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Cabaletta Bio, Inc.

CABA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001759138

No open-market purchases or sales by Cabaletta Bio, Inc. insiders were filed in the last 90 days; 139 institutions reported holding it in 13F filings for Q2 2026, worth $490.4M in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Cabaletta Bio, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
86
−7 vs. Q1 2025
Shares held
72.8M
+36.5M (+100.4%) vs. Q1 2025
Total value
$110.7M
+$60.3M (+119.9%) vs. Q1 2025
New holders
26
23 more added
Sold out
33
28 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CABA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 86 institutions
Q1 2021: 68 institutionsQ2 2021: 63 institutionsQ3 2021: 61 institutionsQ4 2021: 66 institutionsQ1 2022: 62 institutionsQ2 2022: 55 institutionsQ3 2022: 54 institutionsQ4 2022: 61 institutionsQ1 2023: 72 institutionsQ2 2023: 84 institutionsQ3 2023: 97 institutionsQ4 2023: 128 institutionsQ1 2024: 159 institutionsQ2 2024: 142 institutionsQ3 2024: 120 institutionsQ4 2024: 109 institutionsQ1 2025: 93 institutionsQ2 2025: 86 institutionsQ3 2025: 75 institutionsQ4 2025: 95 institutionsQ1 2026: 108 institutionsQ2 2026: 139 institutions
Value heldQ2 2025: $110.7M
Q1 2021: $180.1MQ2 2021: $135.5MQ3 2021: $211.3MQ4 2021: $68.9MQ1 2022: $36.9MQ2 2022: $17.8MQ3 2022: $7.76MQ4 2022: $183.9MQ1 2023: $203.9MQ2 2023: $470.5MQ3 2023: $622.6MQ4 2023: $1.10BQ1 2024: $870.9MQ2 2024: $380.0MQ3 2024: $226.7MQ4 2024: $87.2MQ1 2025: $50.3MQ2 2025: $110.7MQ3 2025: $162.0MQ4 2025: $166.9MQ1 2026: $227.5MQ2 2026: $490.4M
Institutions holding CABA and their total value by quarter
QuarterHoldersValue
Q2 2026139$490.4M
Q1 2026108$227.5M
Q4 202595$166.9M
Q3 202575$162.0M
Q2 202586$110.7M
Q1 202593$50.3M
Q4 2024109$87.2M
Q3 2024120$226.7M
Q2 2024142$380.0M
Q1 2024159$870.9M
Q4 2023128$1.10B
Q3 202397$622.6M
Q2 202384$470.5M
Q1 202372$203.9M
Q4 202261$183.9M
Q3 202254$7.76M
Q2 202255$17.8M
Q1 202262$36.9M
Q4 202166$68.9M
Q3 202161$211.3M
Q2 202163$135.5M
Q1 202168$180.1M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Cabaletta Bio, Inc.; share changes are against Q1 2025.

