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Logos Global Management LP

SEC CIK
0001792126
Latest filing
Aug 14, 2026

Holdings in Q2 2025

Holdings as of Jun 30, 2025, filed Aug 14, 2025. Long positions only; changes compare share counts with Q1 2025.

Institution overview
Positions
45
+6 vs. Q1 2025
Portfolio value
$748.6M
+$186.1M (+33.1%) vs. Q1 2025
Filed
Aug 14, 2025
SEC
Holdings of Logos Global Management LP in Q2 2025
SecurityClassSharesValue% of portfolioShare changeActionHistory
IDYAIDEAYA Biosciences, Inc.COM3,345,000$70.3M9.4%−155,000−4.4%ReducedHistory
AKROAkero Therapeutics, Inc.COM1,200,000$64.0M8.6%00.0%UnchangedHistory
RVMDRevolution Medicines, Inc.COM1,700,000$62.5M8.4%+100,000+6.3%AddedHistory
JAZZJazz Pharmaceuticals plcSHS USD450,000$47.8M6.4%+450,000NewHistory
IRONDisc Medicine, Inc.COM700,000$37.1M5.0%+305,658+77.5%AddedHistory
Avidity Biosciences, Inc.05370A108COM950,000$27.0M3.6%+600,000+171.4%Added–
KROSKeros Therapeutics, Inc.COM2,000,000$26.7M3.6%00.0%UnchangedHistory
BIIBBiogen Inc.COM200,000$25.1M3.4%+200,000NewHistory
UTHRUnited Therapeutics CorpCOM85,000$24.4M3.3%+85,000NewHistory
ARVNArvinas, Inc.COM3,300,000$24.3M3.2%+3,300,000NewHistory
JANXJanux Therapeutics, Inc.COM1,000,000$23.1M3.1%−650,000−39.4%ReducedHistory
OCULOcular Therapeutix, IncCOM2,200,000$20.4M2.7%−100,000−4.3%ReducedHistory
ERASErasca, Inc.COM15,000,000$19.1M2.5%+2,000,000+15.4%AddedHistory
NBIXNeurocrine Biosciences IncStock150,000$18.9M2.5%+150,000NewHistory
DYNDyne Therapeutics, Inc.COM1,900,000$18.1M2.4%+1,400,000+280.0%AddedHistory
IMCRImmunocore Holdings plcADS575,000$18.0M2.4%+575,000NewHistory
GPCRStructure Therapeutics Inc.SPONSORED ADS850,000$17.6M2.4%+425,000+100.0%AddedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM50,000$15.1M2.0%+50,000NewHistory
DSGNDesign Therapeutics, Inc.COM4,217,627$14.2M1.9%00.0%UnchangedHistory
KRYSKrystal Biotech, Inc.COM100,000$13.7M1.8%+100,000NewHistory
OLMAOlema Pharmaceuticals, Inc.COM3,208,875$13.7M1.8%00.0%UnchangedHistory
CLDXCelldex Therapeutics, Inc.COM NEW600,000$12.2M1.6%+600,000NewHistory
BHVNBiohaven Ltd.COM700,000$9.88M1.3%+700,000NewHistory
XNCRXencor IncCOM1,250,000$9.82M1.3%+1,250,000NewHistory
PRAXPraxis Precision Medicines, Inc.COM NEW225,000$9.46M1.3%+225,000NewHistory
MLTXMoonLake ImmunotherapeuticsCLASS A ORD200,000$9.44M1.3%−150,000−42.9%ReducedHistory
CDTXCidara Therapeutics, Inc.COM NEW190,000$9.25M1.2%+190,000NewHistory
CBIOCrescent Biopharma, Inc.COM553,686$8.94M1.2%+553,686NewHistory
LEGNLegend Biotech CorpSPONSORED ADS250,000$8.87M1.2%+250,000NewHistory
RYTMRhythm Pharmaceuticals, Inc.COM130,000$8.21M1.1%+130,000NewHistory
MAZEMaze Therapeutics, Inc.COM611,914$7.51M1.0%−325,000−34.7%ReducedHistory
ELVNEnliven Therapeutics, Inc.COM350,000$7.02M0.9%+110,000+45.8%AddedHistory
JBIOJade Biosciences, Inc.COM NEW625,000$6.24M0.8%+625,000NewHistory
ANNXAnnexon, Inc.COM2,410,000$5.78M0.8%−1,590,000−39.8%ReducedHistory
MTSRMetsera, Inc.COM200,000$5.69M0.8%+200,000NewHistory
TRVITrevi Therapeutics, Inc.COM850,000$4.65M0.6%+425,285+100.1%AddedHistory
IMVTImmunovant, Inc.COM275,000$4.40M0.6%00.0%UnchangedHistory
VSTMVerastem, Inc.COM NEW1,000,000$4.15M0.6%+1,000,000NewHistory
ATXSAstria Therapeutics, Inc.COM700,000$3.75M0.5%+200,000+40.0%AddedHistory
BCAXBicara Therapeutics Inc.COM400,000$3.72M0.5%+400,000NewHistory
ACRSAclaris Therapeutics, Inc.COM1,850,000$2.63M0.4%−372,222−16.7%ReducedHistory
RAPPRapport Therapeutics, Inc.COM208,910$2.38M0.3%00.0%UnchangedHistory
UNCYUnicycive Therapeutics, Inc.COM NEW473,562$2.26M0.3%−34,331−6.8%ReducedConverted for a 1-for-10 splitHistory
SEPNSepterna, Inc.COM109,202$1.15M0.2%−25,000−18.6%ReducedHistory
Nuvation Bio Inc.67080N119*W EXP 07/07/20266,666$18.0K<0.1%00.0%Unchanged–

