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VR Adviser, LLC

SEC CIK
0001615982
Latest filing
Aug 14, 2026

Holdings in Q1 2025

Holdings as of Mar 31, 2025, filed May 15, 2025. Long positions only; changes compare share counts with Q4 2024.

Institution overview
Positions
37
0 vs. Q4 2024
Portfolio value
$1.18B
−$282.2M (−19.4%) vs. Q4 2024
Filed
May 15, 2025
SEC
Holdings of VR Adviser, LLC in Q1 2025
SecurityClassSharesValue% of portfolioShare changeActionHistory
APGEApogee Therapeutics, Inc.COM8,493,321$317.3M27.0%00.0%UnchangedHistory
MTSRMetsera, Inc.COM3,750,662$102.1M8.7%+3,750,662NewHistory
OCULOcular Therapeutix, IncCOM12,762,462$93.5M8.0%00.0%UnchangedHistory
ELVNEnliven Therapeutics, Inc.COM4,026,331$79.2M6.7%00.0%UnchangedHistory
KALVKalVista Pharmaceuticals, Inc.COM6,703,985$77.4M6.6%+454,254+7.3%AddedHistory
VRDNViridian Therapeutics, Inc.COM3,882,709$52.3M4.5%00.0%UnchangedHistory
PHVSPharvaris N.V.COM3,112,720$48.9M4.2%−107,410−3.3%ReducedHistory
SYRESpyre Therapeutics, Inc.COM NEW2,685,448$43.3M3.7%00.0%UnchangedHistory
ORKAOruka Therapeutics, Inc.COM4,148,428$42.6M3.6%+862,808+26.3%AddedHistory
PRAXPraxis Precision Medicines, Inc.COM NEW989,985$37.5M3.2%00.0%UnchangedHistory
COGTCogent Biosciences, Inc.COM5,684,411$34.0M2.9%00.0%UnchangedHistory
DNTHDianthus Therapeutics, Inc.COM1,744,373$31.6M2.7%00.0%UnchangedHistory
DYNDyne Therapeutics, Inc.COM2,173,913$22.7M1.9%00.0%UnchangedHistory
CDTXCidara Therapeutics, Inc.COM NEW1,051,518$22.6M1.9%+285,795+37.3%AddedHistory
ENGNenGene Therapeutics Inc.COM5,046,414$22.6M1.9%00.0%UnchangedHistory
ERASErasca, Inc.COM16,216,216$22.2M1.9%00.0%UnchangedHistory
ORICOric Pharmaceuticals, Inc.COM3,182,527$17.8M1.5%−1,212,000−27.6%ReducedHistory
UPBUpstream Bio, Inc.COM2,295,319$14.0M1.2%00.0%UnchangedHistory
ATXSAstria Therapeutics, Inc.COM2,457,348$13.1M1.1%00.0%UnchangedHistory
CGEMCullinan Therapeutics, Inc.COM1,379,965$10.4M0.9%00.0%UnchangedHistory
SLDBSolid Biosciences Inc.COM NEW2,481,400$9.18M0.8%+2,481,400NewHistory
SVRASavara IncCOM3,257,639$9.02M0.8%+3,257,639NewHistory
ABVXAbivax S.A.SPONSORED ADS1,345,780$8.41M0.7%00.0%UnchangedHistory
FRNMFreenome, Inc.CL A ORD SHS750,000$7.72M0.7%00.0%UnchangedHistory
SRZNSurrozen, Inc.COM NEW632,931$7.38M0.6%+632,931NewHistory
ZURAZura Bio LtdCLASS A ORD SHS5,023,166$6.48M0.6%+3,000,000+148.3%AddedHistory
ARTVArtiva Biotherapeutics, Inc.COM1,609,569$4.83M0.4%00.0%UnchangedHistory
TRVITrevi Therapeutics, Inc.COM615,506$3.87M0.3%−650,951−51.4%ReducedHistory
APLTApplied Therapeutics, Inc.COM5,567,709$2.72M0.2%−4,422,882−44.3%ReducedHistory
FDMT4D Molecular Therapeutics, Inc.COM677,600$2.19M0.2%−2,274,771−77.0%ReducedHistory
CASIFCASI Pharmaceuticals, Inc.ORD SHS987,259$2.13M0.2%00.0%UnchangedHistory
TENXTenax Therapeutics, Inc.COM NEW208,333$1.36M0.1%00.0%UnchangedHistory
MRSNMersana Therapeutics, Inc.COM3,574,325$1.23M0.1%−6,683,465−65.2%ReducedHistory
IPSCCentury Therapeutics, Inc.COM2,498,069$1.19M0.1%−1,459,117−36.9%ReducedHistory
TNYATenaya Therapeutics, Inc.COM1,555,556$886.8K0.1%00.0%UnchangedHistory
CBIOCrescent Biopharma, Inc.COM3,000,000$630.0K0.1%00.0%UnchangedHistory
TILInstil Bio, Inc.COM NEW33,177$576.0K<0.1%00.0%UnchangedHistory

Sold out since Q4 2024 (4)

Positions held at the end of Q4 2024 that are gone from this filing.

Positions of VR Adviser, LLC sold out since Q4 2024
SecurityClassShares in Q4 2024Value in Q4 2024% of portfolio in Q4 2024History
MRUSMerus N.V.COM592,411$24.9M1.7%History
AQSTAquestive Therapeutics, Inc.COM2,629,786$9.36M0.6%History
TERNTerns Pharmaceuticals, Inc.COM1,077,090$5.97M0.4%History
TSHATaysha Gene Therapies, Inc.COM SHS3,225,180$5.58M0.4%History