| DekaBank Deutsche Girozentrale | 17,000 | $293.0 萬 | 0.01% | 00.0% | 不變 |
| IFP Advisors, Inc | 300 | $5.17 萬 | 0.00% | 00.0% | 不變 |
| CPMG Inc | 0 | $0 | 0.00% | −2,896,901−100.0% | 清倉 |
| Vanguard Group Inc | 0 | $0 | 0.00% | −2,821,537−100.0% | 清倉 |
| BlackRock Inc. | 0 | $0 | 0.00% | −2,538,770−100.0% | 清倉 |
| Adage Capital Partners GP, L.L.C. | 0 | $0 | 0.00% | −1,766,070−100.0% | 清倉 |
| Deutsche Bank AG | 0 | $0 | 0.00% | −1,486,467−100.0% | 清倉 |
| Wellington Management Group LLP | 0 | $0 | 0.00% | −1,472,043−100.0% | 清倉 |
| First Light Asset Management, LLC | 0 | $0 | 0.00% | −1,432,208−100.0% | 清倉 |
| Boxer Capital, LLC | 0 | $0 | 0.00% | −1,430,004−100.0% | 清倉 |
| Janus Henderson Group PLC | 0 | $0 | 0.00% | −1,051,077−100.0% | 清倉 |
| State Street Corp | 0 | $0 | 0.00% | −713,150−100.0% | 清倉 |
| Perceptive Advisors LLC | 0 | $0 | 0.00% | −670,206−100.0% | 清倉 |
| Holocene Advisors, LP | 0 | $0 | 0.00% | −667,950−100.0% | 清倉 |
| Geode Capital Management, LLC | 0 | $0 | 0.00% | −593,430−100.0% | 清倉 |
| Citadel Advisors LLC | 0 | $0 | 0.00% | −571,529−100.0% | 清倉 |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −568,151−100.0% | 清倉 |
| Millennium Management LLC | 0 | $0 | 0.00% | −556,264−100.0% | 清倉 |
| Farallon Capital Management, L.L.C. | 0 | $0 | 0.00% | −451,700−100.0% | 清倉 |
| Fred Alger Management, LLC | 0 | $0 | 0.00% | −407,170−100.0% | 清倉 |
| TimesSquare Capital Management, LLC | 0 | $0 | 0.00% | −344,580−100.0% | 清倉 |
| Blackstone Group Inc. | 0 | $0 | 0.00% | −340,793−100.0% | 清倉 |
| Invesco Ltd. | 0 | $0 | 0.00% | −340,654−100.0% | 清倉 |
| Voya Investment Management LLC | 0 | $0 | 0.00% | −329,189−100.0% | 清倉 |
| Sofinnova Investments, Inc. | 0 | $0 | 0.00% | −322,471−100.0% | 清倉 |
| Emerald Advisers, LLC | 0 | $0 | 0.00% | −317,096−100.0% | 清倉 |
| Voloridge Investment Management, LLC | 0 | $0 | 0.00% | −311,358−100.0% | 清倉 |
| FMR LLC | 0 | $0 | 0.00% | −305,225−100.0% | 清倉 |
| Price T Rowe Associates Inc | 0 | $0 | 0.00% | −295,741−100.0% | 清倉 |
| Northern Trust Corp | 0 | $0 | 0.00% | −287,968−100.0% | 清倉 |
| Emerald Mutual Fund Advisers Trust | 0 | $0 | 0.00% | −255,387−100.0% | 清倉 |
| MPM Oncology Impact Management LP | 0 | $0 | 0.00% | −234,478−100.0% | 清倉 |
| Goldman Sachs Group Inc | 0 | $0 | 0.00% | −218,143−100.0% | 清倉 |
| Charles Schwab Investment Management Inc | 0 | $0 | 0.00% | −216,012−100.0% | 清倉 |
| Victory Capital Management Inc | 0 | $0 | 0.00% | −211,931−100.0% | 清倉 |
| JPMorgan Chase & Co | 0 | $0 | 0.00% | −206,223−100.0% | 清倉 |
| Woodline Partners LP | 0 | $0 | 0.00% | −205,108−100.0% | 清倉 |
| Braun Stacey Associates Inc | 0 | $0 | 0.00% | −164,775−100.0% | 清倉 |
| Morgan Stanley | 0 | $0 | 0.00% | −162,905−100.0% | 清倉 |
| Norges Bank | 0 | $0 | 0.00% | −145,582−100.0% | 清倉 |
| PFM Health Sciences, LP | 0 | $0 | 0.00% | −145,147−100.0% | 清倉 |
| Bank of New York Mellon Corp | 0 | $0 | 0.00% | −132,343−100.0% | 清倉 |
| Alliancebernstein L.P. | 0 | $0 | 0.00% | −131,235−100.0% | 清倉 |
| Ensign Peak Advisors, Inc | 0 | $0 | 0.00% | −126,625−100.0% | 清倉 |
| Integral Health Asset Management, LLC | 0 | $0 | 0.00% | −120,000−100.0% | 清倉 |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −114,520−100.0% | 清倉 |
| Two Sigma Investments, LP | 0 | $0 | 0.00% | −109,131−100.0% | 清倉 |
| Suvretta Capital Management, LLC | 0 | $0 | 0.00% | −108,832−100.0% | 清倉 |
| Ally Bridge Group (NY) LLC | 0 | $0 | 0.00% | −105,558−100.0% | 清倉 |
| Frazier Life Sciences Management, L.P. | 0 | $0 | 0.00% | −100,430−100.0% | 清倉 |