Options (6)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Logos Global Management LP in Q2 2025
SecurityClassPutsCalls
State Street SPDR S&P Biotech ETF78464A870ETF–$82.9M
TEVATeva Pharmaceutical Industries LtdSPONSORED ADS–$25.1M
APLSApellis Pharmaceuticals, Inc.COM–$17.3M
JANXJanux Therapeutics, Inc.COM–$11.6M
ARVNArvinas, Inc.COM–$11.0M
LRMRLarimar Therapeutics, Inc.COM–$7.22M

Sold out since Q1 2025 (14)

Positions held at the end of Q1 2025 that are gone from this filing.

Positions of Logos Global Management LP sold out since Q1 2025
SecurityClassShares in Q1 2025Value in Q1 2025% of portfolio in Q1 2025History
NUVLNuvalent, Inc.COM500,000$35.5M6.3%History
TEVATeva Pharmaceutical Industries LtdSPONSORED ADS1,700,000$26.1M4.6%History
XENEXenon Pharmaceuticals Inc.COM650,000$21.8M3.9%History
BNTXBioNTech SESPONSORED ADS200,000$18.2M3.2%History
ETNB89bio, Inc.COM2,500,000$18.2M3.2%History
SLNOSoleno Therapeutics IncCOM250,000$17.9M3.2%History
GERNGeron CorpCOM8,000,000$12.7M2.3%History
CRNXCrinetics Pharmaceuticals, Inc.COM350,000$11.7M2.1%History
CMPSCOMPASS Pathways plcSPONSORED ADS2,000,000$5.72M1.0%History
JBIOJade Biosciences, Inc.COM1,400,000$3.51M0.6%History
CBIOCrescent Biopharma, Inc.COM5,400,000$1.13M0.2%History
ALLKAllakos Inc.COM2,900,000$660.0K0.1%History
ARTVArtiva Biotherapeutics, Inc.COM145,089$435.3K0.1%History
SLDBSolid Biosciences Inc.COM NEW100,000$370.0K0.1%History