Knott David M Jr
- SEC CIK
- 0001892770
- Latest filing
- Aug 12, 2026
Holdings in Q4 2025
Holdings as of Dec 31, 2025, filed Feb 12, 2026. Long positions only; changes compare share counts with Q3 2025.
- Positions
- 87
- 0 vs. Q3 2025
- Portfolio value
- $215.9M
- −$22.8M (−9.5%) vs. Q3 2025
| Security | Class | Shares | Value | % of portfolio | Share change | Action | History |
|---|---|---|---|---|---|---|---|
| CLMTCalumet, Inc. | COM | 2,214,969 | $44.0M | 20.4% | −610,262−21.6% | Reduced | History |
| APOApollo Global Management, Inc. | COM | 225,000 | $32.6M | 15.1% | 00.0% | Unchanged | History |
| GOOGAlphabet Inc. | Stock | 91,420 | $28.7M | 13.3% | −20,800−18.5% | Reduced | History |
| SNDXSyndax Pharmaceuticals Inc | COM | 415,000 | $8.72M | 4.0% | −13,000−3.0% | Reduced | History |
| XERSXeris Biopharma Holdings, Inc. | COM | 970,000 | $7.61M | 3.5% | −45,000−4.4% | Reduced | History |
| TVTXTravere Therapeutics, Inc. | COM | 186,000 | $7.11M | 3.3% | −74,000−28.5% | Reduced | History |
| BBIOBridgeBio Pharma, Inc. | COM | 85,000 | $6.50M | 3.0% | 00.0% | Unchanged | History |
| PTGXProtagonist Therapeutics, Inc | COM | 73,000 | $6.38M | 3.0% | −10,000−12.0% | Reduced | History |
| JPMJPMorgan Chase & Co | Stock | 19,477 | $6.28M | 2.9% | −897−4.4% | Reduced | History |
| Janus Detroit STR Tr47103U845 | HENDRSON AAA CL | 93,528 | $4.73M | 2.2% | −344,226−78.6% | Reduced | – |
| VRDNViridian Therapeutics, Inc. | COM | 145,000 | $4.51M | 2.1% | +28,426+24.4% | Added | History |
| CPRXCatalyst Pharmaceuticals, Inc. | COM | 189,000 | $4.41M | 2.0% | 00.0% | Unchanged | History |
| COGTCogent Biosciences, Inc. | COM | 102,000 | $3.62M | 1.7% | +102,000 | New | History |
| RCUSArcus Biosciences, Inc. | COM | 121,241 | $2.89M | 1.3% | +26,041+27.4% | Added | History |
| ALKSAlkermes plc. | SHS | 95,000 | $2.66M | 1.2% | +75,700+392.2% | Added | History |
| DCGODocGo Inc. | COM | 2,670,850 | $2.34M | 1.1% | −400,000−13.0% | Reduced | History |
| HELPCybin Inc. | COM NEW | 285,182 | $2.33M | 1.1% | +144,940+103.3% | Added | History |
| CYTKCytokinetics Inc | COM NEW | 34,000 | $2.16M | 1.0% | +4,000+13.3% | Added | History |
| ATRCAtriCure, Inc. | COM | 51,400 | $2.03M | 0.9% | +3,400+7.1% | Added | History |
| ABAlliancebernstein Holding L.P. | UNIT LTD PARTN | 48,000 | $1.85M | 0.9% | 00.0% | Unchanged | History |
| ACLXArcellx, Inc. | COMMON STOCK | 25,700 | $1.68M | 0.8% | 00.0% | Unchanged | History |
| State Street SPDR S&P Biotech ETF78464A870 | ETF | 13,000 | $1.59M | 0.7% | +8,000+160.0% | Added | – |
| TECXTectonic Therapeutic, Inc. | COM | 74,000 | $1.54M | 0.7% | 00.0% | Unchanged | History |
| WVEWave Life Sciences, Inc. | SHS | 90,000 | $1.53M | 0.7% | 00.0% | Unchanged | History |
| JNJJohnson & Johnson | Stock | 6,922 | $1.43M | 0.7% | 00.0% | Unchanged | History |
| TGTXTG Therapeutics, Inc. | COM | 45,000 | $1.34M | 0.6% | +45,000 | New | History |
| VERAVera Therapeutics, Inc. | CL A | 26,000 | $1.32M | 0.6% | 00.0% | Unchanged | History |
| Series Portfolios Tr81752T528 | ELDRIDGE BBB B | 47,807 | $1.27M | 0.6% | 00.0% | Unchanged | – |
| BHVNBiohaven Ltd. | COM | 110,720 | $1.25M | 0.6% | +110,720 | New | History |
| BMYBristol Myers Squibb Co | Stock | 22,000 | $1.19M | 0.5% | −5,000−18.5% | Reduced | History |
