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Artal Group S.A.

SEC CIK
0001053906
Latest filing
Aug 13, 2026

Holdings in Q2 2022

Holdings as of Jun 30, 2022, filed Aug 11, 2022. Long positions only; changes compare share counts with Q1 2022.

Institution overview
Positions
132
−3 vs. Q1 2022
Portfolio value
$1.80B
−$566.9M (−24.0%) vs. Q1 2022
Filed
Aug 11, 2022
SEC
Holdings of Artal Group S.A. in Q2 2022
SecurityClassSharesValue% of portfolioShare changeActionHistory
ARGXArgenx SESPONSORED ADR400,000$151.6M8.4%−187,500−31.9%ReducedHistory
LXRXLexicon Pharmaceuticals, Inc.COM NEW71,178,364$132.4M7.4%00.0%UnchangedHistory
ONCBeOne Medicines Ltd.ADR650,000$105.2M5.8%−15,000−2.3%ReducedHistory
WWWW International, Inc.COM14,818,300$94.7M5.3%00.0%UnchangedHistory
SGENSeagen Inc.COM525,000$92.9M5.2%−125,000−19.2%ReducedHistory
ALNYAlnylam Pharmaceuticals, Inc.COM600,000$87.5M4.9%−50,000−7.7%ReducedHistory
MRTXMirati Therapeutics, Inc.COM1,100,000$73.8M4.1%−250,000−18.5%ReducedHistory
Bellus Health Inc New07987C204COM NEW7,000,000$64.7M3.6%−1,500,000−17.6%Reduced–
FATEFate Therapeutics IncCOM2,600,000$64.4M3.6%+600,000+30.0%AddedHistory
CYTKCytokinetics IncCOM NEW1,275,000$50.1M2.8%+275,000+27.5%AddedHistory
SRRKScholar Rock Holding CorpCOM8,750,034$48.0M2.7%+6,300,034+257.1%AddedHistory
FOLDAmicus Therapeutics, Inc.COM4,000,000$43.0M2.4%00.0%UnchangedHistory
SEERSeer, Inc.COM CL A4,750,000$42.5M2.4%00.0%UnchangedHistory
CERECerevel Therapeutics Holdings, Inc.COM1,500,000$39.7M2.2%00.0%UnchangedHistory
IGMSIGM Biosciences, Inc.COM2,000,000$36.1M2.0%00.0%UnchangedHistory
MORFMorphic Holding, Inc.COM1,650,000$35.8M2.0%00.0%UnchangedHistory
KRYSKrystal Biotech, Inc.COM500,000$32.8M1.8%00.0%UnchangedHistory
FHTXFoghorn Therapeutics Inc.COM1,720,720$23.4M1.3%00.0%UnchangedHistory
SWTXSpringWorks Therapeutics, Inc.COM900,000$22.2M1.2%+50,000+5.9%AddedHistory
GOSSGossamer Bio, Inc.COM2,358,968$19.7M1.1%00.0%UnchangedHistory
KYMRKymera Therapeutics, Inc.COM1,000,000$19.7M1.1%00.0%UnchangedHistory
KURAKura Oncology, Inc.COM1,050,000$19.2M1.1%00.0%UnchangedHistory
EQRXEQRx, Inc.COM4,000,000$18.8M1.0%00.0%UnchangedHistory
SDGRSchrodinger, Inc.COM700,000$18.5M1.0%00.0%UnchangedHistory
GBIOGeneration Bio Co.COM2,814,191$18.5M1.0%00.0%UnchangedHistory
ERASErasca, Inc.COM3,172,221$17.7M1.0%00.0%UnchangedHistory
DNLIDenali Therapeutics Inc.COM600,000$17.7M1.0%00.0%UnchangedHistory
REPLReplimune Group, Inc.COM900,000$15.7M0.9%00.0%UnchangedHistory
SAGESage Therapeutics, Inc.COM450,000$14.5M0.8%−300,000−40.0%ReducedHistory
NTLAIntellia Therapeutics, Inc.COM275,000$14.2M0.8%00.0%UnchangedHistory
EVOEvotec SESPONSORED ADS1,149,425$13.8M0.8%00.0%UnchangedHistory
RLAYRelay Therapeutics, Inc.COM700,000$11.7M0.7%00.0%UnchangedHistory
MRSNMersana Therapeutics, Inc.COM2,200,000$10.2M0.6%00.0%UnchangedHistory
