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Xilio Therapeutics, Inc.

XLO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001840233

No open-market purchases or sales by Xilio Therapeutics, Inc. insiders were filed in the last 90 days; 27 institutions reported holding it in 13F filings for Q2 2026, worth $32.6M in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Xilio Therapeutics, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
35
0 vs. Q1 2025
Shares held
23.8M
+1.27M (+5.6%) vs. Q1 2025
Total value
$16.2M
−$139.5K (−0.9%) vs. Q1 2025
New holders
5
4 more added
Sold out
5
11 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XLO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 35 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 42 institutionsQ1 2022: 41 institutionsQ2 2022: 33 institutionsQ3 2022: 29 institutionsQ4 2022: 28 institutionsQ1 2023: 32 institutionsQ2 2023: 32 institutionsQ3 2023: 31 institutionsQ4 2023: 34 institutionsQ1 2024: 31 institutionsQ2 2024: 32 institutionsQ3 2024: 33 institutionsQ4 2024: 35 institutionsQ1 2025: 35 institutionsQ2 2025: 35 institutionsQ3 2025: 36 institutionsQ4 2025: 37 institutionsQ1 2026: 24 institutionsQ2 2026: 27 institutions
Value heldQ2 2025: $16.2M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $303.1MQ1 2022: $132.7MQ2 2022: $52.2MQ3 2022: $48.3MQ4 2022: $42.8MQ1 2023: $51.0MQ2 2023: $41.9MQ3 2023: $33.5MQ4 2023: $9.03MQ1 2024: $13.5MQ2 2024: $13.7MQ3 2024: $12.6MQ4 2024: $24.7MQ1 2025: $16.3MQ2 2025: $16.2MQ3 2025: $18.6MQ4 2025: $25.4MQ1 2026: $22.0MQ2 2026: $32.6M
Institutions holding XLO and their total value by quarter
QuarterHoldersValue
Q2 202627$32.6M
Q1 202624$22.0M
Q4 202537$25.4M
Q3 202536$18.6M
Q2 202535$16.2M
Q1 202535$16.3M
Q4 202435$24.7M
Q3 202433$12.6M
Q2 202432$13.7M
Q1 202431$13.5M
Q4 202334$9.03M
Q3 202331$33.5M
Q2 202332$41.9M
Q1 202332$51.0M
Q4 202228$42.8M
Q3 202229$48.3M
Q2 202233$52.2M
Q1 202241$132.7M
Q4 202142$303.1M
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Xilio Therapeutics, Inc.; share changes are against Q1 2025.

Institutions holding XLO in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Gilead Sciences, Inc.9,105,451$6.19M0.48%00.0%Unchanged
Bain Capital Life Sciences Investors, LLC4,566,817$3.10M0.39%00.0%Unchanged
Merck & Co., Inc.1,483,758$1.01M0.47%00.0%Unchanged
Takeda Pharmaceutical Co Ltd1,475,121$1.00M5.13%00.0%Unchanged
Morgan Stanley1,444,326$982.0K0.00%+288,488+25.0%Added
Ghisallo Capital Management LLC1,333,000$906.3K0.02%+1,333,000New
Vanguard Group Inc1,151,023$782.7K0.00%+15,307+1.3%Added
AJU IB Investment Co., Ltd.667,742$454.0K0.49%00.0%Unchanged
FMR LLC511,820$348.0K0.00%−372,215−42.1%Reduced
Geode Capital Management, LLC369,660$251.4K0.00%−9,356−2.5%Reduced
Trustees of Columbia University in the City of New York249,635$169.8K0.02%00.0%Unchanged
UBS Group AG239,969$163.2K0.00%+76,868+47.1%Added
Squarepoint Ops LLC235,456$160.1K0.00%+235,456New
Balyasny Asset Management LLC198,859$135.2K0.00%−55,487−21.8%Reduced
Renaissance Technologies LLC164,200$111.6K0.00%−13,500−7.6%Reduced
Avantax Planning Partners, Inc.142,338$96.8K0.00%−8,061−5.4%Reduced
Two Sigma Investments, LP78,032$53.1K0.00%−6,036−7.2%Reduced
Northern Trust Corp66,609$45.3K0.00%00.0%Unchanged
Bridgeway Capital Management, LLC56,081$38.1K0.00%−15,000−21.1%Reduced
State Street Corp43,390$29.5K0.00%00.0%Unchanged
XTX Topco Ltd34,721$23.6K0.00%+34,721New
LPL Financial LLC31,000$21.1K0.00%+31,000New
SevenBridge Financial Group, LLC25,000$17.5K0.00%−21,000−45.7%Reduced
Aptus Capital Advisors, LLC25,000$17.0K0.00%−21,000−45.7%Reduced
Mariner, LLC25,000$17.0K0.00%00.0%Unchanged
Raymond James Financial Inc18,761$12.8K0.00%−15,200−44.8%Reduced
Tower Research Capital LLC (TRC)15,412$10.5K0.00%+15,412New
Dunhill Financial, LLC10,274$6.99K0.00%00.0%Unchanged
Investors Asset Management of Georgia Inc10,000$6.80K0.00%00.0%Unchanged
Pinnacle Financial Group, LLC10,000$6.80K0.00%00.0%Unchanged
Federation des caisses Desjardins du Quebec3,300$2.24K0.00%00.0%Unchanged
BlackRock, Inc.2,037$1.39K0.00%−72,663−97.3%Reduced
Key Financial Inc830$5640.00%00.0%Unchanged
Bank of America Corp331$2250.00%+41+14.1%Added
Private Wealth Management Group, LLC310$2110.00%00.0%Unchanged
Millennium Management LLC0$00.00%−51,110−100.0%Sold out
Scientech Research LLC0$00.00%−42,546−100.0%Sold out
ADAR1 Capital Management, LLC0$00.00%−40,000−100.0%Sold out
Steward Partners Investment Advisory, LLC0$00.00%−20,000−100.0%Sold out
JPMorgan Chase & Co0$00.00%−62−100.0%Sold out