Skip to main content

Knott David M Jr

SEC CIK
0001892770
Latest filing
Aug 12, 2026

Holdings in Q3 2025

Holdings as of Sep 30, 2025, filed Nov 12, 2025. Long positions only; changes compare share counts with Q2 2025.

Institution overview
Positions
87
+2 vs. Q2 2025
Portfolio value
$238.7M
+$18.1M (+8.2%) vs. Q2 2025
Filed
Nov 12, 2025
SEC
Holdings of Knott David M Jr in Q3 2025
SecurityClassSharesValue% of portfolioShare changeActionHistory
CLMTCalumet, Inc.COM2,825,231$51.6M21.6%−450,000−13.7%ReducedHistory
APOApollo Global Management, Inc.COM225,000$30.0M12.6%00.0%UnchangedHistory
GOOGAlphabet Inc.Stock112,220$27.3M11.4%00.0%UnchangedHistory
Janus Detroit STR Tr47103U845HENDRSON AAA CL437,754$22.2M9.3%−57,500−11.6%Reduced–
XERSXeris Biopharma Holdings, Inc.COM1,015,000$8.26M3.5%−45,000−4.2%ReducedHistory
SNDXSyndax Pharmaceuticals IncCOM428,000$6.58M2.8%+75,222+21.3%AddedHistory
JPMJPMorgan Chase & CoStock20,374$6.43M2.7%−611−2.9%ReducedHistory
TVTXTravere Therapeutics, Inc.COM260,000$6.21M2.6%00.0%UnchangedHistory
AVDLAvadel Pharmaceuticals PLCStock363,000$5.54M2.3%−63,000−14.8%ReducedHistory
PTGXProtagonist Therapeutics, IncCOM83,000$5.51M2.3%+3,000+3.8%AddedHistory
BBIOBridgeBio Pharma, Inc.COM85,000$4.41M1.8%+5,000+6.3%AddedHistory
DCGODocGo Inc.COM3,070,850$4.18M1.7%00.0%UnchangedHistory
VRNAVerona Pharma plcSPONSORED ADS38,355$4.09M1.7%−16,645−30.3%ReducedHistory
LENZLENZ Therapeutics, Inc.COM82,000$3.82M1.6%00.0%UnchangedHistory
CPRXCatalyst Pharmaceuticals, Inc.COM189,000$3.72M1.6%+13,000+7.4%AddedHistory
RZLTRezolute, Inc.COM NEW275,000$2.58M1.1%+275,000NewHistory
VRDNViridian Therapeutics, Inc.COM116,574$2.52M1.1%+25,091+27.4%AddedHistory
CSXCSX CorpStock70,000$2.48M1.0%00.0%UnchangedHistory
LQDALiquidia CorpCOM NEW107,783$2.45M1.0%+17,783+19.8%AddedHistory
ACLXArcellx, Inc.COMMON STOCK25,700$2.11M0.9%00.0%UnchangedHistory
PFEPfizer IncStock74,537$1.90M0.8%00.0%UnchangedHistory
ABAlliancebernstein Holding L.P.UNIT LTD PARTN48,000$1.83M0.8%00.0%UnchangedHistory
ATRCAtriCure, Inc.COM48,000$1.69M0.7%+1,557+3.4%AddedHistory
CYTKCytokinetics IncCOM NEW30,000$1.65M0.7%+30,000NewHistory
RAREUltragenyx Pharmaceutical Inc.COM52,000$1.56M0.7%00.0%UnchangedHistory
PRAXPraxis Precision Medicines, Inc.COM NEW28,000$1.48M0.6%+28,000NewHistory
RCUSArcus Biosciences, Inc.COM95,200$1.29M0.5%+25,200+36.0%AddedHistory
JNJJohnson & JohnsonStock6,922$1.28M0.5%00.0%UnchangedHistory
Series Portfolios Tr81752T528ELDRIDGE BBB B47,807$1.28M0.5%00.0%Unchanged–
BMYBristol Myers Squibb CoStock27,000$1.22M0.5%00.0%UnchangedHistory
ABBVAbbVie Inc.Stock5,037$1.17M0.5%00.0%UnchangedHistory
TECXTectonic Therapeutic, Inc.COM74,000$1.16M0.5%00.0%UnchangedHistory
RHPRyman Hospitality Properties, Inc.COM12,000$1.08M0.5%00.0%UnchangedHistory
SLDBSolid Biosciences Inc.COM NEW162,440$1.00M0.4%00.0%UnchangedHistory
DAWNDay One Biopharmaceuticals, Inc.Stock130,500$920.0K0.4%+96,786+287.1%AddedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM2,000$917.3K0.4%00.0%UnchangedHistory
MSFTMicrosoft CorpStock1,600$828.7K0.3%00.0%UnchangedHistory
HELPCybin Inc.COM NEW140,242$826.0K0.3%+73,362+109.7%AddedHistory
VERAVera Therapeutics, Inc.CL A26,000$755.6K0.3%+6,000+30.0%AddedHistory
CTVACorteva, Inc.Stock11,051$747.4K0.3%00.0%UnchangedHistory
KMBKimberly Clark CorpStock6,000$746.0K0.3%00.0%UnchangedHistory
DDDuPont de Nemours, Inc.COM9,418$733.7K0.3%00.0%UnchangedHistory
WVEWave Life Sciences, Inc.SHS90,000$658.8K0.3%+50,000+125.0%AddedHistory
iShares Tr464287556ISHARES BIOTECH4,500$649.7K0.3%+2,500+125.0%Added–
AAPLApple Inc.Stock2,494$635.0K0.3%00.0%UnchangedHistory
MREOMereo BioPharma Group plcSPON ADS300,337$618.7K0.3%−19,000−5.9%ReducedHistory
IBMInternational Business Machines CorpStock2,142$604.4K0.3%00.0%UnchangedHistory
KURAKura Oncology, Inc.COM67,302$595.6K0.2%+67,302NewHistory
ALKSAlkermes plc.SHS19,300$579.0K0.2%−29,700−60.6%ReducedHistory
CNQCanadian Natural Resources LtdCOM16,800$536.9K0.2%00.0%UnchangedHistory
State Street SPDR S&P Biotech ETF78464A870ETF5,000$501.0K0.2%+2,000+66.7%Added–
MDLZMondelez International, Inc.Stock8,000$499.7K0.2%+8,000NewHistory
OBIOOrchestra BioMed Holdings, Inc.COM195,000$483.6K0.2%+95,000+95.0%AddedHistory
FATEFate Therapeutics IncCOM365,000$459.9K0.2%+365,000NewHistory
XENEXenon Pharmaceuticals Inc.COM10,962$440.1K0.2%00.0%UnchangedHistory
JSPRJasper Therapeutics, Inc.COM NEW171,389$407.9K0.2%+171,389NewHistory
SRRKScholar Rock Holding CorpCOM9,000$335.2K0.1%+9,000NewHistory
BIIBBiogen Inc.COM2,000$280.2K0.1%+2,000NewHistory
BCRXBiocryst Pharmaceuticals IncCOM32,570$247.2K0.1%−300,055−90.2%ReducedHistory
NVDANVIDIA CorpStock1,280$238.8K0.1%00.0%UnchangedHistory
AVGOBroadcom Inc.Stock710$234.2K0.1%00.0%UnchangedHistory
LLYEli Lilly & CoStock300$228.9K0.1%00.0%UnchangedHistory
PTHSPelthos Therapeutics Inc.COM SHS6,112$171.1K0.1%+6,112NewHistory
QUREuniQure N.V.SHS2,000$116.7K<0.1%+2,000NewHistory
LEGHLegacy Housing CorpCOM4,000$110.0K<0.1%00.0%UnchangedHistory
IVVDInvivyd, Inc.COM100,000$110.0K<0.1%+100,000NewHistory
iShares Russell Midcap ETF464287499ETF695$99.0K<0.1%+695New–
EBCEastern Bankshares, Inc.COM5,000$90.8K<0.1%00.0%UnchangedHistory
URIUnited Rentals, Inc.COM78$74.5K<0.1%00.0%UnchangedHistory
PWRQuanta Services, Inc.COM176$72.9K<0.1%00.0%UnchangedHistory
GOOGLAlphabet Inc.Stock300$72.9K<0.1%00.0%UnchangedHistory
TTETotalEnergies SESPONSORED ADS1,200$71.6K<0.1%00.0%UnchangedHistory
AMZNAmazon Com IncStock300$65.9K<0.1%00.0%UnchangedHistory
BRSLBrightstar Lottery PLCSHS USD2,500$43.1K<0.1%00.0%UnchangedHistory
FSKFS KKR Capital CorpCOM2,875$42.9K<0.1%+2,875NewHistory
BXBlackstone Inc.COM210$35.9K<0.1%00.0%UnchangedHistory
DHRDanaher CorpStock180$35.7K<0.1%00.0%UnchangedHistory
DOWDow Inc.Stock1,206$27.7K<0.1%00.0%UnchangedHistory
OXYOccidental Petroleum CorpStock663$26.4K<0.1%00.0%UnchangedHistory
TMOThermo Fisher Scientific Inc.Stock45$21.8K<0.1%00.0%UnchangedHistory
Arc Resources Ltd00208D408COM1,110$20.2K<0.1%00.0%Unchanged–
UNHUnitedHealth Group IncStock57$19.7K<0.1%00.0%UnchangedHistory
CRMSalesforce, Inc.Stock77$18.2K<0.1%00.0%UnchangedHistory
KDKyndryl Holdings, Inc.Stock428$12.9K<0.1%00.0%UnchangedHistory
STWDStarwood Property Trust, Inc.COM400$7.75K<0.1%00.0%UnchangedHistory
GEHCGE HealthCare Technologies Inc.Stock50$3.75K<0.1%00.0%UnchangedHistory
WABWestinghouse Air Brake Technologies CorpStock6$1.20K<0.1%00.0%UnchangedHistory

