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Sphera Funds Management Ltd.

SEC CIK
0001496201
Latest filing
Aug 14, 2026

Holdings in Q2 2024

Holdings as of Jun 30, 2024, filed Aug 14, 2024. Long positions only; changes compare share counts with Q1 2024.

Institution overview
Positions
110
+17 vs. Q1 2024
Portfolio value
$613.6M
−$3.99M (−0.6%) vs. Q1 2024
Filed
Aug 14, 2024
SEC
Holdings of Sphera Funds Management Ltd. in Q2 2024
SecurityClassSharesValue% of portfolioShare changeActionHistory
BBIOBridgeBio Pharma, Inc.COM910,070$23.1M3.8%+324,114+55.3%AddedHistory
SNYSanofiSPONSORED ADR449,515$21.8M3.6%−50,000−10.0%ReducedHistory
CYTKCytokinetics IncCOM NEW384,924$20.9M3.4%+103,253+36.7%AddedHistory
AMZNAmazon Com IncStock101,432$19.6M3.2%+47,000+86.3%AddedHistory
SNDXSyndax Pharmaceuticals IncCOM822,047$16.9M2.8%+9,083+1.1%AddedHistory
METAMeta Platforms, Inc.Stock33,439$16.9M2.7%+8,000+31.4%AddedHistory
AZNAstraZeneca PLCSPONSORED ADR190,060$14.8M2.4%00.0%UnchangedHistory
MSFTMicrosoft CorpStock32,927$14.7M2.4%+5,379+19.5%AddedHistory
NICENICE Ltd.SPONSORED ADR81,461$14.0M2.3%−4,420−5.1%ReducedHistory
SRPTSarepta Therapeutics, Inc.COM83,659$13.2M2.2%+28,045+50.4%AddedHistory
AAPLApple Inc.Stock61,500$13.0M2.1%+44,000+251.4%AddedHistory
TEVATeva Pharmaceutical Industries LtdSPONSORED ADS789,416$12.8M2.1%−1,100,284−58.2%ReducedHistory
KURAKura Oncology, Inc.COM610,826$12.6M2.0%00.0%UnchangedHistory
RAREUltragenyx Pharmaceutical Inc.COM293,832$12.1M2.0%+55,288+23.2%AddedHistory
LLYEli Lilly & CoStock13,190$11.9M1.9%−1,000−7.0%ReducedHistory
PRAXPraxis Precision Medicines, Inc.COM NEW283,424$11.7M1.9%+106,285+60.0%AddedHistory
CLDXCelldex Therapeutics, Inc.COM NEW309,265$11.4M1.9%+32,269+11.6%AddedHistory
NVONovo Nordisk A SADR78,080$11.1M1.8%−5,000−6.0%ReducedHistory
BIIBBiogen Inc.COM47,412$11.0M1.8%−23,234−32.9%ReducedHistory
SKYESkye Bioscience, Inc.COM NEW1,298,312$10.4M1.7%+1,298,312NewHistory
JSPRJasper Therapeutics, Inc.COM NEW454,227$10.3M1.7%−51,015−10.1%ReducedHistory
JNJJohnson & JohnsonStock69,831$10.2M1.7%−10,000−12.5%ReducedHistory
ASMLASML Holding NVADR9,901$10.1M1.7%+9,901NewHistory
MRUSMerus N.V.COM147,633$8.74M1.4%−1,700−1.1%ReducedHistory
CRMSalesforce, Inc.Stock33,600$8.64M1.4%+33,600NewHistory
IMTXImmatics N.V.SHS731,111$8.50M1.4%+65,000+9.8%AddedHistory
CATXPerspective Therapeutics, Inc.COM NEW786,909$7.85M1.3%+786,909NewHistory
PHVSPharvaris N.V.COM403,265$7.58M1.2%+10,388+2.6%AddedHistory
MRKMerck & Co., Inc.Stock59,600$7.38M1.2%−44,000−42.5%ReducedHistory
RZLTRezolute, Inc.COM NEW1,707,999$7.34M1.2%+711,289+71.4%AddedHistory
Cybin Ord23256X100COM25,581,395$6.93M1.1%00.0%Unchanged–
VIGLVigil Neuroscience, Inc.COM1,692,166$6.77M1.1%−38,248−2.2%ReducedHistory
IONSIonis Pharmaceuticals IncCOM140,238$6.68M1.1%+140,238NewHistory
INZYInozyme Pharma, Inc.COM1,462,724$6.52M1.1%+89,817+6.5%AddedHistory
ABBVAbbVie Inc.Stock38,000$6.52M1.1%00.0%UnchangedHistory
PANWPalo Alto Networks IncStock18,000$6.10M1.0%+18,000NewHistory
SSentinelOne, Inc.CL A283,804$5.97M1.0%−267,014−48.5%ReducedHistory
TSEMTower Semiconductor LtdSHS NEW149,600$5.88M1.0%−30,000−16.7%ReducedHistory
AMATApplied Materials IncStock24,604$5.81M0.9%−7,396−23.1%ReducedHistory
ENPHEnphase Energy, Inc.Stock56,792$5.66M0.9%+9,609+20.4%AddedHistory
NVSNovartis AGADR50,000$5.32M0.9%00.0%UnchangedHistory
ACADAcadia Pharmaceuticals IncCOM327,539$5.32M0.9%+202,539+162.0%AddedHistory
MLYSMineralys Therapeutics, Inc.COM442,752$5.18M0.8%−216,051−32.8%ReducedHistory
FDMT4D Molecular Therapeutics, Inc.COM242,526$5.09M0.8%+80,365+49.6%AddedHistory
MUMicron Technology IncStock37,000$4.87M0.8%+37,000NewHistory
