| May 19, 2026 (view filing) | May 18 | 1 day | McKee Amy EDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −11.2K | $8.97 | −$100.3K | −26.3%31.3K after | |
| May 15, 2026 (view filing) | May 13 | 2 days | Barnes Alane PChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −62.5K | $9.54 | −$596.3K | −13.5%400.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 24, 2026 (view filing) | Mar 20 | 4 days | Heggie TheresaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −49.9K | $10.11 | −$504.8K | −43.3%65.4K after | |
| Mar 18, 2026 (view filing) | Mar 16 | 2 days | Barnes Alane PChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −150.0K | $9.15 | −$1.37M | −27.2%400.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 23, 2025 (view filing) | Dec 22 | 1 day | Barnes Alane PChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −21.8K | $7.65 | −$166.6K | −5.2%398.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 16, 2025 (view filing) | Dec 15 | 1 day | Barnes Alane PChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −21.2K | $7.65 | −$162.3K | −6.3%315.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 3, 2025 (view filing) | Dec 1-3 | 2 days | Barnes Alane PChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −161.7K | $7.20 | −$1.16M | −31.9%345.5K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 17, 2025 (view filing) | Nov 13 | 4 days | Sanders MachelleDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.60K | $7.14 | −$68.5K | −23.9%30.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 15, 2025 (view filing) | Aug 13 | 2 days | Heggie TheresaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −70.0K | $8.51 | −$595.7K | −51.7%65.4K after | |
| Dec 16, 2024 (view filing) | Dec 13 | 3 days | Hutson Nancy JDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.00K | $7.54 | −$52.8K | −7.5%86.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 25, 2024 (view filing) | Jun 24 | 1 day | McKee Amy EDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.60K | $6.32 | −$54.4K | −23.6%27.8K after | |
| Jun 17, 2024 (view filing) | Jun 17 | Same day | Sanders MachelleDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.69K | $6.00 | −$28.1K | −14.5%27.7K after | |
| Jun 14, 2024 (view filing) | Jun 14 | Same day | Heggie TheresaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.70K | $6.11 | −$40.9K | −11.2%52.9K after | |
| May 31, 2024 (view filing) | May 30 | 1 day | Levin Alan GDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +7.86K | $6.36 | +$50.0K | +21.2%45.0K after | |
| May 29, 2024 (view filing) | May 24 | 5 days | Aselage SteveDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +2.50K | $6.40 | +$16.0K | New position2.50K after | |
| May 22, 2024 (view filing) | May 20 | 2 days | Hutson Nancy JDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +5.00K | $6.38 | +$31.9K | +6.1%86.8K after | |
| May 22, 2024 (view filing) | May 20 | 2 days | Milano VincentDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +15.0K | $6.25 | +$93.8K | +28.8%67.0K after | |
| May 15, 2024 (view filing) | May 14 | 1 day | Doyle AnthonyChief Financial Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +36.3K | $5.57 | +$202.2K | +15.8%266.7K after | |
| May 15, 2024 (view filing) | May 14 | 1 day | Thackray Helen M.Chief R&D Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +30.0K | $5.86 | +$175.8K | +12.4%272.1K after | |
| May 15, 2024 (view filing) | May 13 | 2 days | Galson Steven KDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +21.9K | $5.49 | +$120.5K | +74.1%51.6K after | |
| May 15, 2024 (view filing) | May 13 | 2 days | Barnes Alane PChief Legal Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +5.00K | $5.53 | +$27.6K | +1.7%300.8K after | |
| May 15, 2024 (view filing) | May 13 | 2 days | Stonehouse Jon PPresident & CEO | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +30.0K | $5.55 | +$166.5K | +2.7%1.13M after | |
| May 15, 2024 (view filing) | May 13 | 2 days | Gayer Charles KChief Commercial Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +30.0K | $5.47 | +$164.1K | +10.8%307.5K after | |
| Jun 15, 2023 (view filing) | Jun 15 | Same day | Sanders MachelleDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.00K | $7.98 | −$31.9K | −13.5%25.6K after | |
| Jun 15, 2023 (view filing) | Jun 14 | 1 day | Hutson Nancy JDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −12.9K | $8.04 | −$103.4K | −13.6%81.8K after | |