Options (1)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Knott David M Jr in Q3 2025
SecurityClassPutsCalls
DARDarling Ingredients Inc.COM–$9.26M

Sold out since Q2 2025 (12)

Positions held at the end of Q2 2025 that are gone from this filing.

Positions of Knott David M Jr sold out since Q2 2025
SecurityClassShares in Q2 2025Value in Q2 2025% of portfolio in Q2 2025History
INZYInozyme Pharma, Inc.COM666,204$2.66M1.2%History
ESGREnstar Group LTDSHS7,500$2.52M1.1%History
MYGNMyriad Genetics IncCOM180,000$955.8K0.4%History
COLLCollegium Pharmaceutical, IncCOM23,511$695.2K0.3%History
AXSMAxsome Therapeutics, Inc.COM6,000$626.3K0.3%History
AUTLAutolus Therapeutics plcSPON ADS270,000$615.6K0.3%History
Kraft Foods Inc50075N104COM9,000$607.0K0.3%–
ATYRaTYR PHARMA INCCOM NEW50,367$255.4K0.1%History
KOCoca Cola CoStock2,000$141.5K0.1%History
iShares Russell Mid-Cap Growth ETF464287481ETF695$96.4K<0.1%–
FSKFS KKR Capital CorpCOM2,875$59.7K<0.1%History
FSBWFS Bancorp, Inc.COM1,460$57.5K<0.1%History