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Caris Life Sciences, Inc.

CAI
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0002019410

In the last 90 days, Caris Life Sciences, Inc. insiders filed 1 open-market purchase and 3 sales; 247 institutions reported holding it in 13F filings for Q2 2026, worth $2.75B in total; superinvestors Coatue Management and Duquesne Family Office hold it.

13F holders, Q1 2026

Institutional positions in Caris Life Sciences, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
202
+22 vs. Q4 2025
Shares held
156.9M
+11.7M (+8.1%) vs. Q4 2025
Total value
$2.80B
−$1.11B (−28.4%) vs. Q4 2025
New holders
57
88 more added
Sold out
35
38 more reduced

6 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CAI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 202 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 0 institutionsQ2 2025: 116 institutionsQ3 2025: 138 institutionsQ4 2025: 186 institutionsQ1 2026: 202 institutionsQ2 2026: 247 institutions
Value heldQ1 2026: $2.80B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $0Q2 2025: $2.92BQ3 2025: $3.41BQ4 2025: $3.92BQ1 2026: $2.80BQ2 2026: $2.75B
Institutions holding CAI and their total value by quarter
QuarterHoldersValue
Q2 2026247$2.75B
Q1 2026202$2.80B
Q4 2025186$3.92B
Q3 2025138$3.41B
Q2 2025116$2.92B
Q1 20250$0
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Caris Life Sciences, Inc.; share changes are against Q4 2025.

Institutions holding CAI in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
J. H. Whitney Equity Partners VI, LLC18,256,615$326.4M100.00%−2,000,000−9.9%Reduced
FMR LLC30,785,585$550.4M0.03%+16,567,817+116.5%Added
Balyasny Asset Management LLC0$00.00%−1,660,280−100.0%Sold out
Longaeva Partners L.P.0$00.00%−1,509,745−100.0%Sold out
Perceptive Advisors LLC0$00.00%−1,136,206−100.0%Sold out
Marshall Wace, LLP0$00.00%−1,002,734−100.0%Sold out
Seven Grand Managers, LLC0$00.00%−495,095−100.0%Sold out
ARK Investment Management LLCSuperinvestorARK Invest0$00.00%−408,725−100.0%Sold out
Meridiem Capital Partners LP0$00.00%−278,063−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−247,407−100.0%Sold out
Holocene Advisors, LP0$00.00%−237,897−100.0%Sold out
Jane Street Group, LLC0$00.00%−170,997−100.0%Sold out
Walleye Capital LLC0$00.00%−162,915−100.0%Sold out
HRT Financial LP0$00.00%−122,939−100.0%Sold out
Jump Financial, LLC0$00.00%−103,005−100.0%Sold out
Squarepoint Ops LLC0$00.00%−64,397−100.0%Sold out
Hamilton Lane Advisors LLC0$00.00%−58,725−100.0%Sold out
Element Capital Management LLC0$00.00%−50,000−100.0%Sold out
Mangrove Partners0$00.00%−42,483−100.0%Sold out
VARCOV Co.0$00.00%−40,037−100.0%Sold out
Maven Securities LTD0$00.00%−40,000−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−35,050−100.0%Sold out
PEAK6 LLC0$00.00%−24,800−100.0%Sold out
Magnetar Financial LLC0$00.00%−17,493−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−16,490−100.0%Sold out
Davy Global Fund Management Ltd0$00.00%−15,546−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−15,235−100.0%Sold out
Lighthouse Investment Partners, LLC0$00.00%−13,251−100.0%Sold out
Clal Insurance Enterprises Holdings Ltd0$00.00%−11,930−100.0%Sold out
Lykos Global Management, LP0$00.00%−10,000−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−9,767−100.0%Sold out
Occudo Quantitative Strategies LP0$00.00%−8,355−100.0%Sold out
Adams Street Partners LLC0$00.00%−4,894−100.0%Sold out
Aster Capital Management (DIFC) Ltd0$00.00%−2,488−100.0%Sold out
Amalgamated Bank0$00.00%−1,471−100.0%Sold out
Daiwa Securities Group Inc.0$00.00%−850−100.0%Sold out
SageView Advisory Group, LLC0$00.00%−32−100.0%Sold out
Norges Bank––––Not filed
Vanguard Group Inc––––Not filed
Sandia Investment Management LP––––Not filed
Global Retirement Partners, LLC––––Not filed
Comerica Bank––––Not filed
Trust Co of Vermont––––Not filed