Cabaletta Bio, Inc.
CABA- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001759138
No open-market purchases or sales by Cabaletta Bio, Inc. insiders were filed in the last 90 days; 139 institutions reported holding it in 13F filings for Q2 2026, worth $490.4M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Cabaletta Bio, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 95
- +22 vs. Q3 2025
- Shares held
- 76.2M
- +7.08M (+10.2%) vs. Q3 2025
- Total value
- $166.9M
- +$5.07M (+3.1%) vs. Q3 2025
- New holders
- 30
- 33 more added
- Sold out
- 8
- 18 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CABA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 139 | $490.4M |
| Q1 2026 | 108 | $227.5M |
| Q4 2025 | 95 | $166.9M |
| Q3 2025 | 75 | $162.0M |
| Q2 2025 | 86 | $110.7M |
| Q1 2025 | 93 | $50.3M |
| Q4 2024 | 109 | $87.2M |
| Q3 2024 | 120 | $226.7M |
| Q2 2024 | 142 | $380.0M |
| Q1 2024 | 159 | $870.9M |
| Q4 2023 | 128 | $1.10B |
| Q3 2023 | 97 | $622.6M |
| Q2 2023 | 84 | $470.5M |
| Q1 2023 | 72 | $203.9M |
| Q4 2022 | 61 | $183.9M |
| Q3 2022 | 54 | $7.76M |
| Q2 2022 | 55 | $17.8M |
| Q1 2022 | 62 | $36.9M |
| Q4 2021 | 66 | $68.9M |
| Q3 2021 | 61 | $211.3M |
| Q2 2021 | 63 | $135.5M |
| Q1 2021 | 68 | $180.1M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Cabaletta Bio, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| T. Rowe Price Investment Management, Inc. | 9,858,257 | $21.6M | 0.01% | +1,495,768+17.9% | Added |
| Bain Capital Life Sciences Investors, LLC | 9,677,125 | $21.2M | 1.62% | 00.0% | Unchanged |
| Jennison Associates LLC | 8,905,699 | $19.5M | 0.01% | +408,162+4.8% | Added |
| Adage Capital Partners GP, L.L.C. | 8,829,758 | $19.3M | 0.03% | 00.0% | Unchanged |
| Vanguard Group Inc | 4,419,458 | $9.68M | 0.00% | +228,699+5.5% | Added |
| Cormorant Asset Management, LP | 4,400,000 | $9.64M | 0.55% | −600,000−12.0% | Reduced |
| Millennium Management LLC | 2,736,912 | $5.99M | 0.00% | +2,050,099+298.5% | Added |
| BlackRock, Inc. | 2,328,470 | $5.10M | 0.00% | +707,598+43.7% | Added |
| Superstring Capital Management LP | 2,253,550 | $4.94M | 2.64% | +709,025+45.9% | Added |
| Two Sigma Investments, LP | 1,839,799 | $4.03M | 0.01% | +1,369,324+291.1% | Added |
| Renaissance Technologies LLC | 1,522,583 | $3.33M | 0.01% | +183,160+13.7% | Added |
| Morgan Stanley | 1,343,708 | $2.94M | 0.00% | −130,968−8.9% | Reduced |
| Woodline Partners LP | 1,250,242 | $2.74M | 0.01% | −885,106−41.5% | Reduced |
| Schonfeld Strategic Advisors LLC | 1,204,070 | $2.64M | 0.01% | +159,901+15.3% | Added |
| Price T Rowe Associates Inc | 1,093,959 | $2.40M | 0.00% | −200,990−15.5% | Reduced |
| Geode Capital Management, LLC | 1,085,816 | $2.38M | 0.00% | +165,476+18.0% | Added |
| Marshall Wace, LLP | 959,076 | $2.10M | 0.00% | −366,967−27.7% | Reduced |
| Opaleye Management Inc. | 900,000 | $1.97M | 0.26% | +91,118+11.3% | Added |
| Ikarian Capital, LLC | 900,000 | $1.97M | 0.26% | +900,000 | New |
| Schroder Investment Management Group | 756,637 | $1.63M | 0.00% | +756,637 | New |
