Zentalis Pharmaceuticals, Inc.
ZNTL- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001725160
In the last 90 days, Zentalis Pharmaceuticals, Inc. insiders filed 1 open-market purchase and 0 sales; 114 institutions reported holding it in 13F filings for Q2 2026, worth $228.9M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Zentalis Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 86
- −10 vs. Q3 2025
- Shares held
- 40.6M
- −11.1M (−21.5%) vs. Q3 2025
- Total value
- $54.9M
- −$23.2M (−29.7%) vs. Q3 2025
- New holders
- 8
- 28 more added
- Sold out
- 18
- 30 more reduced
3 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ZNTL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 114 | $228.9M |
| Q1 2026 | 102 | $101.7M |
| Q4 2025 | 86 | $54.9M |
| Q3 2025 | 99 | $79.7M |
| Q2 2025 | 117 | $64.5M |
| Q1 2025 | 132 | $92.9M |
| Q4 2024 | 142 | $195.2M |
| Q3 2024 | 136 | $261.2M |
| Q2 2024 | 145 | $314.3M |
| Q1 2024 | 142 | $1.34B |
| Q4 2023 | 120 | $1.23B |
| Q3 2023 | 137 | $1.61B |
| Q2 2023 | 134 | $2.32B |
| Q1 2023 | 110 | $1.15B |
| Q4 2022 | 106 | $1.30B |
| Q3 2022 | 121 | $1.27B |
| Q2 2022 | 122 | $1.64B |
| Q1 2022 | 128 | $2.05B |
| Q4 2021 | 139 | $3.61B |
| Q3 2021 | 116 | $2.75B |
| Q2 2021 | 120 | $2.13B |
| Q1 2021 | 95 | $1.58B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Zentalis Pharmaceuticals, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 51 | $0 | 0.00% | −1−1.9% | Reduced |
| Caitong International Asset Management Co., Ltd | 1 | $1 | 0.00% | 00.0% | Unchanged |
| CWM Advisors, LLC | 16 | $22 | 0.00% | +16 | New |
| SBI Securities Co., Ltd. | 27 | $36 | 0.00% | −1−3.6% | Reduced |
| Optiver Holding B.V. | 44 | $59 | 0.00% | 00.0% | Unchanged |
| HighMark Wealth Management LLC | 130 | $175 | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 387 | $522 | 0.00% | 00.0% | Unchanged |
| Bryn Mawr Trust Co | 1,000 | $1.35K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 1,644 | $2.22K | 0.00% | −949−36.6% | Reduced |
| Highline Wealth Partners LLC | 5,000 | $6.75K | 0.00% | −7,000−58.3% | Reduced |
| CWM, LLC | 8,564 | $12.0K | 0.00% | −4,554−34.7% | Reduced |
| Susquehanna International Group, LLP | 10,343 | $14.0K | 0.00% | −190,766−94.9% | Reduced |
| Shay Capital LLC | 10,662 | $14.4K | 0.00% | +10,662 | New |
| Ieq Capital, LLC | 12,229 | $16.5K | 0.00% | −21,924−64.2% | Reduced |
| Royal Bank of Canada | 12,740 | $17.0K | 0.00% | +12,318+2,919.0% | Added |
| American Century Companies Inc | 12,880 | $17.4K | 0.00% | +12,880 | New |
| Evergreen Capital Management LLC | 16,915 | $22.8K | 0.00% | 00.0% | Unchanged |
| Birchview Capital, LP | 17,000 | $22.9K | 0.01% | 00.0% | Unchanged |
| Qube Research & Technologies Ltd | 17,471 | $23.6K | 0.00% | −39,168−69.2% | Reduced |
| Raymond James Financial Inc | 19,895 | $26.9K | 0.00% | −700−3.4% | Reduced |
| Acorn Wealth Advisors, LLC | 20,000 | $27.0K | 0.01% | 00.0% | Unchanged |
| Sivia Capital Partners, LLC | 20,000 | $27.0K | 0.01% | +20,000 | New |
