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Artal Group S.A.

SEC CIK
0001053906
Latest filing
Aug 13, 2026

Holdings in Q1 2022

Holdings as of Mar 31, 2022, filed May 12, 2022. Long positions only; changes compare share counts with Q4 2021.

Institution overview
Positions
135
−9 vs. Q4 2021
Portfolio value
$2.37B
−$1.04B (−30.5%) vs. Q4 2021
Filed
May 12, 2022
SEC
Holdings of Artal Group S.A. in Q1 2022
SecurityClassSharesValue% of portfolioShare changeActionHistory
ARGXArgenx SESPONSORED ADR587,500$185.2M7.8%+87,500+17.5%AddedHistory
WWWW International, Inc.COM14,818,300$151.6M6.4%00.0%UnchangedHistory
LXRXLexicon Pharmaceuticals, Inc.COM NEW71,178,364$148.8M6.3%00.0%UnchangedHistory
ONCBeOne Medicines Ltd.ADR665,000$125.4M5.3%−10,000−1.5%ReducedHistory
MRTXMirati Therapeutics, Inc.COM1,350,000$111.0M4.7%−50,000−3.6%ReducedHistory
ALNYAlnylam Pharmaceuticals, Inc.COM650,000$106.1M4.5%00.0%UnchangedHistory
SGENSeagen Inc.COM650,000$93.6M4.0%+150,000+30.0%AddedHistory
FATEFate Therapeutics IncCOM2,000,000$77.5M3.3%+200,000+11.1%AddedHistory
SEERSeer, Inc.COM CL A4,750,000$72.4M3.1%00.0%UnchangedHistory
MORFMorphic Holding, Inc.COM1,650,000$66.2M2.8%+64,951+4.1%AddedHistory
Bellus Health Inc New07987C204COM NEW8,500,000$58.5M2.5%00.0%Unchanged–
IGMSIGM Biosciences, Inc.COM2,000,000$53.5M2.3%+500,000+33.3%AddedHistory
CERECerevel Therapeutics Holdings, Inc.COM1,500,000$52.5M2.2%00.0%UnchangedHistory
SWTXSpringWorks Therapeutics, Inc.COM850,000$48.0M2.0%00.0%UnchangedHistory
KYMRKymera Therapeutics, Inc.COM1,000,000$42.3M1.8%00.0%UnchangedHistory
FOLDAmicus Therapeutics, Inc.COM4,000,000$37.9M1.6%−2,000,000−33.3%ReducedHistory
CYTKCytokinetics IncCOM NEW1,000,000$36.8M1.6%00.0%UnchangedHistory
KRYSKrystal Biotech, Inc.COM500,000$33.3M1.4%−200,000−28.6%ReducedHistory
SRRKScholar Rock Holding CorpCOM2,450,000$31.6M1.3%00.0%UnchangedHistory
ERASErasca, Inc.COM3,172,221$27.3M1.2%00.0%UnchangedHistory
FHTXFoghorn Therapeutics Inc.COM1,720,720$26.2M1.1%00.0%UnchangedHistory
SAGESage Therapeutics, Inc.COM750,000$24.8M1.0%−250,000−25.0%ReducedHistory
SDGRSchrodinger, Inc.COM700,000$23.9M1.0%00.0%UnchangedHistory
RLAYRelay Therapeutics, Inc.COM700,000$21.0M0.9%−50,000−6.7%ReducedHistory
GBIOGeneration Bio Co.COM2,814,191$20.7M0.9%00.0%UnchangedHistory
GOSSGossamer Bio, Inc.COM2,358,968$20.5M0.9%00.0%UnchangedHistory
RUBYRubius Therapeutics, Inc.COM3,701,580$20.4M0.9%00.0%UnchangedHistory
TRMLTourmaline Bio, Inc.COM2,064,262$20.3M0.9%00.0%UnchangedHistory
NTLAIntellia Therapeutics, Inc.COM275,000$20.0M0.8%00.0%UnchangedHistory
DNLIDenali Therapeutics Inc.COM600,000$19.3M0.8%00.0%UnchangedHistory
PTGXProtagonist Therapeutics, IncCOM800,100$18.9M0.8%−449,900−36.0%ReducedHistory
EVOEvotec SESPONSORED ADS1,149,425$17.4M0.7%00.0%UnchangedHistory
KURAKura Oncology, Inc.COM1,050,000$16.9M0.7%00.0%UnchangedHistory
EQRXEQRx, Inc.COM4,000,000$16.5M0.7%00.0%UnchangedHistory
KLRSKalaris Therapeutics, Inc.COM2,323,371$15.7M0.7%00.0%UnchangedHistory
REPLReplimune Group, Inc.COM900,000$15.3M0.6%00.0%UnchangedHistory
OMGAOmega Therapeutics, Inc.COMMON STOCK2,273,530$14.2M0.6%00.0%UnchangedHistory
APTXAptinyx Inc.COM6,116,493$13.9M0.6%00.0%UnchangedHistory
NBPNovaBridge BiosciencesSPONSORED ADS850,000$13.8M0.6%00.0%UnchangedHistory
AGENAgenus IncCOM NEW5,500,000$13.5M0.6%−1,000,000−15.4%ReducedHistory
ITOSiTeos Therapeutics, Inc.COM400,000$12.9M0.5%−144,047−26.5%ReducedHistory
AUPHAurinia Pharmaceuticals Inc.COM1,000,000$12.4M0.5%00.0%UnchangedHistory
PRAXPraxis Precision Medicines, Inc.COM1,200,000$12.3M0.5%00.0%UnchangedHistory
KRONKronos Bio, Inc.COM1,542,954$11.2M0.5%00.0%UnchangedHistory
APLSApellis Pharmaceuticals, Inc.COM200,000$10.2M0.4%+200,000NewHistory
RPTXRepare Therapeutics Inc.COM700,000$9.97M0.4%00.0%UnchangedHistory
