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Zentalis Pharmaceuticals, Inc.

ZNTL
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001725160

In the last 90 days, Zentalis Pharmaceuticals, Inc. insiders filed 1 open-market purchase and 0 sales; 114 institutions reported holding it in 13F filings for Q2 2026, worth $228.9M in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Zentalis Pharmaceuticals, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
117
−15 vs. Q1 2025
Shares held
55.6M
−2.85M (−4.9%) vs. Q1 2025
Total value
$64.5M
−$28.4M (−30.6%) vs. Q1 2025
New holders
22
34 more added
Sold out
37
44 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ZNTL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 117 institutions
Q1 2021: 95 institutionsQ2 2021: 120 institutionsQ3 2021: 116 institutionsQ4 2021: 139 institutionsQ1 2022: 128 institutionsQ2 2022: 122 institutionsQ3 2022: 121 institutionsQ4 2022: 106 institutionsQ1 2023: 110 institutionsQ2 2023: 134 institutionsQ3 2023: 137 institutionsQ4 2023: 120 institutionsQ1 2024: 142 institutionsQ2 2024: 145 institutionsQ3 2024: 136 institutionsQ4 2024: 142 institutionsQ1 2025: 132 institutionsQ2 2025: 117 institutionsQ3 2025: 99 institutionsQ4 2025: 86 institutionsQ1 2026: 102 institutionsQ2 2026: 114 institutions
Value heldQ2 2025: $64.5M
Q1 2021: $1.58BQ2 2021: $2.13BQ3 2021: $2.75BQ4 2021: $3.61BQ1 2022: $2.05BQ2 2022: $1.64BQ3 2022: $1.27BQ4 2022: $1.30BQ1 2023: $1.15BQ2 2023: $2.32BQ3 2023: $1.61BQ4 2023: $1.23BQ1 2024: $1.34BQ2 2024: $314.3MQ3 2024: $261.2MQ4 2024: $195.2MQ1 2025: $92.9MQ2 2025: $64.5MQ3 2025: $79.7MQ4 2025: $54.9MQ1 2026: $101.7MQ2 2026: $228.9M
Institutions holding ZNTL and their total value by quarter
QuarterHoldersValue
Q2 2026114$228.9M
Q1 2026102$101.7M
Q4 202586$54.9M
Q3 202599$79.7M
Q2 2025117$64.5M
Q1 2025132$92.9M
Q4 2024142$195.2M
Q3 2024136$261.2M
Q2 2024145$314.3M
Q1 2024142$1.34B
Q4 2023120$1.23B
Q3 2023137$1.61B
Q2 2023134$2.32B
Q1 2023110$1.15B
Q4 2022106$1.30B
Q3 2022121$1.27B
Q2 2022122$1.64B
Q1 2022128$2.05B
Q4 2021139$3.61B
Q3 2021116$2.75B
Q2 2021120$2.13B
Q1 202195$1.58B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Zentalis Pharmaceuticals, Inc.; share changes are against Q1 2025.