| Soleus Capital Management, L.P. | 0 | $0 | 0.00% | −97,547−100.0% | 清倉 |
| Tri Locum Partners LP | 0 | $0 | 0.00% | −96,274−100.0% | 清倉 |
| Driehaus Capital Management LLC | 0 | $0 | 0.00% | −94,945−100.0% | 清倉 |
| Skandinaviska Enskilda Banken AB (publ) | 0 | $0 | 0.00% | −94,646−100.0% | 清倉 |
| Nuveen Asset Management, LLC | 0 | $0 | 0.00% | −94,039−100.0% | 清倉 |
| Ameriprise Financial Inc | 0 | $0 | 0.00% | −89,771−100.0% | 清倉 |
| Bank of America Corp | 0 | $0 | 0.00% | −87,846−100.0% | 清倉 |
| Ghost Tree Capital, LLC | 0 | $0 | 0.00% | −85,000−100.0% | 清倉 |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −84,508−100.0% | 清倉 |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −84,059−100.0% | 清倉 |
| Polar Asset Management Partners Inc. | 0 | $0 | 0.00% | −83,400−100.0% | 清倉 |
| Barclays PLC | 0 | $0 | 0.00% | −79,034−100.0% | 清倉 |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −70,516−100.0% | 清倉 |
| King Luther Capital Management Corp | 0 | $0 | 0.00% | −65,534−100.0% | 清倉 |
| BNP Paribas Arbitrage, SA | 0 | $0 | 0.00% | −56,365−100.0% | 清倉 |
| Swiss National Bank | 0 | $0 | 0.00% | −52,400−100.0% | 清倉 |
| Moody Aldrich Partners LLC | 0 | $0 | 0.00% | −51,533−100.0% | 清倉 |
| Alyeska Investment Group, L.P. | 0 | $0 | 0.00% | −50,982−100.0% | 清倉 |
| Rhumbline Advisers | 0 | $0 | 0.00% | −48,033−100.0% | 清倉 |
| HighTower Advisors, LLC | 0 | $0 | 0.00% | −47,574−100.0% | 清倉 |
| Sectoral Asset Management Inc | 0 | $0 | 0.00% | −47,500−100.0% | 清倉 |
| Hennion & Walsh Asset Management, Inc. | 0 | $0 | 0.00% | −43,316−100.0% | 清倉 |
| Credit Suisse AG | 0 | $0 | 0.00% | −42,577−100.0% | 清倉 |
| SEI Investments Co | 0 | $0 | 0.00% | −41,890−100.0% | 清倉 |
| Altium Capital Management LP | 0 | $0 | 0.00% | −41,485−100.0% | 清倉 |
| Hudson Bay Capital Management LP | 0 | $0 | 0.00% | −40,000−100.0% | 清倉 |
| UBS Group AG | 0 | $0 | 0.00% | −39,027−100.0% | 清倉 |
| CenterBook Partners LP | 0 | $0 | 0.00% | −34,878−100.0% | 清倉 |
| Tolleson Wealth Management, Inc. | 0 | $0 | 0.00% | −33,250−100.0% | 清倉 |
| California State Teachers Retirement System | 0 | $0 | 0.00% | −30,693−100.0% | 清倉 |
| Fayez Sarofim & Co | 0 | $0 | 0.00% | −30,329−100.0% | 清倉 |
| First Trust Advisors LP | 0 | $0 | 0.00% | −29,611−100.0% | 清倉 |
| Affinity Asset Advisors, LLC | 0 | $0 | 0.00% | −29,105−100.0% | 清倉 |
| KRS Capital Management, LLC | 0 | $0 | 0.00% | −27,941−100.0% | 清倉 |
| State of Wisconsin Investment Board | 0 | $0 | 0.00% | −27,437−100.0% | 清倉 |
| State of New Jersey Common Pension Fund D | 0 | $0 | 0.00% | −26,606−100.0% | 清倉 |
| LBJ Family Wealth Advisors, Ltd. | 0 | $0 | 0.00% | −25,604−100.0% | 清倉 |
| Bridger Management, LLC | 0 | $0 | 0.00% | −24,800−100.0% | 清倉 |
| Prime Capital Investment Advisors, LLC | 0 | $0 | 0.00% | −24,550−100.0% | 清倉 |
| Legal & General Group Plc | 0 | $0 | 0.00% | −23,498−100.0% | 清倉 |
| UBS Asset Management Americas Inc | 0 | $0 | 0.00% | −25,836−100.0% | 清倉 |
| Erste Asset Management GmbH | 0 | $0 | 0.00% | −23,000−100.0% | 清倉 |
| Bank of Montreal | 0 | $0 | 0.00% | −22,595−100.0% | 清倉 |
| Wallace Capital Management Inc. | 0 | $0 | 0.00% | −22,175−100.0% | 清倉 |
| Atika Capital Management LLC | 0 | $0 | 0.00% | −22,000−100.0% | 清倉 |
| HighMark Wealth Management LLC | 0 | $0 | 0.00% | −21,219−100.0% | 清倉 |
| Madden Securities Corp | 0 | $0 | 0.00% | −21,000−100.0% | 清倉 |
| TCTC Holdings, LLC | 0 | $0 | 0.00% | −20,982−100.0% | 清倉 |
| Harvest Investment Services, LLC | 0 | $0 | 0.00% | −18,655−100.0% | 清倉 |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −17,884−100.0% | 清倉 |
