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Knott David M Jr

SEC CIK
0001892770
Latest filing
Aug 12, 2026

Holdings in Q1 2026

Holdings as of Mar 31, 2026, filed May 14, 2026. Long positions only; changes compare share counts with Q4 2025.

Institution overview
Positions
85
−2 vs. Q4 2025
Portfolio value
$168.0M
−$47.9M (−22.2%) vs. Q4 2025
Filed
May 14, 2026
SEC
Holdings of Knott David M Jr in Q1 2026
SecurityClassSharesValue% of portfolioShare changeActionHistory
GOOGAlphabet Inc.Stock91,420$26.2M15.6%00.0%UnchangedHistory
APOApollo Global Management, Inc.COM225,000$25.1M14.9%00.0%UnchangedHistory
SNDXSyndax Pharmaceuticals IncCOM422,000$9.86M5.9%+7,000+1.7%AddedHistory
BBIOBridgeBio Pharma, Inc.COM90,000$6.68M4.0%+5,000+5.9%AddedHistory
PTGXProtagonist Therapeutics, IncCOM63,000$6.64M4.0%−10,000−13.7%ReducedHistory
XERSXeris Biopharma Holdings, Inc.COM1,060,000$6.15M3.7%+90,000+9.3%AddedHistory
JPMJPMorgan Chase & CoStock19,477$5.73M3.4%00.0%UnchangedHistory
IOVAIovance Biotherapeutics, Inc.COM1,600,000$5.62M3.3%+1,600,000NewHistory
LPLALPL Financial Holdings Inc.Common16,500$4.96M3.0%+16,500NewHistory
Janus Detroit STR Tr47103U845HENDRSON AAA CL93,528$4.71M2.8%00.0%Unchanged–
ALKSAlkermes plc.SHS120,000$4.24M2.5%+25,000+26.3%AddedHistory
TVTXTravere Therapeutics, Inc.COM140,633$4.18M2.5%−45,367−24.4%ReducedHistory
COGTCogent Biosciences, Inc.COM104,000$4.00M2.4%+2,000+2.0%AddedHistory
VRDNViridian Therapeutics, Inc.COM181,000$3.54M2.1%+36,000+24.8%AddedHistory
AGIOAgios Pharmaceuticals, Inc.COM93,058$3.15M1.9%+75,058+417.0%AddedHistory
RLMDRelmada Therapeutics, Inc.COM439,300$3.06M1.8%+439,300NewHistory
TGTXTG Therapeutics, Inc.COM90,001$2.99M1.8%+45,001+100.0%AddedHistory
CPRXCatalyst Pharmaceuticals, Inc.COM120,000$2.97M1.8%−69,000−36.5%ReducedHistory
ACLXArcellx, Inc.COMMON STOCK19,433$2.23M1.3%−6,267−24.4%ReducedHistory
State Street SPDR S&P Biotech ETF78464A870ETF15,000$1.92M1.1%+2,000+15.4%Added–
ABAlliancebernstein Holding L.P.UNIT LTD PARTN48,000$1.80M1.1%00.0%UnchangedHistory
RCUSArcus Biosciences, Inc.COM81,241$1.75M1.0%−40,000−33.0%ReducedHistory
DCGODocGo Inc.COM2,670,850$1.68M1.0%00.0%UnchangedHistory
HELPCybin Inc.COM NEW350,000$1.68M1.0%+64,818+22.7%AddedHistory
CYTKCytokinetics IncCOM NEW23,644$1.56M0.9%−10,356−30.5%ReducedHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS39,000$1.55M0.9%+35,000+875.0%AddedHistory
ATRCAtriCure, Inc.COM51,400$1.47M0.9%00.0%UnchangedHistory
ARDXArdelyx, Inc.COM207,000$1.24M0.7%+207,000NewHistory
Series Portfolios Tr81752T528ELDRIDGE BBB B47,807$1.23M0.7%00.0%Unchanged–
JNJJohnson & JohnsonStock4,922$1.20M0.7%−2,000−28.9%ReducedHistory
RZLTRezolute, Inc.COM NEW370,000$1.13M0.7%+30,000+8.8%AddedHistory
OBIOOrchestra BioMed Holdings, Inc.COM253,651$1.08M0.6%+3,651+1.5%AddedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM2,000$1.05M0.6%00.0%UnchangedHistory
VERAVera Therapeutics, Inc.CL A26,000$1.05M0.6%00.0%UnchangedHistory
CNTBConnect Biopharma Holdings LtdSHS387,835$1.02M0.6%+187,835+93.9%AddedHistory
iShares Tr464287556ISHARES BIOTECH5,500$928.7K0.6%00.0%Unchanged–
PFEPfizer IncStock32,337$908.0K0.5%00.0%UnchangedHistory
BMYBristol Myers Squibb CoStock13,622$826.2K0.5%−8,378−38.1%ReducedHistory
CNQCanadian Natural Resources LtdCOM16,800$818.7K0.5%00.0%UnchangedHistory
BIIBBiogen Inc.COM4,000$733.3K0.4%−2,000−33.3%ReducedHistory
RAREUltragenyx Pharmaceutical Inc.COM33,069$692.8K0.4%+13,063+65.3%AddedHistory
AAPLApple Inc.Stock2,494$633.0K0.4%00.0%UnchangedHistory
MSFTMicrosoft CorpStock1,600$592.3K0.4%00.0%UnchangedHistory
VSTMVerastem, Inc.COM NEW104,000$551.2K0.3%+104,000NewHistory