| MDGLMadrigal Pharmaceuticals, Inc. | COM | 2,000 | $1.16M | 0.5% | 00.0% | Unchanged | History |
| ADMAAdma Biologics, Inc. | COM | 60,200 | $1.10M | 0.5% | +60,200 | New | History |
| BIIBBiogen Inc. | COM | 6,000 | $1.06M | 0.5% | +4,000+200.0% | Added | History |
| OBIOOrchestra BioMed Holdings, Inc. | COM | 250,000 | $1.04M | 0.5% | +55,000+28.2% | Added | History |
| iShares Tr464287556 | ISHARES BIOTECH | 5,500 | $928.2K | 0.4% | +1,000+22.2% | Added | – |
| SLDBSolid Biosciences Inc. | COM NEW | 162,440 | $916.2K | 0.4% | 00.0% | Unchanged | History |
| LENZLENZ Therapeutics, Inc. | COM | 53,732 | $859.7K | 0.4% | −28,268−34.5% | Reduced | History |
| PFEPfizer Inc | Stock | 32,337 | $805.2K | 0.4% | −42,200−56.6% | Reduced | History |
| RZLTRezolute, Inc. | COM NEW | 340,000 | $802.4K | 0.4% | +65,000+23.6% | Added | History |
| MSFTMicrosoft Corp | Stock | 1,600 | $773.8K | 0.4% | 00.0% | Unchanged | History |
| AAPLApple Inc. | Stock | 2,494 | $678.0K | 0.3% | 00.0% | Unchanged | History |
| EOLSEvolus, Inc. | COM | 99,338 | $660.6K | 0.3% | +99,338 | New | History |
| NKTRNektar Therapeutics | COM NEW | 15,500 | $655.3K | 0.3% | +15,500 | New | History |
| IBMInternational Business Machines Corp | Stock | 2,142 | $634.5K | 0.3% | 00.0% | Unchanged | History |
| SRRKScholar Rock Holding Corp | COM | 13,913 | $612.9K | 0.3% | +4,913+54.6% | Added | History |
| PTHSPelthos Therapeutics Inc. | COM SHS | 19,281 | $597.7K | 0.3% | +13,169+215.5% | Added | History |
| CNQCanadian Natural Resources Ltd | COM | 16,800 | $568.7K | 0.3% | 00.0% | Unchanged | History |
| CNTBConnect Biopharma Holdings Ltd | SHS | 200,000 | $564.0K | 0.3% | +200,000 | New | History |
| XENEXenon Pharmaceuticals Inc. | COM | 10,962 | $491.3K | 0.2% | 00.0% | Unchanged | History |
| AGIOAgios Pharmaceuticals, Inc. | COM | 18,000 | $490.0K | 0.2% | +18,000 | New | History |
| RAREUltragenyx Pharmaceutical Inc. | COM | 20,006 | $460.1K | 0.2% | −31,994−61.5% | Reduced | History |
| MRSNMersana Therapeutics, Inc. | COMMON STOCK | 111,686 | $437.8K | 0.2% | +111,686 | New | History |
| KURAKura Oncology, Inc. | COM | 39,209 | $407.4K | 0.2% | −28,093−41.7% | Reduced | History |
| FATEFate Therapeutics Inc | COM | 365,000 | $358.6K | 0.2% | 00.0% | Unchanged | History |
| JSPRJasper Therapeutics, Inc. | COM NEW | 181,389 | $331.9K | 0.2% | +10,000+5.8% | Added | History |
| IVVDInvivyd, Inc. | COM | 100,000 | $247.0K | 0.1% | 00.0% | Unchanged | History |
| AVGOBroadcom Inc. | Stock | 710 | $245.7K | 0.1% | 00.0% | Unchanged | History |
| KMBKimberly Clark Corp | Stock | 2,400 | $242.1K | 0.1% | −3,600−60.0% | Reduced | History |
| DAWNDay One Biopharmaceuticals, Inc. | Stock | 25,884 | $241.2K | 0.1% | −104,616−80.2% | Reduced | History |
| NVDANVIDIA Corp | Stock | 1,280 | $238.7K | 0.1% | 00.0% | Unchanged | History |
| RHPRyman Hospitality Properties, Inc. | COM | 2,400 | $227.1K | 0.1% | −9,600−80.0% | Reduced | History |
| MDLZMondelez International, Inc. | Stock | 3,000 | $161.4K | 0.1% | −5,000−62.5% | Reduced | History |
| DDDuPont de Nemours, Inc. | COM | 3,767 | $151.4K | 0.1% | −5,651−60.0% | Reduced | History |
| MREOMereo BioPharma Group plc | SPON ADS | 300,337 | $125.2K | 0.1% | 00.0% | Unchanged | History |
