Biocryst Pharmaceuticals Inc
BCRX- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0000882796
No open-market purchases or sales by Biocryst Pharmaceuticals Inc insiders were filed in the last 90 days; 319 institutions reported holding it in 13F filings for Q2 2026, worth $2.61B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Biocryst Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 273
- −8 vs. Q3 2025
- Shares held
- 212.5M
- +19.7M (+10.2%) vs. Q3 2025
- Total value
- $1.66B
- +$193.5M (+13.2%) vs. Q3 2025
- New holders
- 49
- 91 more added
- Sold out
- 57
- 101 more reduced
5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting BCRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 319 | $2.61B |
| Q1 2026 | 303 | $2.37B |
| Q4 2025 | 273 | $1.66B |
| Q3 2025 | 286 | $1.47B |
| Q2 2025 | 294 | $1.77B |
| Q1 2025 | 274 | $1.32B |
| Q4 2024 | 258 | $1.26B |
| Q3 2024 | 257 | $1.32B |
| Q2 2024 | 242 | $1.08B |
| Q1 2024 | 238 | $915.0M |
| Q4 2023 | 236 | $1.06B |
| Q3 2023 | 233 | $1.24B |
| Q2 2023 | 236 | $1.23B |
| Q1 2023 | 242 | $1.42B |
| Q4 2022 | 230 | $1.80B |
| Q3 2022 | 234 | $1.87B |
| Q2 2022 | 221 | $1.61B |
| Q1 2022 | 233 | $2.07B |
| Q4 2021 | 206 | $1.63B |
| Q3 2021 | 197 | $1.48B |
| Q2 2021 | 195 | $1.65B |
| Q1 2021 | 191 | $1.06B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Biocryst Pharmaceuticals Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vanguard Group Inc | 22,273,375 | $173.7M | 0.00% | +482,494+2.2% | Added |
| BlackRock, Inc. | 21,137,791 | $164.9M | 0.00% | −108,085−0.5% | Reduced |
| Ra Capital Management, L.P. | 15,827,186 | $123.5M | 1.26% | +15,827,186 | New |
| Deerfield Management Company, L.P. (Series C) | 14,341,000 | $111.9M | 1.43% | +2,172,000+17.8% | Added |
| State Street Corp | 11,073,211 | $86.4M | 0.00% | +1,265,773+12.9% | Added |
| Kynam Capital Management, LP | 9,366,526 | $73.1M | 4.76% | −23,744−0.3% | Reduced |
| Janus Henderson Group PLC | 7,404,386 | $57.8M | 0.03% | +7,310,745+7,807.2% | Added |
| UBS Group AG | 5,263,914 | $41.1M | 0.01% | −703,823−11.8% | Reduced |
| Geode Capital Management, LLC | 5,053,786 | $39.4M | 0.00% | +1,4790.0% | Added |
| Two Sigma Investments, LP | 4,515,317 | $35.2M | 0.05% | +95,688+2.2% | Added |
| Two Sigma Advisers, LP | 4,089,112 | $31.9M | 0.06% | −151,600−3.6% | Reduced |
| Royalty Pharma Sub-Manager, LLC | 3,846,154 | $30.0M | 17.51% | +3,846,154 | New |
| Nuveen, LLC | 3,612,366 | $28.2M | 0.01% | −5,516−0.2% | Reduced |
| Goldman Sachs Group Inc | 3,212,785 | $25.1M | 0.00% | +500,979+18.5% | Added |
| Perceptive Advisors LLC | 3,162,529 | $24.7M | 0.45% | +3,162,529 | New |
| GW&K Investment Management, LLC | 3,160,924 | $24.7M | 0.21% | +963,159+43.8% | Added |
| Eversept Partners, LP | 2,992,895 | $23.3M | 1.31% | +1,619,270+117.9% | Added |
| Baker Bros. Advisors LP | 2,822,727 | $22.0M | 0.13% | +2,822,727 | New |
| BNP Paribas Arbitrage, SA | 2,542,714 | $19.8M | 0.01% | +448,436+21.4% | Added |
| Fisher Asset Management, LLC | 2,467,567 | $19.2M | 0.01% | −165,129−6.3% | Reduced |
| Vestal Point Capital, LP | 2,250,000 | $17.6M | 0.64% | +2,250,000 | New |
| Qube Research & Technologies Ltd | 2,164,162 | $16.9M | 0.02% | −246,200−10.2% | Reduced |
