Skip to main content

Zentalis Pharmaceuticals, Inc.

ZNTL
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001725160

In the last 90 days, Zentalis Pharmaceuticals, Inc. insiders filed 1 open-market purchase and 0 sales; 114 institutions reported holding it in 13F filings for Q2 2026, worth $228.9M in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Zentalis Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
99
−18 vs. Q2 2025
Shares held
52.8M
−2.82M (−5.1%) vs. Q2 2025
Total value
$79.7M
+$15.2M (+23.5%) vs. Q2 2025
New holders
5
36 more added
Sold out
23
33 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ZNTL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 99 institutions
Q1 2021: 95 institutionsQ2 2021: 120 institutionsQ3 2021: 116 institutionsQ4 2021: 139 institutionsQ1 2022: 128 institutionsQ2 2022: 122 institutionsQ3 2022: 121 institutionsQ4 2022: 106 institutionsQ1 2023: 110 institutionsQ2 2023: 134 institutionsQ3 2023: 137 institutionsQ4 2023: 120 institutionsQ1 2024: 142 institutionsQ2 2024: 145 institutionsQ3 2024: 136 institutionsQ4 2024: 142 institutionsQ1 2025: 132 institutionsQ2 2025: 117 institutionsQ3 2025: 99 institutionsQ4 2025: 86 institutionsQ1 2026: 102 institutionsQ2 2026: 114 institutions
Value heldQ3 2025: $79.7M
Q1 2021: $1.58BQ2 2021: $2.13BQ3 2021: $2.75BQ4 2021: $3.61BQ1 2022: $2.05BQ2 2022: $1.64BQ3 2022: $1.27BQ4 2022: $1.30BQ1 2023: $1.15BQ2 2023: $2.32BQ3 2023: $1.61BQ4 2023: $1.23BQ1 2024: $1.34BQ2 2024: $314.3MQ3 2024: $261.2MQ4 2024: $195.2MQ1 2025: $92.9MQ2 2025: $64.5MQ3 2025: $79.7MQ4 2025: $54.9MQ1 2026: $101.7MQ2 2026: $228.9M
Institutions holding ZNTL and their total value by quarter
QuarterHoldersValue
Q2 2026114$228.9M
Q1 2026102$101.7M
Q4 202586$54.9M
Q3 202599$79.7M
Q2 2025117$64.5M
Q1 2025132$92.9M
Q4 2024142$195.2M
Q3 2024136$261.2M
Q2 2024145$314.3M
Q1 2024142$1.34B
Q4 2023120$1.23B
Q3 2023137$1.61B
Q2 2023134$2.32B
Q1 2023110$1.15B
Q4 2022106$1.30B
Q3 2022121$1.27B
Q2 2022122$1.64B
Q1 2022128$2.05B
Q4 2021139$3.61B
Q3 2021116$2.75B
Q2 2021120$2.13B
Q1 202195$1.58B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Zentalis Pharmaceuticals, Inc.; share changes are against Q2 2025.

