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VR Adviser, LLC

SEC CIK
0001615982
Latest filing
Aug 14, 2026

Holdings in Q2 2025

Holdings as of Jun 30, 2025, filed Aug 14, 2025. Long positions only; changes compare share counts with Q1 2025.

Institution overview
Positions
31
−6 vs. Q1 2025
Portfolio value
$1.33B
+$159.2M (+13.5%) vs. Q1 2025
Filed
Aug 14, 2025
SEC
Holdings of VR Adviser, LLC in Q2 2025
SecurityClassSharesValue% of portfolioShare changeActionHistory
APGEApogee Therapeutics, Inc.COM8,493,321$368.9M27.6%00.0%UnchangedHistory
OCULOcular Therapeutix, IncCOM12,762,462$118.4M8.9%00.0%UnchangedHistory
MTSRMetsera, Inc.COM3,750,662$106.7M8.0%00.0%UnchangedHistory
ELVNEnliven Therapeutics, Inc.COM4,026,331$80.8M6.1%00.0%UnchangedHistory
KALVKalVista Pharmaceuticals, Inc.COM6,728,985$76.1M5.7%+25,000+0.4%AddedHistory
ORICOric Pharmaceuticals, Inc.COM6,596,885$67.0M5.0%+3,414,358+107.3%AddedHistory
VRDNViridian Therapeutics, Inc.COM3,882,709$54.3M4.1%00.0%UnchangedHistory
ORKAOruka Therapeutics, Inc.COM4,148,428$46.5M3.5%00.0%UnchangedHistory
SYRESpyre Therapeutics, Inc.COM NEW2,685,448$40.2M3.0%00.0%UnchangedHistory
PHVSPharvaris N.V.COM2,047,620$36.0M2.7%−1,065,100−34.2%ReducedHistory
COGTCogent Biosciences, Inc.COM4,755,411$34.1M2.6%−929,000−16.3%ReducedHistory
JBIOJade Biosciences, Inc.COM NEW3,220,364$32.2M2.4%+3,220,364NewHistory
CTMXCytomX Therapeutics, Inc.COM13,969,882$31.7M2.4%+13,969,882NewHistory
CDTXCidara Therapeutics, Inc.COM NEW639,088$31.1M2.3%−412,430−39.2%ReducedHistory
UPBUpstream Bio, Inc.COM2,295,319$25.2M1.9%00.0%UnchangedHistory
ERASErasca, Inc.COM17,857,083$22.7M1.7%+1,640,867+10.1%AddedHistory
CBIOCrescent Biopharma, Inc.COM1,387,864$22.4M1.7%+1,387,864NewHistory
DYNDyne Therapeutics, Inc.COM2,173,913$20.7M1.6%00.0%UnchangedHistory
SVRASavara IncCOM8,884,263$20.3M1.5%+5,626,624+172.7%AddedHistory
DNTHDianthus Therapeutics, Inc.COM1,000,000$18.6M1.4%−744,373−42.7%ReducedHistory
ENGNenGene Therapeutics Inc.COM5,046,414$18.4M1.4%00.0%UnchangedHistory
ATXSAstria Therapeutics, Inc.COM2,457,348$13.2M1.0%00.0%UnchangedHistory
CGEMCullinan Therapeutics, Inc.COM1,379,965$10.4M0.8%00.0%UnchangedHistory
ABVXAbivax S.A.SPONSORED ADS1,345,780$10.3M0.8%00.0%UnchangedHistory
FRNMFreenome, Inc.CL A ORD SHS750,000$7.96M0.6%00.0%UnchangedHistory
SEPNSepterna, Inc.COM540,453$5.71M0.4%+540,453NewHistory
SRZNSurrozen, Inc.COM NEW632,931$5.66M0.4%00.0%UnchangedHistory
ZURAZura Bio LtdCLASS A ORD SHS4,631,216$4.86M0.4%−391,950−7.8%ReducedHistory
ARTVArtiva Biotherapeutics, Inc.COM1,609,569$2.43M0.2%00.0%UnchangedHistory
CASIFCASI Pharmaceuticals, Inc.ORD SHS987,259$1.16M0.1%00.0%UnchangedHistory
TENXTenax Therapeutics, Inc.COM NEW98,564$567.7K<0.1%−109,769−52.7%ReducedHistory

Sold out since Q1 2025 (10)

Positions held at the end of Q1 2025 that are gone from this filing.

Positions of VR Adviser, LLC sold out since Q1 2025
SecurityClassShares in Q1 2025Value in Q1 2025% of portfolio in Q1 2025History
PRAXPraxis Precision Medicines, Inc.COM NEW989,985$37.5M3.2%History
SLDBSolid Biosciences Inc.COM NEW2,481,400$9.18M0.8%History
TRVITrevi Therapeutics, Inc.COM615,506$3.87M0.3%History
APLTApplied Therapeutics, Inc.COM5,567,709$2.72M0.2%History
FDMT4D Molecular Therapeutics, Inc.COM677,600$2.19M0.2%History
MRSNMersana Therapeutics, Inc.COM3,574,325$1.23M0.1%History
IPSCCentury Therapeutics, Inc.COM2,498,069$1.19M0.1%History
TNYATenaya Therapeutics, Inc.COM1,555,556$886.8K0.1%History
CBIOCrescent Biopharma, Inc.COM3,000,000$630.0K0.1%History
TILInstil Bio, Inc.COM NEW33,177$576.0K<0.1%History