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Zentalis Pharmaceuticals, Inc.

ZNTL
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001725160

In the last 90 days, Zentalis Pharmaceuticals, Inc. insiders filed 1 open-market purchase and 0 sales; 114 institutions reported holding it in 13F filings for Q2 2026, worth $228.9M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Zentalis Pharmaceuticals, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
102
+17 vs. Q4 2025
Shares held
43.6M
+5.83M (+15.4%) vs. Q4 2025
Total value
$101.7M
+$50.6M (+99.1%) vs. Q4 2025
New holders
27
30 more added
Sold out
10
28 more reduced

1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ZNTL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 102 institutions
Q1 2021: 95 institutionsQ2 2021: 120 institutionsQ3 2021: 116 institutionsQ4 2021: 139 institutionsQ1 2022: 128 institutionsQ2 2022: 122 institutionsQ3 2022: 121 institutionsQ4 2022: 106 institutionsQ1 2023: 110 institutionsQ2 2023: 134 institutionsQ3 2023: 137 institutionsQ4 2023: 120 institutionsQ1 2024: 142 institutionsQ2 2024: 145 institutionsQ3 2024: 136 institutionsQ4 2024: 142 institutionsQ1 2025: 132 institutionsQ2 2025: 117 institutionsQ3 2025: 99 institutionsQ4 2025: 86 institutionsQ1 2026: 102 institutionsQ2 2026: 114 institutions
Value heldQ1 2026: $101.7M
Q1 2021: $1.58BQ2 2021: $2.13BQ3 2021: $2.75BQ4 2021: $3.61BQ1 2022: $2.05BQ2 2022: $1.64BQ3 2022: $1.27BQ4 2022: $1.30BQ1 2023: $1.15BQ2 2023: $2.32BQ3 2023: $1.61BQ4 2023: $1.23BQ1 2024: $1.34BQ2 2024: $314.3MQ3 2024: $261.2MQ4 2024: $195.2MQ1 2025: $92.9MQ2 2025: $64.5MQ3 2025: $79.7MQ4 2025: $54.9MQ1 2026: $101.7MQ2 2026: $228.9M
Institutions holding ZNTL and their total value by quarter
QuarterHoldersValue
Q2 2026114$228.9M
Q1 2026102$101.7M
Q4 202586$54.9M
Q3 202599$79.7M
Q2 2025117$64.5M
Q1 2025132$92.9M
Q4 2024142$195.2M
Q3 2024136$261.2M
Q2 2024145$314.3M
Q1 2024142$1.34B
Q4 2023120$1.23B
Q3 2023137$1.61B
Q2 2023134$2.32B
Q1 2023110$1.15B
Q4 2022106$1.30B
Q3 2022121$1.27B
Q2 2022122$1.64B
Q1 2022128$2.05B
Q4 2021139$3.61B
Q3 2021116$2.75B
Q2 2021120$2.13B
Q1 202195$1.58B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Zentalis Pharmaceuticals, Inc.; share changes are against Q4 2025.

