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Livermore
Livermore
ZHEN

Sphera Funds Management Ltd.

SEC CIK
0001496201
Latest filing
Aug 14, 2026

Holdings in Q3 2024

Holdings as of Sep 30, 2024, filed Nov 14, 2024. Long positions only; changes compare share counts with Q2 2024.

Institution overview
Positions
108
−2 vs. Q2 2024
Portfolio value
$611.2M
−$2.34M (−0.4%) vs. Q2 2024
Filed
Nov 14, 2024
SEC
Holdings of Sphera Funds Management Ltd. in Q3 2024
SecurityClassSharesValue% of portfolioShare changeActionHistory
TEVATeva Pharmaceutical Industries LtdSPONSORED ADS2,130,216$38.4M6.3%+1,340,800+169.8%AddedHistory
SNYSanofiSPONSORED ADR409,515$23.6M3.9%−40,000−8.9%ReducedHistory
BBIOBridgeBio Pharma, Inc.COM842,644$21.5M3.5%−67,426−7.4%ReducedHistory
SNDXSyndax Pharmaceuticals IncCOM1,034,846$19.9M3.3%+212,799+25.9%AddedHistory
AMZNAmazon Com IncStock105,607$19.7M3.2%+4,175+4.1%AddedHistory
METAMeta Platforms, Inc.Stock29,316$16.8M2.7%−4,123−12.3%ReducedHistory
SRPTSarepta Therapeutics, Inc.COM125,846$15.7M2.6%+42,187+50.4%AddedHistory
AZNAstraZeneca PLCSPONSORED ADR190,060$14.8M2.4%00.0%UnchangedHistory
MSFTMicrosoft CorpStock33,427$14.4M2.4%+500+1.5%AddedHistory
CLDXCelldex Therapeutics, Inc.COM NEW419,103$14.2M2.3%+109,838+35.5%AddedHistory
AAPLApple Inc.Stock60,847$14.2M2.3%−653−1.1%ReducedHistory
NICENICE Ltd.SPONSORED ADR78,361$13.6M2.2%−3,100−3.8%ReducedHistory
KURAKura Oncology, Inc.COM610,087$11.9M2.0%−739−0.1%ReducedHistory
CYTKCytokinetics IncCOM NEW225,021$11.9M1.9%−159,903−41.5%ReducedHistory
LLYEli Lilly & CoStock13,190$11.7M1.9%00.0%UnchangedHistory
JNJJohnson & JohnsonStock69,831$11.3M1.9%00.0%UnchangedHistory
RAREUltragenyx Pharmaceutical Inc.COM195,349$10.9M1.8%−98,483−33.5%ReducedHistory
NVMINova Ltd.COM51,960$10.8M1.8%+51,960NewHistory
NVONovo Nordisk A SADR78,080$9.30M1.5%00.0%UnchangedHistory
TSEMTower Semiconductor LtdSHS NEW209,441$9.27M1.5%+59,841+40.0%AddedHistory
PRAXPraxis Precision Medicines, Inc.COM NEW152,307$8.76M1.4%−131,117−46.3%ReducedHistory
VKTXViking Therapeutics, Inc.COM133,066$8.42M1.4%+133,066NewHistory
HELPCybin Inc.COM NEW933,225$8.30M1.4%+933,225NewHistory
IMTXImmatics N.V.SHS721,111$8.23M1.3%−10,000−1.4%ReducedHistory
PHVSPharvaris N.V.COM439,292$8.14M1.3%+36,027+8.9%AddedHistory
CATXPerspective Therapeutics, Inc.COM NEW589,295$7.87M1.3%−197,614−25.1%ReducedHistory
CHKPCheck Point Software Technologies LtdORD40,215$7.75M1.3%+40,215NewHistory
ABBVAbbVie Inc.Stock38,000$7.50M1.2%00.0%UnchangedHistory
MRUSMerus N.V.COM147,633$7.38M1.2%00.0%UnchangedHistory
ENPHEnphase Energy, Inc.Stock64,224$7.26M1.2%+7,432+13.1%AddedHistory
MRKMerck & Co., Inc.Stock59,600$6.77M1.1%00.0%UnchangedHistory
BHVNBiohaven Ltd.COM133,323$6.66M1.1%+133,323NewHistory
SSentinelOne, Inc.CL A276,554$6.62M1.1%−7,250−2.6%ReducedHistory
MRVLMarvell Technology, Inc.COM87,611$6.32M1.0%+67,611+338.1%AddedHistory
INZYInozyme Pharma, Inc.COM1,191,140$6.23M1.0%−271,584−18.6%ReducedHistory
APLSApellis Pharmaceuticals, Inc.COM215,873$6.23M1.0%+215,873NewHistory
SKYESkye Bioscience, Inc.COM NEW1,563,522$6.11M1.0%+265,210+20.4%AddedHistory
NTLAIntellia Therapeutics, Inc.COM291,080$5.98M1.0%+151,661+108.8%AddedHistory
RZLTRezolute, Inc.COM NEW1,196,938$5.81M0.9%−511,061−29.9%ReducedHistory
NVSNovartis AGADR50,000$5.75M0.9%00.0%UnchangedHistory
WIXWix.com Ltd.SHS34,253$5.73M0.9%+9,076+36.0%AddedHistory
VIGLVigil Neuroscience, Inc.COM1,647,604$5.60M0.9%−44,562−2.6%ReducedHistory
Ormat Technologies, Inc.686688AC6DEBT 2.500% 7/15,037,000$5.26M0.9%+5,037,000New–
DAWNDay One Biopharmaceuticals, Inc.Stock347,627$4.84M0.8%00.0%UnchangedHistory
BIIBBiogen Inc.COM24,455$4.74M0.8%−22,957−48.4%ReducedHistory
PTCTPTC Therapeutics, Inc.COM118,345$4.39M0.7%+24,027+25.5%AddedHistory
