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Biocryst Pharmaceuticals Inc

BCRX
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0000882796

No open-market purchases or sales by Biocryst Pharmaceuticals Inc insiders were filed in the last 90 days; 319 institutions reported holding it in 13F filings for Q2 2026, worth $2.61B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Biocryst Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
273
−8 vs. Q3 2025
Shares held
212.5M
+19.7M (+10.2%) vs. Q3 2025
Total value
$1.66B
+$193.5M (+13.2%) vs. Q3 2025
New holders
49
91 more added
Sold out
57
101 more reduced

5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting BCRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 273 institutions
Q1 2021: 191 institutionsQ2 2021: 195 institutionsQ3 2021: 197 institutionsQ4 2021: 206 institutionsQ1 2022: 233 institutionsQ2 2022: 221 institutionsQ3 2022: 234 institutionsQ4 2022: 230 institutionsQ1 2023: 242 institutionsQ2 2023: 236 institutionsQ3 2023: 233 institutionsQ4 2023: 236 institutionsQ1 2024: 238 institutionsQ2 2024: 242 institutionsQ3 2024: 257 institutionsQ4 2024: 258 institutionsQ1 2025: 274 institutionsQ2 2025: 294 institutionsQ3 2025: 286 institutionsQ4 2025: 273 institutionsQ1 2026: 303 institutionsQ2 2026: 319 institutions
Value heldQ4 2025: $1.66B
Q1 2021: $1.06BQ2 2021: $1.65BQ3 2021: $1.48BQ4 2021: $1.63BQ1 2022: $2.07BQ2 2022: $1.61BQ3 2022: $1.87BQ4 2022: $1.80BQ1 2023: $1.42BQ2 2023: $1.23BQ3 2023: $1.24BQ4 2023: $1.06BQ1 2024: $915.0MQ2 2024: $1.08BQ3 2024: $1.32BQ4 2024: $1.26BQ1 2025: $1.32BQ2 2025: $1.77BQ3 2025: $1.47BQ4 2025: $1.66BQ1 2026: $2.37BQ2 2026: $2.61B
Institutions holding BCRX and their total value by quarter
QuarterHoldersValue
Q2 2026319$2.61B
Q1 2026303$2.37B
Q4 2025273$1.66B
Q3 2025286$1.47B
Q2 2025294$1.77B
Q1 2025274$1.32B
Q4 2024258$1.26B
Q3 2024257$1.32B
Q2 2024242$1.08B
Q1 2024238$915.0M
Q4 2023236$1.06B
Q3 2023233$1.24B
Q2 2023236$1.23B
Q1 2023242$1.42B
Q4 2022230$1.80B
Q3 2022234$1.87B
Q2 2022221$1.61B
Q1 2022233$2.07B
Q4 2021206$1.63B
Q3 2021197$1.48B
Q2 2021195$1.65B
Q1 2021191$1.06B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Biocryst Pharmaceuticals Inc; share changes are against Q3 2025.