DAWNDay One Biopharmaceuticals, Inc.Stock347,627$4.79M0.8%−145,000−29.4%ReducedHistory
CPRXCatalyst Pharmaceuticals, Inc.COM288,000$4.46M0.7%00.0%UnchangedHistory
RCKTRocket Pharmaceuticals, Inc.COM206,933$4.46M0.7%+23,211+12.6%AddedHistory
FROGJFrog LtdStock117,881$4.43M0.7%−106,500−47.5%ReducedHistory
ETNB89bio, Inc.COM526,547$4.22M0.7%+10,665+2.1%AddedHistory
OTLKOutlook Therapeutics, Inc.Stock571,428$4.22M0.7%−10.0%ReducedHistory
WIXWix.com Ltd.SHS25,177$4.00M0.7%−27,700−52.4%ReducedHistory
LRCXLam Research CorpCOM3,700$3.94M0.6%+3,700NewHistory
SVRASavara IncCOM962,687$3.88M0.6%+962,687NewHistory
GSKGSK plcADR100,000$3.85M0.6%00.0%UnchangedHistory
QCOMQualcomm IncStock18,825$3.75M0.6%+3,825+25.5%AddedHistory
ELDNEledon Pharmaceuticals, Inc.COM1,297,021$3.42M0.6%+1,297,021NewHistory
AKROAkero Therapeutics, Inc.COM141,620$3.32M0.5%−18,825−11.7%ReducedHistory
SHL Telemedicine Ltd78423T200ADS632,456$3.22M0.5%00.0%Unchanged–
APLTApplied Therapeutics, Inc.COM674,268$3.15M0.5%+55,239+8.9%AddedHistory
NTLAIntellia Therapeutics, Inc.COM139,419$3.12M0.5%+139,419NewHistory
AVGOBroadcom Inc.Stock19,360$3.11M0.5%+18,359+1,834.1%AddedHistory
ADIAnalog Devices IncStock13,000$2.97M0.5%+13,000NewHistory
PTCTPTC Therapeutics, Inc.COM94,318$2.88M0.5%+94,318NewHistory
VTGNVistagen Therapeutics, Inc.COM808,550$2.81M0.5%00.0%UnchangedHistory
PLRXPliant Therapeutics, Inc.COM258,554$2.78M0.5%00.0%UnchangedHistory
ALECAlector, Inc.COM610,000$2.77M0.5%+50,000+8.9%AddedHistory
ENLTEnlight Renewable Energy Ltd.SHS169,280$2.74M0.4%00.0%UnchangedHistory
PMNProMIS Neurosciences Inc.COM1,814,213$2.72M0.4%−19,834−1.1%ReducedHistory
KLACKLA CorpCOM NEW3,300$2.72M0.4%+3,300NewHistory
SWTXSpringWorks Therapeutics, Inc.COM70,269$2.65M0.4%00.0%UnchangedHistory
IRONDisc Medicine, Inc.COM58,044$2.62M0.4%+9,158+18.7%AddedHistory
CRGXCARGO Therapeutics, Inc.COM155,506$2.55M0.4%+80,506+107.3%AddedHistory
PFEPfizer IncStock90,000$2.52M0.4%00.0%UnchangedHistory
NVDANVIDIA CorpStock20,000$2.47M0.4%+20,000NewHistory
GLBEGlobal-E Online Ltd.SHS66,884$2.43M0.4%−141,900−68.0%ReducedHistory
VTYXVentyx Biosciences, Inc.COM1,012,749$2.34M0.4%+20,000+2.0%AddedHistory
TBLATaboola.com Ltd.ORD SHS667,384$2.30M0.4%−523,686−44.0%ReducedHistory
LRMRLarimar Therapeutics, Inc.COM312,469$2.27M0.4%+312,469NewHistory
LHXL3HARRIS Technologies, Inc.Stock10,000$2.25M0.4%+10,000NewHistory
ADCTADC Therapeutics SASHS685,547$2.17M0.4%+685,547NewHistory
NTRNutrien Ltd.COM40,730$2.07M0.3%+5,000+14.0%AddedHistory
PERIPerion Network Ltd.SHS NEW234,609$1.96M0.3%+234,609NewHistory
KYTXKyverna Therapeutics, Inc.COM236,029$1.77M0.3%+236,029NewHistory
ALMSAlumis Inc.COM125,000$1.66M0.3%+125,000NewHistory
CLYMClimb Bio, Inc.COM215,179$1.53M0.2%+215,179NewHistory
HOWLWerewolf Therapeutics, Inc.COM626,810$1.53M0.2%00.0%UnchangedHistory
ATXSAstria Therapeutics, Inc.COM162,842$1.48M0.2%+50,000+44.3%AddedHistory
VIRVir Biotechnology, Inc.COM162,051$1.44M0.2%+162,051NewHistory
GLUEMonte Rosa Therapeutics, Inc.COM375,000$1.40M0.2%+375,000NewHistory
MRVLMarvell Technology, Inc.COM20,000$1.40M0.2%+20,000NewHistory
UPWKUpwork, IncCOM117,000$1.26M0.2%00.0%UnchangedHistory
ARWRArrowhead Pharmaceuticals, Inc.COM48,175$1.25M0.2%+48,175NewHistory
CGENCompugen LtdORD739,239$1.24M0.2%−30,000−3.9%ReducedHistory
KZRKezar Life Sciences, Inc.COM2,051,676$1.23M0.2%00.0%UnchangedHistory
INSMINSMED IncCOM PAR $.0116,589$1.11M0.2%+16,589NewHistory
APREAprea Therapeutics, Inc.COM NEW270,000$1.10M0.2%00.0%UnchangedHistory
TSMTaiwan Semiconductor Manufacturing Co LtdADR5,650$982.0K0.2%+5,650NewHistory
ELEVElevation Acquisition Group Inc.COM330,000$891.0K0.1%−100,000−23.3%ReducedHistory
VRNSVaronis Systems IncCOM16,000$767.5K0.1%−4,000−20.0%ReducedHistory

