Xilio Therapeutics, Inc.
XLO- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001840233
No open-market purchases or sales by Xilio Therapeutics, Inc. insiders were filed in the last 90 days; 27 institutions reported holding it in 13F filings for Q2 2026, worth $32.6M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Xilio Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 24
- −12 vs. Q4 2025
- Shares held
- 2.62M
- −128.5K (−4.7%) vs. Q4 2025Converted for a 1-for-14 split
- Total value
- $22.0M
- −$2.60M (−10.6%) vs. Q4 2025
- New holders
- 7
- 7 more added
- Sold out
- 19
- 2 more reduced
1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XLO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 27 | $32.6M |
| Q1 2026 | 24 | $22.0M |
| Q4 2025 | 37 | $25.4M |
| Q3 2025 | 36 | $18.6M |
| Q2 2025 | 35 | $16.2M |
| Q1 2025 | 35 | $16.3M |
| Q4 2024 | 35 | $24.7M |
| Q3 2024 | 33 | $12.6M |
| Q2 2024 | 32 | $13.7M |
| Q1 2024 | 31 | $13.5M |
| Q4 2023 | 34 | $9.03M |
| Q3 2023 | 31 | $33.5M |
| Q2 2023 | 32 | $41.9M |
| Q1 2023 | 32 | $51.0M |
| Q4 2022 | 28 | $42.8M |
| Q3 2022 | 29 | $48.3M |
| Q2 2022 | 33 | $52.2M |
| Q1 2022 | 41 | $132.7M |
| Q4 2021 | 42 | $303.1M |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Xilio Therapeutics, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Key Financial Inc | 59 | $496 | 0.00% | 00.0% | UnchangedConverted for a 1-for-14 split |
| Royal Bank of Canada | 91 | $1.00K | 0.00% | +91 | New |
| Vanguard Global Advisers, LLC | 210 | $1.77K | 0.00% | +210 | New |
| JPMorgan Chase & Co | 240 | $1.98K | 0.00% | +240 | New |
| UBS Group AG | 4,038 | $34.0K | 0.00% | +4,023+27,748.3% | AddedConverted for a 1-for-14 split |
| CWM, LLC | 4,206 | $35.4K | 0.00% | +4,206 | New |
| State Street Corp | 13,311 | $111.9K | 0.00% | 00.0% | UnchangedConverted for a 1-for-14 split |
| Ghisallo Capital Management LLC | 13,800 | $116.1K | 0.00% | −65,716−82.6% | ReducedConverted for a 1-for-14 split |
| Velan Capital Investment Management LP | 14,285 | $120.1K | 0.08% | +2,142+17.6% | AddedConverted for a 1-for-14 split |
| Gsa Capital Partners LLP | 16,946 | $143.0K | 0.01% | +6,377+60.3% | AddedConverted for a 1-for-14 split |
| Vanguard Fiduciary Trust Co | 28,475 | $239.5K | 0.00% | +28,475 | New |
| FMR LLC | 36,558 | $307.5K | 0.00% | 00.0% | UnchangedConverted for a 1-for-14 split |
| Geode Capital Management, LLC | 37,197 | $312.8K | 0.00% | +13,699+58.3% | AddedConverted for a 1-for-14 split |
| AJU IB Investment Co., Ltd. | 47,695 | $401.1K | 1.31% | 00.0% | UnchangedConverted for a 1-for-14 split |
| Renaissance Technologies LLC | 49,566 | $416.9K | 0.00% | +24,965+101.5% | AddedConverted for a 1-for-14 split |
| Morgan Stanley | 57,493 | $483.5K | 0.00% | −2,496−4.2% | ReducedConverted for a 1-for-14 split |
| Stonepine Capital Management, LLC | 64,162 | $539.6K | 0.47% | +55,143+611.4% | AddedConverted for a 1-for-14 split |
| Merck & Co., Inc. | 105,982 | $891.3K | 0.26% | 00.0% | UnchangedConverted for a 1-for-14 split |
| Caligan Partners LP | 112,128 | $943.0K | 0.07% | +112,128 | New |
| Vanguard Capital Management LLC | 123,660 | $1.04M | 0.00% | +123,660 | New |
| Sio Capital Management, LLC | 152,464 | $1.28M | 0.18% | 00.0% | UnchangedConverted for a 1-for-14 split |
| Frazier Life Sciences Management, L.P. | 422,505 | $3.55M | 0.09% | 00.0% | UnchangedConverted for a 1-for-14 split |
| Gilead Sciences, Inc. | 650,389 | $5.47M | 0.26% | 00.0% | UnchangedConverted for a 1-for-14 split |
| Bain Capital Life Sciences Investors, LLC | 664,021 | $5.58M | 0.50% | +137,401+26.1% | AddedConverted for a 1-for-14 split |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −285,714−100.0% | Sold outConverted for a 1-for-14 split |
| StemPoint Capital LP | 0 | $0 | 0.00% | −145,002−100.0% | Sold outConverted for a 1-for-14 split |
| Empery Asset Management, LP | 0 | $0 | 0.00% | −84,503−100.0% | Sold outConverted for a 1-for-14 split |
| Citadel Advisors LLC | 0 | $0 | 0.00% | −31,158−100.0% | Sold outConverted for a 1-for-14 split |
| Northern Trust Corp | 0 | $0 | 0.00% | −4,758−100.0% | Sold outConverted for a 1-for-14 split |
| Two Sigma Investments, LP | 0 | $0 | 0.00% | −4,431−100.0% | Sold outConverted for a 1-for-14 split |
| Bridgeway Capital Management, LLC | 0 | $0 | 0.00% | −4,006−100.0% | Sold outConverted for a 1-for-14 split |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −3,006−100.0% | Sold outConverted for a 1-for-14 split |
| HRT Financial LP | 0 | $0 | 0.00% | −2,278−100.0% | Sold outConverted for a 1-for-14 split |
| Mariner, LLC | 0 | $0 | 0.00% | −1,786−100.0% | Sold outConverted for a 1-for-14 split |
| LPL Financial LLC | 0 | $0 | 0.00% | −1,500−100.0% | Sold outConverted for a 1-for-14 split |
| Raymond James Financial Inc | 0 | $0 | 0.00% | −1,340−100.0% | Sold outConverted for a 1-for-14 split |
| XTX Topco Ltd | 0 | $0 | 0.00% | −1,236−100.0% | Sold outConverted for a 1-for-14 split |
| Dunhill Financial, LLC | 0 | $0 | 0.00% | −734−100.0% | Sold outConverted for a 1-for-14 split |
| Investors Asset Management of Georgia Inc | 0 | $0 | 0.00% | −714−100.0% | Sold outConverted for a 1-for-14 split |
| Pinnacle Financial Group, LLC | 0 | $0 | 0.00% | −714−100.0% | Sold outConverted for a 1-for-14 split |
| BlackRock, Inc. | 0 | $0 | 0.00% | −146−100.0% | Sold outConverted for a 1-for-14 split |
| Private Wealth Management Group, LLC | 0 | $0 | 0.00% | −22−100.0% | Sold outConverted for a 1-for-14 split |
| Bank of America Corp | 0 | $0 | 0.00% | −19−100.0% | Sold outConverted for a 1-for-14 split |
| Vanguard Group Inc | – | – | – | – | Not filed |