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Cabaletta Bio, Inc.

CABA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001759138

No open-market purchases or sales by Cabaletta Bio, Inc. insiders were filed in the last 90 days; 139 institutions reported holding it in 13F filings for Q2 2026, worth $490.4M in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Cabaletta Bio, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
75
−11 vs. Q2 2025
Shares held
69.2M
−3.55M (−4.9%) vs. Q2 2025
Total value
$162.0M
+$51.3M (+46.3%) vs. Q2 2025
New holders
10
24 more added
Sold out
21
31 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CABA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 75 institutions
Q1 2021: 68 institutionsQ2 2021: 63 institutionsQ3 2021: 61 institutionsQ4 2021: 66 institutionsQ1 2022: 62 institutionsQ2 2022: 55 institutionsQ3 2022: 54 institutionsQ4 2022: 61 institutionsQ1 2023: 72 institutionsQ2 2023: 84 institutionsQ3 2023: 97 institutionsQ4 2023: 128 institutionsQ1 2024: 159 institutionsQ2 2024: 142 institutionsQ3 2024: 120 institutionsQ4 2024: 109 institutionsQ1 2025: 93 institutionsQ2 2025: 86 institutionsQ3 2025: 75 institutionsQ4 2025: 95 institutionsQ1 2026: 108 institutionsQ2 2026: 139 institutions
Value heldQ3 2025: $162.0M
Q1 2021: $180.1MQ2 2021: $135.5MQ3 2021: $211.3MQ4 2021: $68.9MQ1 2022: $36.9MQ2 2022: $17.8MQ3 2022: $7.76MQ4 2022: $183.9MQ1 2023: $203.9MQ2 2023: $470.5MQ3 2023: $622.6MQ4 2023: $1.10BQ1 2024: $870.9MQ2 2024: $380.0MQ3 2024: $226.7MQ4 2024: $87.2MQ1 2025: $50.3MQ2 2025: $110.7MQ3 2025: $162.0MQ4 2025: $166.9MQ1 2026: $227.5MQ2 2026: $490.4M
Institutions holding CABA and their total value by quarter
QuarterHoldersValue
Q2 2026139$490.4M
Q1 2026108$227.5M
Q4 202595$166.9M
Q3 202575$162.0M
Q2 202586$110.7M
Q1 202593$50.3M
Q4 2024109$87.2M
Q3 2024120$226.7M
Q2 2024142$380.0M
Q1 2024159$870.9M
Q4 2023128$1.10B
Q3 202397$622.6M
Q2 202384$470.5M
Q1 202372$203.9M
Q4 202261$183.9M
Q3 202254$7.76M
Q2 202255$17.8M
Q1 202262$36.9M
Q4 202166$68.9M
Q3 202161$211.3M
Q2 202163$135.5M
Q1 202168$180.1M

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Cabaletta Bio, Inc.; share changes are against Q2 2025.