| Elmind Capital, LP | 2,150,000 | $16.8M | 4.95% | +2,150,000 | New |
| Renaissance Technologies LLC | 2,128,821 | $16.6M | 0.03% | −11,713−0.5% | Reduced |
| Charles Schwab Investment Management Inc | 2,004,939 | $15.6M | 0.00% | +10,535+0.5% | Added |
| Rice Hall James & Associates, LLC | 1,904,146 | $14.9M | 0.82% | +23,757+1.3% | Added |
| Northern Trust Corp | 1,856,903 | $14.5M | 0.00% | −35,140−1.9% | Reduced |
| Stifel Financial Corp | 1,824,517 | $14.2M | 0.01% | +1,525+0.1% | Added |
| Morgan Stanley | 1,745,563 | $13.6M | 0.00% | −3,457,396−66.5% | Reduced |
| OrbiMed Advisors LLC | 1,741,800 | $13.6M | 0.28% | +840,300+93.2% | Added |
| Squarepoint Ops LLC | 1,659,192 | $12.9M | 0.03% | +550,532+49.7% | Added |
| Bank of America Corp | 1,535,557 | $12.0M | 0.00% | −367,262−19.3% | Reduced |
| Nantahala Capital Management, LLC | 1,356,377 | $10.6M | 0.63% | +1,356,377 | New |
| Invesco Ltd. | 1,354,897 | $10.6M | 0.00% | +392,521+40.8% | Added |
| Citadel Advisors LLC | 1,298,902 | $10.1M | 0.01% | −60,980−4.5% | Reduced |
| D. E. Shaw & Co., Inc. | 1,247,466 | $9.73M | 0.01% | −461,870−27.0% | Reduced |
| Dimensional Fund Advisors LP | 1,228,852 | $9.59M | 0.00% | +1,228,852 | New |
| Point72 Asset Management, L.P. | 1,213,576 | $9.47M | 0.01% | +975,389+409.5% | Added |
| Jupiter Asset Management Ltd | 1,197,619 | $9.34M | 0.07% | −858,296−41.7% | Reduced |
| Jacobs Levy Equity Management, Inc | 1,031,488 | $8.05M | 0.03% | +661,025+178.4% | Added |
| Hudson Bay Capital Management LP | 1,017,374 | $7.94M | 0.05% | +1,017,374 | New |
| Standard Life Aberdeen plc | 913,593 | $7.13M | 0.01% | +913,593 | New |
| Jump Financial, LLC | 910,930 | $7.11M | 0.09% | −13,846−1.5% | Reduced |
| Parkman Healthcare Partners LLC | 900,057 | $7.02M | 0.67% | −112,607−11.1% | Reduced |
| JPMorgan Chase & Co | 843,370 | $6.58M | 0.00% | −289,007−25.5% | Reduced |
| Sphera Funds Management Ltd. | 837,889 | $6.54M | 1.37% | +837,889 | New |
| Tang Capital Management LLC | 800,000 | $6.24M | 0.31% | 00.0% | Unchanged |
| Susquehanna Portfolio Strategies, LLC | 778,521 | $6.07M | 0.09% | +778,521 | New |
| Pictet Asset Management Holding SA | 740,510 | $5.71M | 0.01% | −455,809−38.1% | Reduced |
| Barclays PLC | 726,367 | $5.67M | 0.00% | −55,865−7.1% | Reduced |
| HRT Financial LP | 716,826 | $5.59M | 0.02% | +658,920+1,137.9% | Added |
| AQR Capital Management LLC | 704,291 | $5.49M | 0.00% | −295,494−29.6% | Reduced |
| PDT Partners, LLC | 683,416 | $5.33M | 0.35% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 671,693 | $5.24M | 0.01% | +425,932+173.3% | Added |
| Jane Street Group, LLC | 649,357 | $5.06M | 0.01% | −1,198,989−64.9% | Reduced |
| Voya Investment Management LLC | 625,490 | $4.88M | 0.00% | +169,899+37.3% | Added |
| Bank of New York Mellon Corp | 607,992 | $4.74M | 0.00% | −11,996−1.9% | Reduced |
| Franklin Resources Inc | 570,189 | $4.45M | 0.00% | +104,851+22.5% | Added |
| FMR LLC | 560,182 | $4.37M | 0.00% | −93,632−14.3% | Reduced |
| Hillsdale Investment Management Inc. | 559,100 | $4.36M | 0.12% | −2,500−0.4% | Reduced |
| Deutsche Bank AG | 491,086 | $3.83M | 0.00% | −577,929−54.1% | Reduced |
