X4 Pharmaceuticals, Inc
XFOR- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001501697
In the last 90 days, X4 Pharmaceuticals, Inc insiders filed 0 open-market purchases and 3 sales; 89 institutions reported holding it in 13F filings for Q2 2026, worth $491.9M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in X4 Pharmaceuticals, Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 79
- +38 vs. Q3 2025
- Shares held
- 89.4M
- +73.3M (+453.5%) vs. Q3 2025
- Total value
- $357.7M
- +$302.5M (+547.4%) vs. Q3 2025
- New holders
- 42
- 17 more added
- Sold out
- 4
- 8 more reduced
1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XFOR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 89 | $491.9M |
| Q1 2026 | 84 | $407.0M |
| Q4 2025 | 79 | $357.7M |
| Q3 2025 | 42 | $55.3M |
| Q2 2025 | 52 | $5.33M |
| Q1 2025 | 94 | $23.6M |
| Q4 2024 | 90 | $73.3M |
| Q3 2024 | 98 | $67.4M |
| Q2 2024 | 99 | $60.7M |
| Q1 2024 | 98 | $147.1M |
| Q4 2023 | 93 | $87.1M |
| Q3 2023 | 91 | $122.6M |
| Q2 2023 | 96 | $219.2M |
| Q1 2023 | 59 | $53.7M |
| Q4 2022 | 54 | $60.2M |
| Q3 2022 | 59 | $74.0M |
| Q2 2022 | 51 | $16.6M |
| Q1 2022 | 56 | $30.7M |
| Q4 2021 | 52 | $40.4M |
| Q3 2021 | 52 | $85.7M |
| Q2 2021 | 63 | $111.5M |
| Q1 2021 | 61 | $139.0M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding X4 Pharmaceuticals, Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Empery Asset Management, LP | 8,951,105 | $35.8M | 31.57% | +8,951,105 | New |
| FMR LLC | 8,499,100 | $34.0M | 0.00% | +8,499,100 | New |
| Morgan Stanley | 8,208,015 | $32.8M | 0.00% | +8,204,287+220,072.1% | Added |
| Bain Capital Life Sciences Investors, LLC | 7,967,454 | $31.9M | 2.44% | +5,530,866+227.0% | Added |
| Perceptive Advisors LLC | 6,314,452 | $25.3M | 0.46% | +6,314,452 | New |
| Saturn V Capital Management LLC | 5,800,530 | $23.2M | 4.26% | +5,800,530 | New |
| Deep Track Capital, LP | 5,013,661 | $20.1M | 0.46% | +3,891,177+346.7% | Added |
| Kalehua Capital Management LLC | 3,722,840 | $14.9M | 14.73% | +3,722,840 | New |
| Vanguard Group Inc | 3,423,662 | $13.7M | 0.00% | +3,013,177+734.1% | Added |
| Braidwell LP | 3,368,904 | $13.5M | 0.43% | +3,368,904 | New |
| NEA Management Company, LLC | 3,233,743 | $12.9M | 0.66% | +1,000,000+44.8% | Added |
| Blackstone Group Inc. | 2,681,922 | $10.7M | 0.05% | +2,681,922 | New |
| Rosalind Advisors, Inc. | 2,605,920 | $10.4M | 3.80% | +1,061,313+68.7% | Added |
| Trails Edge Capital Partners, LP | 2,571,478 | $10.3M | 2.54% | +2,571,478 | New |
| Nantahala Capital Management, LLC | 2,449,468 | $9.80M | 0.58% | +221,118+9.9% | Added |
| BVF Inc | 2,233,742 | $8.93M | 0.30% | 00.0% | Unchanged |
| Samsara BioCapital, LLC | 1,960,000 | $7.84M | 0.81% | +1,960,000 | New |
| Siren, L.L.C. | 1,500,000 | $6.00M | 0.18% | +1,500,000 | New |
| BlackRock, Inc. | 1,226,808 | $4.91M | 0.00% | +1,164,874+1,880.8% | Added |
| Woodline Partners LP | 1,000,855 | $4.00M | 0.02% | +1,000,855 | New |
| Geode Capital Management, LLC | 940,447 | $3.76M | 0.00% | +860,789+1,080.6% | Added |
| StemPoint Capital LP | 898,465 | $3.59M | 0.62% | +343,054+61.8% | Added |
| Goldman Sachs Group Inc | 831,890 | $3.33M | 0.00% | +831,890 | New |
| Point72 Asset Management, L.P. | 808,154 | $3.23M | 0.01% | +786,488+3,630.1% | Added |
| Stonepine Capital Management, LLC | 593,573 | $2.37M | 1.88% | −462,765−43.8% | Reduced |
| Silverarc Capital Management, LLC | 357,387 | $1.43M | 0.21% | +357,387 | New |
| Acorn Capital Advisors, LLC | 273,349 | $1.09M | 0.37% | 00.0% | Unchanged |
| State Street Corp | 198,234 | $792.9K | 0.00% | +159,500+411.8% | Added |
| Northern Trust Corp | 178,235 | $712.9K | 0.00% | +178,235 | New |
| Pale Fire Capital SE | 167,590 | $670.4K | 0.09% | −13,261−7.3% | Reduced |
| Affinity Asset Advisors, LLC | 145,000 | $580.0K | 0.04% | +145,000 | New |
