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Xilio Therapeutics, Inc.

XLO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001840233

No open-market purchases or sales by Xilio Therapeutics, Inc. insiders were filed in the last 90 days; 27 institutions reported holding it in 13F filings for Q2 2026, worth $32.6M in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Xilio Therapeutics, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
35
+4 vs. Q3 2024
Shares held
25.9M
+11.4M (+78.6%) vs. Q3 2024
Total value
$24.7M
+$13.3M (+116.3%) vs. Q3 2024
New holders
9
6 more added
Sold out
5
6 more reduced

2 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XLO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 35 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 42 institutionsQ1 2022: 41 institutionsQ2 2022: 33 institutionsQ3 2022: 29 institutionsQ4 2022: 28 institutionsQ1 2023: 32 institutionsQ2 2023: 32 institutionsQ3 2023: 31 institutionsQ4 2023: 34 institutionsQ1 2024: 31 institutionsQ2 2024: 32 institutionsQ3 2024: 33 institutionsQ4 2024: 35 institutionsQ1 2025: 35 institutionsQ2 2025: 35 institutionsQ3 2025: 36 institutionsQ4 2025: 37 institutionsQ1 2026: 24 institutionsQ2 2026: 27 institutions
Value heldQ4 2024: $24.7M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $303.1MQ1 2022: $132.7MQ2 2022: $52.2MQ3 2022: $48.3MQ4 2022: $42.8MQ1 2023: $51.0MQ2 2023: $41.9MQ3 2023: $33.5MQ4 2023: $9.03MQ1 2024: $13.5MQ2 2024: $13.7MQ3 2024: $12.6MQ4 2024: $24.7MQ1 2025: $16.3MQ2 2025: $16.2MQ3 2025: $18.6MQ4 2025: $25.4MQ1 2026: $22.0MQ2 2026: $32.6M
Institutions holding XLO and their total value by quarter
QuarterHoldersValue
Q2 202627$32.6M
Q1 202624$22.0M
Q4 202537$25.4M
Q3 202536$18.6M
Q2 202535$16.2M
Q1 202535$16.3M
Q4 202435$24.7M
Q3 202433$12.6M
Q2 202432$13.7M
Q1 202431$13.5M
Q4 202334$9.03M
Q3 202331$33.5M
Q2 202332$41.9M
Q1 202332$51.0M
Q4 202228$42.8M
Q3 202229$48.3M
Q2 202233$52.2M
Q1 202241$132.7M
Q4 202142$303.1M
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Xilio Therapeutics, Inc.; share changes are against Q3 2024.

Institutions holding XLO in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Gilead Sciences, Inc.9,105,451$8.70M0.56%+9,105,451New
Bain Capital Life Sciences Investors, LLC4,566,817$4.36M0.51%00.0%Unchanged
Rock Springs Capital Management LP3,003,259$2.87M0.11%00.0%Unchanged
Merck & Co., Inc.1,483,758$1.42M0.55%+1,483,758New
Takeda Pharmaceutical Co Ltd1,475,121$1.42M5.33%00.0%Unchanged
FMR LLC1,395,853$1.33M0.00%00.0%Unchanged
Morgan Stanley1,001,359$956.3K0.00%−520,743−34.2%Reduced
Vanguard Group Inc902,531$861.9K0.00%00.0%Unchanged
AJU IB Investment Co., Ltd.667,742$637.7K0.62%+667,742New
Geode Capital Management, LLC358,422$342.3K0.00%+20,230+6.0%Added
Balyasny Asset Management LLC343,230$327.8K0.00%+70,744+26.0%Added
Renaissance Technologies LLC296,617$283.3K0.00%+30,317+11.4%Added
Trustees of Columbia University in the City of New York249,635$238.4K0.04%+249,635New
UBS Group AG249,401$238.2K0.00%+233,668+1,485.2%Added
FIL Ltd218,705$208.9K0.00%00.0%Unchanged
BlackRock, Inc.76,086$72.7K0.00%+462+0.6%Added
Bridgeway Capital Management, LLC71,081$67.9K0.00%00.0%Unchanged
Raymond James Financial Inc50,086$47.8K0.00%+50,086New
Susquehanna International Group, LLP49,093$46.9K0.00%+49,093New
State Street Corp43,390$41.4K0.00%00.0%Unchanged
Aptus Capital Advisors, LLC41,000$39.2K0.00%+41,000New
Citadel Advisors LLC40,316$38.5K0.00%+40,316New
Northern Trust Corp39,208$37.4K0.00%00.0%Unchanged
SevenBridge Financial Group, LLC41,000$26.9K0.01%00.0%Unchanged
Mariner, LLC25,000$23.9K0.00%−317−1.3%Reduced
Steward Partners Investment Advisory, LLC20,000$19.1K0.00%00.0%Unchanged
XTX Topco Ltd12,870$12.3K0.00%−10,992−46.1%Reduced
Two Sigma Investments, LP10,824$10.3K0.00%+435+4.2%Added
Pinnacle Financial Group, LLC10,000$9.55K0.00%00.0%Unchanged
Federation des caisses Desjardins du Quebec3,300$3.15K0.00%+3,300New
Tower Research Capital LLC (TRC)2,729$2.61K0.00%−2,887−51.4%Reduced
Key Financial Inc830$7930.00%00.0%Unchanged
Private Wealth Management Group, LLC310$2970.00%00.0%Unchanged
Bank of America Corp265$2530.00%−1−0.4%Reduced
JPMorgan Chase & Co66$630.00%−9−12.0%Reduced
Two Sigma Securities, LLC0$00.00%−44,445−100.0%Sold out
Engineers Gate Manager LP0$00.00%−32,752−100.0%Sold out
Millennium Management LLC0$00.00%−20,655−100.0%Sold out
Avantax Planning Partners, Inc.0$00.00%−20,483−100.0%Sold out
Dunhill Financial, LLC0$00.00%−10,274−100.0%Sold out
RiverVest Venture Management LLC––––Not filed
Raymond James & Associates––––Not filed