| Two Sigma Advisers, LP | 737,900 | $1.62M | 0.00% | +406,900+122.9% | Added |
| Burkehill Global Management, LP | 700,000 | $1.53M | 0.10% | 00.0% | Unchanged |
| Jane Street Group, LLC | 662,149 | $1.45M | 0.00% | +557,487+532.7% | Added |
| Ensign Peak Advisors, Inc | 550,000 | $1.20M | 0.00% | +550,000 | New |
| KVP Capital Advisors, LP | 505,431 | $1.11M | 1.14% | +505,431 | New |
| Dimensional Fund Advisors LP | 452,039 | $990.0K | 0.00% | +452,039 | New |
| Raiffeisen Bank International AG | 450,000 | $967.5K | 0.01% | +100,000+28.6% | Added |
| Goldman Sachs Group Inc | 430,674 | $943.2K | 0.00% | +158,078+58.0% | Added |
| State Street Corp | 425,478 | $931.8K | 0.00% | +48,678+12.9% | Added |
| UBS Group AG | 415,677 | $910.3K | 0.00% | +10,557+2.6% | Added |
| 683 Capital Management, LLC | 388,562 | $851.0K | 0.07% | +388,562 | New |
| Almitas Capital LLC | 387,491 | $848.6K | 0.19% | 00.0% | Unchanged |
| Qube Research & Technologies Ltd | 331,225 | $725.4K | 0.00% | +242,068+271.5% | Added |
| Gsa Capital Partners LLP | 303,992 | $666.0K | 0.06% | +303,992 | New |
| Boothbay Fund Management, LLC | 243,445 | $533.1K | 0.01% | +243,445 | New |
| Northern Trust Corp | 238,442 | $522.2K | 0.00% | +11,455+5.0% | Added |
| Barclays PLC | 220,696 | $483.3K | 0.00% | +217,613+7,058.5% | Added |
| Invesco Ltd. | 189,195 | $414.3K | 0.00% | +66,395+54.1% | Added |
| Stonepine Capital Management, LLC | 171,100 | $374.7K | 0.30% | +171,100 | New |
| XTX Topco Ltd | 155,387 | $340.3K | 0.01% | −128,912−45.3% | Reduced |
| Graham Capital Management, L.P. | 151,451 | $331.7K | 0.01% | +151,451 | New |
| Squarepoint Ops LLC | 149,094 | $326.5K | 0.00% | +137,226+1,156.3% | Added |
| Hudson Bay Capital Management LP | 138,729 | $303.8K | 0.00% | +138,729 | New |
| Susquehanna International Group, LLP | 138,281 | $302.8K | 0.00% | −233,827−62.8% | Reduced |
| Bridgeway Capital Management, LLC | 130,675 | $286.2K | 0.01% | +35,000+36.6% | Added |
| Omers Administration Corp | 95,400 | $208.9K | 0.00% | +95,400 | New |
| Letko, Brosseau & Associates Inc | 90,475 | $198.1K | 0.00% | +90,475 | New |
| TD Asset Management Inc | 88,600 | $194.0K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 73,774 | $161.6K | 0.00% | +73,422+20,858.5% | Added |
| Dynamic Technology Lab Private Ltd | 66,789 | $146.0K | 0.03% | +66,789 | New |
| Quadrature Capital Ltd | 66,377 | $145.4K | 0.00% | +23,465+54.7% | Added |
| American Century Companies Inc | 58,777 | $128.7K | 0.00% | +46,745+388.5% | Added |
| Point72 Asset Management, L.P. | 56,648 | $124.1K | 0.00% | +56,648 | New |
| Matauro, LLC | 55,108 | $120.7K | 0.02% | +55,108 | New |
| Bank of New York Mellon Corp | 54,047 | $118.4K | 0.00% | +6,237+13.0% | Added |
| Balyasny Asset Management LLC | 51,552 | $112.9K | 0.00% | +51,552 | New |
| Charles Schwab Investment Management Inc | 50,824 | $111.3K | 0.00% | 00.0% | Unchanged |
| Jefferies Financial Group Inc. | 45,125 | $98.8K | 0.00% | −2,375−5.0% | Reduced |
| LPL Financial LLC | 42,615 | $93.3K | 0.00% | +42,615 | New |
| Lighthouse Investment Partners, LLC | 38,880 | $85.1K | 0.00% | +38,880 | New |
