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Biocryst Pharmaceuticals Inc

BCRX
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0000882796

No open-market purchases or sales by Biocryst Pharmaceuticals Inc insiders were filed in the last 90 days; 319 institutions reported holding it in 13F filings for Q2 2026, worth $2.61B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Biocryst Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
273
−8 vs. Q3 2025
Shares held
212.5M
+19.7M (+10.2%) vs. Q3 2025
Total value
$1.66B
+$193.5M (+13.2%) vs. Q3 2025
New holders
49
91 more added
Sold out
57
101 more reduced

5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting BCRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 273 institutions
Q1 2021: 191 institutionsQ2 2021: 195 institutionsQ3 2021: 197 institutionsQ4 2021: 206 institutionsQ1 2022: 233 institutionsQ2 2022: 221 institutionsQ3 2022: 234 institutionsQ4 2022: 230 institutionsQ1 2023: 242 institutionsQ2 2023: 236 institutionsQ3 2023: 233 institutionsQ4 2023: 236 institutionsQ1 2024: 238 institutionsQ2 2024: 242 institutionsQ3 2024: 257 institutionsQ4 2024: 258 institutionsQ1 2025: 274 institutionsQ2 2025: 294 institutionsQ3 2025: 286 institutionsQ4 2025: 273 institutionsQ1 2026: 303 institutionsQ2 2026: 319 institutions
Value heldQ4 2025: $1.66B
Q1 2021: $1.06BQ2 2021: $1.65BQ3 2021: $1.48BQ4 2021: $1.63BQ1 2022: $2.07BQ2 2022: $1.61BQ3 2022: $1.87BQ4 2022: $1.80BQ1 2023: $1.42BQ2 2023: $1.23BQ3 2023: $1.24BQ4 2023: $1.06BQ1 2024: $915.0MQ2 2024: $1.08BQ3 2024: $1.32BQ4 2024: $1.26BQ1 2025: $1.32BQ2 2025: $1.77BQ3 2025: $1.47BQ4 2025: $1.66BQ1 2026: $2.37BQ2 2026: $2.61B
Institutions holding BCRX and their total value by quarter
QuarterHoldersValue
Q2 2026319$2.61B
Q1 2026303$2.37B
Q4 2025273$1.66B
Q3 2025286$1.47B
Q2 2025294$1.77B
Q1 2025274$1.32B
Q4 2024258$1.26B
Q3 2024257$1.32B
Q2 2024242$1.08B
Q1 2024238$915.0M
Q4 2023236$1.06B
Q3 2023233$1.24B
Q2 2023236$1.23B
Q1 2023242$1.42B
Q4 2022230$1.80B
Q3 2022234$1.87B
Q2 2022221$1.61B
Q1 2022233$2.07B
Q4 2021206$1.63B
Q3 2021197$1.48B
Q2 2021195$1.65B
Q1 2021191$1.06B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Biocryst Pharmaceuticals Inc; share changes are against Q3 2025.

