Sphera Funds Management Ltd.
- SEC CIK
- 0001496201
- Latest filing
- Aug 14, 2026
Holdings in Q4 2024
Holdings as of Dec 31, 2024, filed Feb 14, 2025. Long positions only; changes compare share counts with Q3 2024.
- Positions
- 103
- −5 vs. Q3 2024
- Portfolio value
- $541.4M
- −$69.8M (−11.4%) vs. Q3 2024
| Security | Class | Shares | Value | % of portfolio | Share change | Action | History |
|---|---|---|---|---|---|---|---|
| TEVATeva Pharmaceutical Industries Ltd | SPONSORED ADS | 1,569,181 | $34.6M | 6.4% | −561,035−26.3% | Reduced | History |
| BBIOBridgeBio Pharma, Inc. | COM | 905,279 | $24.8M | 4.6% | +62,635+7.4% | Added | History |
| SNYSanofi | SPONSORED ADR | 384,515 | $18.5M | 3.4% | −25,000−6.1% | Reduced | History |
| SNDXSyndax Pharmaceuticals Inc | COM | 1,381,241 | $18.3M | 3.4% | +346,395+33.5% | Added | History |
| AZNAstraZeneca PLC | SPONSORED ADR | 225,060 | $14.7M | 2.7% | +35,000+18.4% | Added | History |
| AMZNAmazon Com Inc | Stock | 62,607 | $13.7M | 2.5% | −43,000−40.7% | Reduced | History |
| NVMINova Ltd. | COM | 68,146 | $13.4M | 2.5% | +16,186+31.2% | Added | History |
| METAMeta Platforms, Inc. | Stock | 21,001 | $12.3M | 2.3% | −8,315−28.4% | Reduced | History |
| SRPTSarepta Therapeutics, Inc. | COM | 98,921 | $12.0M | 2.2% | −26,925−21.4% | Reduced | History |
| CLDXCelldex Therapeutics, Inc. | COM NEW | 474,103 | $12.0M | 2.2% | +55,000+13.1% | Added | History |
| ELDNEledon Pharmaceuticals, Inc. | COM | 2,551,619 | $10.5M | 1.9% | +1,254,298+96.7% | Added | History |
| LLYEli Lilly & Co | Stock | 13,190 | $10.2M | 1.9% | 00.0% | Unchanged | History |
| JNJJohnson & Johnson | Stock | 69,831 | $10.1M | 1.9% | 00.0% | Unchanged | History |
| RAREUltragenyx Pharmaceutical Inc. | COM | 228,776 | $9.62M | 1.8% | +33,427+17.1% | Added | History |
| MSFTMicrosoft Corp | Stock | 22,327 | $9.41M | 1.7% | −11,100−33.2% | Reduced | History |
| MRVLMarvell Technology, Inc. | COM | 78,611 | $8.68M | 1.6% | −9,000−10.3% | Reduced | History |
| TSEMTower Semiconductor Ltd | SHS NEW | 166,149 | $8.56M | 1.6% | −43,292−20.7% | Reduced | History |
| NVONovo Nordisk A S | ADR | 98,080 | $8.44M | 1.6% | +20,000+25.6% | Added | History |
| WIXWix.com Ltd. | SHS | 39,253 | $8.42M | 1.6% | +5,000+14.6% | Added | History |
| GOOGAlphabet Inc. | Stock | 43,500 | $8.28M | 1.5% | +43,500 | New | History |
| PHVSPharvaris N.V. | COM | 388,183 | $7.44M | 1.4% | −51,109−11.6% | Reduced | History |
| NICENICE Ltd. | SPONSORED ADR | 42,500 | $7.22M | 1.3% | −35,861−45.8% | Reduced | History |
| CYTKCytokinetics Inc | COM NEW | 153,021 | $7.20M | 1.3% | −72,000−32.0% | Reduced | History |
| PRAXPraxis Precision Medicines, Inc. | COM NEW | 91,583 | $7.05M | 1.3% | −60,724−39.9% | Reduced | History |
| CHKPCheck Point Software Technologies Ltd | ORD | 35,635 | $6.65M | 1.2% | −4,580−11.4% | Reduced | History |
| APLSApellis Pharmaceuticals, Inc. | COM | 206,251 | $6.58M | 1.2% | −9,622−4.5% | Reduced | History |