IMAImageneBio, Inc.COM1,549,513$9.45M0.4%00.0%UnchangedHistory
MRNSMarinus Pharmaceuticals, Inc.COM NEW1,000,000$9.35M0.4%00.0%UnchangedHistory
FMTXForma Therapeutics Holdings, Inc.SHS1,000,000$9.30M0.4%00.0%UnchangedHistory
ATRAAtara Biotherapeutics, Inc.COM1,000,000$9.29M0.4%−500,000−33.3%ReducedHistory
VERVVerve Therapeutics, Inc.COM400,000$9.13M0.4%00.0%UnchangedHistory
AMAMAmbrx Biopharma Cayman, Inc.SPONSORED ADS2,152,291$8.87M0.4%00.0%UnchangedHistory
MRSNMersana Therapeutics, Inc.COM2,200,000$8.78M0.4%+1,000,000+83.3%AddedHistory
ALXOAlx Oncology Holdings IncCOM500,000$8.45M0.4%00.0%UnchangedHistory
Exscientia PLC30223G102ADS550,000$7.92M0.3%00.0%Unchanged–
IMUXImmunic, Inc.COM700,000$7.91M0.3%00.0%UnchangedHistory
VIGLVigil Neuroscience, Inc.COM1,121,191$7.88M0.3%+1,121,191NewHistory
OVIDOvid Therapeutics Inc.COM2,500,000$7.85M0.3%00.0%UnchangedHistory
SQZSQZ Biotechnologies CoCOM1,606,309$7.73M0.3%00.0%UnchangedHistory
TGTXTG Therapeutics, Inc.COM800,000$7.61M0.3%00.0%UnchangedHistory
OTLYOatly Group ABSPONSORED ADS1,500,000$7.51M0.3%00.0%UnchangedHistory
NBTXNanobiotix S.A.SPONSORED ADS1,000,000$7.44M0.3%00.0%UnchangedHistory
Omega Alpha SpacG6749V107CL A750,000$7.37M0.3%00.0%Unchanged–
CYPHCypherpunk Technologies Inc.COM4,000,000$7.00M0.3%00.0%UnchangedHistory
SESea LtdSPONSORD ADS57,500$6.89M0.3%+57,500NewHistory
TSHATaysha Gene Therapies, Inc.COM SHS1,040,882$6.79M0.3%00.0%UnchangedHistory
Achilles Therapeutics PLC00449L102SPONSORED ADS2,255,375$6.63M0.3%00.0%Unchanged–
DSGNDesign Therapeutics, Inc.COM400,000$6.46M0.3%00.0%UnchangedHistory
IMCRImmunocore Holdings plcADS200,000$5.98M0.3%00.0%UnchangedHistory
FUSNFusion Pharmaceuticals Inc.COM750,000$5.83M0.2%00.0%UnchangedHistory
CFRXCONTRAFECT CorpCOM NEW1,500,000$5.47M0.2%00.0%UnchangedHistory
ALPNAlpine Immune Sciences, Inc.COM593,030$5.32M0.2%00.0%UnchangedHistory
STOKStoke Therapeutics, Inc.COM250,000$5.26M0.2%00.0%UnchangedHistory
DYNDyne Therapeutics, Inc.COM525,000$5.06M0.2%00.0%UnchangedHistory
NEXINexImmune, Inc.COM1,200,000$5.05M0.2%00.0%UnchangedHistory
HARPHarpoon Therapeutics, Inc.COM1,000,000$4.97M0.2%00.0%UnchangedHistory
Dynamics Special Purpose Cor268010105CLASS A COM500,000$4.93M0.2%00.0%Unchanged–
RNACCartesian Therapeutics, Inc.COM4,000,000$4.92M0.2%00.0%UnchangedHistory
TILInstil Bio, Inc.COM450,000$4.84M0.2%00.0%UnchangedHistory
YMABY-mAbs Therapeutics, Inc.COM400,000$4.75M0.2%00.0%UnchangedHistory
Avidity Biosciences, Inc.05370A108COM250,000$4.62M0.2%00.0%Unchanged–
BDTXBlack Diamond Therapeutics, Inc.COM1,646,517$4.56M0.2%00.0%UnchangedHistory
IVVDInvivyd, Inc.COM1,000,000$4.56M0.2%+1,000,000NewHistory
SPROSpero Therapeutics, Inc.COM500,000$4.35M0.2%00.0%UnchangedHistory
HOOKHOOKIPA Pharma Inc.COM1,849,616$4.22M0.2%+1,250,000+208.5%AddedHistory
SYRSSyros Pharmaceuticals, Inc.COM3,500,000$4.17M0.2%+500,000+16.7%AddedHistory
MIRMirion Technologies, Inc.COM CL A500,000$4.04M0.2%00.0%UnchangedHistory
ACIUAC Immune SASHS1,000,000$4.00M0.2%00.0%UnchangedHistory
ADVMAdverum Biotechnologies, Inc.COM3,000,000$3.93M0.2%00.0%UnchangedHistory
PFTAPerception Capital Corp. IIICLASS A ORD SHS380,000$3.77M0.2%00.0%UnchangedHistory
SLDBSolid Biosciences Inc.COM3,000,000$3.60M0.2%00.0%UnchangedHistory
LENZLENZ Therapeutics, Inc.COM700,000$3.57M0.2%00.0%UnchangedHistory
LYELLyell Immunopharma, Inc.COM700,000$3.54M0.1%00.0%UnchangedHistory
ADAGAdagene Inc.ADS1,000,000$3.50M0.1%00.0%UnchangedHistory
VORVor Biopharma Inc.COM550,000$3.32M0.1%00.0%UnchangedHistory
SANASana Biotechnology, Inc.COM400,000$3.30M0.1%00.0%UnchangedHistory
RXRXRecursion Pharmaceuticals, Inc.CL A450,000$3.22M0.1%+250,000+125.0%AddedHistory
XLOXilio Therapeutics, Inc.COM450,000$3.18M0.1%00.0%UnchangedHistory
CRISCuris IncCOM NEW1,300,000$3.09M0.1%00.0%UnchangedHistory
GRTSGritstone bio, Inc.COM750,000$3.09M0.1%00.0%UnchangedHistory