ADMAAdma Biologics, Inc.COM60,200$542.4K0.3%00.0%UnchangedHistory
IBMInternational Business Machines CorpStock2,142$519.3K0.3%00.0%UnchangedHistory
Biohaven Pharmaceutical Holding Co Ltd.G111OE107Common60,720$513.7K0.3%+60,720New–
PTHSPelthos Therapeutics Inc.COM SHS21,073$442.7K0.3%+1,792+9.3%AddedHistory
KURAKura Oncology, Inc.COM52,767$429.0K0.3%+13,558+34.6%AddedHistory
EOLSEvolus, Inc.COM99,338$408.3K0.2%00.0%UnchangedHistory
CGEMCullinan Therapeutics, Inc.COM24,200$343.9K0.2%+24,200NewHistory
SLDBSolid Biosciences Inc.COM NEW47,143$339.4K0.2%−115,297−71.0%ReducedHistory
LENZLENZ Therapeutics, Inc.COM33,732$308.6K0.2%−20,000−37.2%ReducedHistory
WVEWave Life Sciences, Inc.SHS40,000$290.0K0.2%−50,000−55.6%ReducedHistory
RAINRain Enhancement Technologies Holdco, Inc.CL A101,686$258.3K0.2%+101,686NewHistory
KMBKimberly Clark CorpStock2,400$231.5K0.1%00.0%UnchangedHistory
NVDANVIDIA CorpStock1,280$223.3K0.1%00.0%UnchangedHistory
RHPRyman Hospitality Properties, Inc.COM2,400$221.4K0.1%00.0%UnchangedHistory
AVGOBroadcom Inc.Stock710$219.9K0.1%00.0%UnchangedHistory
MDLZMondelez International, Inc.Stock3,000$172.9K0.1%00.0%UnchangedHistory
DDDuPont de Nemours, Inc.COM3,767$172.5K0.1%00.0%UnchangedHistory
JSPRJasper Therapeutics, Inc.COM NEW160,789$140.9K0.1%−20,600−11.4%ReducedHistory
IVVDInvivyd, Inc.COM100,000$130.0K0.1%00.0%UnchangedHistory
CTVACorteva, Inc.Stock1,206$101.0K0.1%00.0%UnchangedHistory
MREOMereo BioPharma Group plcSPON ADS300,337$99.1K0.1%00.0%UnchangedHistory
EBCEastern Bankshares, Inc.COM5,000$97.8K0.1%00.0%UnchangedHistory
PWRQuanta Services, Inc.COM176$96.6K0.1%00.0%UnchangedHistory
iShares Russell Mid-Cap Growth ETF464287481ETF695$89.0K0.1%00.0%Unchanged–
GOOGLAlphabet Inc.Stock300$86.3K0.1%00.0%UnchangedHistory
LEGHLegacy Housing CorpCOM4,000$81.7K<0.1%00.0%UnchangedHistory
AMZNAmazon Com IncStock300$62.5K<0.1%00.0%UnchangedHistory
URIUnited Rentals, Inc.COM78$56.8K<0.1%00.0%UnchangedHistory
DOWDow Inc.Stock1,206$50.2K<0.1%00.0%UnchangedHistory
OXYOccidental Petroleum CorpStock663$34.7K<0.1%00.0%UnchangedHistory
DHRDanaher CorpStock180$34.1K<0.1%00.0%UnchangedHistory
BRSLBrightstar Lottery PLCSHS USD2,500$31.9K<0.1%+2,500NewHistory
FSKFS KKR Capital CorpCOM2,875$29.3K<0.1%+2,875NewHistory
BXBlackstone Inc.COM210$24.1K<0.1%00.0%UnchangedHistory
TMOThermo Fisher Scientific Inc.Stock45$22.1K<0.1%00.0%UnchangedHistory
UNHUnitedHealth Group IncStock57$15.4K<0.1%00.0%UnchangedHistory
CRMSalesforce, Inc.Stock77$14.4K<0.1%00.0%UnchangedHistory
STWDStarwood Property Trust, Inc.COM400$6.89K<0.1%00.0%UnchangedHistory
KDKyndryl Holdings, Inc.Stock428$5.62K<0.1%00.0%UnchangedHistory
GEHCGE HealthCare Technologies Inc.Stock50$3.56K<0.1%00.0%UnchangedHistory
WABWestinghouse Air Brake Technologies CorpStock6$1.50K<0.1%00.0%UnchangedHistory

Sold out since Q4 2025 (12)

Positions held at the end of Q4 2025 that are gone from this filing.

Positions of Knott David M Jr sold out since Q4 2025
SecurityClassShares in Q4 2025Value in Q4 2025% of portfolio in Q4 2025History
CLMTCalumet, Inc.COM2,214,969$44.0M20.4%History
TECXTectonic Therapeutic, Inc.COM74,000$1.54M0.7%History
BHVNBiohaven Ltd.COM110,720$1.25M0.6%History
NKTRNektar TherapeuticsCOM NEW15,500$655.3K0.3%History
SRRKScholar Rock Holding CorpCOM13,913$612.9K0.3%History
XENEXenon Pharmaceuticals Inc.COM10,962$491.3K0.2%History
MRSNMersana Therapeutics, Inc.COMMON STOCK111,686$437.8K0.2%History
FATEFate Therapeutics IncCOM365,000$358.6K0.2%History
DAWNDay One Biopharmaceuticals, Inc.Stock25,884$241.2K0.1%History
QUREuniQure N.V.SHS4,000$95.7K<0.1%History
FSKFS KKR Capital CorpCOM2,875$42.6K<0.1%History
Intl Game Tech PLC Com459902102Equity2,500$38.7K<0.1%–