Institutions holding ZNTL in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
5AM Venture Management, LLC3,947,913$9.24M2.56%00.0%Unchanged
Squadron Capital Management LLC3,631,000$8.50M3.40%+3,631,000New
Two Sigma Investments, LP2,956,526$6.92M0.01%+1,485,112+100.9%Added
Acadian Asset Management LLC2,848,252$6.66M0.01%−1,0420.0%Reduced
Vanguard Capital Management LLC2,310,707$5.41M0.00%+2,310,707New
Renaissance Technologies LLC1,938,145$4.54M0.01%−945,600−32.8%Reduced
Citadel Advisors LLC1,732,083$4.05M0.00%−232,172−11.8%Reduced
D. E. Shaw & Co., Inc.1,484,098$3.47M0.00%−176,280−10.6%Reduced
Opaleye Management Inc.1,412,656$3.31M0.44%+11,750+0.8%Added
Decheng Capital LLC1,323,327$3.10M0.47%00.0%Unchanged
Millennium Management LLC1,289,822$3.02M0.00%+616,693+91.6%Added
BlackRock, Inc.1,269,837$2.97M0.00%+19,869+1.6%Added
Ishara Investments LP1,230,000$2.88M2.91%−90,000−6.8%Reduced
Bank of America Corp1,132,294$2.65M0.00%−234,960−17.2%Reduced
Primecap Management Co957,420$2.24M0.00%00.0%Unchanged
Pfizer Inc953,834$2.00M0.84%00.0%Unchanged
Connor, Clark & Lunn Investment Management Ltd.792,001$1.85M0.00%+4,946+0.6%Added
Qube Research & Technologies Ltd637,116$1.49M0.00%+619,645+3,546.7%Added
Geode Capital Management, LLC621,036$1.45M0.00%+31,931+5.4%Added
Gsa Capital Partners LLP620,407$1.45M0.09%−549,166−47.0%Reduced
Almitas Capital LLC610,073$1.43M0.32%00.0%Unchanged
Barclays PLC591,217$1.38M0.00%+22,774+4.0%Added
Susquehanna International Group, LLP571,257$1.34M0.00%+560,914+5,423.1%Added
Jane Street Group, LLC490,339$1.15M0.00%+17,164+3.6%Added
BNP Paribas Arbitrage, SA471,438$1.10M0.00%+52,071+12.4%Added
Goldman Sachs Group Inc462,678$1.08M0.00%+344,466+291.4%Added
Marshall Wace, LLP392,643$918.8K0.00%+144,855+58.5%Added
Vanguard Portfolio Management LLC360,600$843.8K0.00%+360,600New
Peapod Lane Capital LLC366,868$834.6K0.68%−81,993−18.3%Reduced
Morgan Stanley350,207$819.5K0.00%−453,447−56.4%Reduced
XTX Topco Ltd322,507$754.7K0.01%−254,200−44.1%Reduced
Vanguard Fiduciary Trust Co304,471$712.5K0.00%+304,471New
Creative Planning285,000$666.9K0.00%+25,000+9.6%Added
FMR LLC283,917$664.4K0.00%+40,609+16.7%Added
CDC Financial, Inc.283,762$664.0K0.55%+283,762New
Anfield Capital Management, LLC274,516$642.4K0.18%+31,911+13.2%Added
Dimensional Fund Advisors LP272,034$634.3K0.00%+175,771+182.6%Added
Stonepine Capital Management, LLC269,100$629.7K0.55%−194,600−42.0%Reduced
Woodline Partners LP266,032$622.5K0.00%−264,550−49.9%Reduced
State Street Corp249,690$584.3K0.00%−22,100−8.1%Reduced
SEI Investments Co191,551$448.2K0.00%+24,451+14.6%Added
UBS Group AG155,704$364.3K0.00%−518,894−76.9%Reduced
Quarry LP150,000$351.0K0.07%+18,000+13.6%Added
ADAR1 Capital Management, LLC144,636$338.4K0.02%+64,636+80.8%Added
Panagora Asset Management Inc139,690$326.9K0.00%+53,050+61.2%Added
Invesco Ltd.125,767$294.3K0.00%−62,815−33.3%Reduced
Northern Trust Corp118,186$276.6K0.00%+25,315+27.3%Added
Hudson Bay Capital Management LP117,127$274.1K0.00%+117,127New
Barr E S & Co110,000$257.4K0.01%+52,500+91.3%Added
Seven Fleet Capital Management LP110,000$257.4K0.08%+110,000New
JPMorgan Chase & Co113,126$242.1K0.00%−71,881−38.9%Reduced
Simplex Trading, LLC98,554$230.6K0.01%+98,554New
Point72 Asset Management, L.P.94,854$222.0K0.00%−5,436−5.4%Reduced
Graham Capital Management, L.P.92,427$216.3K0.01%+1,517+1.7%Added
Wealth Enhancement Advisory Services, LLC78,740$207.1K0.00%−51,667−39.6%Reduced
Bridgeway Capital Management, LLC77,300$180.9K0.00%00.0%Unchanged
Citigroup Inc77,255$180.8K0.00%+77,255New
49 Wealth Management, LLC66,401$155.4K0.01%−4,510−6.4%Reduced
Federated Hermes, Inc.65,520$153.3K0.00%+30,946+89.5%Added
Commonwealth Equity Services, LLC61,412$143.7K0.00%00.0%Unchanged
HRT Financial LP52,185$122.0K0.00%+52,185New
Charles Schwab Investment Management Inc51,087$119.5K0.00%+51,087New
RBF Capital, LLC50,000$117.0K0.01%−30,000−37.5%Reduced
American Century Companies Inc48,572$113.7K0.00%+35,692+277.1%Added
Omers Administration Corp47,700$111.6K0.00%+47,700New
Brevan Howard Capital Management LP47,063$110.1K0.00%+47,063New
Tudor Investment Corp Et Al34,849$81.5K0.00%00.0%Unchanged
Quadrature Capital Ltd33,332$78.0K0.00%−104,236−75.8%Reduced
Private Advisor Group, LLC31,472$73.6K0.00%+31,472New
Squarepoint Ops LLC30,691$71.8K0.00%−77,043−71.5%Reduced
Headlands Technologies LLC29,899$70.0K0.01%+29,899New
Regency Capital Management Inc.29,500$69.0K0.03%00.0%Unchanged
State of Wyoming28,466$66.6K0.01%+28,466New
Carson Advisory Inc.23,270$54.5K0.03%−200−0.9%Reduced
Raymond James Financial Inc22,895$53.6K0.00%+3,000+15.1%Added
AQR Capital Management LLC22,675$53.1K0.00%−23,320−50.7%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH22,447$52.5K0.00%−28,614−56.0%Reduced
Vanguard Global Advisers, LLC21,725$50.8K0.00%+21,725New
Prudential Financial Inc20,850$48.8K0.00%−3,700−15.1%Reduced
Schonfeld Strategic Advisors LLC20,600$48.2K0.00%+20,600New
Prelude Capital Management, LLC20,400$47.7K0.00%+20,400New
Sivia Capital Partners, LLC20,000$46.8K0.01%00.0%Unchanged
Birchview Capital, LP17,503$41.0K0.02%+503+3.0%Added
Evergreen Capital Management LLC16,915$39.6K0.00%00.0%Unchanged
Catalyst Funds Management Pty Ltd16,700$39.1K0.01%+16,700New
CTC Alternative Strategies, Ltd.12,500$29.3K0.07%+12,500New
Shay Capital LLC10,662$24.9K0.00%00.0%Unchanged
Cornerstone Wealth Management, LLC10,186$23.8K0.00%+10,186New
CWM, LLC5,377$12.6K0.00%−3,187−37.2%Reduced
EverSource Wealth Advisors, LLC1,699$3.98K0.00%+55+3.3%Added
Group One Trading, L.P.1,460$3.42K0.00%+1,460New
Tower Research Capital LLC (TRC)1,134$2.65K0.00%+1,134New
Bryn Mawr Trust Co1,000$2.34K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC387$9060.00%00.0%Unchanged
Fortitude Family Office, LLC209$4890.00%+209New
HighMark Wealth Management LLC130$3040.00%00.0%Unchanged
Silicon Valley Capital Partners84$1970.00%+84New
Optiver Holding B.V.44$1030.00%00.0%Unchanged
SBI Securities Co., Ltd.27$630.00%00.0%Unchanged
CWM Advisors, LLC21$500.00%+5+31.3%Added