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Caris Life Sciences, Inc.

CAI
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0002019410

In the last 90 days, Caris Life Sciences, Inc. insiders filed 1 open-market purchase and 3 sales; 247 institutions reported holding it in 13F filings for Q2 2026, worth $2.75B in total; superinvestors Coatue Management and Duquesne Family Office hold it.

13F holders, Q2 2026

Institutional positions in Caris Life Sciences, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
247
+46 vs. Q1 2026
Shares held
154.3M
−2.52M (−1.6%) vs. Q1 2026
Total value
$2.75B
−$47.9M (−1.7%) vs. Q1 2026
New holders
70
105 more added
Sold out
24
47 more reduced

1 institution that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CAI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 247 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 0 institutionsQ2 2025: 116 institutionsQ3 2025: 138 institutionsQ4 2025: 186 institutionsQ1 2026: 202 institutionsQ2 2026: 247 institutions
Value heldQ2 2026: $2.75B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $0Q2 2025: $2.92BQ3 2025: $3.41BQ4 2025: $3.92BQ1 2026: $2.80BQ2 2026: $2.75B
Institutions holding CAI and their total value by quarter
QuarterHoldersValue
Q2 2026247$2.75B
Q1 2026202$2.80B
Q4 2025186$3.92B
Q3 2025138$3.41B
Q2 2025116$2.92B
Q1 20250$0
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Caris Life Sciences, Inc.; share changes are against Q1 2026.