AUPHAurinia Pharmaceuticals Inc.COM1,000,000$10.1M0.6%00.0%UnchangedHistory
RPTXRepare Therapeutics Inc.COM700,000$9.79M0.5%00.0%UnchangedHistory
WVEWave Life Sciences, Inc.SHS3,000,000$9.75M0.5%+2,000,000+200.0%AddedHistory
NBPNovaBridge BiosciencesSPONSORED ADS850,000$9.61M0.5%00.0%UnchangedHistory
TRMLTourmaline Bio, Inc.COM2,064,262$9.31M0.5%00.0%UnchangedHistory
KLRSKalaris Therapeutics, Inc.COM2,323,371$9.06M0.5%00.0%UnchangedHistory
OMGAOmega Therapeutics, Inc.COMMON STOCK2,273,530$8.64M0.5%00.0%UnchangedHistory
ITOSiTeos Therapeutics, Inc.COM400,000$8.24M0.5%00.0%UnchangedHistory
ATRAAtara Biotherapeutics, Inc.COM1,000,000$7.79M0.4%00.0%UnchangedHistory
Omega Alpha SpacG6749V107CL A750,000$7.39M0.4%00.0%Unchanged–
IMAImageneBio, Inc.COM1,549,513$6.86M0.4%00.0%UnchangedHistory
RNACCartesian Therapeutics, Inc.COM4,883,200$6.40M0.4%+883,200+22.1%AddedHistory
VERVVerve Therapeutics, Inc.COM400,000$6.11M0.3%00.0%UnchangedHistory
YMABY-mAbs Therapeutics, Inc.COM400,000$6.05M0.3%00.0%UnchangedHistory
Exscientia PLC30223G102ADS550,000$5.99M0.3%00.0%Unchanged–
AGENAgenus IncCOM NEW3,000,000$5.82M0.3%−2,500,000−45.5%ReducedHistory
AMAMAmbrx Biopharma Cayman, Inc.SPONSORED ADS2,152,291$5.70M0.3%00.0%UnchangedHistory
Achilles Therapeutics PLC00449L102SPONSORED ADS2,255,375$5.68M0.3%00.0%Unchanged–
KRONKronos Bio, Inc.COM1,542,954$5.62M0.3%00.0%UnchangedHistory
DSGNDesign Therapeutics, Inc.COM400,000$5.60M0.3%00.0%UnchangedHistory
OVIDOvid Therapeutics Inc.COM2,500,000$5.38M0.3%00.0%UnchangedHistory
OTLYOatly Group ABSPONSORED ADS1,500,000$5.19M0.3%00.0%UnchangedHistory
SQZSQZ Biotechnologies CoCOM1,606,309$5.11M0.3%00.0%UnchangedHistory
ALPNAlpine Immune Sciences, Inc.COM593,030$5.05M0.3%00.0%UnchangedHistory
MRNSMarinus Pharmaceuticals, Inc.COM NEW1,000,000$4.84M0.3%00.0%UnchangedHistory
CFRXCONTRAFECT CorpCOM NEW1,500,000$4.61M0.3%00.0%UnchangedHistory
CYPHCypherpunk Technologies Inc.COM4,000,000$4.60M0.3%00.0%UnchangedHistory
LYELLyell Immunopharma, Inc.COM700,000$4.56M0.3%00.0%UnchangedHistory
BDTXBlack Diamond Therapeutics, Inc.COM1,646,517$4.05M0.2%00.0%UnchangedHistory
ALXOAlx Oncology Holdings IncCOM500,000$4.04M0.2%00.0%UnchangedHistory
TSHATaysha Gene Therapies, Inc.COM SHS1,040,882$3.87M0.2%00.0%UnchangedHistory
SYRSSyros Pharmaceuticals, Inc.COM4,000,000$3.85M0.2%+500,000+14.3%AddedHistory
SESea LtdSPONSORD ADS57,500$3.84M0.2%00.0%UnchangedHistory
NBTXNanobiotix S.A.SPONSORED ADS1,000,000$3.80M0.2%00.0%UnchangedHistory
PFTAPerception Capital Corp. IIICLASS A ORD SHS380,000$3.71M0.2%00.0%UnchangedHistory
RXRXRecursion Pharmaceuticals, Inc.CL A450,000$3.66M0.2%00.0%UnchangedHistory
Avidity Biosciences, Inc.05370A108COM250,000$3.63M0.2%00.0%Unchanged–
ACIUAC Immune SASHS1,000,000$3.61M0.2%00.0%UnchangedHistory
DYNDyne Therapeutics, Inc.COM525,000$3.61M0.2%00.0%UnchangedHistory