| Voloridge Investment Management, LLC | 449,743 | $3.51M | 0.01% | −507,278−53.0% | Reduced |
| DAFNA Capital Management LLC | 418,255 | $3.26M | 0.76% | +200,000+91.6% | Added |
| Man Group plc | 407,850 | $3.18M | 0.01% | +53,366+15.1% | Added |
| Swiss National Bank | 394,368 | $3.08M | 0.00% | +9,000+2.3% | Added |
| Rafferty Asset Management, LLC | 382,556 | $2.98M | 0.01% | +13,234+3.6% | Added |
| UBS Asset Management Americas Inc | 378,853 | $2.96M | 0.00% | −15,887−4.0% | Reduced |
| Principal Financial Group Inc | 376,568 | $2.94M | 0.00% | +132,159+54.1% | Added |
| First Trust Advisors LP | 374,961 | $2.92M | 0.00% | −360,026−49.0% | Reduced |
| Assenagon Asset Management S.A. | 359,580 | $2.80M | 0.00% | −2,733,012−88.4% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 357,086 | $2.79M | 0.01% | −491,476−57.9% | Reduced |
| State of Wisconsin Investment Board | 347,190 | $2.71M | 0.01% | −28,661−7.6% | Reduced |
| Los Angeles Capital Management LLC | 355,055 | $2.57M | 0.01% | +45,945+14.9% | Added |
| Canada Pension Plan Investment Board | 327,941 | $2.56M | 0.00% | +97,600+42.4% | Added |
| Victory Capital Management Inc | 325,051 | $2.54M | 0.00% | +265,564+446.4% | Added |
| Ishara Investments LP | 300,000 | $2.34M | 2.72% | +300,000 | New |
| Federated Hermes, Inc. | 292,850 | $2.28M | 0.00% | +27,345+10.3% | Added |
| Alliancebernstein L.P. | 278,190 | $2.17M | 0.00% | −143−0.1% | Reduced |
| Doliver Advisors, LP | 274,328 | $2.14M | 0.54% | 00.0% | Unchanged |
| Rhumbline Advisers | 266,562 | $2.08M | 0.00% | −60,273−18.4% | Reduced |
| Hussman Strategic Advisors, Inc. | 252,000 | $1.97M | 0.48% | +42,000+20.0% | Added |
| Walleye Capital LLC | 251,670 | $1.96M | 0.01% | +24,606+10.8% | Added |
| Phocas Financial Corp. | 250,797 | $1.96M | 0.25% | +250,797 | New |
| Bridgewater Associates, LP | 235,572 | $1.84M | 0.01% | −175,931−42.8% | Reduced |
| Wells Fargo & Company | 233,639 | $1.82M | 0.00% | +100,603+75.6% | Added |
| Virginia Retirement Systems Et Al | 233,354 | $1.82M | 0.01% | +120,350+106.5% | Added |
| Russell Investments Group, Ltd. | 229,226 | $1.79M | 0.00% | −85,267−27.1% | Reduced |
| Engineers Gate Manager LP | 224,543 | $1.75M | 0.02% | −218,304−49.3% | Reduced |
| Gotham Asset Management, LLC | 216,946 | $1.69M | 0.01% | −126,825−36.9% | Reduced |
| Legal & General Group Plc | 210,999 | $1.65M | 0.00% | −15,166−6.7% | Reduced |
| Integral Health Asset Management, LLC | 200,000 | $1.56M | 0.08% | +200,000 | New |
| California State Teachers Retirement System | 191,847 | $1.50M | 0.00% | +9,381+5.1% | Added |
| Diadema Partners LP | 190,928 | $1.49M | 0.89% | +190,928 | New |
| Price T Rowe Associates Inc | 177,392 | $1.38M | 0.00% | +16,044+9.9% | Added |
| Royal Bank of Canada | 161,456 | $1.26M | 0.00% | −23,959−12.9% | Reduced |
| Mackenzie Financial Corp | 150,728 | $1.15M | 0.00% | +21,411+16.6% | Added |
| Profund Advisors LLC | 141,985 | $1.11M | 0.03% | +61,966+77.4% | Added |
| Schonfeld Strategic Advisors LLC | 141,449 | $1.10M | 0.01% | −25,392−15.2% | Reduced |
| OP Asset Management Ltd | 139,207 | $1.09M | 0.01% | +139,207 | New |
| Millennium Management LLC | 137,626 | $1.07M | 0.00% | −323,321−70.1% | Reduced |