Cabaletta Bio, Inc.
CABA- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001759138
No open-market purchases or sales by Cabaletta Bio, Inc. insiders were filed in the last 90 days; 139 institutions reported holding it in 13F filings for Q2 2026, worth $490.4M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Cabaletta Bio, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 95
- +22 vs. Q3 2025
- Shares held
- 76.2M
- +7.08M (+10.2%) vs. Q3 2025
- Total value
- $166.9M
- +$5.07M (+3.1%) vs. Q3 2025
- New holders
- 30
- 33 more added
- Sold out
- 8
- 18 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CABA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 139 | $490.4M |
| Q1 2026 | 108 | $227.5M |
| Q4 2025 | 95 | $166.9M |
| Q3 2025 | 75 | $162.0M |
| Q2 2025 | 86 | $110.7M |
| Q1 2025 | 93 | $50.3M |
| Q4 2024 | 109 | $87.2M |
| Q3 2024 | 120 | $226.7M |
| Q2 2024 | 142 | $380.0M |
| Q1 2024 | 159 | $870.9M |
| Q4 2023 | 128 | $1.10B |
| Q3 2023 | 97 | $622.6M |
| Q2 2023 | 84 | $470.5M |
| Q1 2023 | 72 | $203.9M |
| Q4 2022 | 61 | $183.9M |
| Q3 2022 | 54 | $7.76M |
| Q2 2022 | 55 | $17.8M |
| Q1 2022 | 62 | $36.9M |
| Q4 2021 | 66 | $68.9M |
| Q3 2021 | 61 | $211.3M |
| Q2 2021 | 63 | $135.5M |
| Q1 2021 | 68 | $180.1M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Cabaletta Bio, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Royal Bank of Canada | 123 | $0 | 0.00% | −91,600−99.9% | Reduced |
| Covestor Ltd | 34 | $0 | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 10 | $22 | 0.00% | 00.0% | Unchanged |
| Optiver Holding B.V. | 24 | $53 | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 60 | $131 | 0.00% | +58+2,900.0% | Added |
| SBI Securities Co., Ltd. | 316 | $692 | 0.00% | −140−30.7% | Reduced |
| Federation des caisses Desjardins du Quebec | 340 | $745 | 0.00% | 00.0% | Unchanged |
| Truvestments Capital LLC | 680 | $1.49K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 811 | $1.78K | 0.00% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 939 | $2.06K | 0.00% | 00.0% | Unchanged |
| Flagship Harbor Advisors, LLC | 1,000 | $2.19K | 0.00% | +1,000 | New |
| BNP Paribas Arbitrage, SA | 1,640 | $3.59K | 0.00% | −191−10.4% | Reduced |
| GF Fund Management Co. Ltd. | 1,891 | $4.14K | 0.00% | +1,891 | New |
| Wells Fargo & Company | 2,000 | $4.38K | 0.00% | −1,000−33.3% | Reduced |
| Canada Pension Plan Investment Board | 3,500 | $7.67K | 0.00% | +3,500 | New |
| The PNC Financial Services Group, Inc. | 4,600 | $10.1K | 0.00% | +4,000+666.7% | Added |
| Mirae Asset Global Investments Co., Ltd. | 4,678 | $10.2K | 0.00% | +4,678 | New |
| JPMorgan Chase & Co | 9,805 | $21.5K | 0.00% | −527,844−98.2% | Reduced |
| HB Wealth Management, LLC | 10,000 | $21.9K | 0.00% | +10,000 | New |
| Manufacturers Life Insurance Company, The | 13,011 | $28.0K | 0.00% | −73−0.6% | Reduced |
| FMR LLC | 13,045 | $28.6K | 0.00% | −1,019−7.2% | Reduced |
| Bank of America Corp | 14,392 | $31.5K | 0.00% | −253,666−94.6% | Reduced |
| Private Advisor Group, LLC | 14,725 | $32.2K | 0.00% | +14,725 | New |
