X4 Pharmaceuticals, Inc
XFOR- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001501697
In the last 90 days, X4 Pharmaceuticals, Inc insiders filed 0 open-market purchases and 3 sales; 89 institutions reported holding it in 13F filings for Q2 2026, worth $463.0M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in X4 Pharmaceuticals, Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 79
- +38 vs. Q3 2025
- Shares held
- 89.4M
- +73.3M (+453.5%) vs. Q3 2025
- Total value
- $357.7M
- +$302.5M (+547.4%) vs. Q3 2025
- New holders
- 42
- 17 more added
- Sold out
- 4
- 8 more reduced
1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XFOR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 89 | $463.0M |
| Q1 2026 | 84 | $388.1M |
| Q4 2025 | 79 | $357.7M |
| Q3 2025 | 42 | $55.3M |
| Q2 2025 | 52 | $5.33M |
| Q1 2025 | 94 | $23.3M |
| Q4 2024 | 90 | $73.2M |
| Q3 2024 | 98 | $67.3M |
| Q2 2024 | 99 | $58.9M |
| Q1 2024 | 98 | $143.2M |
| Q4 2023 | 93 | $81.2M |
| Q3 2023 | 91 | $122.6M |
| Q2 2023 | 96 | $219.1M |
| Q1 2023 | 59 | $53.6M |
| Q4 2022 | 54 | $60.2M |
| Q3 2022 | 59 | $66.9M |
| Q2 2022 | 51 | $15.5M |
| Q1 2022 | 56 | $28.6M |
| Q4 2021 | 52 | $40.2M |
| Q3 2021 | 52 | $85.7M |
| Q2 2021 | 63 | $107.8M |
| Q1 2021 | 61 | $138.7M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding X4 Pharmaceuticals, Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Royal Bank of Canada | 104 | $0 | 0.00% | −2,429−95.9% | Reduced |
| Northwestern Mutual Wealth Management Co | 5 | $20 | 0.00% | +5 | New |
| HighMark Wealth Management LLC | 6 | $24 | 0.00% | 00.0% | Unchanged |
| RMG Wealth Management LLC | 28 | $64 | 0.00% | +28 | New |
| GWM Advisors LLC | 33 | $132 | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 33 | $132 | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 38 | $152 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 50 | $200 | 0.00% | −166−76.9% | Reduced |
| Fortitude Family Office, LLC | 137 | $548 | 0.00% | +137 | New |
| Ronald Blue Trust, Inc. | 284 | $1.14K | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 331 | $1.32K | 0.00% | +331 | New |
| BNP Paribas Arbitrage, SA | 511 | $2.04K | 0.00% | −43−7.8% | Reduced |
| Bleichroeder LP | 595 | $2.38K | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 715 | $2.86K | 0.00% | +715 | New |
| Russell Investments Group, Ltd. | 729 | $2.92K | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 1,759 | $7.04K | 0.00% | 00.0% | Unchanged |
| CIBC Private Wealth Group, LLC | 2,166 | $8.66K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 2,754 | $11.0K | 0.00% | +2,754 | New |
| Group One Trading, L.P. | 3,998 | $16.0K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 4,129 | $16.5K | 0.00% | −155,706−97.4% | Reduced |
| JPMorgan Chase & Co | 4,581 | $18.3K | 0.00% | +4,548+13,781.8% | Added |
| Indivisible Partners | 10,000 | $40.0K | 0.00% | +10,000 | New |
| Tower Research Capital LLC (TRC) | 10,446 | $41.8K | 0.00% | −233−2.2% | Reduced |
| Squarepoint Ops LLC | 12,518 | $50.1K | 0.00% | +12,518 | New |
| Caxton Corp | 15,557 | $62.2K | 1.45% | +15,557 | New |
| Creative Planning | 16,427 | $65.7K | 0.00% | +16,427 | New |
| Two Sigma Investments, LP | 17,246 | $69.0K | 0.00% | +3,378+24.4% | Added |
| Stifel Financial Corp | 20,496 | $82.0K | 0.00% | +20,496 | New |
| Susquehanna International Group, LLP | 22,135 | $88.5K | 0.00% | +22,135 | New |
| Lighthouse Investment Partners, LLC | 22,200 | $88.8K | 0.00% | +22,200 | New |
| Virtu Financial LLC | 22,489 | $90.0K | 0.00% | +22,489 | New |
| Man Group plc | 24,187 | $96.7K | 0.00% | +24,187 | New |
| Jefferies Financial Group Inc. | 26,118 | $104.5K | 0.00% | +26,118 | New |
| Hudson Bay Capital Management LP | 32,239 | $129.0K | 0.00% | +32,239 | New |
| Citigroup Inc | 32,332 | $129.3K | 0.00% | +32,300+100,937.5% | Added |