| IMTXImmatics N.V. | SHS | 921,111 | $6.55M | 1.2% | +200,000+27.7% | Added | History |
| ANNXAnnexon, Inc. | COM | 1,243,039 | $6.38M | 1.2% | +1,243,039 | New | History |
| ABBVAbbVie Inc. | Stock | 34,256 | $6.09M | 1.1% | −3,744−9.9% | Reduced | History |
| MRKMerck & Co., Inc. | Stock | 59,600 | $5.93M | 1.1% | 00.0% | Unchanged | History |
| BHVNBiohaven Ltd. | COM | 156,494 | $5.85M | 1.1% | +23,171+17.4% | Added | History |
| RZLTRezolute, Inc. | COM NEW | 1,165,895 | $5.71M | 1.1% | −31,043−2.6% | Reduced | History |
| FROGJFrog Ltd | Stock | 190,381 | $5.60M | 1.0% | +70,000+58.1% | Added | History |
| DYNDyne Therapeutics, Inc. | COM | 236,262 | $5.57M | 1.0% | +179,758+318.1% | Added | History |
| MRUSMerus N.V. | COM | 130,532 | $5.49M | 1.0% | −17,101−11.6% | Reduced | History |
| NTLAIntellia Therapeutics, Inc. | COM | 466,080 | $5.43M | 1.0% | +175,000+60.1% | Added | History |
| ORAOrmat Technologies, Inc. | COM | 79,000 | $5.35M | 1.0% | +79,000 | New | History |
| KURAKura Oncology, Inc. | COM | 610,087 | $5.31M | 1.0% | 00.0% | Unchanged | History |
| ACADAcadia Pharmaceuticals Inc | COM | 288,539 | $5.29M | 1.0% | +36,000+14.3% | Added | History |
| SEDGSolaredge Technologies, Inc. | COM | 375,000 | $5.10M | 0.9% | +375,000 | New | History |
| Ormat Technologies, Inc.686688AC6 | DEBT 2.500% 7/1 | 5,037,000 | $5.02M | 0.9% | 00.0% | Unchanged | – |
| NVSNovartis AG | ADR | 50,000 | $4.87M | 0.9% | 00.0% | Unchanged | History |
| HELPHelus Pharma Inc. | COM NEW | 538,111 | $4.75M | 0.9% | −395,114−42.3% | Reduced | History |
| SKYESkye Bioscience, Inc. | COM NEW | 1,564,628 | $4.43M | 0.8% | +1,106+0.1% | Added | History |
| GSKGSK plc | ADR | 130,000 | $4.40M | 0.8% | +30,000+30.0% | Added | History |
| ETNB89bio, Inc. | COM | 556,532 | $4.35M | 0.8% | +19,985+3.7% | Added | History |
| VIRVir Biotechnology, Inc. | COM | 581,829 | $4.27M | 0.8% | +488,500+523.4% | Added | History |
| DAWNDay One Biopharmaceuticals, Inc. | Stock | 334,987 | $4.24M | 0.8% | −12,640−3.6% | Reduced | History |
| VKTXViking Therapeutics, Inc. | COM | 103,270 | $4.16M | 0.8% | −29,796−22.4% | Reduced | History |
| PLRXPliant Therapeutics, Inc. | COM | 297,362 | $3.92M | 0.7% | 00.0% | Unchanged | History |
| AVGOBroadcom Inc. | Stock | 16,880 | $3.91M | 0.7% | 00.0% | Unchanged | History |
| SRRKScholar Rock Holding Corp | COM | 90,193 | $3.90M | 0.7% | −76,673−45.9% | Reduced | History |
| TVTXTravere Therapeutics, Inc. | COM | 220,700 | $3.84M | 0.7% | +220,700 | New | History |
| ENGNenGene Therapeutics Inc. | COM | 560,000 | $3.72M | 0.7% | +560,000 | New | History |
| SVRASavara Inc | COM | 1,211,533 | $3.72M | 0.7% | +648,426+115.2% | Added | History |
| ARWRArrowhead Pharmaceuticals, Inc. | COM | 197,550 | $3.71M | 0.7% | +197,550 | New | History |
| JANXJanux Therapeutics, Inc. | COM | 68,333 | $3.66M | 0.7% | +68,333 | New | History |
| ACOGAlpha Cognition Inc. | COM NEW | 620,000 | $3.65M | 0.7% | +620,000 | New | History |