RCKTRocket Pharmaceuticals, Inc.COM231,792$4.28M0.7%+24,859+12.0%AddedHistory
GSKGSK plcADR100,000$4.09M0.7%00.0%UnchangedHistory
ETNB89bio, Inc.COM536,547$3.97M0.6%+10,000+1.9%AddedHistory
ACADAcadia Pharmaceuticals IncCOM252,539$3.88M0.6%−75,000−22.9%ReducedHistory
JSPRJasper Therapeutics, Inc.COM NEW189,270$3.56M0.6%−264,957−58.3%ReducedHistory
CRGXCARGO Therapeutics, Inc.COM190,506$3.51M0.6%+35,000+22.5%AddedHistory
FROGJFrog LtdStock120,381$3.50M0.6%+2,500+2.1%AddedHistory
PLRXPliant Therapeutics, Inc.COM297,362$3.33M0.5%+38,808+15.0%AddedHistory
MLYSMineralys Therapeutics, Inc.COM272,472$3.30M0.5%−170,280−38.5%ReducedHistory
ELDNEledon Pharmaceuticals, Inc.COM1,297,321$3.23M0.5%+3000.0%AddedHistory
CGEMCullinan Therapeutics, Inc.COM185,871$3.11M0.5%+185,871NewHistory
CRWDCrowdStrike Holdings, Inc.Stock10,862$3.05M0.5%+10,862NewHistory
ZURAZura Bio LtdCLASS A ORD SHS738,718$3.00M0.5%+738,718NewHistory
NVDANVIDIA CorpStock24,355$2.96M0.5%+4,355+21.8%AddedHistory
AVGOBroadcom Inc.Stock16,880$2.91M0.5%−176,720−91.3%ReducedConverted for a 10-for-1 splitHistory
CAMTCamtek LtdORD36,287$2.90M0.5%+34,347+1,770.5%AddedHistory
ALECAlector, Inc.COM620,000$2.89M0.5%+10,000+1.6%AddedHistory
LRMRLarimar Therapeutics, Inc.COM414,478$2.71M0.4%+102,009+32.6%AddedHistory
APLTApplied Therapeutics, Inc.COM311,572$2.65M0.4%−362,696−53.8%ReducedHistory
PFEPfizer IncStock90,000$2.60M0.4%00.0%UnchangedHistory
ENLTEnlight Renewable Energy Ltd.SHS151,860$2.57M0.4%−17,420−10.3%ReducedHistory
IONSIonis Pharmaceuticals IncCOM63,821$2.56M0.4%−76,417−54.5%ReducedHistory
GLBEGlobal-E Online Ltd.SHS64,384$2.47M0.4%−2,500−3.7%ReducedHistory
VTGNVistagen Therapeutics, Inc.COM808,550$2.43M0.4%00.0%UnchangedHistory
PMNProMIS Neurosciences Inc.COM1,929,297$2.41M0.4%+115,084+6.3%AddedHistory
SVRASavara IncCOM563,107$2.39M0.4%−399,580−41.5%ReducedHistory
ASMLASML Holding NVADR2,840$2.37M0.4%−7,061−71.3%ReducedHistory
OTLKOutlook Therapeutics, Inc.Stock413,545$2.21M0.4%−157,883−27.6%ReducedHistory
VTYXVentyx Biosciences, Inc.COM1,012,749$2.21M0.4%00.0%UnchangedHistory
KLACKLA CorpCOM NEW2,775$2.15M0.4%−525−15.9%ReducedHistory
SHL Telemedicine Ltd78423T200ADS632,456$2.13M0.3%00.0%Unchanged–
DYNDyne Therapeutics, Inc.COM56,504$2.03M0.3%+56,504NewHistory
VRDNViridian Therapeutics, Inc.COM86,094$1.96M0.3%+86,094NewHistory
NTRNutrien Ltd.COM40,730$1.96M0.3%00.0%UnchangedHistory
ALNYAlnylam Pharmaceuticals, Inc.COM7,000$1.93M0.3%+7,000NewHistory
CMMBChemomab Therapeutics Ltd.SPONSORED ADS1,214,575$1.91M0.3%+1,214,575NewHistory
PERIPerion Network Ltd.SHS NEW234,609$1.85M0.3%00.0%UnchangedHistory
WDAYWorkday, Inc.CL A7,500$1.83M0.3%+7,500NewHistory
KZRKezar Life Sciences, Inc.COM205,168$1.59M0.3%−1,846,508−90.0%ReducedHistory
ADIAnalog Devices IncStock6,660$1.53M0.3%−6,340−48.8%ReducedHistory
ATXSAstria Therapeutics, Inc.COM136,582$1.50M0.2%−26,260−16.1%ReducedHistory
SRRKScholar Rock Holding CorpCOM166,866$1.34M0.2%+166,866NewHistory
ALMSAlumis Inc.COM125,000$1.33M0.2%00.0%UnchangedHistory
HOWLWerewolf Therapeutics, Inc.COM626,810$1.33M0.2%00.0%UnchangedHistory
QCOMQualcomm IncStock7,800$1.33M0.2%−11,025−58.6%ReducedHistory
ORICOric Pharmaceuticals, Inc.COM128,396$1.32M0.2%+128,396NewHistory
KYTXKyverna Therapeutics, Inc.COM248,651$1.22M0.2%+12,622+5.3%AddedHistory
CAPRCapricor Therapeutics, Inc.COM NEW61,698$938.4K0.2%+61,698NewHistory
CLYMClimb Bio, Inc.COM181,970$926.2K0.2%−33,209−15.4%ReducedHistory
APREAprea Therapeutics, Inc.COM NEW270,000$742.5K0.1%00.0%UnchangedHistory
VIRVir Biotechnology, Inc.COM93,329$699.0K0.1%−68,722−42.4%ReducedHistory
ELEVElevation Acquisition Group Inc.COM1,079,762$647.7K0.1%+749,762+227.2%AddedHistory
ADCTADC Therapeutics SASHS205,036$645.9K0.1%−480,511−70.1%ReducedHistory
GLUEMonte Rosa Therapeutics, Inc.COM118,103$625.9K0.1%−256,897−68.5%ReducedHistory