Institutions holding ZNTL in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Matrix Capital Management Company, LP13,959,973$16.2M7.27%00.0%Unchanged
Millennium Management LLC3,476,808$4.03M0.00%+407,294+13.3%Added
Vanguard Group Inc2,884,632$3.35M0.00%−375,980−11.5%Reduced
Acadian Asset Management LLC2,799,020$3.24M0.01%+124,985+4.7%Added
Opaleye Management Inc.1,924,300$2.23M0.45%−60,700−3.1%Reduced
BlackRock, Inc.1,741,747$2.02M0.00%−2,487,750−58.8%Reduced
Almitas Capital LLC1,599,266$1.86M0.47%−111,655−6.5%Reduced
Tang Capital Management LLC1,550,000$1.80M0.09%+50,000+3.3%Added
Renaissance Technologies LLC1,529,553$1.77M0.00%+703,512+85.2%Added
Tybourne Capital Management (HK) Ltd1,478,152$1.71M4.96%+516,666+53.7%Added
Decheng Capital LLC1,323,327$1.54M0.39%−696,435−34.5%Reduced
Two Sigma Advisers, LP1,275,914$1.48M0.00%+433,314+51.4%Added
D. E. Shaw & Co., Inc.1,197,624$1.39M0.00%+79,847+7.1%Added
Gsa Capital Partners LLP1,133,375$1.31M0.09%+591,400+109.1%Added
Morgan Stanley1,097,651$1.27M0.00%+3,693+0.3%Added
Two Sigma Investments, LP1,093,053$1.27M0.00%+543,719+99.0%Added
Primecap Management Co1,027,620$1.19M0.00%−237,000−18.7%Reduced
Balyasny Asset Management LLC970,862$1.13M0.00%+970,862New
Pfizer Inc953,834$1.11M0.19%00.0%Unchanged
Goldman Sachs Group Inc861,767$999.6K0.00%+405,374+88.8%Added
Jacobs Levy Equity Management, Inc857,582$994.8K0.00%+508,617+145.8%Added
Bank of America Corp713,315$827.4K0.00%−416,777−36.9%Reduced
Jane Street Group, LLC664,061$770.3K0.00%+515,257+346.3%Added
Geode Capital Management, LLC618,167$717.4K0.00%−737,502−54.4%Reduced
Peapod Lane Capital LLC559,213$648.7K0.65%+795+0.1%Added
JPMorgan Chase & Co550,447$638.5K0.00%−196,029−26.3%Reduced
Woodline Partners LP530,582$615.5K0.00%00.0%Unchanged
5AM Venture Management, LLC490,000$568.4K0.22%00.0%Unchanged
Citadel Advisors LLC462,340$536.3K0.00%+391,282+550.7%Added
AQR Capital Management LLC434,958$504.6K0.00%−184,372−29.8%Reduced
Man Group plc406,344$471.4K0.00%+305,328+302.3%Added
Dimensional Fund Advisors LP335,966$389.7K0.00%−111,434−24.9%Reduced
Cubist Systematic Strategies, LLC320,318$371.6K0.00%+242,106+309.6%Added
Connor, Clark & Lunn Investment Management Ltd.314,845$365.2K0.00%−46,391−12.8%Reduced
Charles Schwab Investment Management Inc299,097$347.0K0.00%−187,402−38.5%Reduced
State Street Corp271,790$315.3K0.00%−1,047,995−79.4%Reduced
XTX Topco Ltd264,829$307.2K0.01%+140,433+112.9%Added
Wealth Enhancement Advisory Services, LLC174,006$219.2K0.00%−60,065−25.7%Reduced
FMR LLC184,677$214.2K0.00%+2,487+1.4%Added
BNP Paribas Arbitrage, SA173,484$201.2K0.00%+102,661+145.0%Added
SEI Investments Co167,100$193.8K0.00%−35,320−17.4%Reduced
Invesco Ltd.155,714$180.6K0.00%+6,230+4.2%Added
Russell Investments Group, Ltd.150,990$175.1K0.00%−1,265−0.8%Reduced
Susquehanna International Group, LLP145,769$169.1K0.00%+40,082+37.9%Added
Walleye Capital LLC129,867$150.6K0.00%−211,521−62.0%Reduced
UBS Group AG129,468$150.2K0.00%−12,468−8.8%Reduced
Northern Trust Corp123,444$143.2K0.00%−338,859−73.3%Reduced
HRT Financial LP113,863$132.0K0.00%+113,863New