| SWTXSpringWorks Therapeutics, Inc. | COM | 100,000 | $3.61M | 0.7% | +100,000 | New | History |
| BIIBBiogen Inc. | COM | 22,738 | $3.48M | 0.6% | −1,717−7.0% | Reduced | History |
| ENPHEnphase Energy, Inc. | Stock | 50,198 | $3.45M | 0.6% | −14,026−21.8% | Reduced | History |
| RCKTRocket Pharmaceuticals, Inc. | COM | 271,792 | $3.42M | 0.6% | +40,000+17.3% | Added | History |
| INZYInozyme Pharma, Inc. | COM | 1,191,140 | $3.30M | 0.6% | 00.0% | Unchanged | History |
| CAMTCamtek Ltd | ORD | 36,287 | $2.93M | 0.5% | 00.0% | Unchanged | History |
| JSPRJasper Therapeutics, Inc. | COM NEW | 135,720 | $2.90M | 0.5% | −53,550−28.3% | Reduced | History |
| CRVSCorvus Pharmaceuticals, Inc. | COM | 500,491 | $2.68M | 0.5% | +500,491 | New | History |
| CRGXCARGO Therapeutics, Inc. | COM | 179,674 | $2.59M | 0.5% | −10,832−5.7% | Reduced | History |
| WDAYWorkday, Inc. | CL A | 10,000 | $2.58M | 0.5% | +2,500+33.3% | Added | History |
| VIGLVigil Neuroscience, Inc. | COM | 1,502,429 | $2.55M | 0.5% | −145,175−8.8% | Reduced | History |
| NTRNutrien Ltd. | COM | 55,894 | $2.50M | 0.5% | +15,164+37.2% | Added | History |
| CGEMCullinan Therapeutics, Inc. | COM | 205,000 | $2.50M | 0.5% | +19,129+10.3% | Added | History |
| PFEPfizer Inc | Stock | 90,000 | $2.39M | 0.4% | 00.0% | Unchanged | History |
| VTGNVistagen Therapeutics, Inc. | COM | 808,550 | $2.39M | 0.4% | 00.0% | Unchanged | History |
| MLYSMineralys Therapeutics, Inc. | COM | 190,672 | $2.35M | 0.4% | −81,800−30.0% | Reduced | History |
| IONSIonis Pharmaceuticals Inc | COM | 63,821 | $2.23M | 0.4% | 00.0% | Unchanged | History |
| VTYXVentyx Biosciences, Inc. | COM | 1,012,749 | $2.22M | 0.4% | 00.0% | Unchanged | History |
| ORICOric Pharmaceuticals, Inc. | COM | 273,213 | $2.20M | 0.4% | +144,817+112.8% | Added | History |
| CMMBChemomab Therapeutics Ltd. | SPONSORED ADS | 1,214,575 | $2.20M | 0.4% | 00.0% | Unchanged | History |
| XENEXenon Pharmaceuticals Inc. | COM | 52,097 | $2.04M | 0.4% | +52,097 | New | History |
| PMNProMIS Neurosciences Inc. | COM | 1,929,297 | $1.83M | 0.3% | 00.0% | Unchanged | History |
| UBERUber Technologies, Inc | Stock | 30,000 | $1.81M | 0.3% | +30,000 | New | History |
| LRMRLarimar Therapeutics, Inc. | COM | 455,604 | $1.76M | 0.3% | +41,126+9.9% | Added | History |
| ZURAZura Bio Ltd | CLASS A ORD SHS | 690,718 | $1.73M | 0.3% | −48,000−6.5% | Reduced | History |
| SHL Telemedicine Ltd78423T200 | ADS | 632,456 | $1.68M | 0.3% | 00.0% | Unchanged | – |
| CATXPerspective Therapeutics, Inc. | COM NEW | 460,247 | $1.47M | 0.3% | −129,048−21.9% | Reduced | History |
| ATXSAstria Therapeutics, Inc. | COM | 139,800 | $1.25M | 0.2% | +3,218+2.4% | Added | History |
| BMYBristol Myers Squibb Co | Stock | 20,000 | $1.13M | 0.2% | +20,000 | New | History |
| MRSNMersana Therapeutics, Inc. | COM | 690,272 | $987.1K | 0.2% | +690,272 | New | History |
| ALMSAlumis Inc. | COM | 125,000 | $982.5K | 0.2% | 00.0% | Unchanged | History |