Options (8)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Sphera Funds Management Ltd. in Q2 2024
SecurityClassPutsCalls
TEVATeva Pharmaceutical Industries LtdSPONSORED ADS–$53.1M
VanEck Semiconductor ETF92189F676ETF$39.1M–
Invesco QQQ Trust Series I46090E103ETF–$11.0M
NICENICE Ltd.SPONSORED ADR–$5.52M
BBIOBridgeBio Pharma, Inc.COM–$5.18M
PRAXPraxis Precision Medicines, Inc.COM NEW–$3.10M
SRPTSarepta Therapeutics, Inc.COM–$2.37M
FULCFulcrum Therapeutics, Inc.COM$365.8K–

Sold out since Q1 2024 (13)

Positions held at the end of Q1 2024 that are gone from this filing.

Positions of Sphera Funds Management Ltd. sold out since Q1 2024
SecurityClassShares in Q1 2024Value in Q1 2024% of portfolio in Q1 2024History
CATXPerspective Therapeutics, Inc.COM12,443,621$14.8M2.4%History
FUSNFusion Pharmaceuticals Inc.COM449,041$9.57M1.6%History
NVMINova Ltd.COM35,106$6.23M1.0%History
INCYIncyte CorpCOM89,556$5.10M0.8%History
SEDGSolaredge Technologies, Inc.COM40,175$2.85M0.5%History
ESTCElastic N.V.ORD SHS20,000$2.00M0.3%History
AMDAdvanced Micro Devices IncStock11,000$1.99M0.3%History
ALPNAlpine Immune Sciences, Inc.COM44,841$1.78M0.3%History
FIVNFive9, Inc.COM27,500$1.71M0.3%History
CRBPCorbus Pharmaceuticals Holdings, Inc.COM NEW35,000$1.37M0.2%History
GERNGeron CorpCOM384,356$1.27M0.2%History
RNACCartesian Therapeutics, Inc.COM25,071$488.9K0.1%History
ANROAlto Neuroscience, Inc.COM SHS30,500$468.2K0.1%History