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Biocryst Pharmaceuticals Inc

BCRX
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0000882796

No open-market purchases or sales by Biocryst Pharmaceuticals Inc insiders were filed in the last 90 days; 319 institutions reported holding it in 13F filings for Q2 2026, worth $2.61B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Biocryst Pharmaceuticals Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
286
−3 vs. Q2 2025
Shares held
194.2M
−2.78M (−1.4%) vs. Q2 2025
Total value
$1.47B
−$291.6M (−16.5%) vs. Q2 2025
New holders
37
94 more added
Sold out
40
107 more reduced

5 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting BCRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 286 institutions
Q1 2021: 191 institutionsQ2 2021: 195 institutionsQ3 2021: 197 institutionsQ4 2021: 206 institutionsQ1 2022: 233 institutionsQ2 2022: 221 institutionsQ3 2022: 234 institutionsQ4 2022: 230 institutionsQ1 2023: 242 institutionsQ2 2023: 236 institutionsQ3 2023: 233 institutionsQ4 2023: 236 institutionsQ1 2024: 238 institutionsQ2 2024: 242 institutionsQ3 2024: 257 institutionsQ4 2024: 258 institutionsQ1 2025: 274 institutionsQ2 2025: 294 institutionsQ3 2025: 286 institutionsQ4 2025: 273 institutionsQ1 2026: 303 institutionsQ2 2026: 319 institutions
Value heldQ3 2025: $1.47B
Q1 2021: $1.06BQ2 2021: $1.65BQ3 2021: $1.48BQ4 2021: $1.63BQ1 2022: $2.07BQ2 2022: $1.61BQ3 2022: $1.87BQ4 2022: $1.80BQ1 2023: $1.42BQ2 2023: $1.23BQ3 2023: $1.24BQ4 2023: $1.06BQ1 2024: $915.0MQ2 2024: $1.08BQ3 2024: $1.32BQ4 2024: $1.26BQ1 2025: $1.32BQ2 2025: $1.77BQ3 2025: $1.47BQ4 2025: $1.66BQ1 2026: $2.37BQ2 2026: $2.61B
Institutions holding BCRX and their total value by quarter
QuarterHoldersValue
Q2 2026319$2.61B
Q1 2026303$2.37B
Q4 2025273$1.66B
Q3 2025286$1.47B
Q2 2025294$1.77B
Q1 2025274$1.32B
Q4 2024258$1.26B
Q3 2024257$1.32B
Q2 2024242$1.08B
Q1 2024238$915.0M
Q4 2023236$1.06B
Q3 2023233$1.24B
Q2 2023236$1.23B
Q1 2023242$1.42B
Q4 2022230$1.80B
Q3 2022234$1.87B
Q2 2022221$1.61B
Q1 2022233$2.07B
Q4 2021206$1.63B
Q3 2021197$1.48B
Q2 2021195$1.65B
Q1 2021191$1.06B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Biocryst Pharmaceuticals Inc; share changes are against Q2 2025.

