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Logos Global Management LP

SEC CIK
0001792126
Latest filing
Aug 14, 2026

Holdings in Q3 2025

Holdings as of Sep 30, 2025, filed Nov 14, 2025. Long positions only; changes compare share counts with Q2 2025.

Institution overview
Positions
53
+8 vs. Q2 2025
Portfolio value
$1.01B
+$263.7M (+35.2%) vs. Q2 2025
Filed
Nov 14, 2025
SEC
Holdings of Logos Global Management LP in Q3 2025
SecurityClassSharesValue% of portfolioShare changeActionHistory
RVMDRevolution Medicines, Inc.COM1,750,000$81.7M8.1%+50,000+2.9%AddedHistory
IDYAIDEAYA Biosciences, Inc.COM2,250,000$61.2M6.0%−1,095,000−32.7%ReducedHistory
AKROAkero Therapeutics, Inc.COM1,200,000$57.0M5.6%00.0%UnchangedHistory
ARVNArvinas, Inc.COM5,575,000$47.5M4.7%+2,275,000+68.9%AddedHistory
OCULOcular Therapeutix, IncCOM3,250,000$38.0M3.8%+1,050,000+47.7%AddedHistory
CDTXCidara Therapeutics, Inc.COM NEW375,000$35.9M3.5%+185,000+97.4%AddedHistory
VSTMVerastem, Inc.COM NEW4,050,000$35.8M3.5%+3,050,000+305.0%AddedHistory
ABVXAbivax S.A.SPONSORED ADS415,000$35.2M3.5%+415,000NewHistory
ERASErasca, Inc.COM15,150,000$33.0M3.3%+150,000+1.0%AddedHistory
MAZEMaze Therapeutics, Inc.COM1,227,300$31.8M3.1%+615,386+100.6%AddedHistory
OLMAOlema Pharmaceuticals, Inc.COM3,208,875$31.4M3.1%00.0%UnchangedHistory
IMCRImmunocore Holdings plcADS850,000$30.9M3.1%+275,000+47.8%AddedHistory
DYNDyne Therapeutics, Inc.COM2,400,000$30.4M3.0%+500,000+26.3%AddedHistory
IRONDisc Medicine, Inc.COM450,000$29.7M2.9%−250,000−35.7%ReducedHistory
DSGNDesign Therapeutics, Inc.COM3,655,000$27.5M2.7%−562,627−13.3%ReducedHistory
JAZZJazz Pharmaceuticals plcSHS USD200,000$26.4M2.6%−250,000−55.6%ReducedHistory
Avidity Biosciences, Inc.05370A108COM600,000$26.1M2.6%−350,000−36.8%Reduced–
GPCRStructure Therapeutics Inc.SPONSORED ADS850,000$23.8M2.4%00.0%UnchangedHistory
JANXJanux Therapeutics, Inc.COM935,000$22.9M2.3%−65,000−6.5%ReducedHistory
PCVXVaxcyte, Inc.COM625,000$22.5M2.2%+625,000NewHistory
RYTMRhythm Pharmaceuticals, Inc.COM200,000$20.2M2.0%+70,000+53.8%AddedHistory
TRVITrevi Therapeutics, Inc.COM2,200,000$20.1M2.0%+1,350,000+158.8%AddedHistory
PTGXProtagonist Therapeutics, IncCOM300,000$19.9M2.0%+300,000NewHistory
AMLXAmylyx Pharmaceuticals, Inc.COM1,450,000$19.7M1.9%+1,450,000NewHistory
LBRXLB Pharmaceuticals IncCOM SHS1,130,000$17.8M1.8%+1,130,000NewHistory
QUREuniQure N.V.SHS300,000$17.5M1.7%+300,000NewHistory
KYMRKymera Therapeutics, Inc.COM250,000$14.2M1.4%+250,000NewHistory
BIIBBiogen Inc.COM100,000$14.0M1.4%−100,000−50.0%ReducedHistory
ACLXArcellx, Inc.COMMON STOCK165,000$13.5M1.3%+165,000NewHistory
KROSKeros Therapeutics, Inc.COM850,000$13.4M1.3%−1,150,000−57.5%ReducedHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS525,000$12.7M1.3%+525,000NewHistory
TNGXTango Therapeutics, Inc.COM950,000$7.98M0.8%+950,000NewHistory
DNTHDianthus Therapeutics, Inc.COM200,000$7.87M0.8%+200,000NewHistory
COGTCogent Biosciences, Inc.COM500,000$7.18M0.7%+500,000NewHistory
CMPXCompass Therapeutics, Inc.COM2,050,000$7.17M0.7%+2,050,000NewHistory
CBIOCrescent Biopharma, Inc.COM600,000$7.13M0.7%+46,314+8.4%AddedHistory
ELVNEnliven Therapeutics, Inc.COM340,000$6.96M0.7%−10,000−2.9%ReducedHistory
IMRXImmuneering CorpCLASS A COM950,000$6.65M0.7%+950,000NewHistory
PRAXPraxis Precision Medicines, Inc.COM NEW125,000$6.63M0.7%−100,000−44.4%ReducedHistory
SRRKScholar Rock Holding CorpCOM175,000$6.52M0.6%+175,000NewHistory
JBIOJade Biosciences, Inc.COM NEW625,000$5.39M0.5%00.0%UnchangedHistory
EPRXEupraxia Pharmaceuticals Inc.COM900,000$5.31M0.5%+900,000NewHistory
IMVTImmunovant, Inc.COM275,000$4.43M0.4%00.0%UnchangedHistory
PHVSPharvaris N.V.COM150,000$3.74M0.4%+150,000NewHistory
ATXSAstria Therapeutics, Inc.COM500,000$3.64M0.4%−200,000−28.6%ReducedHistory
PEPGPepGen Inc.COM750,000$3.46M0.3%+750,000NewHistory
ACRSAclaris Therapeutics, Inc.COM1,500,000$2.85M0.3%−350,000−18.9%ReducedHistory
UNCYUnicycive Therapeutics, Inc.COM NEW473,563$2.06M0.2%+10.0%AddedHistory
ESPREsperion Therapeutics, Inc.COM750,000$1.99M0.2%+750,000NewHistory
SEPNSepterna, Inc.COM83,548$1.57M0.2%−25,654−23.5%ReducedHistory
MREOMereo BioPharma Group plcSPON ADS500,000$1.03M0.1%+500,000NewHistory
GUTSFractyl Health, Inc.COM500,000$795.0K0.1%+500,000NewHistory
Nuvation Bio Inc.67080N119*W EXP 07/07/20266,666$13.5K<0.1%00.0%Unchanged–