| Carson Advisory Inc. | 23,470 | $31.7K | 0.02% | −8,600−26.8% | Reduced |
| Prudential Financial Inc | 24,550 | $33.1K | 0.00% | +2,950+13.7% | Added |
| Regency Capital Management Inc. | 29,500 | $39.8K | 0.02% | 00.0% | Unchanged |
| Federated Hermes, Inc. | 34,574 | $46.7K | 0.00% | −6,545−15.9% | Reduced |
| Tudor Investment Corp Et Al | 34,849 | $47.0K | 0.00% | 00.0% | Unchanged |
| AQR Capital Management LLC | 45,995 | $62.1K | 0.00% | −60,970−57.0% | Reduced |
| Algert Global LLC | 48,496 | $65.5K | 0.00% | 00.0% | Unchanged |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 51,061 | $68.9K | 0.00% | 00.0% | Unchanged |
| Barr E S & Co | 57,500 | $77.6K | 0.00% | +17,500+43.8% | Added |
| Commonwealth Equity Services, LLC | 61,412 | $82.9K | 0.00% | +425+0.7% | Added |
| 49 Wealth Management, LLC | 70,911 | $95.7K | 0.01% | +42,719+151.5% | Added |
| Bridgeway Capital Management, LLC | 77,300 | $104.4K | 0.00% | 00.0% | Unchanged |
| RBF Capital, LLC | 80,000 | $108.0K | 0.00% | 00.0% | Unchanged |
| ADAR1 Capital Management, LLC | 80,000 | $108.0K | 0.01% | +30,000+60.0% | Added |
| Panagora Asset Management Inc | 86,640 | $117.0K | 0.00% | −11,258−11.5% | Reduced |
| Graham Capital Management, L.P. | 90,910 | $122.7K | 0.00% | −61,237−40.2% | Reduced |
| Northern Trust Corp | 92,871 | $125.4K | 0.00% | −1,248−1.3% | Reduced |
| Dimensional Fund Advisors LP | 96,263 | $129.9K | 0.00% | −88,769−48.0% | Reduced |
| Point72 Asset Management, L.P. | 100,290 | $135.4K | 0.00% | +100,290 | New |
| Squarepoint Ops LLC | 107,734 | $145.4K | 0.00% | +86,412+405.3% | Added |
| Walleye Capital LLC | 110,448 | $149.1K | 0.00% | −10,000−8.3% | Reduced |
| Goldman Sachs Group Inc | 118,212 | $159.6K | 0.00% | −226,943−65.8% | Reduced |
| Jacobs Levy Equity Management, Inc | 124,525 | $168.1K | 0.00% | −576,051−82.2% | Reduced |
| Opal Capital LLC | 72,251 | $173.4K | 0.04% | +72,251 | New |
| Quarry LP | 132,000 | $178.2K | 0.03% | +23,250+21.4% | Added |
| Quadrature Capital Ltd | 137,568 | $185.7K | 0.00% | +76,917+126.8% | Added |
| SEI Investments Co | 167,100 | $225.6K | 0.00% | 00.0% | Unchanged |
| Wealth Enhancement Advisory Services, LLC | 130,407 | $232.1K | 0.00% | −35,883−21.6% | Reduced |
| JPMorgan Chase & Co | 185,007 | $249.8K | 0.00% | −538,068−74.4% | Reduced |
| Invesco Ltd. | 188,582 | $254.6K | 0.00% | +14,961+8.6% | Added |
| Anfield Capital Management, LLC | 242,605 | $327.5K | 0.10% | +171,228+239.9% | Added |
| FMR LLC | 243,308 | $328.5K | 0.00% | +40,003+19.7% | Added |
| Marshall Wace, LLP | 247,788 | $334.5K | 0.00% | +247,788 | New |
| Creative Planning | 260,000 | $351.0K | 0.00% | 00.0% | Unchanged |
| State Street Corp | 271,790 | $366.9K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 419,367 | $566.1K | 0.00% | +260,432+163.9% | Added |
| Peapod Lane Capital LLC | 448,861 | $606.0K | 0.52% | −116,510−20.6% | Reduced |
| Stonepine Capital Management, LLC | 463,700 | $626.0K | 0.50% | +9,900+2.2% | Added |
| Jane Street Group, LLC | 473,175 | $638.8K | 0.00% | −172,448−26.7% | Reduced |