| Citadel Advisors LLC | 128,675 | $514.7K | 0.00% | +128,675 | New |
| Palumbo Wealth Management LLC | 113,357 | $453.4K | 0.11% | +18,030+18.9% | Added |
| Omers Administration Corp | 109,200 | $436.8K | 0.00% | +109,200 | New |
| Jane Street Group, LLC | 91,413 | $365.7K | 0.00% | +91,413 | New |
| Marshall Wace, LLP | 80,456 | $321.8K | 0.00% | +80,456 | New |
| ExodusPoint Capital Management, LP | 79,072 | $316.3K | 0.00% | +79,072 | New |
| Qube Research & Technologies Ltd | 67,747 | $271.0K | 0.00% | +67,747 | New |
| Charles Schwab Investment Management Inc | 66,788 | $267.2K | 0.00% | +66,788 | New |
| Balyasny Asset Management LLC | 64,505 | $258.0K | 0.00% | +64,505 | New |
| Barclays PLC | 57,500 | $230.0K | 0.00% | +57,500 | New |
| Millennium Management LLC | 55,978 | $223.9K | 0.00% | −8,817−13.6% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 43,259 | $173.0K | 0.00% | +43,259 | New |
| Bank of America Corp | 35,761 | $143.0K | 0.00% | +16,457+85.3% | Added |
| Citigroup Inc | 32,332 | $129.3K | 0.00% | +32,300+100,937.5% | Added |
| Hudson Bay Capital Management LP | 32,239 | $129.0K | 0.00% | +32,239 | New |
| Jefferies Financial Group Inc. | 26,118 | $104.5K | 0.00% | +26,118 | New |
| Man Group plc | 24,187 | $96.7K | 0.00% | +24,187 | New |
| Virtu Financial LLC | 22,489 | $90.0K | 0.00% | +22,489 | New |
| Lighthouse Investment Partners, LLC | 22,200 | $88.8K | 0.00% | +22,200 | New |
| Susquehanna International Group, LLP | 22,135 | $88.5K | 0.00% | +22,135 | New |
| Stifel Financial Corp | 20,496 | $82.0K | 0.00% | +20,496 | New |
| Two Sigma Investments, LP | 17,246 | $69.0K | 0.00% | +3,378+24.4% | Added |
| Creative Planning | 16,427 | $65.7K | 0.00% | +16,427 | New |
| Caxton Corp | 15,557 | $62.2K | 1.45% | +15,557 | New |
| Squarepoint Ops LLC | 12,518 | $50.1K | 0.00% | +12,518 | New |
| Tower Research Capital LLC (TRC) | 10,446 | $41.8K | 0.00% | −233−2.2% | Reduced |
| Indivisible Partners | 10,000 | $40.0K | 0.00% | +10,000 | New |
| JPMorgan Chase & Co | 4,581 | $18.3K | 0.00% | +4,548+13,781.8% | Added |
| UBS Group AG | 4,129 | $16.5K | 0.00% | −155,706−97.4% | Reduced |
| Group One Trading, L.P. | 3,998 | $16.0K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 2,754 | $11.0K | 0.00% | +2,754 | New |
| CIBC Private Wealth Group, LLC | 2,166 | $8.66K | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 1,759 | $7.04K | 0.00% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 729 | $2.92K | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 715 | $2.86K | 0.00% | +715 | New |
| Bleichroeder LP | 595 | $2.38K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 511 | $2.04K | 0.00% | −43−7.8% | Reduced |
| Farther Finance Advisors, LLC | 331 | $1.32K | 0.00% | +331 | New |
| Ronald Blue Trust, Inc. | 284 | $1.14K | 0.00% | 00.0% | Unchanged |
| Fortitude Family Office, LLC | 137 | $548 | 0.00% | +137 | New |
| SBI Securities Co., Ltd. | 50 | $200 | 0.00% | −166−76.9% | Reduced |
| Jones Financial Companies LLLP | 38 | $152 | 0.00% | 00.0% | Unchanged |
| GWM Advisors LLC | 33 | $132 | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 33 | $132 | 0.00% | 00.0% | Unchanged |
| RMG Wealth Management LLC | 28 | $64 | 0.00% | +28 | New |
| HighMark Wealth Management LLC | 6 | $24 | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 5 | $20 | 0.00% | +5 | New |
| Royal Bank of Canada | 104 | $0 | 0.00% | −2,429−95.9% | Reduced |
| Kingdon Capital Management, L.L.C. | 0 | $0 | 0.00% | −933,332−100.0% | Sold out |
| Boothbay Fund Management, LLC | 0 | $0 | 0.00% | −343,963−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −19,177−100.0% | Sold out |
| TD Waterhouse Canada Inc. | 0 | $0 | 0.00% | −1,500−100.0% | Sold out |
| Point72 Asia (Singapore) Pte. Ltd. | – | – | – | – | Not filed |