Institutions holding CAI in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Menlo Advisors LLC300,518$5.36M2.35%+300,518New
Bank of New York Mellon Corp308,407$5.50M0.00%+76,746+33.1%Added
TD Asset Management Inc379,388$6.76M0.01%−291,000−43.4%Reduced
Squarepoint Ops LLC380,927$6.79M0.01%+380,927New
Walleye Capital LLC424,407$7.56M0.04%+424,407New
Quantinno Capital Management LP441,672$7.87M0.01%+300,763+213.4%Added
Rock Springs Capital Management LP487,500$8.69M0.42%−75,500−13.4%Reduced
Renaissance Technologies LLC568,000$10.1M0.01%+118,100+26.3%Added
Ameriprise Financial Inc572,784$10.2M0.00%+164,705+40.4%Added
Nuveen, LLC604,416$10.8M0.00%−59,162−8.9%Reduced
Arrowstreet Capital, Limited Partnership655,644$11.7M0.01%+445,051+211.3%Added
Woodline Partners LP723,163$12.9M0.04%00.0%Unchanged
Trexquant Investment LP727,944$13.0M0.08%+237,408+48.4%Added
SEI Investments Co762,659$13.6M0.01%+163,947+27.4%Added
Zevenbergen Capital Investments LLC802,083$14.3M0.33%+191,850+31.4%Added
Goldman Sachs Group Inc951,942$17.0M0.00%+541,602+132.0%Added
Geode Capital Management, LLC1,044,657$18.6M0.00%+266,125+34.2%Added
Champlain Investment Partners, LLC1,048,862$18.7M0.48%−159,101−13.2%Reduced
Bank of America Corp1,200,590$21.4M0.00%+677,322+129.4%Added
Price T Rowe Associates Inc1,205,390$21.5M0.00%−3,166,381−72.4%Reduced
Capital World Investors1,213,272$21.6M0.00%+33,099+2.8%Added
Amundi1,218,364$21.7M0.01%+1,197,392+5,709.5%Added
State Street Corp1,217,548$21.7M0.00%+232,595+23.6%Added
Canada Pension Plan Investment Board1,374,952$24.5M0.01%+52,200+3.9%Added
HRT Financial LP1,418,392$25.3M0.05%+1,418,392New
UBS Group AG1,423,371$25.4M0.00%−1,322,440−48.2%Reduced
FIL Ltd1,548,918$27.6M0.02%+2,827+0.2%Added
Clearbridge Investments, LLC1,595,877$28.4M0.02%+44,103+2.8%Added
Duquesne Family Office LLCSuperinvestorDuquesne Family Office1,894,450$33.8M0.78%00.0%Unchanged
Morgan Stanley1,935,531$34.5M0.00%+856,114+79.3%Added
Mak Capital One LLC1,937,229$34.5M4.84%+1,937,229New
Millennium Management LLC2,202,647$39.3M0.03%+674,891+44.2%Added
BNP Paribas Arbitrage, SA2,370,268$42.2M0.02%+755,982+46.8%Added
OrbiMed Advisors LLC2,806,811$50.0M0.95%00.0%Unchanged
Neuberger Berman Group LLC3,590,963$64.0M0.04%+3770.0%Added
Los Angeles Capital Management LLC3,958,531$70.5M0.26%+1,668,929+72.9%Added
Vanguard Capital Management LLC4,280,238$76.3M0.00%+951,217+28.6%Added
Vanguard Portfolio Management LLC4,844,431$86.3M0.00%+1,085,969+28.9%Added
T. Rowe Price Investment Management, Inc.5,079,141$90.5M0.06%−509,116−9.1%Reduced
BlackRock, Inc.5,536,798$98.7M0.00%+679,686+14.0%Added
JPMorgan Chase & Co6,558,514$120.2M0.01%+3,098,299+89.5%Added
PointState Capital LP6,828,835$121.7M2.14%−531,611−7.2%Reduced
Sixth Street Partners Management Company, L.P.7,327,041$130.6M22.54%−7,058,358−49.1%Reduced
Braidwell LP8,256,032$147.1M5.44%+246,585+3.1%Added
Coatue Management LLCSuperinvestorCoatue Management9,819,992$175.0M0.36%00.0%Unchanged
J. H. Whitney Equity Partners VI, LLC11,256,615$200.6M100.00%−7,000,000−38.3%Reduced
FMR LLC30,923,878$551.1M0.02%+138,293+0.4%Added
Point72 Asset Management, L.P.0$00.00%−918,331−100.0%Sold out
Parkman Healthcare Partners LLC0$00.00%−229,912−100.0%Sold out
Man Group plc0$00.00%−128,971−100.0%Sold out
Oddo BHF Asset Management SAS0$00.00%−109,539−100.0%Sold out
Engineers Gate Manager LP0$00.00%−102,757−100.0%Sold out
Burkehill Global Management, LP0$00.00%−75,000−100.0%Sold out
Twinbeech Capital LP0$00.00%−58,100−100.0%Sold out
Franklin Resources Inc0$00.00%−44,975−100.0%Sold out
Axq Capital, LP0$00.00%−22,125−100.0%Sold out
Perbak Capital Partners LLP0$00.00%−22,001−100.0%Sold out
Verition Fund Management LLC0$00.00%−20,000−100.0%Sold out
HSBC Holdings PLC0$00.00%−16,494−100.0%Sold out
Savant Capital, LLC0$00.00%−13,803−100.0%Sold out
ProShare Advisors LLC0$00.00%−12,622−100.0%Sold out
Jacobs Levy Equity Management, Inc0$00.00%−12,340−100.0%Sold out
Bessemer Group Inc0$00.00%−11,880−100.0%Sold out
Wedmont Private Capital0$00.00%−10,715−100.0%Sold out
Jefferies Financial Group Inc.0$00.00%−10,745−100.0%Sold out
Quadrant Capital Group LLC0$00.00%−2,884−100.0%Sold out
Ancora Advisors, LLC0$00.00%−1,923−100.0%Sold out
MAI Capital Management0$00.00%−1,035−100.0%Sold out
CX Institutional0$00.00%−684−100.0%Sold out
Advisory Services Network, LLC0$00.00%−100−100.0%Sold out
Wealth Preservation Advisors, LLC0$00.00%−3−100.0%Sold out
CWM, LLC––––Not filed