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VR Adviser, LLC

SEC CIK
0001615982
Latest filing
Aug 14, 2026

Holdings in Q2 2025

Holdings as of Jun 30, 2025, filed Aug 14, 2025. Long positions only; changes compare share counts with Q1 2025.

Institution overview
Positions
31
−6 vs. Q1 2025
Portfolio value
$1.33B
+$159.2M (+13.5%) vs. Q1 2025
Filed
Aug 14, 2025
SEC
Holdings of VR Adviser, LLC in Q2 2025
SecurityClassSharesValue% of portfolioShare changeActionHistory
TENXTenax Therapeutics, Inc.COM NEW98,564$567.7K<0.1%−109,769−52.7%ReducedHistory
CASIFCASI Pharmaceuticals, Inc.ORD SHS987,259$1.16M0.1%00.0%UnchangedHistory
ARTVArtiva Biotherapeutics, Inc.COM1,609,569$2.43M0.2%00.0%UnchangedHistory
ZURAZura Bio LtdCLASS A ORD SHS4,631,216$4.86M0.4%−391,950−7.8%ReducedHistory
SRZNSurrozen, Inc.COM NEW632,931$5.66M0.4%00.0%UnchangedHistory
SEPNSepterna, Inc.COM540,453$5.71M0.4%+540,453NewHistory
FRNMFreenome, Inc.CL A ORD SHS750,000$7.96M0.6%00.0%UnchangedHistory
ABVXAbivax S.A.SPONSORED ADS1,345,780$10.3M0.8%00.0%UnchangedHistory
CGEMCullinan Therapeutics, Inc.COM1,379,965$10.4M0.8%00.0%UnchangedHistory
ATXSAstria Therapeutics, Inc.COM2,457,348$13.2M1.0%00.0%UnchangedHistory
ENGNenGene Therapeutics Inc.COM5,046,414$18.4M1.4%00.0%UnchangedHistory
DNTHDianthus Therapeutics, Inc.COM1,000,000$18.6M1.4%−744,373−42.7%ReducedHistory
SVRASavara IncCOM8,884,263$20.3M1.5%+5,626,624+172.7%AddedHistory
DYNDyne Therapeutics, Inc.COM2,173,913$20.7M1.6%00.0%UnchangedHistory
CBIOCrescent Biopharma, Inc.COM1,387,864$22.4M1.7%+1,387,864NewHistory
ERASErasca, Inc.COM17,857,083$22.7M1.7%+1,640,867+10.1%AddedHistory
UPBUpstream Bio, Inc.COM2,295,319$25.2M1.9%00.0%UnchangedHistory
CDTXCidara Therapeutics, Inc.COM NEW639,088$31.1M2.3%−412,430−39.2%ReducedHistory
CTMXCytomX Therapeutics, Inc.COM13,969,882$31.7M2.4%+13,969,882NewHistory
JBIOJade Biosciences, Inc.COM NEW3,220,364$32.2M2.4%+3,220,364NewHistory
COGTCogent Biosciences, Inc.COM4,755,411$34.1M2.6%−929,000−16.3%ReducedHistory
PHVSPharvaris N.V.COM2,047,620$36.0M2.7%−1,065,100−34.2%ReducedHistory
SYRESpyre Therapeutics, Inc.COM NEW2,685,448$40.2M3.0%00.0%UnchangedHistory
ORKAOruka Therapeutics, Inc.COM4,148,428$46.5M3.5%00.0%UnchangedHistory
VRDNViridian Therapeutics, Inc.COM3,882,709$54.3M4.1%00.0%UnchangedHistory
ORICOric Pharmaceuticals, Inc.COM6,596,885$67.0M5.0%+3,414,358+107.3%AddedHistory
KALVKalVista Pharmaceuticals, Inc.COM6,728,985$76.1M5.7%+25,000+0.4%AddedHistory
ELVNEnliven Therapeutics, Inc.COM4,026,331$80.8M6.1%00.0%UnchangedHistory
MTSRMetsera, Inc.COM3,750,662$106.7M8.0%00.0%UnchangedHistory
OCULOcular Therapeutix, IncCOM12,762,462$118.4M8.9%00.0%UnchangedHistory
APGEApogee Therapeutics, Inc.COM8,493,321$368.9M27.6%00.0%UnchangedHistory

Sold out since Q1 2025 (10)

Positions held at the end of Q1 2025 that are gone from this filing.

Positions of VR Adviser, LLC sold out since Q1 2025
SecurityClassShares in Q1 2025Value in Q1 2025% of portfolio in Q1 2025History
PRAXPraxis Precision Medicines, Inc.COM NEW989,985$37.5M3.2%History
SLDBSolid Biosciences Inc.COM NEW2,481,400$9.18M0.8%History
TRVITrevi Therapeutics, Inc.COM615,506$3.87M0.3%History
APLTApplied Therapeutics, Inc.COM5,567,709$2.72M0.2%History
FDMT4D Molecular Therapeutics, Inc.COM677,600$2.19M0.2%History
MRSNMersana Therapeutics, Inc.COM3,574,325$1.23M0.1%History
IPSCCentury Therapeutics, Inc.COM2,498,069$1.19M0.1%History
TNYATenaya Therapeutics, Inc.COM1,555,556$886.8K0.1%History
CBIOCrescent Biopharma, Inc.COM3,000,000$630.0K0.1%History
TILInstil Bio, Inc.COM NEW33,177$576.0K<0.1%History