Institutions holding CABA in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Bain Capital Life Sciences Investors, LLC9,677,125$22.6M1.50%00.0%Unchanged
Adage Capital Partners GP, L.L.C.8,829,758$20.7M0.03%00.0%Unchanged
Jennison Associates LLC8,497,537$19.9M0.01%+2,477,370+41.2%Added
T. Rowe Price Investment Management, Inc.8,362,489$19.6M0.01%+1,568,701+23.1%Added
Cormorant Asset Management, LP5,000,000$11.7M0.81%00.0%Unchanged
Vanguard Group Inc4,190,759$9.81M0.00%+740,032+21.4%Added
Woodline Partners LP2,135,348$5.00M0.02%+916,884+75.2%Added
Heights Capital Management, Inc2,084,202$4.88M1.55%−1,059,904−33.7%Reduced
BlackRock, Inc.1,620,872$3.79M0.00%+650,271+67.0%Added
Superstring Capital Management LP1,544,525$3.61M3.56%+483,761+45.6%Added
Morgan Stanley1,474,676$3.45M0.00%+149,870+11.3%Added
Renaissance Technologies LLC1,339,423$3.13M0.00%+1,213,323+962.2%Added
Marshall Wace, LLP1,326,043$3.10M0.00%+1,135,086+594.4%Added
Alyeska Investment Group, L.P.1,300,000$3.04M0.01%−3,500,000−72.9%Reduced
Price T Rowe Associates Inc1,294,949$3.03M0.00%−892,090−40.8%Reduced
Schonfeld Strategic Advisors LLC1,044,169$2.44M0.02%−440,667−29.7%Reduced
Geode Capital Management, LLC920,340$2.15M0.00%+366,878+66.3%Added
Opaleye Management Inc.808,882$1.89M0.27%+808,882New
Citadel Advisors LLC705,465$1.65M0.00%−982,515−58.2%Reduced
Burkehill Global Management, LP700,000$1.64M0.09%−1,200,000−63.2%Reduced
Millennium Management LLC686,813$1.61M0.00%−168,517−19.7%Reduced
JPMorgan Chase & Co537,649$1.26M0.00%+456,853+565.4%Added
Two Sigma Investments, LP470,475$1.10M0.00%+218,118+86.4%Added
UBS Group AG405,120$948.0K0.00%−66,922−14.2%Reduced
Almitas Capital LLC387,491$906.7K0.21%+20,000+5.4%Added
State Street Corp376,800$881.7K0.00%+158,833+72.9%Added
Susquehanna International Group, LLP372,108$870.7K0.00%+248,483+201.0%Added
Raiffeisen Bank International AG350,000$833.0K0.01%+50,000+16.7%Added
Two Sigma Advisers, LP331,000$774.5K0.00%−82,600−20.0%Reduced
XTX Topco Ltd284,299$665.3K0.03%+187,039+192.3%Added
Goldman Sachs Group Inc272,596$637.9K0.00%−80,711−22.8%Reduced
Bank of America Corp268,058$627.3K0.00%−230,185−46.2%Reduced
Northern Trust Corp226,987$531.1K0.00%+93,967+70.6%Added
Acadian Asset Management LLC186,521$433.0K0.00%+171,380+1,131.9%Added
Invesco Ltd.122,800$287.4K0.00%+37,969+44.8%Added
Federated Hermes, Inc.112,028$262.1K0.00%−232,512−67.5%Reduced
Jane Street Group, LLC104,662$244.9K0.00%−133,663−56.1%Reduced
Bridgeway Capital Management, LLC95,675$223.9K0.00%+50,000+109.5%Added
Royal Bank of Canada91,723$214.0K0.00%+91,660+145,492.1%Added
Qube Research & Technologies Ltd89,157$208.6K0.00%+89,157New
TD Asset Management Inc88,600$207.3K0.00%00.0%Unchanged
Fred Alger Management, LLC59,813$140.0K0.00%00.0%Unchanged
Charles Schwab Investment Management Inc50,824$118.9K0.00%+203+0.4%Added
Bank of New York Mellon Corp47,810$111.9K0.00%00.0%Unchanged
Jefferies Financial Group Inc.47,500$111.2K0.00%−1,949,708−97.6%Reduced
Quadrature Capital Ltd42,912$100.4K0.00%+42,912New
Cubist Systematic Strategies, LLC37,744$88.3K0.00%−197,526−84.0%Reduced
Susquehanna Portfolio Strategies, LLC33,937$79.4K0.00%+33,937New
JustInvest LLC22,151$51.8K0.00%−2,797−11.2%Reduced
SG Americas Securities, LLC21,264$50.0K0.00%−2,784−11.6%Reduced
Jones Financial Companies LLLP20,007$47.2K0.00%+20,007New
CRA Financial Services, LLC15,000$35.1K0.00%+4,000+36.4%Added
FMR LLC14,064$32.9K0.00%−1,392−9.0%Reduced
Manufacturers Life Insurance Company, The13,084$30.6K0.00%−26,686−67.1%Reduced
American Century Companies Inc12,032$28.2K0.00%+12,032New
Squarepoint Ops LLC11,868$27.8K0.00%−59,573−83.4%Reduced
Rangeley Capital, LLC11,300$26.4K0.02%−4,700−29.4%Reduced
Caitong International Asset Management Co., Ltd8,983$21.0K0.01%+8,983New
Point72 Asia (Singapore) Pte. Ltd.8,935$20.9K0.00%−25,832−74.3%Reduced
Tower Research Capital LLC (TRC)4,367$10.2K0.00%−46,669−91.4%Reduced
Barclays PLC3,083$7.21K0.00%−6,654−68.3%Reduced
Wells Fargo & Company3,000$7.02K0.00%−3,686−55.1%Reduced
BNP Paribas Arbitrage, SA1,831$4.29K0.00%−47,235−96.3%Reduced
Rise Advisors, LLC1,083$2.53K0.00%00.0%Unchanged
Russell Investments Group, Ltd.939$2.20K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC811$1.90K0.00%−101−11.1%Reduced
Truvestments Capital LLC680$1.59K0.00%−1,293−65.5%Reduced
The PNC Financial Services Group, Inc.600$1.40K0.00%−709−54.2%Reduced
SBI Securities Co., Ltd.456$1.07K0.00%−6,060−93.0%Reduced
Citigroup Inc352$8240.00%−62,147−99.4%Reduced
Federation des caisses Desjardins du Quebec340$7960.00%00.0%Unchanged
Optiver Holding B.V.24$560.00%+24New
SRS Capital Advisors, Inc.10$230.00%+10New
Northwestern Mutual Wealth Management Co2$50.00%+2New
Covestor Ltd34$00.00%00.0%Unchanged
Anson Funds Management LP0$00.00%−1,822,830−100.0%Sold out
Blue Owl Capital Holdings LP0$00.00%−1,125,000−100.0%Sold out
Cantor Fitzgerald, L. P.0$00.00%−532,500−100.0%Sold out
Prudential Financial Inc0$00.00%−284,000−100.0%Sold out
AXA S.A.0$00.00%−270,516−100.0%Sold out
HRT Financial LP0$00.00%−124,395−100.0%Sold out
Thrivent Financial for Lutherans0$00.00%−95,327−100.0%Sold out
TCG Crossover Management, LLC0$00.00%−86,795−100.0%Sold out
Jain Global LLC0$00.00%−56,160−100.0%Sold out
MYDA Advisors LLC0$00.00%−40,000−100.0%Sold out
AQR Capital Management LLC0$00.00%−32,129−100.0%Sold out
Catalyst Funds Management Pty Ltd0$00.00%−21,000−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−16,491−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−13,070−100.0%Sold out
DRW Securities, LLC0$00.00%−12,840−100.0%Sold out
Clear Street Markets LLC0$00.00%−4,824−100.0%Sold out
Point72 (DIFC) Ltd0$00.00%−2,432−100.0%Sold out
CWM, LLC0$00.00%−1,597−100.0%Sold out
Mid-American Wealth Advisory Group, Inc.0$00.00%−91−100.0%Sold out
EverSource Wealth Advisors, LLC0$00.00%−41−100.0%Sold out
True Wealth Design, LLC0$00.00%−17−100.0%Sold out