Institutions holding ZNTL in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Matrix Capital Management Company, LP13,959,973$21.1M19.75%00.0%Unchanged
Vanguard Group Inc2,904,400$4.39M0.00%+19,768+0.7%Added
Acadian Asset Management LLC2,845,152$4.29M0.01%+46,132+1.6%Added
Renaissance Technologies LLC2,325,355$3.51M0.00%+795,802+52.0%Added
Citadel Advisors LLC2,077,290$3.14M0.00%+1,614,950+349.3%Added
Tang Capital Management LLC1,550,000$2.34M0.09%00.0%Unchanged
Bank of America Corp1,548,781$2.34M0.00%+835,466+117.1%Added
Two Sigma Advisers, LP1,461,200$2.21M0.00%+185,286+14.5%Added
D. E. Shaw & Co., Inc.1,408,803$2.13M0.00%+211,179+17.6%Added
Morgan Stanley1,407,829$2.13M0.00%+310,178+28.3%Added
Two Sigma Investments, LP1,363,347$2.06M0.00%+270,294+24.7%Added
Decheng Capital LLC1,323,327$2.00M0.35%00.0%Unchanged
BlackRock, Inc.1,249,504$1.89M0.00%−492,243−28.3%Reduced
Balyasny Asset Management LLC1,185,521$1.79M0.00%+214,659+22.1%Added
Gsa Capital Partners LLP1,077,656$1.63M0.14%−55,719−4.9%Reduced
Primecap Management Co962,620$1.45M0.00%−65,000−6.3%Reduced
Tybourne Capital Management (HK) Ltd961,486$1.45M4.69%−516,666−35.0%Reduced
Pfizer Inc953,834$1.44M0.33%00.0%Unchanged
Millennium Management LLC902,521$1.36M0.00%−2,574,287−74.0%Reduced
JPMorgan Chase & Co723,075$1.09M0.00%+172,628+31.4%Added
Jacobs Levy Equity Management, Inc700,576$1.06M0.00%−157,006−18.3%Reduced
Jane Street Group, LLC645,623$974.9K0.00%−18,438−2.8%Reduced
Geode Capital Management, LLC589,222$890.2K0.00%−28,945−4.7%Reduced
Peapod Lane Capital LLC565,371$853.9K0.76%+6,158+1.1%Added
XTX Topco Ltd548,629$828.4K0.04%+283,800+107.2%Added
UBS Group AG532,678$804.3K0.00%+403,210+311.4%Added
Woodline Partners LP530,582$801.2K0.00%00.0%Unchanged
5AM Venture Management, LLC490,000$739.9K0.27%00.0%Unchanged
Almitas Capital LLC457,322$690.6K0.16%−1,141,944−71.4%Reduced
Stonepine Capital Management, LLC453,800$685.2K0.56%+344,790+316.3%Added
Connor, Clark & Lunn Investment Management Ltd.380,822$575.0K0.00%+65,977+21.0%Added
Goldman Sachs Group Inc345,155$521.2K0.00%−516,612−59.9%Reduced
Opaleye Management Inc.316,550$478.0K0.07%−1,607,750−83.5%Reduced
State Street Corp271,790$410.4K0.00%00.0%Unchanged
Creative Planning260,000$392.6K0.00%+229,660+757.0%Added
FMR LLC203,305$307.0K0.00%+18,628+10.1%Added
Susquehanna International Group, LLP201,109$303.7K0.00%+55,340+38.0%Added
Dimensional Fund Advisors LP185,032$279.4K0.00%−150,934−44.9%Reduced
Invesco Ltd.173,621$262.2K0.00%+17,907+11.5%Added
Wealth Enhancement Advisory Services, LLC166,290$257.8K0.00%−7,716−4.4%Reduced
SEI Investments Co167,100$252.3K0.00%00.0%Unchanged
Barclays PLC161,470$243.8K0.00%+161,469+16,146,900.0%Added
BNP Paribas Arbitrage, SA158,935$240.0K0.00%−14,549−8.4%Reduced
Graham Capital Management, L.P.152,147$229.7K0.01%+116,672+328.9%Added
Walleye Capital LLC120,448$181.9K0.00%−9,419−7.3%Reduced
Quarry LP108,750$164.2K0.04%+3,750+3.6%Added
AQR Capital Management LLC106,965$161.5K0.00%−327,993−75.4%Reduced
Panagora Asset Management Inc97,898$147.8K0.00%+97,898New
