanza Fonder AB27,347$146.9K0.00%
Caitong International Asset Management Co., Ltd24,579$132.0K0.03%
DV Trading LLC24,207$130.0K0.01%
Stifel Financial Corp23,973$128.7K0.00%
Abel Hall, LLC22,882$122.9K0.03%
Independent Financial Group, LLC22,779$122.3K0.00%
Two Sigma Advisers, LP15,200$81.6K0.00%
Canada Pension Plan Investment Board14,900$80.0K0.00%
M&T Bank Corp14,894$80.0K0.00%
EntryPoint Capital, LLC13,163$70.7K0.03%
Neuberger Berman Group LLC12,807$68.8K0.00%
Xponance, Inc.10,201$54.8K0.00%
Cygnus Capital Advisors, LLC10,000$54.0K0.04%
Prelude Capital Management, LLC10,000$53.7K0.00%
Flagship Harbor Advisors, LLC6,000$32.2K0.00%
Group One Trading, L.P.5,244$28.2K0.00%
Acadian Asset Management LLC4,867$26.0K0.00%
VSM Wealth Advisory, LLC3,000$16.1K0.00%
Rockefeller Capital Management L.P.2,042$11.0K0.00%
Federation des caisses Desjardins du Quebec500$2.69K0.00%
National Bank of Canada242$1.30K0.00%
Smartleaf Asset Management LLC69$3710.00%
Advisor Group Holdings, Inc.57$3060.00%
CIBC Private Wealth Group, LLC38$2040.00%
GAMMA Investing LLC29$1560.00%
SJS Investment Consulting Inc.27$1450.00%
MAI Capital Management24$1290.00%
Hughes Financial Services, LLC1$50.00%

Sold out (10)

Institutions that held Compass Therapeutics, Inc. at the end of Q3 2025 and filed for Q4 2025 without it.

Institutions that sold out of CMPX in Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
MPM Oncology Impact Management LP5,075,970$17.8M
DAFNA Capital Management LLC946,661$3.31M
Caption Management, LLC154,170$539.6K
Cantor Fitzgerald, L. P.80,000$280.0K
Renaissance Technologies LLC79,000$276.5K
STRS Ohio17,900$62.6K
Virtu Financial LLC12,681$44.0K
ACT Advisors, LLC.10,376$36.3K
Apollon Wealth Management, LLC10,015$35.1K
Clearstead Advisors, LLC4$14

Not filed for Q4 2025 yet (1)

Institutions that held Compass Therapeutics, Inc. at the end of Q3 2025 and haven't filed a 13F for Q4 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding CMPX in Q3 2025 that haven't filed for Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
CIBC Bancorp USA Inc.10,600$37.1K