Institutions holding BCRX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
HSBC Holdings PLC24,133$188.1K0.00%−37,803−61.0%Reduced
LPL Financial LLC24,480$190.9K0.00%+7,467+43.9%Added
Abel Hall, LLC24,898$194.2K0.05%+24,898New
Csenge Advisory Group25,000$195.0K0.01%00.0%Unchanged
Janney Montgomery Scott LLC26,133$204.0K0.00%−1,750−6.3%Reduced
Rockefeller Capital Management L.P.26,797$209.0K0.00%+21,472+403.2%Added
Vinva Investment Management Ltd18,733$214.2K0.00%−34,328−64.7%Reduced
Public Employees Retirement Association of Colorado27,713$216.0K0.00%00.0%Unchanged
Leisure Capital Management28,000$218.4K0.07%00.0%Unchanged
Aigen Investment Management, LP28,058$218.9K0.05%−72,345−72.1%Reduced
Teacher Retirement System of Texas29,643$231.2K0.00%−19,179−39.3%Reduced
May Barnhard Investments LLC30,000$234.0K0.11%00.0%Unchanged
Quarry LP30,000$234.0K0.04%+30,000New
Mariner, LLC31,495$245.6K0.00%+11,807+60.0%Added
Universal- Beteiligungs- und Servicegesellschaft mbH31,791$248.0K0.00%−9,378−22.8%Reduced
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management32,910$256.7K0.00%+8,474+34.7%Added
China Universal Asset Management Co., Ltd.34,308$267.6K0.02%−2,488−6.8%Reduced
Fiduciary Trust Co37,253$290.6K0.00%+11,234+43.2%Added
Grimes & Company, Inc.37,952$296.0K0.01%−16,011−29.7%Reduced
Caxton Associates LLP38,144$297.5K0.01%+22,432+142.8%Added
Commerce Bank39,065$304.7K0.00%+9,350+31.5%Added
Erste Asset Management GmbH40,000$308.4K0.00%00.0%Unchanged
KLP Kapitalforvaltning AS42,900$334.6K0.00%+3,100+7.8%Added
ADAR1 Capital Management, LLC45,000$351.0K0.03%+45,000New
ProShare Advisors LLC47,604$371.3K0.00%+4,307+9.9%Added
Creative Planning49,780$388.3K0.00%−38,697−43.7%Reduced
GWM Advisors LLC50,041$390.3K0.00%+50,041New
Persistent Asset Partners Ltd51,701$403.3K0.19%+51,701New
State of Wyoming51,893$404.8K0.04%+14,810+39.9%Added
Voleon Capital Management LP52,345$408.3K0.01%−55,185−51.3%Reduced
DekaBank Deutsche Girozentrale73,765$413.0K0.00%00.0%Unchanged
Envestnet Asset Management Inc54,065$421.7K0.00%+24,352+82.0%Added
Arizona State Retirement System56,082$437.4K0.00%−2,706−4.6%Reduced
State Board of Administration of Florida Retirement System56,361$439.6K0.00%00.0%Unchanged
Entropy Technologies, LP56,517$440.8K0.02%−11,000−16.3%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)57,351$447.3K0.00%00.0%Unchanged
Police & Firemen's Retirement System of New Jersey58,046$452.8K0.00%00.0%Unchanged
Citigroup Inc58,269$454.5K0.00%+29,922+105.6%Added
Sanctuary Advisors, LLC58,571$456.9K0.00%+15,544+36.1%Added
CWM Advisors, LLC60,049$468.4K0.04%+124+0.2%Added
Group One Trading, L.P.60,524$472.1K0.01%+20,997+53.1%Added
Personal Cfo Solutions, LLC62,400$486.7K0.08%+212+0.3%Added
University of Texas/Texas Am Investment Managment Co64,507$503.2K0.07%+64,507New
Arrowstreet Capital, Limited Partnership66,244$516.7K0.00%−5,159,742−98.7%Reduced
Campbell & CO Investment Adviser LLC68,559$534.8K0.03%−40,995−37.4%Reduced
Lazard Asset Management LLC69,598$542.9K0.00%+16,290+30.6%Added
CI Private Wealth, LLC70,378$548.8K0.00%−397−0.6%Reduced
Jain Global LLC74,455$580.7K0.01%+74,455New
Quest Partners LLC76,405$596.0K0.03%+12,302+19.2%Added
Intech Investment Management LLC79,418$619.5K0.01%−21,818−21.6%Reduced