ADVMAdverum Biotechnologies, Inc.COM3,000,000$3.60M0.2%00.0%UnchangedHistory
APTXAptinyx Inc.COM6,116,493$3.41M0.2%00.0%UnchangedHistory
STOKStoke Therapeutics, Inc.COM250,000$3.30M0.2%00.0%UnchangedHistory
IVVDInvivyd, Inc.COM1,000,000$3.28M0.2%00.0%UnchangedHistory
CGEMCullinan Therapeutics, Inc.COM250,000$3.21M0.2%00.0%UnchangedHistory
RUBYRubius Therapeutics, Inc.COM3,701,580$3.15M0.2%00.0%UnchangedHistory
HOOKHOOKIPA Pharma Inc.COM1,849,616$3.02M0.2%00.0%UnchangedHistory
PRAXPraxis Precision Medicines, Inc.COM1,200,000$2.94M0.2%00.0%UnchangedHistory
VIGLVigil Neuroscience, Inc.COM1,121,191$2.89M0.2%00.0%UnchangedHistory
MIRMirion Technologies, Inc.COM CL A500,000$2.88M0.2%00.0%UnchangedHistory
VORVor Biopharma Inc.COM550,000$2.73M0.2%00.0%UnchangedHistory
CINCCinCor Pharma, Inc.COM137,010$2.58M0.1%+137,010NewHistory
SANASana Biotechnology, Inc.COM400,000$2.57M0.1%00.0%UnchangedHistory
IMUXImmunic, Inc.COM700,000$2.43M0.1%00.0%UnchangedHistory
ZYMEZymeworks Inc.COM450,000$2.38M0.1%00.0%UnchangedHistory
BBIOBridgeBio Pharma, Inc.COM250,000$2.27M0.1%00.0%UnchangedHistory
TCRRTCR2 Therapeutics Inc.COM750,000$2.17M0.1%00.0%UnchangedHistory
TILInstil Bio, Inc.COM450,000$2.08M0.1%00.0%UnchangedHistory
SNTISenti Biosciences Holdings, Inc.COM1,055,555$2.07M0.1%+1,055,555NewHistory
ADAGAdagene Inc.ADS1,000,000$2.07M0.1%00.0%UnchangedHistory
IMMPIMMUTEP LtdSPONSORED ADS1,000,000$2.03M0.1%00.0%UnchangedHistory
YI111, Inc.ADS966,349$1.99M0.1%00.0%UnchangedHistory
NEXINexImmune, Inc.COM1,200,000$1.93M0.1%00.0%UnchangedHistory
LENZLENZ Therapeutics, Inc.COM700,000$1.93M0.1%00.0%UnchangedHistory
HARPHarpoon Therapeutics, Inc.COM1,000,000$1.91M0.1%00.0%UnchangedHistory
FUSNFusion Pharmaceuticals Inc.COM750,000$1.87M0.1%00.0%UnchangedHistory
SLDBSolid Biosciences Inc.COM3,000,000$1.85M0.1%00.0%UnchangedHistory
GRTSGritstone bio, Inc.COM750,000$1.81M0.1%00.0%UnchangedHistory

Options (3)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Artal Group S.A. in Q2 2022
SecurityClassPutsCalls
CCitigroup IncStock–$46.0M
Direxion Shs ETF Tr25490K323SP BIOTCH BL NEW–$27.0M
IGMSIGM Biosciences, Inc.COM–$902.0K

Sold out since Q1 2022 (8)

Positions held at the end of Q1 2022 that are gone from this filing.

Positions of Artal Group S.A. sold out since Q1 2022
SecurityClassShares in Q1 2022Value in Q1 2022% of portfolio in Q1 2022History
PTGXProtagonist Therapeutics, IncCOM800,100$18.9M0.8%History
APLSApellis Pharmaceuticals, Inc.COM200,000$10.2M0.4%History
FMTXForma Therapeutics Holdings, Inc.SHS1,000,000$9.30M0.4%History
TGTXTG Therapeutics, Inc.COM800,000$7.61M0.3%History
IMCRImmunocore Holdings plcADS200,000$5.98M0.3%History
Dynamics Special Purpose Cor268010105CLASS A COM500,000$4.93M0.2%–
XPXP Inc.CL A35,000$1.05M<0.1%History
DNAGinkgo Bioworks Holdings, Inc.CL A SHS50,000$202.0K<0.1%History