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VR Adviser, LLC

SEC CIK
0001615982
Latest filing
Aug 14, 2026

Holdings in Q4 2024

Holdings as of Dec 31, 2024, filed Feb 14, 2025. Long positions only; changes compare share counts with Q3 2024.

Institution overview
Positions
37
−1 vs. Q3 2024
Portfolio value
$1.46B
−$451.8M (−23.7%) vs. Q3 2024
Filed
Feb 14, 2025
SEC
Holdings of VR Adviser, LLC in Q4 2024
SecurityClassSharesValue% of portfolioShare changeActionHistory
APGEApogee Therapeutics, Inc.COM8,493,321$384.7M26.4%00.0%UnchangedHistory
OCULOcular Therapeutix, IncCOM12,762,462$109.0M7.5%00.0%UnchangedHistory
ELVNEnliven Therapeutics, Inc.COM4,026,331$90.6M6.2%00.0%UnchangedHistory
PRAXPraxis Precision Medicines, Inc.COM NEW989,985$76.2M5.2%+283,854+40.2%AddedHistory
VRDNViridian Therapeutics, Inc.COM3,882,709$74.4M5.1%00.0%UnchangedHistory
ORKAOruka Therapeutics, Inc.COM3,285,620$63.7M4.4%+200,000+6.5%AddedHistory
SYRESpyre Therapeutics, Inc.COM NEW2,685,448$62.5M4.3%00.0%UnchangedHistory
PHVSPharvaris N.V.COM3,220,130$61.7M4.2%−175,476−5.2%ReducedHistory
KALVKalVista Pharmaceuticals, Inc.COM6,249,731$52.9M3.6%00.0%UnchangedHistory
DYNDyne Therapeutics, Inc.COM2,173,913$51.2M3.5%00.0%UnchangedHistory
COGTCogent Biosciences, Inc.COM5,684,411$44.3M3.0%+2440.0%AddedHistory
ERASErasca, Inc.COM16,216,216$40.7M2.8%00.0%UnchangedHistory
DNTHDianthus Therapeutics, Inc.COM1,744,373$38.0M2.6%00.0%UnchangedHistory
UPBUpstream Bio, Inc.COM2,295,319$37.7M2.6%+2,295,319NewHistory
ORICOric Pharmaceuticals, Inc.COM4,394,527$35.5M2.4%00.0%UnchangedHistory
ENGNenGene Therapeutics Inc.COM5,046,414$33.6M2.3%+1,480,573+41.5%AddedHistory
MRUSMerus N.V.COM592,411$24.9M1.7%−315,552−34.8%ReducedHistory
ATXSAstria Therapeutics, Inc.COM2,457,348$22.0M1.5%−1,001,297−29.0%ReducedHistory
CDTXCidara Therapeutics, Inc.COM NEW765,723$20.6M1.4%+765,723NewHistory
CGEMCullinan Therapeutics, Inc.COM1,379,965$16.8M1.2%00.0%UnchangedHistory
FDMT4D Molecular Therapeutics, Inc.COM2,952,371$16.4M1.1%−1,447,629−32.9%ReducedHistory
ARTVArtiva Biotherapeutics, Inc.COM1,609,569$16.2M1.1%00.0%UnchangedHistory
MRSNMersana Therapeutics, Inc.COM10,257,790$14.7M1.0%−1,070,210−9.4%ReducedHistory
ABVXAbivax S.A.SPONSORED ADS1,345,780$9.85M0.7%00.0%UnchangedHistory
AQSTAquestive Therapeutics, Inc.COM2,629,786$9.36M0.6%−2,925,769−52.7%ReducedHistory
APLTApplied Therapeutics, Inc.COM9,990,591$8.55M0.6%+165,591+1.7%AddedHistory
FRNMFreenome, Inc.CL A ORD SHS750,000$7.63M0.5%00.0%UnchangedHistory
TERNTerns Pharmaceuticals, Inc.COM1,077,090$5.97M0.4%−2,332,968−68.4%ReducedHistory
TSHATaysha Gene Therapies, Inc.COM SHS3,225,180$5.58M0.4%−5,774,820−64.2%ReducedHistory
TRVITrevi Therapeutics, Inc.COM1,266,457$5.22M0.4%−2,156,199−63.0%ReducedHistory
ZURAZura Bio LtdCLASS A ORD SHS2,023,166$5.06M0.3%00.0%UnchangedHistory
IPSCCentury Therapeutics, Inc.COM3,957,186$4.00M0.3%−1,432,073−26.6%ReducedHistory
CASIFCASI Pharmaceuticals, Inc.ORD SHS987,259$2.79M0.2%00.0%UnchangedHistory
TNYATenaya Therapeutics, Inc.COM1,555,556$2.22M0.2%00.0%UnchangedHistory
TENXTenax Therapeutics, Inc.COM NEW208,333$1.29M0.1%00.0%UnchangedHistory
CBIOCrescent Biopharma, Inc.COM3,000,000$747.0K0.1%+3,000,000NewHistory
TILInstil Bio, Inc.COM NEW33,177$633.3K<0.1%00.0%UnchangedHistory

Sold out since Q3 2024 (4)

Positions held at the end of Q3 2024 that are gone from this filing.

Positions of VR Adviser, LLC sold out since Q3 2024
SecurityClassShares in Q3 2024Value in Q3 2024% of portfolio in Q3 2024History
EWTXEdgewise Therapeutics, Inc.COM1,000,000$26.7M1.4%History
ARVNArvinas, Inc.COM454,450$11.2M0.6%History
ADVMAdverum Biotechnologies, Inc.COM NEW1,467,048$10.3M0.5%History
CABACabaletta Bio, Inc.COM1,563,952$7.38M0.4%History