Institutions holding CABA in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Bain Capital Life Sciences Investors, LLC9,677,125$14.7M1.84%+6,916,237+250.5%Added
Adage Capital Partners GP, L.L.C.8,829,758$13.4M0.02%+5,195,285+142.9%Added
T. Rowe Price Investment Management, Inc.6,793,788$10.3M0.01%+2,823,762+71.1%Added
Jennison Associates LLC6,020,167$9.15M0.01%+3,586,439+147.4%Added
Cormorant Asset Management, LP5,000,000$7.60M0.57%+5,000,000New
Alyeska Investment Group, L.P.4,800,000$7.30M0.03%+4,800,000New
Vanguard Group Inc3,450,727$5.25M0.00%+606,488+21.3%Added
Heights Capital Management, Inc3,144,106$4.78M1.50%+3,144,106New
Price T Rowe Associates Inc2,187,039$3.33M0.00%+1,697,718+347.0%Added
Jefferies Financial Group Inc.1,997,208$3.04M0.05%+1,997,208New
Burkehill Global Management, LP1,900,000$2.89M0.21%+1,900,000New
Anson Funds Management LP1,822,830$2.77M0.51%+1,822,830New
Citadel Advisors LLC1,687,980$2.57M0.00%+1,687,630+482,180.0%Added
Schonfeld Strategic Advisors LLC1,484,836$2.26M0.02%−177,565−10.7%Reduced
Morgan Stanley1,324,806$2.01M0.00%−384,082−22.5%Reduced
Woodline Partners LP1,218,464$1.85M0.01%+1,218,464New
Blue Owl Capital Holdings LP1,125,000$1.71M0.55%+1,125,000New
Superstring Capital Management LP1,060,764$1.61M2.01%+601,792+131.1%Added
BlackRock, Inc.970,601$1.48M0.00%−2,481,546−71.9%Reduced
Millennium Management LLC855,330$1.30M0.00%+686,431+406.4%Added
Geode Capital Management, LLC553,462$841.6K0.00%−587,835−51.5%Reduced
Cantor Fitzgerald, L. P.532,500$809.4K0.02%−952,085−64.1%Reduced
Bank of America Corp498,243$757.3K0.00%−485,852−49.4%Reduced
UBS Group AG472,042$717.5K0.00%−18,158−3.7%Reduced
Two Sigma Advisers, LP413,600$628.7K0.00%−57,900−12.3%Reduced
Almitas Capital LLC367,491$558.6K0.14%00.0%Unchanged
Goldman Sachs Group Inc353,307$537.0K0.00%+22,766+6.9%Added
Raiffeisen Bank International AG300,000$531.0K0.01%00.0%Unchanged
Federated Hermes, Inc.344,540$523.7K0.00%+1,129+0.3%Added
Prudential Financial Inc284,000$431.7K0.00%−3,490−1.2%Reduced
AXA S.A.270,516$411.2K0.00%+439+0.2%Added
Two Sigma Investments, LP252,357$383.6K0.00%−69,054−21.5%Reduced
Jane Street Group, LLC238,325$362.3K0.00%+238,325New
Cubist Systematic Strategies, LLC235,270$357.6K0.00%+235,270New
State Street Corp217,967$331.3K0.00%−720,751−76.8%Reduced
Marshall Wace, LLP190,957$290.3K0.00%+157,497+470.7%Added
Northern Trust Corp133,020$202.2K0.00%−266,746−66.7%Reduced
Renaissance Technologies LLC126,100$191.7K0.00%+115,200+1,056.9%Added
HRT Financial LP124,395$189.0K0.00%+124,395New
Susquehanna International Group, LLP123,625$187.9K0.00%+65,845+114.0%Added
XTX Topco Ltd97,260$147.8K0.01%+97,260New
Thrivent Financial for Lutherans95,327$145.0K0.00%00.0%Unchanged
TD Asset Management Inc88,600$134.7K0.00%00.0%Unchanged
TCG Crossover Management, LLC86,795$131.9K0.02%00.0%Unchanged
Invesco Ltd.84,831$128.9K0.00%+23,156+37.5%Added
JPMorgan Chase & Co80,796$122.8K0.00%−170,641−67.9%Reduced
Squarepoint Ops LLC71,441$108.6K0.00%+71,441New
Citigroup Inc62,499$95.0K0.00%+31,037+98.6%Added
Fred Alger Management, LLC59,813$90.9K0.00%−417,397−87.5%Reduced
Jain Global LLC56,160$85.4K0.00%+56,160New
Tower Research Capital LLC (TRC)51,036$77.6K0.00%+44,621+695.6%Added
Charles Schwab Investment Management Inc50,621$76.9K0.00%−109,245−68.3%Reduced
BNP Paribas Arbitrage, SA49,066$74.6K0.00%−12,339−20.1%Reduced
Bank of New York Mellon Corp47,810$72.7K0.00%−107,364−69.2%Reduced
Bridgeway Capital Management, LLC45,675$69.4K0.00%00.0%Unchanged
MYDA Advisors LLC40,000$60.8K0.02%+40,000New
Manufacturers Life Insurance Company, The39,770$60.5K0.00%−17,266−30.3%Reduced
Point72 Asia (Singapore) Pte. Ltd.34,767$52.8K0.01%+34,767New
AQR Capital Management LLC32,129$48.8K0.00%−41,827−56.6%Reduced
JustInvest LLC24,948$37.9K0.00%+5,569+28.7%Added
SG Americas Securities, LLC24,048$37.0K0.00%−12,228−33.7%Reduced
Catalyst Funds Management Pty Ltd21,000$31.9K0.01%+21,000New
Two Sigma Securities, LLC16,491$25.1K0.00%+16,491New
Rangeley Capital, LLC16,000$24.3K0.03%+16,000New
FMR LLC15,456$23.5K0.00%+11,295+271.4%Added
Acadian Asset Management LLC15,141$23.0K0.00%−667,529−97.8%Reduced
Hudson Bay Capital Management LP13,070$19.9K0.00%+13,070New
DRW Securities, LLC12,840$19.5K0.00%+12,840New
CRA Financial Services, LLC11,000$16.7K0.00%00.0%Unchanged
Barclays PLC9,737$14.8K0.00%−46,701−82.7%Reduced
Wells Fargo & Company6,686$10.2K0.00%−25,293−79.1%Reduced
SBI Securities Co., Ltd.6,516$9.90K0.00%+3,600+123.5%Added
Clear Street Markets LLC4,824$7.33K0.00%+4,824New
Point72 (DIFC) Ltd2,432$3.70K0.00%+2,432New
Truvestments Capital LLC1,973$3.00K0.00%00.0%Unchanged
CWM, LLC1,597$2.00K0.00%−4,594−74.2%Reduced
The PNC Financial Services Group, Inc.1,309$1.99K0.00%+1,155+750.0%Added
Rise Advisors, LLC1,083$1.65K0.00%+1,083New
Russell Investments Group, Ltd.939$1.43K0.00%+939New
Nisa Investment Advisors, LLC912$1.39K0.00%+718+370.1%Added
Federation des caisses Desjardins du Quebec340$5170.00%00.0%Unchanged
Mid-American Wealth Advisory Group, Inc.91$1380.00%+91New
EverSource Wealth Advisors, LLC41$620.00%−49−54.4%Reduced
True Wealth Design, LLC17$260.00%−46−73.0%Reduced
Royal Bank of Canada63$00.00%−2,300−97.3%Reduced
Covestor Ltd34$00.00%−3−8.1%Reduced
Integral Health Asset Management, LLC0$00.00%−850,000−100.0%Sold out
Nuveen, LLC0$00.00%−434,389−100.0%Sold out
HealthInvest Partners AB0$00.00%−182,354−100.0%Sold out
Alliancebernstein L.P.0$00.00%−64,630−100.0%Sold out
Rhumbline Advisers0$00.00%−61,388−100.0%Sold out
Stifel Financial Corp0$00.00%−49,554−100.0%Sold out
Comerica Bank0$00.00%−41,599−100.0%Sold out
Callan Family Office, LLC0$00.00%−41,599−100.0%Sold out
Intech Investment Management LLC0$00.00%−31,148−100.0%Sold out
Mirae Asset Global ETFs Holdings Ltd.0$00.00%−26,622−100.0%Sold out
Envestnet Asset Management Inc0$00.00%−25,540−100.0%Sold out
Deutsche Bank AG0$00.00%−22,361−100.0%Sold out
Corebridge Financial, Inc.0$00.00%−21,981−100.0%Sold out
Jones Financial Companies LLLP0$00.00%−18,507−100.0%Sold out