Northern Trust Corp94,119$142.1K0.00%−29,325−23.8%Reduced
RBF Capital, LLC80,000$120.8K0.01%00.0%Unchanged
Bridgeway Capital Management, LLC77,300$116.7K0.00%00.0%Unchanged
Anfield Capital Management, LLC71,377$107.8K0.03%00.0%Unchanged
Cubist Systematic Strategies, LLC70,609$106.6K0.00%−249,709−78.0%Reduced
Quadrature Capital Ltd60,651$92.2K0.00%+8,195+15.6%Added
Commonwealth Equity Services, LLC60,987$92.0K0.00%00.0%Unchanged
Qube Research & Technologies Ltd56,639$85.5K0.00%+24,526+76.4%Added
Ameriprise Financial Inc52,572$79.4K0.00%−38,623−42.4%Reduced
Catalyst Funds Management Pty Ltd51,400$77.6K0.01%+24,600+91.8%Added
Universal- Beteiligungs- und Servicegesellschaft mbH51,061$77.1K0.00%00.0%Unchanged
ADAR1 Capital Management, LLC50,000$75.5K0.01%00.0%Unchanged
Algert Global LLC48,496$73.2K0.00%+48,496New
Charles Schwab Investment Management Inc41,981$63.4K0.00%−257,116−86.0%Reduced
Federated Hermes, Inc.41,119$62.1K0.00%+1,383+3.5%Added
Barr E S & Co40,000$60.4K0.00%00.0%Unchanged
Tudor Investment Corp Et Al34,849$52.6K0.00%00.0%Unchanged
Ieq Capital, LLC34,153$51.6K0.00%−52,147−60.4%Reduced
Carson Advisory Inc.32,070$48.4K0.03%+2,500+8.5%Added
Public Employees Retirement System of Ohio31,900$48.2K0.00%−4,800−13.1%Reduced
SG Americas Securities, LLC31,579$48.0K0.00%+8,236+35.3%Added
Bluefin Capital Management, LLC31,266$47.2K0.02%+31,266New
HRT Financial LP30,424$45.0K0.00%−83,439−73.3%Reduced
Regency Capital Management Inc.29,500$44.5K0.02%00.0%Unchanged
Tower Research Capital LLC (TRC)29,386$44.4K0.00%+12,272+71.7%Added
49 Wealth Management, LLC28,192$42.6K0.00%+6,646+30.8%Added
Voleon Capital Management LP27,161$41.0K0.00%+27,161New
Point72 Asia (Singapore) Pte. Ltd.23,874$36.0K0.01%−35,579−59.8%Reduced
Prudential Financial Inc21,600$32.6K0.00%+2,700+14.3%Added
Squarepoint Ops LLC21,322$32.2K0.00%−25,139−54.1%Reduced
Raymond James Financial Inc20,595$31.1K0.00%00.0%Unchanged
Acorn Wealth Advisors, LLC20,000$30.2K0.01%00.0%Unchanged
Birchview Capital, LP17,000$25.7K0.02%00.0%Unchanged
Evergreen Capital Management LLC16,915$25.5K0.00%00.0%Unchanged
Harvest Investment Services, LLC14,206$21.5K0.00%−11,266−44.2%Reduced
Engineers Gate Manager LP13,619$20.6K0.00%+598+4.6%Added
CWM, LLC13,118$20.0K0.00%−15,528−54.2%Reduced
Highline Wealth Partners LLC12,000$18.1K0.00%+5,000+71.4%Added
Captrust Financial Advisors10,464$15.8K0.00%−1,378−11.6%Reduced
EverSource Wealth Advisors, LLC2,593$3.92K0.00%+243+10.3%Added
Clearstead Advisors, LLC1,115$1.68K0.00%−946−45.9%Reduced
Bryn Mawr Trust Co1,000$1.51K0.00%00.0%Unchanged
Citigroup Inc906$1.37K0.00%−18,541−95.3%Reduced
Royal Bank of Canada422$1.00K0.00%−2,019−82.7%Reduced
Nisa Investment Advisors, LLC387$5840.00%00.0%Unchanged
HighMark Wealth Management LLC130$1960.00%00.0%Unchanged
Optiver Holding B.V.44$660.00%+44New
SBI Securities Co., Ltd.28$420.00%+1+3.7%Added
IFP Advisors, Inc24$360.00%−11−31.4%Reduced
Caitong International Asset Management Co., Ltd1$20.00%−2,712−100.0%Reduced
Covestor Ltd52$00.00%00.0%Unchanged
Man Group plc0$00.00%−406,344−100.0%Sold out