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VR Adviser, LLC

SEC CIK
0001615982
Latest filing
Aug 14, 2026

Holdings in Q3 2025

Holdings as of Sep 30, 2025, filed Nov 14, 2025. Long positions only; changes compare share counts with Q2 2025.

Institution overview
Positions
33
+2 vs. Q2 2025
Portfolio value
$1.78B
+$442.3M (+33.1%) vs. Q2 2025
Filed
Nov 14, 2025
SEC
Holdings of VR Adviser, LLC in Q3 2025
SecurityClassSharesValue% of portfolioShare changeActionHistory
APGEApogee Therapeutics, Inc.COM8,493,321$337.4M19.0%00.0%UnchangedHistory
MTSRMetsera, Inc.COM3,750,662$196.3M11.0%00.0%UnchangedHistory
OCULOcular Therapeutix, IncCOM13,161,462$153.9M8.7%+399,000+3.1%AddedHistory
CDTXCidara Therapeutics, Inc.COM NEW946,788$90.7M5.1%+307,700+48.1%AddedHistory
VRDNViridian Therapeutics, Inc.COM3,882,709$83.8M4.7%00.0%UnchangedHistory
KALVKalVista Pharmaceuticals, Inc.COM6,728,985$82.0M4.6%00.0%UnchangedHistory
ORKAOruka Therapeutics, Inc.COM4,148,428$79.8M4.5%00.0%UnchangedHistory
ORICOric Pharmaceuticals, Inc.COM6,596,885$79.2M4.5%00.0%UnchangedHistory
ELVNEnliven Therapeutics, Inc.COM3,226,331$66.0M3.7%−800,000−19.9%ReducedHistory
COGTCogent Biosciences, Inc.COM4,000,000$57.4M3.2%−755,411−15.9%ReducedHistory
CTMXCytomX Therapeutics, Inc.COM15,561,500$49.6M2.8%+1,591,618+11.4%AddedHistory
ABVXAbivax S.A.SPONSORED ADS576,729$49.0M2.8%−769,051−57.1%ReducedHistory
SVRASavara IncCOM12,681,043$45.3M2.5%+3,796,780+42.7%AddedHistory
SYRESpyre Therapeutics, Inc.COM NEW2,685,448$45.0M2.5%00.0%UnchangedHistory
ERASErasca, Inc.COM17,857,083$38.9M2.2%00.0%UnchangedHistory
DNTHDianthus Therapeutics, Inc.COM960,803$37.8M2.1%−39,197−3.9%ReducedHistory
ENGNenGene Therapeutics Inc.COM5,046,414$34.5M1.9%00.0%UnchangedHistory
MAZEMaze Therapeutics, Inc.COM1,230,769$31.9M1.8%+1,230,769NewHistory
JBIOJade Biosciences, Inc.COM NEW3,220,364$27.8M1.6%00.0%UnchangedHistory
DYNDyne Therapeutics, Inc.COM2,173,913$27.5M1.5%00.0%UnchangedHistory
VORVor Biopharma Inc.COM NEW499,966$24.4M1.4%+499,966NewHistory
UPBUpstream Bio, Inc.COM1,169,298$22.0M1.2%−1,126,021−49.1%ReducedHistory
ZURAZura Bio LtdCLASS A ORD SHS4,631,216$20.1M1.1%00.0%UnchangedHistory
ATXSAstria Therapeutics, Inc.COM2,457,348$17.9M1.0%00.0%UnchangedHistory
PHVSPharvaris N.V.COM674,599$16.8M0.9%−1,373,021−67.1%ReducedHistory
CBIOCrescent Biopharma, Inc.COM1,387,864$16.5M0.9%00.0%UnchangedHistory
SEPNSepterna, Inc.COM610,808$11.5M0.6%+70,355+13.0%AddedHistory
CGEMCullinan Therapeutics, Inc.COM1,379,965$8.18M0.5%00.0%UnchangedHistory
SRZNSurrozen, Inc.COM NEW632,931$8.16M0.5%00.0%UnchangedHistory
FRNMFreenome, Inc.CL A ORD SHS750,000$7.95M0.4%00.0%UnchangedHistory
ARTVArtiva Biotherapeutics, Inc.COM1,609,569$4.62M0.3%00.0%UnchangedHistory
TENXTenax Therapeutics, Inc.COM NEW437,708$3.33M0.2%+339,144+344.1%AddedHistory
CASIFCASI Pharmaceuticals, Inc.ORD SHS987,259$1.64M0.1%00.0%UnchangedHistory