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Logos Global Management LP

SEC CIK
0001792126
Latest filing
Aug 14, 2026

Holdings in Q4 2025

Holdings as of Dec 31, 2025, filed Feb 17, 2026. Long positions only; changes compare share counts with Q3 2025.

Institution overview
Positions
64
+11 vs. Q3 2025
Portfolio value
$1.50B
+$488.3M (+48.2%) vs. Q3 2025
Filed
Feb 17, 2026
SEC
Holdings of Logos Global Management LP in Q4 2025
SecurityClassSharesValue% of portfolioShare changeActionHistory
RVMDRevolution Medicines, Inc.COM2,000,000$159.3M10.6%+250,000+14.3%AddedHistory
PRAXPraxis Precision Medicines, Inc.COM NEW375,000$110.5M7.4%+250,000+200.0%AddedHistory
IDYAIDEAYA Biosciences, Inc.COM3,125,000$108.0M7.2%+875,000+38.9%AddedHistory
OLMAOlema Pharmaceuticals, Inc.COM3,208,875$80.2M5.3%00.0%UnchangedHistory
CDTXCidara Therapeutics, Inc.COM NEW310,000$68.5M4.6%−65,000−17.3%ReducedHistory
ABVXAbivax S.A.SPONSORED ADS400,000$53.9M3.6%−15,000−3.6%ReducedHistory
ERASErasca, Inc.COM13,000,000$48.4M3.2%−2,150,000−14.2%ReducedHistory
OCULOcular Therapeutix, IncCOM3,500,000$42.5M2.8%+250,000+7.7%AddedHistory
GPCRStructure Therapeutics Inc.SPONSORED ADS600,000$41.7M2.8%−250,000−29.4%ReducedHistory
IRONDisc Medicine, Inc.COM510,000$40.5M2.7%+60,000+13.3%AddedHistory
MAZEMaze Therapeutics, Inc.COM950,000$39.4M2.6%−277,300−22.6%ReducedHistory
TNGXTango Therapeutics, Inc.COM4,200,000$37.2M2.5%+3,250,000+342.1%AddedHistory
Avidity Biosciences, Inc.05370A108COM500,000$36.1M2.4%−100,000−16.7%Reduced–
BIIBBiogen Inc.COM200,000$35.2M2.3%+100,000+100.0%AddedHistory
IMVTImmunovant, Inc.COM1,375,000$35.0M2.3%+1,100,000+400.0%AddedHistory
JAZZJazz Pharmaceuticals plcSHS USD200,000$34.0M2.3%00.0%UnchangedHistory
TERNTerns Pharmaceuticals, Inc.COM750,000$30.3M2.0%+750,000NewHistory
PCVXVaxcyte, Inc.COM650,000$30.0M2.0%+25,000+4.0%AddedHistory
IMCRImmunocore Holdings plcADS850,000$29.5M2.0%00.0%UnchangedHistory
LBRXLB Pharmaceuticals IncCOM SHS1,200,000$26.7M1.8%+70,000+6.2%AddedHistory
DYNDyne Therapeutics, Inc.COM1,250,000$24.4M1.6%−1,150,000−47.9%ReducedHistory
DSGNDesign Therapeutics, Inc.COM2,500,000$23.4M1.6%−1,155,000−31.6%ReducedHistory
MLTXMoonLake ImmunotherapeuticsCLASS A ORD1,750,000$23.1M1.5%+1,750,000NewHistory
ACADAcadia Pharmaceuticals IncCOM850,000$22.7M1.5%+850,000NewHistory
RYTMRhythm Pharmaceuticals, Inc.COM190,000$20.3M1.4%−10,000−5.0%ReducedHistory
TRVITrevi Therapeutics, Inc.COM1,550,000$19.4M1.3%−650,000−29.5%ReducedHistory
CYTKCytokinetics IncCOM NEW300,000$19.1M1.3%+300,000NewHistory
MIRMMirum Pharmaceuticals, Inc.COM225,000$17.8M1.2%+225,000NewHistory
QUREuniQure N.V.SHS675,000$16.2M1.1%+375,000+125.0%AddedHistory
NAMSNewAmsterdam Pharma Co N.V.ORDINARY SHARES450,000$15.8M1.1%+450,000NewHistory
KNSAKiniksa Pharmaceuticals International, plcORD SHS CL A350,000$14.4M1.0%+350,000NewHistory
SLNOSoleno Therapeutics IncCOM300,000$13.9M0.9%+300,000NewHistory
JANXJanux Therapeutics, Inc.COM1,000,000$13.8M0.9%+65,000+7.0%AddedHistory
NERVMinerva Neurosciences, Inc.COM NEW3,311,000$13.3M0.9%+3,311,000NewHistory
VSTMVerastem, Inc.COM NEW1,700,000$13.1M0.9%−2,350,000−58.0%ReducedHistory
DNTHDianthus Therapeutics, Inc.COM315,000$13.0M0.9%+115,000+57.5%AddedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM950,000$11.5M0.8%−500,000−34.5%ReducedHistory
KYMRKymera Therapeutics, Inc.COM130,000$10.1M0.7%−120,000−48.0%ReducedHistory
CLDXCelldex Therapeutics, Inc.COM NEW350,000$9.51M0.6%+350,000NewHistory
NRIXNurix Therapeutics, Inc.COM500,000$9.48M0.6%+500,000NewHistory
CGONCG Oncology, Inc.COM200,000$8.30M0.6%+200,000NewHistory
ACLXArcellx, Inc.COMMON STOCK115,000$7.50M0.5%−50,000−30.3%ReducedHistory
CBIOCrescent Biopharma, Inc.COM600,000$7.12M0.5%00.0%UnchangedHistory
CMPXCompass Therapeutics, Inc.COM1,150,000$6.18M0.4%−900,000−43.9%ReducedHistory
JBIOJade Biosciences, Inc.COM NEW395,000$6.09M0.4%−230,000−36.8%ReducedHistory
TYRATyra Biosciences, Inc.COM210,000$5.52M0.4%+210,000NewHistory
ELVNEnliven Therapeutics, Inc.COM340,000$5.24M0.3%00.0%UnchangedHistory
IMMXImmix Biopharma, Inc.COM1,000,000$5.23M0.3%+1,000,000NewHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS200,000$5.00M0.3%−325,000−61.9%ReducedHistory
NGNENeurogene Inc.COM195,000$4.02M0.3%+195,000NewHistory
IBIOiBio, Inc.COM NEW2,000,000$3.86M0.3%+2,000,000NewHistory
CRVSCorvus Pharmaceuticals, Inc.COM500,000$3.85M0.3%+500,000NewHistory
ORICOric Pharmaceuticals, Inc.COM450,000$3.68M0.2%+450,000NewHistory
DAWNDay One Biopharmaceuticals, Inc.Stock300,000$2.80M0.2%+300,000NewHistory
PHVSPharvaris N.V.COM100,000$2.77M0.2%−50,000−33.3%ReducedHistory
UNCYUnicycive Therapeutics, Inc.COM NEW473,563$2.73M0.2%00.0%UnchangedHistory
GUTSFractyl Health, Inc.COM1,100,000$2.42M0.2%+600,000+120.0%AddedHistory
PTNPalatin Technologies IncCOM NEW140,000$2.15M0.1%+140,000NewHistory
ACRSAclaris Therapeutics, Inc.COM600,000$1.81M0.1%−900,000−60.0%ReducedHistory
VORVor Biopharma Inc.COM NEW100,000$1.31M0.1%+100,000NewHistory
MREOMereo BioPharma Group plcSPON ADS1,850,000$770.9K0.1%+1,350,000+270.0%AddedHistory
SEPNSepterna, Inc.COM23,548$656.5K<0.1%−60,000−71.8%ReducedHistory
DBVTDBV Technologies S.A.SPONSORED ADS25,000$479.3K<0.1%+25,000NewHistory
Nuvation Bio Inc.67080N119*W EXP 07/07/20266,666$22.0K<0.1%00.0%Unchanged–

