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Compass Therapeutics, Inc.

CMPX
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001738021

In the last 90 days, Compass Therapeutics, Inc. insiders filed 1 open-market purchase and 0 sales; 215 institutions reported holding it in 13F filings for Q2 2026, worth $363.4M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Compass Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
173
+49 vs. Q3 2025
Shares held
164.1M
+13.1M (+8.7%) vs. Q3 2025
Total value
$881.5M
+$352.8M (+66.7%) vs. Q3 2025
New holders
59
60 more added
Sold out
10
34 more reduced

1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CMPX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 173 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 37 institutionsQ1 2022: 34 institutionsQ2 2022: 34 institutionsQ3 2022: 38 institutionsQ4 2022: 55 institutionsQ1 2023: 73 institutionsQ2 2023: 73 institutionsQ3 2023: 76 institutionsQ4 2023: 77 institutionsQ1 2024: 78 institutionsQ2 2024: 82 institutionsQ3 2024: 79 institutionsQ4 2024: 92 institutionsQ1 2025: 108 institutionsQ2 2025: 103 institutionsQ3 2025: 125 institutionsQ4 2025: 173 institutionsQ1 2026: 201 institutionsQ2 2026: 215 institutions
Value heldQ4 2025: $881.5M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $201.6MQ1 2022: $85.4MQ2 2022: $163.9MQ3 2022: $145.6MQ4 2022: $401.4MQ1 2023: $266.5MQ2 2023: $287.7MQ3 2023: $176.7MQ4 2023: $134.3MQ1 2024: $187.2MQ2 2024: $93.4MQ3 2024: $169.6MQ4 2024: $147.0MQ1 2025: $206.1MQ2 2025: $281.5MQ3 2025: $528.7MQ4 2025: $881.5MQ1 2026: $921.3MQ2 2026: $363.4M
Institutions holding CMPX and their total value by quarter
QuarterHoldersValue
Q2 2026215$363.4M
Q1 2026201$921.3M
Q4 2025173$881.5M
Q3 2025125$528.7M
Q2 2025103$281.5M
Q1 2025108$206.1M
Q4 202492$147.0M
Q3 202479$169.6M
Q2 202482$93.4M
Q1 202478$187.2M
Q4 202377$134.3M
Q3 202376$176.7M
Q2 202373$287.7M
Q1 202373$266.5M
Q4 202255$401.4M
Q3 202238$145.6M
Q2 202234$163.9M
Q1 202234$85.4M
Q4 202137$201.6M
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Compass Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding CMPX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Hughes Financial Services, LLC1$50.00%+1New
IFP Advisors, Inc6$320.00%00.0%Unchanged
Sunbelt Securities, Inc.8$430.00%00.0%Unchanged
Essential Partners LLC9$480.00%−10−52.6%Reduced
SRS Capital Advisors, Inc.18$970.00%−207−92.0%Reduced
Allworth Financial LP20$1080.00%+16+400.0%Added
MAI Capital Management24$1290.00%+24New
SJS Investment Consulting Inc.27$1450.00%+27New
GAMMA Investing LLC29$1560.00%+29New
CIBC Private Wealth Group, LLC38$2040.00%+38New
Advisor Group Holdings, Inc.57$3060.00%+57New
Smartleaf Asset Management LLC69$3710.00%+69New
Rothschild Investment LLC164$8810.00%+44+36.7%Added
Marshall & Sterling Wealth Advisors Inc.200$1.07K0.00%00.0%Unchanged
SBI Securities Co., Ltd.237$1.27K0.00%−93−28.2%Reduced
National Bank of Canada242$1.30K0.00%+242New
Quadrant Capital Group LLC405$2.17K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.413$2.22K0.00%−5,409−92.9%Reduced
Federation des caisses Desjardins du Quebec500$2.69K0.00%+500New
Bessemer Group Inc526$3.00K0.00%00.0%Unchanged
Farther Finance Advisors, LLC680$3.65K0.00%+292+75.3%Added
Optiver Holding B.V.1,096$5.89K0.00%−546−33.3%Reduced
Tower Research Capital LLC (TRC)1,698$9.12K0.00%−4,341−71.9%Reduced
Cape Investment Advisory, Inc.2,002$10.8K0.00%+685+52.0%Added
Rockefeller Capital Management L.P.2,042$11.0K0.00%+2,042New
CWM, LLC3,059$16.0K0.00%+1,168+61.8%Added
VSM Wealth Advisory, LLC3,000$16.1K0.00%+3,000New
Sterling Capital Management LLC3,827$20.6K0.00%+492+14.8%Added
Royal Bank of Canada3,821$21.0K0.00%−1,697,106−99.8%Reduced
Amalgamated Bank4,111$22.0K0.00%+1,034+33.6%Added
EverSource Wealth Advisors, LLC4,370$23.5K0.00%−1,859−29.8%Reduced
Fortitude Family Office, LLC4,591$24.7K0.01%−387−7.8%Reduced