| CRA Financial Services, LLC | 15,000 | $32.9K | 0.00% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 15,686 | $34.4K | 0.00% | +15,686 | New |
| Antipodes Partners Ltd | 17,187 | $37.6K | 0.00% | +17,187 | New |
| Clear Harbor Asset Management, LLC | 19,500 | $42.7K | 0.00% | +19,500 | New |
| Jones Financial Companies LLLP | 20,660 | $45.2K | 0.00% | +653+3.3% | Added |
| JustInvest LLC | 22,384 | $49.0K | 0.00% | +233+1.1% | Added |
| Callan Family Office, LLC | 22,575 | $49.4K | 0.00% | +22,575 | New |
| Mercer Global Advisors Inc | 26,510 | $58.1K | 0.00% | +26,510 | New |
| Fred Alger Management, LLC | 28,021 | $61.4K | 0.00% | −31,792−53.2% | Reduced |
| Tower Research Capital LLC (TRC) | 30,345 | $66.5K | 0.00% | +25,978+594.9% | Added |
| SG Americas Securities, LLC | 30,629 | $67.0K | 0.00% | +9,365+44.0% | Added |
| Citadel Advisors LLC | 33,502 | $73.4K | 0.00% | −671,963−95.3% | Reduced |
| Lighthouse Investment Partners, LLC | 38,880 | $85.1K | 0.00% | +38,880 | New |
| LPL Financial LLC | 42,615 | $93.3K | 0.00% | +42,615 | New |
| Jefferies Financial Group Inc. | 45,125 | $98.8K | 0.00% | −2,375−5.0% | Reduced |
| Charles Schwab Investment Management Inc | 50,824 | $111.3K | 0.00% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 51,552 | $112.9K | 0.00% | +51,552 | New |
| Bank of New York Mellon Corp | 54,047 | $118.4K | 0.00% | +6,237+13.0% | Added |
| Matauro, LLC | 55,108 | $120.7K | 0.02% | +55,108 | New |
| Point72 Asset Management, L.P. | 56,648 | $124.1K | 0.00% | +56,648 | New |
| American Century Companies Inc | 58,777 | $128.7K | 0.00% | +46,745+388.5% | Added |
| Quadrature Capital Ltd | 66,377 | $145.4K | 0.00% | +23,465+54.7% | Added |
| Dynamic Technology Lab Private Ltd | 66,789 | $146.0K | 0.03% | +66,789 | New |
| Citigroup Inc | 73,774 | $161.6K | 0.00% | +73,422+20,858.5% | Added |
| TD Asset Management Inc | 88,600 | $194.0K | 0.00% | 00.0% | Unchanged |
| Letko, Brosseau & Associates Inc | 90,475 | $198.1K | 0.00% | +90,475 | New |
| Omers Administration Corp | 95,400 | $208.9K | 0.00% | +95,400 | New |
| Bridgeway Capital Management, LLC | 130,675 | $286.2K | 0.01% | +35,000+36.6% | Added |
| Susquehanna International Group, LLP | 138,281 | $302.8K | 0.00% | −233,827−62.8% | Reduced |
| Hudson Bay Capital Management LP | 138,729 | $303.8K | 0.00% | +138,729 | New |
| Squarepoint Ops LLC | 149,094 | $326.5K | 0.00% | +137,226+1,156.3% | Added |
| Graham Capital Management, L.P. | 151,451 | $331.7K | 0.01% | +151,451 | New |
| XTX Topco Ltd | 155,387 | $340.3K | 0.01% | −128,912−45.3% | Reduced |
| Stonepine Capital Management, LLC | 171,100 | $374.7K | 0.30% | +171,100 | New |
| Invesco Ltd. | 189,195 | $414.3K | 0.00% | +66,395+54.1% | Added |
| Barclays PLC | 220,696 | $483.3K | 0.00% | +217,613+7,058.5% | Added |
| Northern Trust Corp | 238,442 | $522.2K | 0.00% | +11,455+5.0% | Added |
| Boothbay Fund Management, LLC | 243,445 | $533.1K | 0.01% | +243,445 | New |
| Gsa Capital Partners LLP | 303,992 | $666.0K | 0.06% | +303,992 | New |