Options (5)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Logos Global Management LP in Q4 2025
SecurityClassPutsCalls
RVMDRevolution Medicines, Inc.COM–$79.7M
APLSApellis Pharmaceuticals, Inc.COM–$25.1M
RCUSArcus Biosciences, Inc.COM–$25.0M
IDYAIDEAYA Biosciences, Inc.COM–$15.6M
IMTXImmatics N.V.SHS–$8.93M

Sold out since Q3 2025 (11)

Positions held at the end of Q3 2025 that are gone from this filing.

Positions of Logos Global Management LP sold out since Q3 2025
SecurityClassShares in Q3 2025Value in Q3 2025% of portfolio in Q3 2025History
AKROAkero Therapeutics, Inc.COM1,200,000$57.0M5.6%History
ARVNArvinas, Inc.COM5,575,000$47.5M4.7%History
PTGXProtagonist Therapeutics, IncCOM300,000$19.9M2.0%History
KROSKeros Therapeutics, Inc.COM850,000$13.4M1.3%History
COGTCogent Biosciences, Inc.COM500,000$7.18M0.7%History
IMRXImmuneering CorpCLASS A COM950,000$6.65M0.7%History
SRRKScholar Rock Holding CorpCOM175,000$6.52M0.6%History
EPRXEupraxia Pharmaceuticals Inc.COM900,000$5.31M0.5%History
ATXSAstria Therapeutics, Inc.COM500,000$3.64M0.4%History
PEPGPepGen Inc.COM750,000$3.46M0.3%History
ESPREsperion Therapeutics, Inc.COM750,000$1.99M0.2%History