| CNTACentessa Pharmaceuticals plc | SPONSORED ADS | 4,000 | $100.0K | <0.1% | +4,000 | New | History |
| QUREuniQure N.V. | SHS | 4,000 | $95.7K | <0.1% | +2,000+100.0% | Added | History |
| iShares Russell Mid-Cap Growth ETF464287481 | ETF | 695 | $95.2K | <0.1% | +695 | New | – |
| GOOGLAlphabet Inc. | Stock | 300 | $93.9K | <0.1% | 00.0% | Unchanged | History |
| EBCEastern Bankshares, Inc. | COM | 5,000 | $92.2K | <0.1% | 00.0% | Unchanged | History |
| CTVACorteva, Inc. | Stock | 1,206 | $80.8K | <0.1% | −9,845−89.1% | Reduced | History |
| LEGHLegacy Housing Corp | COM | 4,000 | $78.1K | <0.1% | 00.0% | Unchanged | History |
| PWRQuanta Services, Inc. | COM | 176 | $74.3K | <0.1% | 00.0% | Unchanged | History |
| AMZNAmazon Com Inc | Stock | 300 | $69.2K | <0.1% | 00.0% | Unchanged | History |
| URIUnited Rentals, Inc. | COM | 78 | $63.1K | <0.1% | 00.0% | Unchanged | History |
| FSKFS KKR Capital Corp | COM | 2,875 | $42.6K | <0.1% | +2,875 | New | History |
| DHRDanaher Corp | Stock | 180 | $41.2K | <0.1% | 00.0% | Unchanged | History |
| Intl Game Tech PLC Com459902102 | Equity | 2,500 | $38.7K | <0.1% | +2,500 | New | – |
| BXBlackstone Inc. | COM | 210 | $32.4K | <0.1% | 00.0% | Unchanged | History |
| DOWDow Inc. | Stock | 1,206 | $28.2K | <0.1% | 00.0% | Unchanged | History |
| TMOThermo Fisher Scientific Inc. | Stock | 45 | $26.1K | <0.1% | 00.0% | Unchanged | History |
| OXYOccidental Petroleum Corp | Stock | 663 | $23.6K | <0.1% | 00.0% | Unchanged | History |
| CRMSalesforce, Inc. | Stock | 77 | $20.4K | <0.1% | 00.0% | Unchanged | History |
| UNHUnitedHealth Group Inc | Stock | 57 | $18.8K | <0.1% | 00.0% | Unchanged | History |
| KDKyndryl Holdings, Inc. | Stock | 428 | $11.4K | <0.1% | 00.0% | Unchanged | History |
| STWDStarwood Property Trust, Inc. | COM | 400 | $7.20K | <0.1% | 00.0% | Unchanged | History |
| GEHCGE HealthCare Technologies Inc. | Stock | 50 | $4.10K | <0.1% | 00.0% | Unchanged | History |
| WABWestinghouse Air Brake Technologies Corp | Stock | 6 | $1.28K | <0.1% | 00.0% | Unchanged | History |
Sold out since Q3 2025 (13)
Positions held at the end of Q3 2025 that are gone from this filing.
| Security | Class | Shares in Q3 2025 | Value in Q3 2025 | % of portfolio in Q3 2025 | History |
|---|---|---|---|---|---|
| AVDLAvadel Pharmaceuticals PLC | Stock | 363,000 | $5.54M | 2.3% | History |
| VRNAVerona Pharma plc | SPONSORED ADS | 38,355 | $4.09M | 1.7% | History |
| CSXCSX Corp | Stock | 70,000 | $2.48M | 1.0% | History |
| LQDALiquidia Corp | COM NEW | 107,783 | $2.45M | 1.0% | History |
| PRAXPraxis Precision Medicines, Inc. | COM NEW | 28,000 | $1.48M | 0.6% | History |
| ABBVAbbVie Inc. | Stock | 5,037 | $1.17M | 0.5% | History |
| BCRXBiocryst Pharmaceuticals Inc | COM | 32,570 | $247.2K | 0.1% | History |
| LLYEli Lilly & Co | Stock | 300 | $228.9K | 0.1% | History |
| iShares Russell Midcap ETF464287499 | ETF | 695 | $99.0K | <0.1% | – |
| TTETotalEnergies SE | SPONSORED ADS | 1,200 | $71.6K | <0.1% | History |
| BRSLBrightstar Lottery PLC | SHS USD | 2,500 | $43.1K | <0.1% | History |
| FSKFS KKR Capital Corp | COM | 2,875 | $42.9K | <0.1% | History |
| Arc Resources Ltd00208D408 | COM | 1,110 | $20.2K | <0.1% | – |