| HOWLWerewolf Therapeutics, Inc. | COM | 626,810 | $927.7K | 0.2% | 00.0% | Unchanged | History |
| APREAprea Therapeutics, Inc. | COM NEW | 270,000 | $888.3K | 0.2% | 00.0% | Unchanged | History |
| PERIPerion Network Ltd. | SHS NEW | 102,612 | $869.1K | 0.2% | −131,997−56.3% | Reduced | History |
| OKUROnKure Therapeutics, Inc. | COM CL A | 87,354 | $751.2K | 0.1% | +87,354 | New | History |
| KZRKezar Life Sciences, Inc. | COM | 108,473 | $728.9K | 0.1% | +87,956+428.7% | AddedConverted for a 1-for-10 split | History |
| FATEFate Therapeutics Inc | COM | 397,177 | $655.3K | 0.1% | +397,177 | New | History |
| ALECAlector, Inc. | COM | 324,639 | $613.6K | 0.1% | −295,361−47.6% | Reduced | History |
| ELEVElevation Acquisition Group Inc. | COM | 1,018,562 | $573.0K | 0.1% | −61,200−5.7% | Reduced | History |
| CLYMClimb Bio, Inc. | COM | 251,935 | $453.5K | 0.1% | +69,965+38.4% | Added | History |
| KYTXKyverna Therapeutics, Inc. | COM | 118,758 | $444.2K | 0.1% | −129,893−52.2% | Reduced | History |
| CGENCompugen Ltd | ORD | 177,094 | $271.0K | 0.1% | −50,000−22.0% | Reduced | History |
Options (3)
Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.
Sold out since Q3 2024 (22)
Positions held at the end of Q3 2024 that are gone from this filing.
| Security | Class | Shares in Q3 2024 | Value in Q3 2024 | % of portfolio in Q3 2024 | History |
|---|---|---|---|---|---|
| AAPLApple Inc. | Stock | 60,847 | $14.2M | 2.3% | History |
| SSentinelOne, Inc. | CL A | 276,554 | $6.62M | 1.1% | History |
| PTCTPTC Therapeutics, Inc. | COM | 118,345 | $4.39M | 0.7% | History |
| CRWDCrowdStrike Holdings, Inc. | Stock | 10,862 | $3.05M | 0.5% | History |
| NVDANVIDIA Corp | Stock | 24,355 | $2.96M | 0.5% | History |
| ENLTEnlight Renewable Energy Ltd. | SHS | 151,860 | $2.57M | 0.4% | History |
| GLBEGlobal-E Online Ltd. | SHS | 64,384 | $2.47M | 0.4% | History |
| ASMLASML Holding NV | ADR | 2,840 | $2.37M | 0.4% | History |
| OTLKOutlook Therapeutics, Inc. | Stock | 413,545 | $2.21M | 0.4% | History |
| KLACKLA Corp | COM NEW | 2,775 | $2.15M | 0.4% | History |
| VRDNViridian Therapeutics, Inc. | COM | 86,094 | $1.96M | 0.3% | History |
| ALNYAlnylam Pharmaceuticals, Inc. | COM | 7,000 | $1.93M | 0.3% | History |
| ADIAnalog Devices Inc | Stock | 6,660 | $1.53M | 0.3% | History |
| QCOMQualcomm Inc | Stock | 7,800 | $1.33M | 0.2% | History |
| CAPRCapricor Therapeutics, Inc. | COM NEW | 61,698 | $938.4K | 0.2% | History |
| ADCTADC Therapeutics SA | SHS | 205,036 | $645.9K | 0.1% | History |
| GLUEMonte Rosa Therapeutics, Inc. | COM | 118,103 | $625.9K | 0.1% | History |
| FDMT4D Molecular Therapeutics, Inc. | COM | 48,702 | $526.5K | 0.1% | History |
| TNGXTango Therapeutics, Inc. | COM | 50,000 | $385.0K | 0.1% | History |
| PRMEPrime Medicine, Inc. | COM | 76,456 | $295.9K | <0.1% | History |
| TENXTenax Therapeutics, Inc. | COM NEW | 29,166 | $100.9K | <0.1% | History |
| ARBEArbe Robotics Ltd. | COM | 43,165 | $82.4K | <0.1% | History |