Options (2)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Artal Group S.A. in Q1 2022
SecurityClassPutsCalls
INTCIntel CorpStock–$14.9M
SAGESage Therapeutics, Inc.COM–$8.28M

Sold out since Q4 2021 (16)

Positions held at the end of Q4 2021 that are gone from this filing.

Positions of Artal Group S.A. sold out since Q4 2021
SecurityClassShares in Q4 2021Value in Q4 2021% of portfolio in Q4 2021History
NGNovagold Resources IncCOM NEW2,600,000$17.8M0.5%History
ALBOAlbireo Pharma, Inc.COM600,000$14.0M0.4%History
TPTXTurning Point Therapeutics, Inc.COM250,000$11.9M0.4%History
EVLOEvelo Biosciences, Inc.COM1,000,000$6.07M0.2%History
SYRESpyre Therapeutics, Inc.COM1,045,000$4.96M0.1%History
GDSGDS Holdings LtdSPONSORED ADS100,000$4.72M0.1%History
IQiQIYI, Inc.SPONSORED ADS1,000,000$4.56M0.1%History
PHATPhathom Pharmaceuticals, Inc.COM200,000$3.93M0.1%History
KDNYChinook Therapeutics, Inc.COM180,500$2.94M0.1%History
Amryt Pharma PLC03217L106SPONSORED ADS150,480$1.63M<0.1%–
DCPHDeciphera Pharmaceuticals, Inc.COM100,000$977.0K<0.1%History
RIGLRigel Pharmaceuticals IncCOM NEW321,100$851.0K<0.1%History
MBIIPro Farm Group, Inc.COM1,048,679$755.0K<0.1%History
RIVNRivian Automotive, Inc.Stock7,000$726.0K<0.1%History
DLOdLocal LtdCLASS A COM20,000$714.0K<0.1%History
SURFSurface Oncology, Inc.COM100,000$478.0K<0.1%History