Institutions holding BCRX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Dunhill Financial, LLC2$180.00%+2New
Clearstead Advisors, LLC4$320.00%+4New
SJS Investment Consulting Inc.14$1100.00%+14New
SageView Advisory Group, LLC20$1560.00%+20New
SBI Securities Co., Ltd.35$2730.00%+7+25.0%Added
MAI Capital Management40$3120.00%+40New
Chilton Capital Management LLC40$3120.00%+40New
SRS Capital Advisors, Inc.46$3590.00%−2,947−98.5%Reduced
Harbour Investments, Inc.51$3980.00%00.0%Unchanged
Global Retirement Partners, LLC70$5460.00%+70New
Sound Income Strategies, LLC100$6660.00%+100New
Cornerstone Planning Group LLC100$6660.00%+52+108.3%Added
Parallel Advisors, LLC93$7250.00%−50−35.0%Reduced
Bell Investment Advisors, Inc107$8350.00%00.0%Unchanged
Torren Management, LLC111$8660.00%+111New
IFP Advisors, Inc124$9670.00%−565−82.0%Reduced
Parkside Financial Bank & Trust148$1.16K0.00%−53−26.4%Reduced
Versant Capital Management, Inc154$1.20K0.00%00.0%Unchanged
Private Trust Co NA159$1.24K0.00%00.0%Unchanged
Comerica Bank184$1.44K0.00%+36+24.3%Added
Pingora Partners LLC200$1.56K0.00%00.0%Unchanged
Rothschild Investment LLC202$1.58K0.00%−103−33.8%Reduced
Brown Brothers Harriman & Co219$1.71K0.00%00.0%Unchanged
GAMMA Investing LLC241$1.88K0.00%−104−30.1%Reduced
Bessemer Group Inc278$2.00K0.00%00.0%Unchanged
Covestor Ltd202$2.00K0.00%−1−0.5%Reduced
Flagship Harbor Advisors, LLC325$2.54K0.00%+325New
Bradley & Co. Private Wealth Management, LLC370$2.89K0.00%+370New
Independence Bank of Kentucky400$3.12K0.00%+400New
Allworth Financial LP432$3.37K0.00%−110−20.3%Reduced
Optiver Holding B.V.483$3.77K0.00%−807−62.6%Reduced
National Bank of Canada500$3.90K0.00%+500New
Farmers & Merchants Trust Co of Chambersburg PA500$4.00K0.00%00.0%Unchanged
EverSource Wealth Advisors, LLC564$4.40K0.00%−518−47.9%Reduced
Daiwa Securities Group Inc.692$5.00K0.00%00.0%Unchanged
Root Financial Partners, LLC700$5.46K0.00%00.0%Unchanged
Quadrant Capital Group LLC705$5.50K0.00%00.0%Unchanged
Aster Capital Management (DIFC) Ltd894$6.97K0.00%+894New
Smartleaf Asset Management LLC955$7.32K0.00%+17+1.8%Added
Westside Investment Management, Inc.1,000$7.80K0.00%+500+100.0%Added
Oakworth Capital, Inc.1,038$8.10K0.00%+68+7.0%Added
Sterling Capital Management LLC1,391$10.8K0.00%+883+173.8%Added
Tower Research Capital LLC (TRC)1,524$11.9K0.00%−17,080−91.8%Reduced
Activest Wealth Management2,000$15.6K0.00%00.0%Unchanged
BNP PARIBAS ASSET MANAGEMENT Holding S.A.2,168$17.0K0.00%+504+30.3%Added
Jones Financial Companies LLLP2,200$17.2K0.00%+717+48.3%Added
Nisa Investment Advisors, LLC2,557$19.9K0.00%−265−9.4%Reduced
Federation des caisses Desjardins du Quebec3,020$23.6K0.00%+626+26.1%Added
Larson Financial Group LLC3,542$27.6K0.00%+3,267+1,188.0%Added
Essential Partners LLC4,046$31.6K0.01%−997−19.8%Reduced
GF Fund Management Co. Ltd.4,137$32.3K0.00%−379−8.4%Reduced
Assetmark, Inc4,768$37.2K0.00%+1,145+31.6%Added
Signaturefd, LLC5,760$44.9K0.00%−187−3.1%Reduced
NBC Securities, Inc.6,000$46.8K0.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co6,127$47.8K0.00%−10.0%Reduced
Amalgamated Bank6,581$51.0K0.00%−574−8.0%Reduced
KBC Group NV6,947$54.0K0.00%00.0%Unchanged
Huntington National Bank7,553$58.9K0.00%+917+13.8%Added
CWM, LLC8,361$65.0K0.00%−21,525−72.0%Reduced
Bayforest Capital Ltd8,479$66.1K0.05%−61,552−87.9%Reduced
Mirae Asset Global Investments Co., Ltd.10,231$79.8K0.00%+2,115+26.1%Added
Envestnet Portfolio Solutions, Inc.10,430$81.4K0.00%+10,430New
Farther Finance Advisors, LLC11,492$89.6K0.00%+902+8.5%Added
State of Alaska, Department of Revenue11,899$92.0K0.00%00.0%Unchanged
Vestmark Advisory Solutions, Inc.12,123$94.6K0.00%+1,395+13.0%Added
Mount Yale Investment Advisors, LLC12,123$94.6K0.00%+1,395+13.0%Added
Cetera Investment Advisers12,330$96.2K0.00%+1,494+13.8%Added
DRW Securities, LLC12,397$96.7K0.01%−92,919−88.2%Reduced
EntryPoint Capital, LLC12,691$99.0K0.04%−29,623−70.0%Reduced
Pinnacle Wealth Planning Services, Inc.12,778$99.7K0.01%00.0%Unchanged
Prudential Financial Inc12,790$99.8K0.00%−381,775−96.8%Reduced
Kestra Advisory Services, LLC13,060$101.9K0.00%−72−0.5%Reduced
Quantessence Capital LLC13,200$103.0K1.19%+13,200New
RSM US Wealth Management LLC13,764$105.4K0.00%+20+0.1%Added
Inceptionr LLC13,631$106.3K0.03%+2,317+20.5%Added
Steel Peak Wealth Management LLC13,690$106.8K0.00%+13,690New
CIBC World Markets Corp13,858$108.1K0.00%+13,858New
Atria Investments LLC14,092$109.9K0.00%+1,863+15.2%Added
Ensign Peak Advisors, Inc14,400$112.3K0.00%−32,400−69.2%Reduced
Stratos Wealth Partners, LTD.14,700$114.7K0.00%+14,700New
Wealth Enhancement Advisory Services, LLC16,018$121.4K0.00%−5,806−26.6%Reduced
Winton Group Ltd15,600$121.7K0.00%+15,600New
XTX Topco Ltd17,111$133.5K0.00%+17,111New
Great West Life Assurance Co17,374$136.0K0.00%−43,532−71.5%Reduced
Ameritas Investment Partners, Inc.17,500$136.5K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.17,715$138.2K0.00%+800+4.7%Added
Captrust Financial Advisors17,740$138.4K0.00%−1,839−9.4%Reduced
HighTower Advisors, LLC18,030$140.6K0.00%+930+5.4%Added
Skopos Labs, Inc.18,708$144.2K0.01%+18,708New
Banco Bilbao Vizcaya Argentaria, S.A.19,249$147.8K0.00%+19,249New
Cambridge Investment Research Advisors, Inc.19,473$152.0K0.00%−2,961−13.2%Reduced
Cypress Wealth Services, LLC20,000$156.0K0.02%00.0%Unchanged
Visionary Wealth Advisors20,090$156.7K0.01%00.0%Unchanged
Navellier & Associates Inc21,903$170.8K0.02%−44,967−67.2%Reduced
Xponance, Inc.22,258$173.6K0.00%+94+0.4%Added
Quantinno Capital Management LP23,152$180.6K0.00%−6,369−21.6%Reduced
Twinbeech Capital LP23,700$184.9K0.01%−172,037−87.9%Reduced
Walleye Trading LLC23,777$185.5K0.00%+23,777New
Legato Capital Management LLC23,949$186.8K0.02%+2,172+10.0%Added
Farallon Capital Management, L.L.C.24,000$187.2K0.00%00.0%Unchanged