Stonepine Capital Management, LLC109,010$126.5K0.12%+49,010+81.7%Added
Quarry LP105,000$121.8K0.03%−15,000−12.5%Reduced
Ameriprise Financial Inc91,195$105.8K0.00%+78,578+622.8%Added
Ieq Capital, LLC86,300$100.1K0.00%−7,620−8.1%Reduced
RBF Capital, LLC80,000$92.8K0.00%+80,000New
Bridgeway Capital Management, LLC77,300$89.7K0.00%−75,000−49.2%Reduced
State of Wyoming73,797$85.6K0.01%+28,621+63.4%Added
Jain Global LLC72,261$83.8K0.00%+72,261New
Anfield Capital Management, LLC71,377$82.8K0.03%00.0%Unchanged
Thrivent Financial for Lutherans70,641$82.0K0.00%00.0%Unchanged
Commonwealth Equity Services, LLC60,987$71.0K0.00%+300+0.5%Added
Point72 Asia (Singapore) Pte. Ltd.59,453$69.0K0.01%+41,348+228.4%Added
Quadrature Capital Ltd52,456$60.6K0.00%+52,456New
Universal- Beteiligungs- und Servicegesellschaft mbH51,061$59.2K0.00%00.0%Unchanged
ADAR1 Capital Management, LLC50,000$58.0K0.01%+50,000New
Squarepoint Ops LLC46,461$53.9K0.00%−2,641−5.4%Reduced
Price T Rowe Associates Inc41,454$49.0K0.00%−28,231−40.5%Reduced
Barr E S & Co40,000$46.4K0.00%00.0%Unchanged
Federated Hermes, Inc.39,736$46.1K0.00%−712,781−94.7%Reduced
Public Employees Retirement System of Ohio36,700$42.6K0.00%+28,576+351.7%Added
CI Private Wealth, LLC35,760$41.5K0.00%+35,760New
Graham Capital Management, L.P.35,475$41.2K0.00%−89,326−71.6%Reduced
Tudor Investment Corp Et Al34,849$40.4K0.00%00.0%Unchanged
Y-Intercept (Hong Kong) Ltd32,740$38.0K0.00%+32,740New
Qube Research & Technologies Ltd32,113$37.3K0.00%+32,113New
Creative Planning30,340$35.2K0.00%−206,183−87.2%Reduced
Carson Advisory Inc.29,570$34.3K0.02%00.0%Unchanged
Regency Capital Management Inc.29,500$34.2K0.02%00.0%Unchanged
HSBC Holdings PLC27,877$33.3K0.00%+27,877New
CWM, LLC28,646$33.0K0.00%−11,053−27.8%Reduced
Catalyst Funds Management Pty Ltd26,800$31.1K0.01%+26,800New
Harvest Investment Services, LLC25,472$29.5K0.01%+705+2.8%Added
SG Americas Securities, LLC23,343$27.0K0.00%−761−3.2%Reduced
49 Wealth Management, LLC21,546$25.0K0.00%−23,967−52.7%Reduced
Raymond James Financial Inc20,595$23.9K0.00%−1,670−7.5%Reduced
Acorn Wealth Advisors, LLC20,000$23.2K0.01%+20,000New
Citigroup Inc19,447$22.6K0.00%−21,199−52.2%Reduced
Prudential Financial Inc18,900$21.9K0.00%−13,070−40.9%Reduced
Tower Research Capital LLC (TRC)17,114$19.9K0.00%+11,873+226.5%Added
Birchview Capital, LP17,000$19.7K0.02%00.0%Unchanged
Evergreen Capital Management LLC16,915$19.6K0.00%00.0%Unchanged
DRW Securities, LLC16,830$19.5K0.00%+16,830New
Hudson Bay Capital Management LP16,638$19.3K0.00%+16,638New
Engineers Gate Manager LP13,021$15.1K0.00%+13,021New
Captrust Financial Advisors11,842$13.7K0.00%−4,103−25.7%Reduced
Jump Financial, LLC11,692$13.6K0.00%+11,692New
R Squared Ltd10,808$12.5K0.01%+10,808New
Dynamic Technology Lab Private Ltd10,546$12.0K0.00%−9,210−46.6%Reduced
Simplex Trading, LLC9,699$11.0K0.00%+8,154+527.8%Added
Highline Wealth Partners LLC7,000$8.12K0.00%+7,000New
Caitong International Asset Management Co., Ltd2,713$3.15K0.00%+2,704+30,044.4%Added
EverSource Wealth Advisors, LLC2,350$2.73K0.00%−127−5.1%Reduced