Acadian Asset Management LLC4,867$26.0K0.00%+4,867New
Group One Trading, L.P.5,244$28.2K0.00%+5,244New
Nisa Investment Advisors, LLC5,248$28.2K0.00%00.0%Unchanged
MCF Advisors LLC5,540$29.8K0.00%00.0%Unchanged
Flagship Harbor Advisors, LLC6,000$32.2K0.00%+6,000New
California State Teachers Retirement System8,056$43.3K0.00%+662+9.0%Added
Simplex Trading, LLC8,912$47.9K0.00%+4,819+117.7%Added
Prelude Capital Management, LLC10,000$53.7K0.00%+10,000New
Cygnus Capital Advisors, LLC10,000$54.0K0.04%+10,000New
Xponance, Inc.10,201$54.8K0.00%+10,201New
Stonebrook Private Inc.10,230$54.9K0.01%00.0%Unchanged
Ameritas Investment Partners, Inc.10,621$57.0K0.00%+3,085+40.9%Added
Russell Investments Group, Ltd.11,558$62.1K0.00%+3,773+48.5%Added
Strategic Wealth Partners, Ltd.12,100$65.0K0.00%00.0%Unchanged
Quadrature Capital Ltd12,293$66.0K0.00%−35,134−74.1%Reduced
North Star Investment Management Corp.12,500$67.1K0.00%00.0%Unchanged
Legal & General Group Plc12,753$68.5K0.00%+3,110+32.3%Added
Neuberger Berman Group LLC12,807$68.8K0.00%+12,807New
EntryPoint Capital, LLC13,163$70.7K0.03%+13,163New
Financial Advisory Corp13,495$72.0K0.02%00.0%Unchanged
Victory Capital Management Inc14,311$76.8K0.00%+1,659+13.1%Added
M&T Bank Corp14,894$80.0K0.00%+14,894New
Canada Pension Plan Investment Board14,900$80.0K0.00%+14,900New
Two Sigma Advisers, LP15,200$81.6K0.00%+15,200New
BNP Paribas Arbitrage, SA15,645$84.0K0.00%−3,878−19.9%Reduced
Sequoia Financial Advisors, LLC15,894$85.4K0.00%+141+0.9%Added
Sig Brokerage, LP17,076$91.7K0.03%−9,289−35.2%Reduced
Independent Advisor Alliance17,894$96.1K0.00%00.0%Unchanged
Colony Group, LLC18,595$99.9K0.00%+2,790+17.7%Added
Welch & Forbes LLC19,000$102.0K0.00%+4,000+26.7%Added
Captrust Financial Advisors20,846$111.9K0.00%+322+1.6%Added
Voya Investment Management LLC22,629$121.5K0.00%+5,415+31.5%Added
Independent Financial Group, LLC22,779$122.3K0.00%+22,779New
Abel Hall, LLC22,882$122.9K0.03%+22,882New
ProShare Advisors LLC23,972$128.7K0.00%+6,968+41.0%Added
Stifel Financial Corp23,973$128.7K0.00%+23,973New
DV Trading LLC24,207$130.0K0.01%+24,207New
Caitong International Asset Management Co., Ltd24,579$132.0K0.03%+24,579New
Walleye Trading LLC25,000$134.3K0.00%00.0%Unchanged
Avanza Fonder AB27,347$146.9K0.00%+27,347New
Caxton Corp29,495$158.4K3.70%−24,008−44.9%Reduced
New York State Common Retirement Fund30,407$163.3K0.00%00.0%Unchanged
Simplicity Wealth,LLC33,869$181.9K0.01%−3,165−8.5%Reduced
SmartHarvest Portfolios, LLC34,715$186.4K0.06%+34,715New
Police & Firemen's Retirement System of New Jersey35,503$190.7K0.00%+7,172+25.3%Added
Intech Investment Management LLC38,936$209.1K0.00%00.0%Unchanged
Manufacturers Life Insurance Company, The40,325$216.5K0.00%+7,164+21.6%Added
American Century Companies Inc40,412$217.0K0.00%+40,412New
Axq Capital, LP41,378$222.2K0.05%+41,378New
LPL Financial LLC44,470$238.8K0.00%+2,000+4.7%Added
Susquehanna International Group, LLP44,742$240.3K0.00%+24,782+124.2%Added
D. E. Shaw & Co., Inc.51,482$276.5K0.00%+51,482New
Virtus Investment Advisers, Inc.51,556$276.9K0.08%+51,556New
Graham Capital Management, L.P.53,427$286.9K0.01%+53,427New
Profund Advisors LLC57,246$307.4K0.01%+40,778+247.6%Added
Persistent Asset Partners Ltd57,253$307.4K0.15%+57,253New
Invesco Ltd.63,901$343.1K0.00%+3,245+5.3%Added
Franklin Resources Inc66,607$357.7K0.00%+66,607New
Mirae Asset Global ETFs Holdings Ltd.69,576$373.7K0.00%+19,726+39.6%Added
Jane Street Group, LLC70,063$376.2K0.00%+38,384+121.2%Added
Price T Rowe Associates Inc70,488$379.0K0.00%+13,900+24.6%Added
MetLife Investment Management73,985$397.3K0.00%+15,638+26.8%Added
Atom Investors LP77,281$415.0K0.03%−29,393−27.6%Reduced
Raymond James Financial Inc80,142$430.4K0.00%+80,142New
SummitTX Capital, L.P.81,449$437.4K0.01%+81,449New
Alliancebernstein L.P.83,940$450.8K0.00%−20,220−19.4%Reduced
CM Management, LLC100,000$537.0K0.45%−50,000−33.3%Reduced
Tema ETFs LLC100,176$537.9K0.04%+100,176New