| Qube Research & Technologies Ltd | 331,225 | $725.4K | 0.00% | +242,068+271.5% | Added |
| Almitas Capital LLC | 387,491 | $848.6K | 0.19% | 00.0% | Unchanged |
| 683 Capital Management, LLC | 388,562 | $851.0K | 0.07% | +388,562 | New |
| UBS Group AG | 415,677 | $910.3K | 0.00% | +10,557+2.6% | Added |
| State Street Corp | 425,478 | $931.8K | 0.00% | +48,678+12.9% | Added |
| Goldman Sachs Group Inc | 430,674 | $943.2K | 0.00% | +158,078+58.0% | Added |
| Raiffeisen Bank International AG | 450,000 | $967.5K | 0.01% | +100,000+28.6% | Added |
| Dimensional Fund Advisors LP | 452,039 | $990.0K | 0.00% | +452,039 | New |
| KVP Capital Advisors, LP | 505,431 | $1.11M | 1.14% | +505,431 | New |
| Ensign Peak Advisors, Inc | 550,000 | $1.20M | 0.00% | +550,000 | New |
| Jane Street Group, LLC | 662,149 | $1.45M | 0.00% | +557,487+532.7% | Added |
| Burkehill Global Management, LP | 700,000 | $1.53M | 0.10% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 737,900 | $1.62M | 0.00% | +406,900+122.9% | Added |
| Schroder Investment Management Group | 756,637 | $1.63M | 0.00% | +756,637 | New |
| Opaleye Management Inc. | 900,000 | $1.97M | 0.26% | +91,118+11.3% | Added |
| Ikarian Capital, LLC | 900,000 | $1.97M | 0.26% | +900,000 | New |
| Marshall Wace, LLP | 959,076 | $2.10M | 0.00% | −366,967−27.7% | Reduced |
| Geode Capital Management, LLC | 1,085,816 | $2.38M | 0.00% | +165,476+18.0% | Added |
| Price T Rowe Associates Inc | 1,093,959 | $2.40M | 0.00% | −200,990−15.5% | Reduced |
| Schonfeld Strategic Advisors LLC | 1,204,070 | $2.64M | 0.01% | +159,901+15.3% | Added |
| Woodline Partners LP | 1,250,242 | $2.74M | 0.01% | −885,106−41.5% | Reduced |
| Morgan Stanley | 1,343,708 | $2.94M | 0.00% | −130,968−8.9% | Reduced |
| Renaissance Technologies LLC | 1,522,583 | $3.33M | 0.01% | +183,160+13.7% | Added |
| Two Sigma Investments, LP | 1,839,799 | $4.03M | 0.01% | +1,369,324+291.1% | Added |
| Superstring Capital Management LP | 2,253,550 | $4.94M | 2.64% | +709,025+45.9% | Added |
| BlackRock, Inc. | 2,328,470 | $5.10M | 0.00% | +707,598+43.7% | Added |
| Millennium Management LLC | 2,736,912 | $5.99M | 0.00% | +2,050,099+298.5% | Added |
| Cormorant Asset Management, LP | 4,400,000 | $9.64M | 0.55% | −600,000−12.0% | Reduced |
| Vanguard Group Inc | 4,419,458 | $9.68M | 0.00% | +228,699+5.5% | Added |
| Adage Capital Partners GP, L.L.C. | 8,829,758 | $19.3M | 0.03% | 00.0% | Unchanged |
| Jennison Associates LLC | 8,905,699 | $19.5M | 0.01% | +408,162+4.8% | Added |
| Bain Capital Life Sciences Investors, LLC | 9,677,125 | $21.2M | 1.62% | 00.0% | Unchanged |
| T. Rowe Price Investment Management, Inc. | 9,858,257 | $21.6M | 0.01% | +1,495,768+17.9% | Added |
| Heights Capital Management, Inc | 0 | $0 | 0.00% | −2,084,202−100.0% | Sold out |
| Alyeska Investment Group, L.P. | 0 | $0 | 0.00% | −1,300,000−100.0% | Sold out |
| Acadian Asset Management LLC | 0 | $0 | 0.00% | −186,521−100.0% | Sold out |
| Federated Hermes, Inc. | 0 | $0 | 0.00% | −112,028−100.0% | Sold out |
| Susquehanna Portfolio Strategies, LLC | 0 | $0 | 0.00% | −33,937−100.0% | Sold out |