Institutions holding BCRX in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Vanguard Group Inc21,790,881$165.4M0.00%+1,246,633+6.1%Added
BlackRock, Inc.21,245,876$161.3M0.00%−179,973−0.8%Reduced
Deerfield Management Company, L.P. (Series C)12,169,000$92.4M1.42%+7,477,000+159.4%Added
State Street Corp9,807,438$74.4M0.00%+1,302,046+15.3%Added
Kynam Capital Management, LP9,390,270$71.3M5.31%+926,528+10.9%Added
UBS Group AG5,967,737$45.3M0.01%+353,086+6.3%Added
Alkeon Capital Management LLC5,464,021$41.5M0.19%−250,000−4.4%Reduced
Arrowstreet Capital, Limited Partnership5,225,986$39.7M0.03%+947,431+22.1%Added
Morgan Stanley5,202,959$39.5M0.00%−126,720−2.4%Reduced
Geode Capital Management, LLC5,052,307$38.4M0.00%−2,3030.0%Reduced
Two Sigma Investments, LP4,419,629$33.5M0.05%+131,406+3.1%Added
Two Sigma Advisers, LP4,240,712$32.2M0.06%+12,300+0.3%Added
Hood River Capital Management LLC3,620,261$27.5M0.32%+2,376,327+191.0%Added
Nuveen, LLC3,617,882$27.5M0.01%+83,428+2.4%Added
Assenagon Asset Management S.A.3,092,592$23.5M0.03%−528,045−14.6%Reduced
Goldman Sachs Group Inc2,711,806$20.6M0.00%−812,111−23.0%Reduced
Fisher Asset Management, LLC2,632,696$20.0M0.01%−149,793−5.4%Reduced
Qube Research & Technologies Ltd2,410,362$18.3M0.03%+36,873+1.6%Added
GW&K Investment Management, LLC2,197,765$16.7M0.15%−425,772−16.2%Reduced
Renaissance Technologies LLC2,140,534$16.2M0.02%−386,200−15.3%Reduced
BNP Paribas Arbitrage, SA2,094,278$15.9M0.01%+637,421+43.8%Added
Jupiter Asset Management Ltd2,055,915$15.6M0.13%−22,051−1.1%Reduced
Charles Schwab Investment Management Inc1,994,404$15.1M0.00%+24,529+1.2%Added
Bank of America Corp1,902,819$14.4M0.00%−938,336−33.0%Reduced
Northern Trust Corp1,892,043$14.4M0.00%−21,686−1.1%Reduced
Rice Hall James & Associates, LLC1,880,389$14.3M0.78%−179,891−8.7%Reduced
Jane Street Group, LLC1,848,346$14.0M0.02%+1,569,848+563.7%Added
Stifel Financial Corp1,822,992$13.8M0.01%−2960.0%Reduced
D. E. Shaw & Co., Inc.1,709,336$13.0M0.01%−2,680,141−61.1%Reduced
Eversept Partners, LP1,373,625$10.4M0.80%+165,987+13.7%Added
Citadel Advisors LLC1,359,882$10.3M0.01%−1,197,550−46.8%Reduced
Avoro Capital Advisors LLC1,250,000$9.49M0.12%−3,250,000−72.2%Reduced
Cubist Systematic Strategies, LLC1,246,696$9.46M0.13%+1,246,696New
Pictet Asset Management Holding SA1,196,319$9.03M0.01%+227,278+23.5%Added
Segall Bryant & Hamill, LLC1,134,813$8.61M0.11%−85,264−7.0%Reduced
JPMorgan Chase & Co1,132,377$8.59M0.00%−451,829−28.5%Reduced
Squarepoint Ops LLC1,108,660$8.41M0.02%+385,339+53.3%Added
Deutsche Bank AG1,069,015$8.11M0.00%+603,184+129.5%Added
Parkman Healthcare Partners LLC1,012,664$7.69M0.84%+4,672+0.5%Added
AQR Capital Management LLC999,785$7.59M0.00%−149,009−13.0%Reduced
Invesco Ltd.962,376$7.30M0.00%−30,741−3.1%Reduced
Voloridge Investment Management, LLC957,021$7.26M0.02%−1,517,054−61.3%Reduced
Jump Financial, LLC924,776$7.02M0.09%−422,336−31.4%Reduced
OrbiMed Advisors LLC901,500$6.84M0.16%+901,500New
Connor, Clark & Lunn Investment Management Ltd.848,562$6.44M0.02%−409,129−32.5%Reduced
Acadian Asset Management LLC839,403$6.36M0.01%+467,631+125.8%Added
Tang Capital Management LLC800,000$6.07M0.23%00.0%Unchanged
Barclays PLC782,232$5.94M0.00%−21,880−2.7%Reduced
First Trust Advisors LP734,987$5.58M0.00%+7,517+1.0%Added