Options (6)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Sphera Funds Management Ltd. in Q3 2024
SecurityClassPutsCalls
NICENICE Ltd.SPONSORED ADR–$5.57M
PRAXPraxis Precision Medicines, Inc.COM NEW$2.99M$2.30M
CYTKCytokinetics IncCOM NEW–$2.64M
TVTXTravere Therapeutics, Inc.COM–$2.39M
JSPRJasper Therapeutics, Inc.COM NEW–$1.15M
SRPTSarepta Therapeutics, Inc.COM–$124.9K

Sold out since Q2 2024 (22)

Positions held at the end of Q2 2024 that are gone from this filing.

Positions of Sphera Funds Management Ltd. sold out since Q2 2024
SecurityClassShares in Q2 2024Value in Q2 2024% of portfolio in Q2 2024History
CRMSalesforce, Inc.Stock33,600$8.64M1.4%History
Cybin Ord23256X100COM25,581,395$6.93M1.1%–
PANWPalo Alto Networks IncStock18,000$6.10M1.0%History
AMATApplied Materials IncStock24,604$5.81M0.9%History
MUMicron Technology IncStock37,000$4.87M0.8%History
CPRXCatalyst Pharmaceuticals, Inc.COM288,000$4.46M0.7%History
LRCXLam Research CorpCOM3,700$3.94M0.6%History
AKROAkero Therapeutics, Inc.COM141,620$3.32M0.5%History
SWTXSpringWorks Therapeutics, Inc.COM70,269$2.65M0.4%History
IRONDisc Medicine, Inc.COM58,044$2.62M0.4%History
TBLATaboola.com Ltd.ORD SHS667,384$2.30M0.4%History
LHXL3HARRIS Technologies, Inc.Stock10,000$2.25M0.4%History
UPWKUpwork, IncCOM117,000$1.26M0.2%History
ARWRArrowhead Pharmaceuticals, Inc.COM48,175$1.25M0.2%History
INSMINSMED IncCOM PAR $.0116,589$1.11M0.2%History
TSMTaiwan Semiconductor Manufacturing Co LtdADR5,650$982.0K0.2%History
VRNSVaronis Systems IncCOM16,000$767.5K0.1%History
RNACCartesian Therapeutics, Inc.COM NEW25,070$677.1K0.1%History
ARGXArgenx SESPONSORED ADR1,556$669.1K0.1%History
ICLICL Group Ltd.SHS107,238$459.0K0.1%History
GOSSGossamer Bio, Inc.COM222,134$200.1K<0.1%History
AMLXAmylyx Pharmaceuticals, Inc.COM36,050$68.5K<0.1%History