Options (6)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Logos Global Management LP in Q3 2025
SecurityClassPutsCalls
RVMDRevolution Medicines, Inc.COM–$46.7M
APLSApellis Pharmaceuticals, Inc.COM–$22.6M
IDYAIDEAYA Biosciences, Inc.COM–$12.2M
JANXJanux Therapeutics, Inc.COM–$12.2M
LRMRLarimar Therapeutics, Inc.COM–$8.07M
ALECAlector, Inc.COM–$1.48M

Sold out since Q2 2025 (13)

Positions held at the end of Q2 2025 that are gone from this filing.

Positions of Logos Global Management LP sold out since Q2 2025
SecurityClassShares in Q2 2025Value in Q2 2025% of portfolio in Q2 2025History
UTHRUnited Therapeutics CorpCOM85,000$24.4M3.3%History
NBIXNeurocrine Biosciences IncStock150,000$18.9M2.5%History
MDGLMadrigal Pharmaceuticals, Inc.COM50,000$15.1M2.0%History
KRYSKrystal Biotech, Inc.COM100,000$13.7M1.8%History
CLDXCelldex Therapeutics, Inc.COM NEW600,000$12.2M1.6%History
BHVNBiohaven Ltd.COM700,000$9.88M1.3%History
XNCRXencor IncCOM1,250,000$9.82M1.3%History
MLTXMoonLake ImmunotherapeuticsCLASS A ORD200,000$9.44M1.3%History
LEGNLegend Biotech CorpSPONSORED ADS250,000$8.87M1.2%History
ANNXAnnexon, Inc.COM2,410,000$5.78M0.8%History
MTSRMetsera, Inc.COM200,000$5.69M0.8%History
BCAXBicara Therapeutics Inc.COM400,000$3.72M0.5%History
RAPPRapport Therapeutics, Inc.COM208,910$2.38M0.3%History