Marshall Wace, LLP731,411$5.55M0.01%+588,099+410.4%Added
Algert Global LLC713,088$5.41M0.09%−289,722−28.9%Reduced
PDT Partners, LLC683,416$5.19M0.33%00.0%Unchanged
FMR LLC653,814$4.96M0.00%−2,079−0.3%Reduced
Bank of New York Mellon Corp619,988$4.71M0.00%+7,330+1.2%Added
Hillsdale Investment Management Inc.561,600$4.26M0.13%+25,600+4.8%Added
Schroder Investment Management Group535,968$4.05M0.00%+535,968New
Franklin Resources Inc465,338$3.53M0.00%+71,453+18.1%Added
Millennium Management LLC460,947$3.50M0.00%−1,445,720−75.8%Reduced
Voya Investment Management LLC455,591$3.46M0.00%−25,210−5.2%Reduced
Engineers Gate Manager LP442,847$3.36M0.04%+301,341+213.0%Added
Y-Intercept (Hong Kong) Ltd434,531$3.30M0.08%+98,436+29.3%Added
Bridgewater Associates, LP411,503$3.12M0.01%+411,503New
UBS Asset Management Americas Inc394,740$3.00M0.00%−297,229−43.0%Reduced
Prudential Financial Inc394,565$2.99M0.00%−34,770−8.1%Reduced
Swiss National Bank385,368$2.92M0.00%+6,100+1.6%Added
State of Wisconsin Investment Board375,851$2.85M0.01%+602+0.2%Added
Jacobs Levy Equity Management, Inc370,463$2.81M0.01%−11,017−2.9%Reduced
Rafferty Asset Management, LLC369,322$2.80M0.01%+68,371+22.7%Added
ExodusPoint Capital Management, LP364,457$2.77M0.04%+153,617+72.9%Added
SEI Investments Co362,216$2.75M0.00%+138,973+62.3%Added
Man Group plc354,484$2.69M0.01%−67,286−16.0%Reduced
Gotham Asset Management, LLC343,771$2.61M0.01%+141,958+70.3%Added
Rhumbline Advisers326,835$2.48M0.00%−10,104−3.0%Reduced
Brevan Howard Capital Management LP325,795$2.47M0.04%+187,491+135.6%Added
Russell Investments Group, Ltd.314,493$2.39M0.00%−125,756−28.6%Reduced
Los Angeles Capital Management LLC309,110$2.35M0.01%+210,064+212.1%Added
Alliancebernstein L.P.278,333$2.11M0.00%+2,943+1.1%Added
Doliver Advisors, LP274,328$2.08M0.54%00.0%Unchanged
Graham Capital Management, L.P.267,730$2.03M0.08%+48,646+22.2%Added
Federated Hermes, Inc.265,505$2.02M0.00%−32,696−11.0%Reduced
Public Sector Pension Investment Board264,800$2.01M0.01%+264,800New
Jefferies Financial Group Inc.262,465$1.99M0.02%+95,888+57.6%Added
Susquehanna International Group, LLP245,761$1.87M0.00%−158,770−39.2%Reduced
Principal Financial Group Inc244,409$1.86M0.00%+56,213+29.9%Added
Point72 Asset Management, L.P.238,187$1.81M0.00%+238,187New
Canada Pension Plan Investment Board230,341$1.75M0.00%−280,000−54.9%Reduced
SG Americas Securities, LLC228,895$1.74M0.01%−6,637−2.8%Reduced
Walleye Capital LLC227,064$1.72M0.01%−2,073,564−90.1%Reduced
Legal & General Group Plc226,165$1.72M0.00%−978,318−81.2%Reduced
DAFNA Capital Management LLC218,255$1.66M0.41%00.0%Unchanged
Hussman Strategic Advisors, Inc.210,000$1.59M0.35%00.0%Unchanged
Twinbeech Capital LP195,737$1.49M0.06%+195,737New
Gsa Capital Partners LLP190,294$1.44M0.12%+78,827+70.7%Added
Royal Bank of Canada185,415$1.41M0.00%−37,175−16.7%Reduced
California State Teachers Retirement System182,466$1.38M0.00%+100.0%Added
Schonfeld Strategic Advisors LLC166,841$1.27M0.01%−586,143−77.8%Reduced
Price T Rowe Associates Inc161,348$1.23M0.00%+14,709+10.0%Added
QTR Family Wealth, LLC157,137$1.19M0.57%+5,151+3.4%Added
Wells Fargo & Company133,036$1.01M0.00%−151,895−53.3%Reduced
Massachusetts Financial Services Co131,711$999.7K0.00%+8,663+7.0%Added