| Citadel Advisors LLC | 33,502 | $73.4K | 0.00% | −671,963−95.3% | Reduced |
| SG Americas Securities, LLC | 30,629 | $67.0K | 0.00% | +9,365+44.0% | Added |
| Tower Research Capital LLC (TRC) | 30,345 | $66.5K | 0.00% | +25,978+594.9% | Added |
| Fred Alger Management, LLC | 28,021 | $61.4K | 0.00% | −31,792−53.2% | Reduced |
| Mercer Global Advisors Inc | 26,510 | $58.1K | 0.00% | +26,510 | New |
| Callan Family Office, LLC | 22,575 | $49.4K | 0.00% | +22,575 | New |
| JustInvest LLC | 22,384 | $49.0K | 0.00% | +233+1.1% | Added |
| Jones Financial Companies LLLP | 20,660 | $45.2K | 0.00% | +653+3.3% | Added |
| Clear Harbor Asset Management, LLC | 19,500 | $42.7K | 0.00% | +19,500 | New |
| Antipodes Partners Ltd | 17,187 | $37.6K | 0.00% | +17,187 | New |
| China Universal Asset Management Co., Ltd. | 15,686 | $34.4K | 0.00% | +15,686 | New |
| CRA Financial Services, LLC | 15,000 | $32.9K | 0.00% | 00.0% | Unchanged |
| Private Advisor Group, LLC | 14,725 | $32.2K | 0.00% | +14,725 | New |
| Bank of America Corp | 14,392 | $31.5K | 0.00% | −253,666−94.6% | Reduced |
| FMR LLC | 13,045 | $28.6K | 0.00% | −1,019−7.2% | Reduced |
| Manufacturers Life Insurance Company, The | 13,011 | $28.0K | 0.00% | −73−0.6% | Reduced |
| HB Wealth Management, LLC | 10,000 | $21.9K | 0.00% | +10,000 | New |
| JPMorgan Chase & Co | 9,805 | $21.5K | 0.00% | −527,844−98.2% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 4,678 | $10.2K | 0.00% | +4,678 | New |
| The PNC Financial Services Group, Inc. | 4,600 | $10.1K | 0.00% | +4,000+666.7% | Added |
| Canada Pension Plan Investment Board | 3,500 | $7.67K | 0.00% | +3,500 | New |
| Wells Fargo & Company | 2,000 | $4.38K | 0.00% | −1,000−33.3% | Reduced |
| GF Fund Management Co. Ltd. | 1,891 | $4.14K | 0.00% | +1,891 | New |
| BNP Paribas Arbitrage, SA | 1,640 | $3.59K | 0.00% | −191−10.4% | Reduced |
| Flagship Harbor Advisors, LLC | 1,000 | $2.19K | 0.00% | +1,000 | New |
| Russell Investments Group, Ltd. | 939 | $2.06K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 811 | $1.78K | 0.00% | 00.0% | Unchanged |
| Truvestments Capital LLC | 680 | $1.49K | 0.00% | 00.0% | Unchanged |
| Federation des caisses Desjardins du Quebec | 340 | $745 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 316 | $692 | 0.00% | −140−30.7% | Reduced |
| Northwestern Mutual Wealth Management Co | 60 | $131 | 0.00% | +58+2,900.0% | Added |
| Optiver Holding B.V. | 24 | $53 | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 10 | $22 | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 123 | $0 | 0.00% | −91,600−99.9% | Reduced |
| Covestor Ltd | 34 | $0 | 0.00% | 00.0% | Unchanged |
| Heights Capital Management, Inc | 0 | $0 | 0.00% | −2,084,202−100.0% | Sold out |
| Alyeska Investment Group, L.P. | 0 | $0 | 0.00% | −1,300,000−100.0% | Sold out |
| Acadian Asset Management LLC | 0 | $0 | 0.00% | −186,521−100.0% | Sold out |
| Federated Hermes, Inc. | 0 | $0 | 0.00% | −112,028−100.0% | Sold out |
| Susquehanna Portfolio Strategies, LLC | 0 | $0 | 0.00% | −33,937−100.0% | Sold out |