| Woodline Partners LP | 530,582 | $716.3K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 568,443 | $767.4K | 0.00% | +406,973+252.0% | Added |
| XTX Topco Ltd | 576,707 | $778.6K | 0.02% | +28,078+5.1% | Added |
| Geode Capital Management, LLC | 589,105 | $795.7K | 0.00% | −1170.0% | Reduced |
| Almitas Capital LLC | 610,073 | $823.6K | 0.18% | +152,751+33.4% | Added |
| Millennium Management LLC | 673,129 | $908.7K | 0.00% | −229,392−25.4% | Reduced |
| UBS Group AG | 674,598 | $910.7K | 0.00% | +141,920+26.6% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 787,055 | $1.06M | 0.00% | +406,233+106.7% | Added |
| Morgan Stanley | 803,654 | $1.08M | 0.00% | −604,175−42.9% | Reduced |
| Pfizer Inc | 953,834 | $1.29M | 0.54% | 00.0% | Unchanged |
| Primecap Management Co | 957,420 | $1.29M | 0.00% | −5,200−0.5% | Reduced |
| Gsa Capital Partners LLP | 1,169,573 | $1.58M | 0.14% | +91,917+8.5% | Added |
| BlackRock, Inc. | 1,249,968 | $1.69M | 0.00% | +4640.0% | Added |
| Ishara Investments LP | 1,320,000 | $1.78M | 2.07% | +1,320,000 | New |
| Decheng Capital LLC | 1,323,327 | $1.79M | 0.24% | 00.0% | Unchanged |
| Bank of America Corp | 1,367,254 | $1.85M | 0.00% | −181,527−11.7% | Reduced |
| Opaleye Management Inc. | 1,400,906 | $1.89M | 0.25% | +1,084,356+342.6% | Added |
| Two Sigma Investments, LP | 1,471,414 | $1.99M | 0.00% | +108,067+7.9% | Added |
| Two Sigma Advisers, LP | 1,483,500 | $2.00M | 0.00% | +22,300+1.5% | Added |
| D. E. Shaw & Co., Inc. | 1,660,378 | $2.24M | 0.00% | +251,575+17.9% | Added |
| Citadel Advisors LLC | 1,964,255 | $2.65M | 0.00% | −113,035−5.4% | Reduced |
| Acadian Asset Management LLC | 2,849,294 | $3.84M | 0.01% | +4,142+0.1% | Added |
| Vanguard Group Inc | 2,855,590 | $3.86M | 0.00% | −48,810−1.7% | Reduced |
| Renaissance Technologies LLC | 2,883,745 | $3.89M | 0.01% | +558,390+24.0% | Added |
| 5AM Venture Management, LLC | 3,947,913 | $5.33M | 1.68% | +3,457,913+705.7% | Added |
| Matrix Capital Management Company, LP | 0 | $0 | 0.00% | −13,959,973−100.0% | Sold out |
| Tang Capital Management LLC | 0 | $0 | 0.00% | −1,550,000−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −1,185,521−100.0% | Sold out |
| Ameriprise Financial Inc | 0 | $0 | 0.00% | −52,572−100.0% | Sold out |
| Catalyst Funds Management Pty Ltd | 0 | $0 | 0.00% | −51,400−100.0% | Sold out |
| Charles Schwab Investment Management Inc | 0 | $0 | 0.00% | −41,981−100.0% | Sold out |
| Public Employees Retirement System of Ohio | 0 | $0 | 0.00% | −31,900−100.0% | Sold out |
| SG Americas Securities, LLC | 0 | $0 | 0.00% | −31,579−100.0% | Sold out |
| Bluefin Capital Management, LLC | 0 | $0 | 0.00% | −31,266−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −30,424−100.0% | Sold out |
| Tower Research Capital LLC (TRC) | 0 | $0 | 0.00% | −29,386−100.0% | Sold out |
| Voleon Capital Management LP | 0 | $0 | 0.00% | −27,161−100.0% | Sold out |
| Harvest Investment Services, LLC | 0 | $0 | 0.00% | −14,206−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −13,619−100.0% | Sold out |