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Livermore
Livermore
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Xilio Therapeutics, Inc.

XLO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001840233

No open-market purchases or sales by Xilio Therapeutics, Inc. insiders were filed in the last 90 days; 27 institutions reported holding it in 13F filings for Q2 2026, worth $32.6M in total; no superinvestor holds it.

Holders of 5% or more of XLO

Holders whose latest Schedule 13D or 13G filing reports 5% or more of Xilio Therapeutics, Inc., largest stake first. The change is against the holder's previous filing.

Holders of 5% or more of XLO
HolderLatest formStakeChangeFirst filedLatest filingFiling
Gilead Sciences, Inc.13G/A19.90%14.5M shares0.00 ppfrom 19.90%Dec 19, 20243 filingsFeb 12, 2026SEC
Coastlands Capital LP13G9.99%5.35M sharesNewDec 11, 20251 filingDec 11, 2025SEC
Bain Capital Life Sciences Fund II, L.P.13G/A9.99%664.0K shares–May 15, 20261 filingMay 15, 2026SEC
OrbiMed Advisors LLC13G9.99%642.0K sharesNewMay 15, 20261 filingMay 15, 2026SEC
Sirenia Capital Management LP13G9.90%1.14M sharesNewMay 15, 20261 filingMay 15, 2026SEC
AbbVie Inc.13G9.00%4.35M sharesNewFeb 18, 20251 filingFeb 18, 2025SEC
Bain Capital Life Sciences Fund II, L.P.13G/A8.50%6.26M shares–Feb 17, 20261 filingFeb 17, 2026SEC
StemPoint Capital LP13G/A8.40%6.03M shares+1.20 ppfrom 7.20%Nov 14, 20252 filingsFeb 17, 2026SEC
Frazier Life Sciences Public Fund, L.P.13G/A6.70%4.68M shares−3.20 ppfrom 9.90%Jun 12, 20253 filingsFeb 13, 2026SEC

Stakes are as of each holder's latest filing. Holders whose last filing was in the old format (before December 18, 2024) have no stake on record and are not listed, and after an acquisition or delisting holders usually stop filing.

13D and 13G filings

18 Schedule 13D and 13G filings on Xilio Therapeutics, Inc., newest first, including old-format filings without a stake.

Schedule 13D and 13G filings on XLO
Filed (ET)FilerFormStakeChangeEvent dateFiling
May 15, 20264:38 PM ETOrbiMed Advisors LLCand 1 other13G9.99%642.0K sharesNewMar 31, 2026SEC
May 15, 20264:30 PM ETBain Capital Life Sciences Fund II, L.P.and 2 others13G/A9.99%664.0K shares–Mar 31, 2026SEC
May 15, 20264:24 PM ETPoint72 Asset Management, L.P.and 2 others13G/A0.00%0 shares−9.90 ppfrom 9.90%Below 5%Mar 31, 2026SEC
May 15, 20268:06 AM ETSirenia Capital Management LPand 1 other13G9.90%1.14M sharesNewMar 31, 2026SEC
Feb 17, 20264:30 PM ETBain Capital Life Sciences Fund II, L.P.and 3 others13G/A8.50%6.26M shares–Dec 31, 2025SEC
Feb 17, 202610:00 AM ETStemPoint Capital LPand 2 others13G/A8.40%6.03M shares+1.20 ppfrom 7.20%Dec 31, 2025SEC
Feb 13, 20265:31 PM ETFrazier Life Sciences Public Fund, L.P.and 13 others13G/A6.70%4.68M shares−3.20 ppfrom 9.90%Dec 31, 2025SEC
Feb 12, 20264:39 PM ETGilead Sciences, Inc.13G/A19.90%14.5M shares0.00 ppfrom 19.90%Dec 31, 2025SEC
Dec 11, 20255:55 PM ETCoastlands Capital LPand 4 others13G9.99%5.35M sharesNewDec 4, 2025SEC
Nov 14, 20254:02 PM ETPoint72 Asset Management, L.P.and 2 others13G/A9.90%8.00M shares+2.70 ppfrom 7.20%Sep 30, 2025SEC
Nov 14, 202510:00 AM ETStemPoint Capital LPand 2 others13G7.20%4.00M sharesNewSep 30, 2025SEC
Aug 14, 20254:42 PM ETGilead Sciences, Inc.13G/A19.90%10.6M shares0.00 ppfrom 19.90%Jun 30, 2025SEC
Aug 14, 20251:47 PM ETFrazier Life Sciences Public Fund, L.P.and 19 others13G/A9.90%8.14M shares0.00 ppfrom 9.90%Jun 30, 2025SEC
Jun 17, 20255:28 PM ETPoint72 Asset Management, L.P.and 2 others13G7.20%4.00M sharesNewJun 5, 2025SEC
Jun 12, 20254:55 PM ETFrazier Life Sciences Public Fund, L.P.and 19 others13G9.90%5.75M sharesNewJun 5, 2025SEC
May 15, 202510:48 AM ETRock Springs Capital Management LPand 4 others13G/A0.00%0 shares–Below 5%Mar 31, 2025SEC
Feb 18, 20254:15 PM ETAbbVie Inc.13G9.00%4.35M sharesNewFeb 11, 2025SEC
Dec 19, 20244:15 PM ETGilead Sciences, Inc.13G/A19.90%9.11M shares–Dec 18, 2024SEC

Form 144: proposed insider sales

Notices from officers, directors and other affiliates planning to sell Xilio Therapeutics, Inc. shares.

No Form 144 notices for Xilio Therapeutics, Inc. are on file.