| Bank of America Corp | 35,761 | $143.0K | 0.00% | +16,457+85.3% | Added |
| Susquehanna Portfolio Strategies, LLC | 43,259 | $173.0K | 0.00% | +43,259 | New |
| Millennium Management LLC | 55,978 | $223.9K | 0.00% | −8,817−13.6% | Reduced |
| Barclays PLC | 57,500 | $230.0K | 0.00% | +57,500 | New |
| Balyasny Asset Management LLC | 64,505 | $258.0K | 0.00% | +64,505 | New |
| Charles Schwab Investment Management Inc | 66,788 | $267.2K | 0.00% | +66,788 | New |
| Qube Research & Technologies Ltd | 67,747 | $271.0K | 0.00% | +67,747 | New |
| ExodusPoint Capital Management, LP | 79,072 | $316.3K | 0.00% | +79,072 | New |
| Marshall Wace, LLP | 80,456 | $321.8K | 0.00% | +80,456 | New |
| Jane Street Group, LLC | 91,413 | $365.7K | 0.00% | +91,413 | New |
| Omers Administration Corp | 109,200 | $436.8K | 0.00% | +109,200 | New |
| Palumbo Wealth Management LLC | 113,357 | $453.4K | 0.11% | +18,030+18.9% | Added |
| Citadel Advisors LLC | 128,675 | $514.7K | 0.00% | +128,675 | New |
| Affinity Asset Advisors, LLC | 145,000 | $580.0K | 0.04% | +145,000 | New |
| Pale Fire Capital SE | 167,590 | $670.4K | 0.09% | −13,261−7.3% | Reduced |
| Northern Trust Corp | 178,235 | $712.9K | 0.00% | +178,235 | New |
| State Street Corp | 198,234 | $792.9K | 0.00% | +159,500+411.8% | Added |
| Acorn Capital Advisors, LLC | 273,349 | $1.09M | 0.37% | 00.0% | Unchanged |
| Silverarc Capital Management, LLC | 357,387 | $1.43M | 0.21% | +357,387 | New |
| Stonepine Capital Management, LLC | 593,573 | $2.37M | 1.88% | −462,765−43.8% | Reduced |
| Point72 Asset Management, L.P. | 808,154 | $3.23M | 0.01% | +786,488+3,630.1% | Added |
| Goldman Sachs Group Inc | 831,890 | $3.33M | 0.00% | +831,890 | New |
| StemPoint Capital LP | 898,465 | $3.59M | 0.62% | +343,054+61.8% | Added |
| Geode Capital Management, LLC | 940,447 | $3.76M | 0.00% | +860,789+1,080.6% | Added |
| Woodline Partners LP | 1,000,855 | $4.00M | 0.02% | +1,000,855 | New |
| BlackRock, Inc. | 1,226,808 | $4.91M | 0.00% | +1,164,874+1,880.8% | Added |
| Siren, L.L.C. | 1,500,000 | $6.00M | 0.18% | +1,500,000 | New |
| Samsara BioCapital, LLC | 1,960,000 | $7.84M | 0.81% | +1,960,000 | New |
| BVF Inc | 2,233,742 | $8.93M | 0.30% | 00.0% | Unchanged |
| Nantahala Capital Management, LLC | 2,449,468 | $9.80M | 0.58% | +221,118+9.9% | Added |
| Trails Edge Capital Partners, LP | 2,571,478 | $10.3M | 2.54% | +2,571,478 | New |
| Rosalind Advisors, Inc. | 2,605,920 | $10.4M | 4.00% | +1,061,313+68.7% | Added |
| Blackstone Group Inc. | 2,681,922 | $10.7M | 0.05% | +2,681,922 | New |
| NEA Management Company, LLC | 3,233,743 | $12.9M | 0.66% | +1,000,000+44.8% | Added |
| Braidwell LP | 3,368,904 | $13.5M | 0.43% | +3,368,904 | New |
| Vanguard Group Inc | 3,423,662 | $13.7M | 0.00% | +3,013,177+734.1% | Added |
| Kalehua Capital Management LLC | 3,722,840 | $14.9M | 14.73% | +3,722,840 | New |
| Deep Track Capital, LP | 5,013,661 | $20.1M | 0.46% | +3,891,177+346.7% | Added |
| Saturn V Capital Management LLC | 5,800,530 | $23.2M | 4.26% | +5,800,530 | New |
| Perceptive Advisors LLC | 6,314,452 | $25.3M | 0.46% | +6,314,452 | New |
| Bain Capital Life Sciences Investors, LLC | 7,967,454 | $31.9M | 2.44% | +5,530,866+227.0% | Added |
| Morgan Stanley | 8,208,015 | $32.8M | 0.00% | +8,204,287+220,072.1% | Added |
| FMR LLC | 8,499,100 | $34.0M | 0.00% | +8,499,100 | New |
| Empery Asset Management, LP | 8,951,105 | $35.8M | 31.57% | +8,951,105 | New |
| Kingdon Capital Management, L.L.C. | 0 | $0 | 0.00% | −933,332−100.0% | Sold out |
| Boothbay Fund Management, LLC | 0 | $0 | 0.00% | −343,963−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −19,177−100.0% | Sold out |
| TD Waterhouse Canada Inc. | 0 | $0 | 0.00% | −1,500−100.0% | Sold out |
| Point72 Asia (Singapore) Pte. Ltd. | – | – | – | – | Not filed |