Commonwealth Equity Services, LLC79,747$622.0K0.00%−46,312−36.7%Reduced
Advisor Group Holdings, Inc.82,766$645.6K0.00%+21,011+34.0%Added
Graham Capital Management, L.P.83,876$654.2K0.02%−183,854−68.7%Reduced
Acadian Asset Management LLC85,300$662.0K0.00%−754,103−89.8%Reduced
Wellington Management Group LLP86,520$674.9K0.00%−7,010−7.5%Reduced
Panagora Asset Management Inc88,876$693.2K0.00%−34,990−28.2%Reduced
Virtus Investment Advisers, Inc.90,278$704.2K0.19%+47,548+111.3%Added
Counterweight Ventures, LLC95,384$744.0K0.42%+2,000+2.1%Added
Manufacturers Life Insurance Company, The97,634$761.5K0.00%−8,646−8.1%Reduced
Empire Financial Management Company, LLC100,000$780.0K0.17%+100,000New
New York State Common Retirement Fund100,690$785.4K0.00%+34,392+51.9%Added
SEI Investments Co103,157$804.6K0.00%−259,059−71.5%Reduced
American Century Companies Inc105,385$822.0K0.00%−10,905−9.4%Reduced
Gsa Capital Partners LLP108,229$844.0K0.07%−82,065−43.1%Reduced
Hennion & Walsh Asset Management, Inc.112,539$877.8K0.03%+26,794+31.2%Added
Tudor Investment Corp Et Al114,541$893.4K0.00%+16,366+16.7%Added
MetLife Investment Management117,853$919.3K0.00%−102−0.1%Reduced
Headlands Technologies LLC118,473$924.1K0.08%+4,134+3.6%Added
Mirae Asset Global ETFs Holdings Ltd.119,567$929.5K0.00%+3,366+2.9%Added
Elo Mutual Pension Insurance Co123,539$963.6K0.01%−3,965−3.1%Reduced
SG Americas Securities, LLC126,685$988.0K0.00%−102,210−44.7%Reduced
QTR Family Wealth, LLC154,062$1.01M0.44%−3,075−2.0%Reduced
Raymond James Financial Inc131,103$1.02M0.00%+26,001+24.7%Added
Millennium Management LLC137,626$1.07M0.00%−323,321−70.1%Reduced
OP Asset Management Ltd139,207$1.09M0.01%+139,207New
Schonfeld Strategic Advisors LLC141,449$1.10M0.01%−25,392−15.2%Reduced
Profund Advisors LLC141,985$1.11M0.03%+61,966+77.4%Added
Mackenzie Financial Corp150,728$1.15M0.00%+21,411+16.6%Added
Royal Bank of Canada161,456$1.26M0.00%−23,959−12.9%Reduced
Price T Rowe Associates Inc177,392$1.38M0.00%+16,044+9.9%Added
Diadema Partners LP190,928$1.49M0.89%+190,928New
California State Teachers Retirement System191,847$1.50M0.00%+9,381+5.1%Added
Integral Health Asset Management, LLC200,000$1.56M0.08%+200,000New
Legal & General Group Plc210,999$1.65M0.00%−15,166−6.7%Reduced
Gotham Asset Management, LLC216,946$1.69M0.01%−126,825−36.9%Reduced
Engineers Gate Manager LP224,543$1.75M0.02%−218,304−49.3%Reduced
Russell Investments Group, Ltd.229,226$1.79M0.00%−85,267−27.1%Reduced
Virginia Retirement Systems Et Al233,354$1.82M0.01%+120,350+106.5%Added
Wells Fargo & Company233,639$1.82M0.00%+100,603+75.6%Added
Bridgewater Associates, LP235,572$1.84M0.01%−175,931−42.8%Reduced
Phocas Financial Corp.250,797$1.96M0.25%+250,797New
Walleye Capital LLC251,670$1.96M0.01%+24,606+10.8%Added
Hussman Strategic Advisors, Inc.252,000$1.97M0.48%+42,000+20.0%Added
Rhumbline Advisers266,562$2.08M0.00%−60,273−18.4%Reduced
Doliver Advisors, LP274,328$2.14M0.54%00.0%Unchanged
Alliancebernstein L.P.278,190$2.17M0.00%−143−0.1%Reduced
Federated Hermes, Inc.292,850$2.28M0.00%+27,345+10.3%Added
Ishara Investments LP300,000$2.34M2.72%+300,000New
Victory Capital Management Inc325,051$2.54M0.00%+265,564+446.4%Added
Canada Pension Plan Investment Board327,941$2.56M0.00%+97,600+42.4%Added