| Apr 5, 2023 (view filing) | Apr 3 | 2 days | Thackray Helen M.Chief R&D Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.00K | $8.29 | −$58.0K | −3.3%207.3K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 2, 2023 (view filing) | Feb 1 | 1 day | Stonehouse Jon PPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −100.0K | $10.38 | −$1.04M | −9.0%1.01M after | |
| Dec 19, 2022 (view filing) | Dec 15 | 4 days | Stonehouse Jon PPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −14.1K | $10.90 | −$153.7K | −1.6%887.7K after | |
| Dec 19, 2022 (view filing) | Dec 15 | 4 days | Thackray Helen M.Chief R&D Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.13K | $10.89 | −$34.0K | −2.3%133.3K after | |
| Dec 19, 2022 (view filing) | Dec 15 | 4 days | Doyle AnthonyChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.70K | $10.90 | −$62.1K | −3.4%164.0K after | |
| Dec 19, 2022 (view filing) | Dec 15 | 4 days | Gayer Charles KChief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.10K | $10.90 | −$66.5K | −2.8%211.6K after | |
| Dec 19, 2022 (view filing) | Dec 15 | 4 days | Jones Michael LExec. Director, Finance - PAO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −445 | $10.90 | −$4.85K | −4.0%10.8K after | |
| Dec 19, 2022 (view filing) | Dec 15 | 4 days | Barnes Alane PChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.17K | $10.88 | −$45.4K | −2.1%198.8K after | |
| Dec 2, 2022 (view filing) | Dec 1 | 1 day | Jones Michael LExec. Director, Finance - PAO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.60K | $13.01 | −$111.9K | −43.4%11.2K after | |
| Dec 2, 2022 (view filing) | Dec 1-2 | 1 day | Stonehouse Jon PPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −297.6K | $12.94 | −$3.85M | −24.8%901.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Nov 16, 2022 (view filing) | Nov 14 | 2 days | Babu Yarlagadda SChief Discovery Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −31.5K | $13.88 | −$437.4K | −9.5%298.5K after | |
| Apr 20, 2022 (view filing) | Apr 18 | 2 days | Abercrombie George BDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $11.04 | −$55.2K | −100.0%0 after | |
| Apr 4, 2022 (view filing) | Apr 1 | 3 days | Thackray Helen M.Chief R&D Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.60K | $16.20 | −$123.1K | −5.3%136.4K after | |
| Mar 14, 2022 (view filing) | Mar 10 | 4 days | Sheridan William PChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −161.1K | $16.88 | −$2.72M | −80.9%38.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 9, 2022 (view filing) | Mar 7 | 2 days | Babu Yarlagadda SChief Discovery Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −20.0K | $17.16 | −$343.2K | −8.0%230.1K after | |
| Mar 3, 2022 (view filing) | Mar 1 | 2 days | Jones Michael LExec. Director, Finance - PAO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.30K | $17.20 | −$39.6K | −17.0%11.2K after | |
| Feb 16, 2022 (view filing) | Feb 15 | 1 day | Abercrombie George BDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $18.50 | −$92.5K | −100.0%0 after | |
| Jan 13, 2022 (view filing) | Jan 11 | 2 days | Stonehouse Jon PPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −184.0K | $15.04 | −$2.77M | −16.9%901.6K after | |
| Dec 9, 2021 (view filing) | Dec 7 | 2 days | Babu Yarlagadda SChief Discovery Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −30.1K | $12.20 | −$367.2K | −12.3%215.1K after | |
| Nov 24, 2021 (view filing) | Nov 24 | Same day | Milano VincentDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +7.50K | $12.19 | +$91.4K | +75.0%17.5K after | |
| Nov 24, 2021 (view filing) | Nov 23 | 1 day | Doyle AnthonyChief Financial Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +35.3K | $12.48 | +$440.0K | +60.3%93.7K after | |
| Nov 17, 2021 (view filing) | Nov 15 | 2 days | Abercrombie George BDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $12.27 | −$61.4K | −100.0%0 after | |
| Oct 19, 2021 (view filing) | Oct 15 | 4 days | Hutson Nancy JDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −105.0K | $15.40 | −$1.62M | −61.7%65.1K after | |
| Sep 17, 2021 (view filing) | Sep 15 | 2 days | Abercrombie George BDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $15.06 | −$75.3K | −100.0%0 after | |
| Sep 15, 2021 (view filing) | Sep 13 | 2 days | Lee Kenneth B JrDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.00K | $15.35 | −$92.1K | −19.8%24.3K after | |
